Table 1 Demographic and clinical characteristics of the included population

Number (Female/Male)

988 (301/687)

577 (293/284)

151 (8/143)

37 (0/37)

104 (0/104)

119 (0/119)

366 (8/358)

45 (0/45)

Age

63.2 ± 10.6

64.1 ± 11.0

61.5 ± 10.4

60.9 ± 10.5

63.0 ± 9.5

61.3 ± 9.5

61.4 ± 10.0

65.2 ± 8.6

BMI

24.2 ± 3.3

24.1 ± 3.5

24.6 ± 3.1

24.0 ± 3.5

24.1 ± 2.9

24.0 ± 2.9

24.3 ± 3.0

24.1 ± 2.7

Hypertension

740 (74.9%)

438 (75.9%)

106 (70.2%)

28 (75.7%)

77 (74.0%)

91 (76.5%)

268 (73.2%)

34 (75.6%)

 Regular treatment

323 (32.7%)

196 (34.0)

44 (29.1%)

12 (32.4%)

32 (30.8%)

39 (32.8%)

108 (29.5%)

19 (42.2%)

 Untreated or irregular treatment

417 (42.2%)

242 (41.9%)

62 (41.1%)

16 (43.2%)

45 (43.3%)

52 (43.7%)

160 (43.7%)

15 (33.3%)

Diabetes

271 (27.4%)

161 (27.9%)

46 (30.5%)

8 (21.6%)

24 (23.1%)

29 (24.4%)

92 (25.1%)

15 (33.3%)

 Regular treatment

186 (18.8%)

114 (19.8%)

29 (19.2%)

7 (18.9%)

17 (16.3%)

19 (16.0%)

63 (17.2%)

9 (20.0%)

 Untreated or irregular treatment

85 (8.6%)

50 (8.7%)

17 (11.3%)

1 (2.7%)

7 (6.7%)

10 (8.4%)

29 (7.9%)

6 (13.3%)

Coronary heart disease

108 (10.9%)

63 (10.9%)

19 (12.6%)

2 (5.4%)

10 (9.6%)

14 (11.8%)

37 (10.1%)

8 (17.8%)

Regular antiplatelet treatment

21 (2.1%)

15 (2.6%)

4 (2.6%)

1 (2.7%)

0 (0%)

1 (0.8%)

5 (1.4%)

1 (2.2%)

Regular statin treatment

22(2.2%)

15 (2.6%)

4 (2.6%)

1 (2.7%)

0 (0%)

2 (1.7%)

5 (1.4%)

2 (4.4%)

Gastrointestinal bleeding

69 (7.0%)

38 (6.6%)

9 (6.0%)

2 (5.6%)

13 (12.5%)

7 (5.9%)

30 (8.2%)

1 (2.2%)

Pneumonia

221 (22.4%)

114 (19.8%)

39 (25.8%)

9 (24.3%)

29 (27.9%)

30 (25.2%)

96 (26.2%)

11 (24.4%)

Smoking status

 Current smokers

376 (38.1%)

84 (14.6%)

99 (65.6%)

28 (75.7%)

73 (70.2%)

92 (77.3%)

270 (73.8%)

22 (48.9%)

 Former smokers

64 (6.5%)

10 (1.7%)

13 (8.6%)

3 (8.1%)

23 (22.1%)

15 (12.6%)

34 (9.3%)

20 (44.4%)

 Non-smokers

548 (55.4%)

483 (83.7%)

39 (25.8%)

6 (16.2%)

8 (7.7%)

12 (10.1%)

62 (16.9%)

3 (6.7%)

Leukocyte counts (10⁹/L)

8.7 ± 3.2

8.7 ± 3.4

9.0 ± 2.95

8.1 ± 2.2

8.3 ± 2.7

8.7 ± 3.6

8.7 ± 3.1

8.5 ± 2.7

Neutrophil counts (10⁹/L)

6.5 ± 3.2

6.5 ± 3.3

6.9 ± 3.0

6.1 ± 2.2

6.3 ± 2.6

6.5 ± 3.7

6.5 ± 3.1

6.6 ± 2.6

Lymphocyte counts (10⁹/L)

1.6 ± 0.7

1.6 ± 0.7

1.6 ± 0.8

1.4 ± 0.5

1.4 ± 0.6

1.6 ± 0.6

1.5 ± 0.7

1.4 ± 0.6

Triglyceride

1.8 ± 1.3

1.8 ± 1.3

1.8 ± 1.4

1.9 ± 1.8

1.7 ± 1.1

1.9 ± 1.2

1.8 ± 1.3

1.7 ± 1.3

Low density lipoprotein

3.0 ± 0.9

3.0 ± 0.9

3.1 ± 0.9

3.1 ± 1.1

2.9 ± 0.9

2.8 ± 0.9

3.0 ± 0.9

3.0 ± 1.0

High density lipoprotein

1.3 ± 0.4

1.3 ± 0.4

1.2 ± 0.3

1.2 ± 0.4

1.3 ± 0.4

1.3 ± 0.5

1.2 ± 0.4

1.2 ± 0.3

Creatinine

70.1 ± 19.2

67.1 ± 18.9

73.7 ± 18.2

72.1 ± 18.8

75.0 ± 18.9

75.2 ± 19.4

73.8 ± 18.5

78.9 ± 20.0

Glomerular filtration rate

93.1 ± 20.6

92.1 ± 20.4

95.5 ± 24.2

98.5 ± 24.1

93.1 ± 16.6

93.1 ± 17.9

95.2 ± 21.0

88.7 ± 17.1

Uric acid

339.0 ± 96.4

321.9 ± 92.2

355.7 ± 94.3

387.0 ± 121.1

359.6 ± 88.0

367.9 ± 100.0

362.7 ± 97.8

365.8 ± 92.8

NIHSS score on admission

6.6 ± 5.9

6.5 ± 5.8

6.5 ± 6.8

6.6 ± 5.6

7.4 ± 5.0

6.4 ± 5.7

6.7 ± 6.0

6.7 ± 5.9

NIHSS score at discharge

6.1 ± 8.4

5.8 ± 8.2

6.2 ± 8.3

4.5 ± 3.9

7.2 ± 9.5

6.5 ± 9.5

6.4 ± 8.5

6.2 ± 10.3

mRS score on admission

2.7 ± 1.4

2.6 ± 1.4

2.6 ± 1.4

2.7 ± 1.3

2.9 ± 1.3

2.6 ± 1.5

2.7 ± 1.4

2.6 ± 1.5

mRS score at discharge

2.2 ± 1.6

2.1 ± 1.6

2.2 ± 1.6

2.1 ± 1.3

2.5 ± 1.7

2.2 ± 1.8

2.3 ± 1.6

2.0 ± 1.7