An observational time-series study on the behavioral effects of adjunctive artisanal cannabidiol use by adults with treatment resistant epilepsies

Table 2 Post-hoc analyses

	F statistic	P value	Partial Eta squared	Pairwise comparisons w/Bonferroni correction
QOLIE-31-P: 1-Way Repeated Measures ANOVA with factor of TIME (3 levels)
Subscale A (Energy)	3.851	0.041^*	0.300	NS
Subscale B (Mood)	4.650	0.024^*	0.341	NS
Subscale C (Daily Activities)	4.459	0.027^*	0.331	T1 Sigdif T3 (p = 0.032)
Subscale D (Cognition)	6.046	0.010^*	0.402	T1 Sigdif T3 (p = 0.032)
Subscale E (Medication Effects; n = 8)	0.992	0.396	0.124	N.A.
Subscale F (Seizure Worry)	8.070	0.003 (G-G = 0.014^*)	0.473	T1 Sigdif T3 (p = 0.041)
Subscale G (Overall Quality of Life)	5.328	0.015^*	0.372	NS
Subscale (Distress)	8.687	0.002 (G-G = 0.010^*)	0.491	T1 Sigdif T3 (p = 0.036
HADS: 1-Way Repeated Measures ANOVAS with factors of TIME (3 levels)
TIME (ANXIETY)	5.718	0.012^*	0.388	T1 Sigdif T3 (p = 0.021
TIME (DEPRESSION)	2.859	0.083	0.241	T1 Sigdif T3 (p = 0.013

(top) shows the results of multiple one-way repeated measures ANOVAS on SUBSCALE data from the QOLIE-31-P with a factor of TIME (3 levels), along with the results of Bonferroni-corrected pairwise comparisons. Table 22 (middle) shows the results of a one-way repeated measures ANOVA on data from the HADS ANXIETY SUBSCALE with a factor of TIME (3 levels), along with the results of Bonferroni-corrected pairwise comparisons. Table 22 (bottom) shows the results of a one-way repeated measures ANOVA on data from the HADS DEPRESSION SUBSCALE with a factor of TIME (3 levels), along with the results of Bonferroni-corrected pairwise comparisons
G-G = Greenhouse-Geisser correction for Mauchly’s Test of Sphericity violation
T = Time 1, 2, 3, Sigdif Statistically significant difference, NS No statistically significant difference
*p < 0.05

ISSN: 1471-2377