Articles
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Citation: BMC Neurology 2022 22:374
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Case report of two affected siblings in a family with thiamine metabolism dysfunction syndrome 5: a rare, but treatable neurodegenerative disease
Thiamine metabolism dysfunction syndrome 5 (THMD5) is a rare inherited metabolic disorder due to thiamine pyrophosphokinase 1(TPK1) deficiency, caused by mutations in TPK1. The core symptoms of the disease is acu...
Citation: BMC Neurology 2022 22:373 -
Assessment of sexual dysfunction in patients with multiple sclerosis: a perspective from neurologist
Sexual dysfunction (SD) is a common comorbidity in people with multiple sclerosis (pwMS). It affects the quality of life and remains an overlooked condition. The objective of this study was to describe how Col...
Citation: BMC Neurology 2022 22:372 -
Secondary autoimmune hypothalamitis with severe memory impairment 7 years after the onset of diabetes insipidus due to lymphocytic hypophysitis: a case report
Autoimmune hypothalamitis is a very rare neuroendocrine disorder that causes central diabetes insipidus, headache, visual impairment, and sometimes cognitive impairment. Autoimmune hypothalamitis may occur in ...
Citation: BMC Neurology 2022 22:371 -
Binary effects of intravascular laser irradiation of blood on motor recovery and homocysteine reduction in a case with ischemic hemiparesis: portrayed with brain perfusion images
Stroke is a burdensome cerebral eventthat affects many aspects of daily activities such as motion, speech, memory, vision, and cognition. Intravascular laser irradiation of blood (ILIB) is a novel therapy, goi...
Citation: BMC Neurology 2022 22:370 -
A case report of unilateral cervical lymphadenopathy and multiple cranial neuropathies following mRNA-COVID-19 vaccination
We report a rare case of ipsilateral multiple cranial neuropathy and ipsilateral lymphadenopathy following mRNA-COVID-19 vaccination.
Citation: BMC Neurology 2022 22:369 -
Progressive sensory ataxia and breast implant rupture, an uncommon presentation of a debated concept: a case report
Autoimmune Syndrome Induced by Adjuvants (ASIA) is a concept introduced by Shoenfeld to group various disease entities believed to be triggered by an infection, silicone exposure or other external stimuli. A c...
Citation: BMC Neurology 2022 22:368 -
Survival in patients with Parkinson’s disease: a ten-year follow-up study in northern China
A thorough understanding of the factors that influence patient survival in Parkinson’s disease (PD) will aid in prognosis prediction and provide a new direction for disease modification treatment. Currently, t...
Citation: BMC Neurology 2022 22:367 -
Colostomy as a definitive treatment in an ALS patient with acute colonic Pseudo-obstruction refractory to medical management, a case report
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease, and ALS patients may experience disturbed gastrointestinal motility often resulting in acute colonic pseudo-obstruction (ACPO). There is cur...
Citation: BMC Neurology 2022 22:366 -
Continuous monitoring of brain perfusion by cerebral oximetry after spontaneous return of circulation in cardiac arrest: a case report
Cerebral resuscitation determines the prognosis for patients who have experienced sudden death, and brain protection is the focus of clinical treatment. Cerebral resuscitation depends on the timing and quality...
Citation: BMC Neurology 2022 22:365 -
Clinical factors associated with cerebral autoregulation in ischemic stroke related to small artery occlusion
Existing data suggest that cerebral autoregulation (CA) varies among different subtypes of ischaemic stroke. CA is globally impaired in patients with small artery occlusion (SAO). However, the factors influenc...
Citation: BMC Neurology 2022 22:364 -
Ischemic stroke in young patients in Medellín, Colombia
There is scarce information about ischemic stroke in young patients in Colombia. To get insights about this phenomenon, this study describes the etiologies and risk factors of ischemic stroke in young patients...
Citation: BMC Neurology 2022 22:363 -
Long-segment spinal cord infarction complicated with multiple cerebral infarctions: a case report
Spinal cord infarction is a rare disorder, constituting only 1% to 2% of all neurological vascular emergencies (making it less frequent than ischaemic brain injury); however, it is severe. A case of long-segme...
Citation: BMC Neurology 2022 22:362 -
Association between participation self-efficacy and participation in stroke survivors
Most stroke survivors face restrictions in functional disability and social participation, which can impede their recovery and community reintegration. Participation self-efficacy refers to survivors’ confiden...
Citation: BMC Neurology 2022 22:361 -
Investigating the effect of self-management program on stroke’s patients’ self-efficacy
Stroke patients face various challenges that affect their self-efficacy. The purpose of this study is to evaluate the effect of a self-management program on the self-efficacy of patients with Stroke.
Citation: BMC Neurology 2022 22:360 -
Immediate outcome prognostic value of plasma factors in patients with acute ischemic stroke after intravenous thrombolytic treatment
In the present study, we explored multiple plasma factors to predict the outcomes of patients with AIS after IVT. Fifty AIS patients who received IVT with alteplase were recruited and divided into two groups a...
Citation: BMC Neurology 2022 22:359 -
Periostin and TNF-α expression levels in peripheral blood of patients with acute cerebral infarction combined with obstructive sleep apnea syndrome and their predictive value for clinical prognosis
To detect the expression levels of periostin and tumour necrosis factor-α (TNF-α) in patients with acute cerebral infarction (ACI) combined with obstructive sleep apnea syndrome (OSAS) and to investigate their...
Citation: BMC Neurology 2022 22:358 -
Risk factors for aneurysm rupture among Kazakhs: findings from a national tertiary hospital
Rupture of intracranial aneurysms (RIA) leads to subarachnoid hemorrhage (SAH) with severe consequences. Although risks for RIA are established, the results vary between ethnic groups and were never studied in...
Citation: BMC Neurology 2022 22:357 -
Kynurenine and oxidative stress in children having learning disorder with and without attention deficit hyperactivity disorder: possible role and involvement
The etiological and pathophysiological factors of learning disorder (LD) and attention deficit hyperactivity disorder (ADHD) are currently not well understood. These disorders disrupt some cognitive abilities....
Citation: BMC Neurology 2022 22:356 -
The presence and co-incidence of geriatric syndromes in older patients with mild-moderate Lewy body dementia
Geriatric symptoms are common in dementia cases, while few studies have focused on these symptoms in Lewy body dementia (LBD). The purpose of this study is to investigate the distributions of Apolipoprotein E ...
Citation: BMC Neurology 2022 22:355 -
Orbital apex syndrome secondary to apical periodontitis of a tooth: a case report
Orbital apex syndrome (OAS) is a rare disease with a noticeable mortality rate. Although its etiology has been repeatedly assessed, few reports have concentrated on odontogenic infection. We presented a rare c...
Citation: BMC Neurology 2022 22:354 -
Neuroanatomical regions associated with non-progressive dysarthria post-stroke: a systematic review
Dysarthria is a common and persisting sequela to stroke. It can have a negative influence on psychological wellbeing, and quality of life. This systematic review aimed to describe and identify the neuroanatomi...
Citation: BMC Neurology 2022 22:353 -
Hyperperfusion in the cerebellum lobule VIIb in patients with epileptic seizures
The cerebellum plays an important role in motor control, however, its involvement in epilepsy has not been fully understood. Arterial spin labelling perfusion magnetic resonance image (ASL) is a noninvasive me...
Citation: BMC Neurology 2022 22:352 -
Intracranial stenting as a bail-out option for posthemorrhagic cerebral vasospasm: a single-center experience with long-term follow-up
Cerebral vasospasm (CVS) is a leading cause of morbidity and mortality in patients after aneurysmal subarachnoid hemorrhage (aSAH). Endovascular treatment, including intraarterial infusion of drugs with vasodi...
Citation: BMC Neurology 2022 22:351 -
Exploring the relationship between age and prognosis in glioma: rethinking current age stratification
The age of glioma plays a unique role in prognosis. We hypothesized that age is not positively correlated with survival prognosis and explored its exact relationship.
Citation: BMC Neurology 2022 22:350 -
In-hospital clinical outcomes in diffusion weighted imaging-negative stroke treated with intravenous thrombolysis
We aimed to investigate whether negative diffusion weighted imaging (DWI) is related to the in-hospital clinical outcomes for ischemic stroke patients with intravenous tissues plasminogen activator (IV tPA).
Citation: BMC Neurology 2022 22:349 -
Timing matters: there are significant differences in short-term outcomes between two time points of status epilepticus
In 2015, the International League Against Epilepsy proposed a new conceptual definition of status epilepticus (SE) with two operational dimensions (t1 and t2) to guide emergency treatment. The purpose of this ...
Citation: BMC Neurology 2022 22:348 -
Public and outpatients’ awareness of calling emergency medical services immediately by acute stroke in an upper middle-income country: a cross-sectional questionnaire study in greater Gaborone, Botswana
In this cross-sectional study from Botswana, we investigated awareness of calling emergency medical services (EMS) and seeking immediate medical assistance by acute stroke among stroke risk outpatients and pub...
Citation: BMC Neurology 2022 22:347 -
Predictors of recurrence of chronic subdural haematoma in a cohort study of patients presenting in a sub-Saharan African teaching hospital
Chronic subdural haematoma (CSDH) is a common neurological condition affecting the elderly with decreased quality of life. Recurrence leads to increase in number of hospital admissions and surgical interventio...
Citation: BMC Neurology 2022 22:346 -
Optimal therapeutic conditions for the neural stem cell-based management of ischemic stroke: a systematic review and network meta-analysis based on animal studies
In order to promote the clinical translation of preclinical findings, it is imperative to identify the most optimal therapeutic conditions and adopt them for further animal and human studies. This study aimed ...
Citation: BMC Neurology 2022 22:345 -
A case of novel DYT6 dystonia variant with serious complications after deep brain stimulation therapy: a case report
DYT6 dystonia belongs to a group of isolated, genetically determined, generalized dystonia associated with mutations in the THAP1 gene.
Citation: BMC Neurology 2022 22:344 -
Correction: Early neurological deterioration in acute ischemic stroke patients after intravenous thrombolysis with alteplase predicts poor 3-month functional prognosis - data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China)
Citation: BMC Neurology 2022 22:343 -
Endovascular recanalization of acute ischemic stroke patients exhibiting large vessel occlusion after pulmonary lobectomy: case series
We analyzed the outcomes of patients suffering acute ischemic stroke (AIS) with large vessel occlusion (LVO) soon after pulmonary lobectomy.
Citation: BMC Neurology 2022 22:342 -
Effect of insomnia in the major depressive disorder
People with sleep problems are more likely to have mental disorders. This study aimed to assess the effect of insomnia on the prognosis of patients with major depressive disorder (MDD).
Citation: BMC Neurology 2022 22:341 -
Evaluation of the epidemiologic, clinical, radiologic, and treatment methods of patients with subacute and chronic meningitis
Meningitis is known as a meningeal inflammation accompanied by pleocytosis in the cerebrospinal fluid (CSF), and can be classified into acute, subacute, and chronic meningitis based on symptoms duration of ≤ 5...
Citation: BMC Neurology 2022 22:340 -
Power spectral analysis of heart rate variability is useful as a screening tool for detecting sympathetic and parasympathetic nervous dysfunctions in Parkinson’s disease
Parkinson’s disease (PD) is a progressive neurodegenerative disorder that causes motor symptoms and autonomic dysfunction. However, autonomic function tests commonly performed in PD can only evaluate either th...
Citation: BMC Neurology 2022 22:339 -
Impact of D-dimer for pathologic differentiation on transesophageal echocardiography in embolic stroke of undetermined source: a single-center experience
Embolic stroke of undetermined source (ESUS) encompasses diverse embologenic mechanisms, which transesophageal echocardiography (TEE) is critical to detect. Specific markers related to each embolic source in E...
Citation: BMC Neurology 2022 22:338 -
Correction: IL6 trans-signaling associates with ischemic stroke but not with atrial fibrillation
Citation: BMC Neurology 2022 22:337 -
Brain regions involved in fractional amplitude of low-frequency fluctuation in cluster headache patients: a resting-state functional MRI study
We used resting-state functional magnetic resonance imaging (RS-fMRI) to assess the possible pathogenic role of fALFF in CH. A limited number of studies have reported on fractional amplitude of low-frequency f...
Citation: BMC Neurology 2022 22:336 -
Stroke in young adults, stroke types and risk factors: a case control study
Stroke is the second leading cause of death above the age of 60 years, and the fifth leading cause in people aged 15 to 59 years old as reported by the World Health Organization global burden of diseases. Stro...
Citation: BMC Neurology 2022 22:335 -
Predictive nomogram for soft robotic hand rehabilitation of patients with intracerebral hemorrhage
Few studies focused on the risk factors for hand rehabilitation of intracerebral hemorrhage (ICH) using of soft robotic hand therapy (SRHT). The aim of this study was to establish a predictive nomogram for sof...
Citation: BMC Neurology 2022 22:334 -
Validity of the Early Functional Ability scale (EFA) among critically ill patients undergoing early neurological rehabilitation
A reliable assessment of the functional abilities of patients after severe brain damage is crucial for valid prognostication and treatment decisions, but most clinical scales are of limited use among this spec...
Citation: BMC Neurology 2022 22:333 -
Risk factors for early neurological deterioration in acute isolated pontine infarction without any causative artery stenosis
This study aimed to investigate the risk predictors for early neurological deterioration (END) in isolated acute pontine infarction without any causative artery stenosis.
Citation: BMC Neurology 2022 22:332 -
Clinical features, etiology, and prognosis of hand knob stroke: a case series
Hand knob stroke is a rare clinical disorder frequently misdiagnosed as peripheral neuropathy. The purpose of this study is to recognize this particular type of stroke by analyzing clinical features, etiology,...
Citation: BMC Neurology 2022 22:331 -
Higher serum albumin-corrected calcium levels are associated with revascularization and poor outcome after mechanical thrombectomy
Serum calcium abnormalities have been determined to be associated with the risk and outcome of stroke. The aim of the present study was to examine the associations of serum calcium with vascular recanalization...
Citation: BMC Neurology 2022 22:330 -
Adult-onset Still’s disease with concurrent acute necrotizing encephalopathy: a case report
Acute necrotizing encephalopathy (ANE) is a rare encephalopathy characterized by multiple symmetrical brain lesions, mainly involving thalami. Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory...
Citation: BMC Neurology 2022 22:329 -
Incidence of and predictors for antiseizure medication gaps in Medicare beneficiaries with epilepsy: a retrospective cohort study
For the two-thirds of patients with epilepsy who achieve seizure remission on antiseizure medications (ASMs), patients and clinicians must weigh the pros and cons of long-term ASM treatment. However, little wo...
Citation: BMC Neurology 2022 22:328 -
Effect of β2-microglobulin in evaluating the severity and prognosis of brain injury: a clinical study
β2-microglobulin has been showing to be vital that associated with brain function and neurological diseases. This study aimed to explore the expressions of β2-microglobulin in blood and urine of the patients w...
Citation: BMC Neurology 2022 22:327 -
Prolonged increased neutrophil-to-lymphocyte ratio is associated with mortality after successful revascularization for treatment of acute ischemic stroke
To determine the association between dynamic neutrophil-to-lymphocyte ratio (NLR) during hospitalization and mortality 1 month after ischemia reperfusion in patients undergoing endovascular treatment (EVT) wit...
Citation: BMC Neurology 2022 22:326 -
Perioperative stroke during carotid endarterectomy: benefits of multimodal neuromonitoring - a case report
Carotid endarterectomy is routinely performed after ischemic stroke due to carotid stenosis. Perioperative, cerebral blood flow and oxygenation can be monitored in different ways, but there is no clear evidenc...
Citation: BMC Neurology 2022 22:325
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