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  1. Maintaining cognitive function is essential for healthy aging and to function autonomously within society. White matter lesions (WMLs) are associated with reduced cognitive function in older adults. However, w...

    Authors: Niousha Bolandzadeh, Jennifer C Davis, Roger Tam, Todd C Handy and Teresa Liu-Ambrose
    Citation: BMC Neurology 2012 12:126
  2. Hyperekplexia (HPX) is a rare non-epileptic disorder manifesting immediately after birth with exaggerated persistent startle reaction to unexpected auditory, somatosensory and visual stimuli, and non-habituati...

    Authors: Mohammed Zein Seidahmed, Mustafa A Salih, Omer B Abdulbasit, Meeralebbae Shaheed, Khalid Al Hussein, Abeer M Miqdad, Abdullah K Al Rasheed, Anas M Alazami, Ibrahim A Alorainy and Fowzan S Alkuraya
    Citation: BMC Neurology 2012 12:125
  3. Only few studies have assessed safety of in utero exposure to glatiramer acetate (GA). Following a previous study assessing the safety of interferon beta (IFNB) pregnancy exposure in multiple sclerosis (MS), w...

    Authors: Marta Giannini, Emilio Portaccio, Angelo Ghezzi, Bahia Hakiki, Luisa Pastò, Lorenzo Razzolini, Elisa Piscolla, Laura De Giglio, Carlo Pozzilli, Damiano Paolicelli, Maria Trojano, Maria Giovanna Marrosu, Francesco Patti, Loredana La Mantia, Gianluigi Mancardi, Claudio Solaro…
    Citation: BMC Neurology 2012 12:124
  4. Pyrexia after stroke (temperature ≥37.5°C) is associated with poor prognosis, but information on timing of body temperature changes and relationship to stroke severity and subtypes varies.

    Authors: Bartosz Karaszewski, Ralph GR Thomas, Martin S Dennis and Joanna M Wardlaw
    Citation: BMC Neurology 2012 12:123
  5. Chronic fatigue and inactivity are prevalent problems among individuals with multiple sclerosis (MS) and may independently or interactively have detrimental effects on quality of life and ability to participat...

    Authors: Matthew Plow, Marcia Finlayson, Robert W Motl and Francois Bethoux
    Citation: BMC Neurology 2012 12:122
  6. Progressive multifocal leukoencephalopathy (PML), a rare but fatal demyelinating disease caused by JC virus (JCV), occurs mainly in immunocompromised patients. As PML develops in individuals with various under...

    Authors: Kazuo Nakamichi, Hidehiro Mizusawa, Masahito Yamada, Shuji Kishida, Yoshiharu Miura, Toshio Shimokawa, Tomohiko Takasaki, Chang-Kweng Lim, Ichiro Kurane and Masayuki Saijo
    Citation: BMC Neurology 2012 12:121
  7. Tourette syndrome is a neuropsychiatric disorder characterized by motor and phonic tics. Deficient motor inhibition underlying tics is one of the main hypotheses in its pathophysiology. Therefore the question ...

    Authors: Irene Neuner, Jorge Arrubla, Corinna Ehlen, Hildegard Janouschek, Carlos Nordt, Bruno Fimm, Frank Schneider, N Jon Shah and Wolfram Kawohl
    Citation: BMC Neurology 2012 12:120
  8. Mild cognitive impairment (MCI), defined as a transitional zone between normal cognition and dementia, requires a battery of formal neuropsychological tests administered by a trained rater for its diagnosis. T...

    Authors: Qi-hao Guo, Bin Zhou, Qian-hua Zhao, Bei Wang and Zhen Hong
    Citation: BMC Neurology 2012 12:119
  9. Family function may have an influence on the mental health deterioration of the caregivers of dependent family members and it could have a varying importance on the care of dependents. Little attention has bee...

    Authors: Vicente Gil-Guillen, Concepcion Carratala-Munuera, Juan Carlos Andres Ortega, Domingo Orozco-Beltran, José Martínez Ribera, Avelino Pereira Expósito, Pablo Martínez Cánovas, Eduardo Payá Mora, Emilio Mayoral Azofra, Antonio Fernández Giménez, Adriana Lopez-Pineda, Patricia Lorca-Amorrich, Carlos Plaza-Sirvent, Elisabet Berzosa Sola, Ramon Salas-Rico and Angel Fernandez-Garcia
    Citation: BMC Neurology 2012 12:118
  10. Data about the risk factors of stroke are sparse in the Middle East populations. We aimed to determine the potential risk factors and their population attributable fraction (PAF) for stroke in an Iranian popul...

    Authors: Noushin Fahimfar, Davood Khalili, Reza Mohebi, Fereidoun Azizi and Farzad Hadaegh
    Citation: BMC Neurology 2012 12:117
  11. Randomized controlled trials (RCT) on the treatment of severe space-occupying infarction of the middle cerebral artery (malignant MCA infarction) showed that early decompressive hemicraniectomy (DHC) is life s...

    Authors: Hermann Neugebauer, Peter U Heuschmann and Eric Jüttler
    Citation: BMC Neurology 2012 12:115
  12. There are many drugs recommended for pain relief in patients with migraine headache.

    Authors: Hassan Soleimanpour, Rouzbeh Rajaei Ghafouri, Aliakbar Taheraghdam, Dawood Aghamohammadi, Sohrab Negargar, Samad EJ Golzari and Mohsen Abbasnezhad
    Citation: BMC Neurology 2012 12:114
  13. Patients with Parkinson's disease have an elevated risk of pneumonia and randomized trials suggest that this risk may be increased with the dopamine agonist pramipexole. It is uncertain whether pramipexole or ...

    Authors: Pierre Ernst, Christel Renoux, Sophie Dell'Aniello and Samy Suissa
    Citation: BMC Neurology 2012 12:113
  14. Kikuchi Fujimoto disease (KFD), or histiocytic necrotising lymphadenitis, is a benign and self-limiting condition characterised by primarily affecting the cervical lymph nodes. Recurrent aseptic meningitis in ...

    Authors: Tomoko Komagamine, Takahide Nagashima, Masaru Kojima, Norito Kokubun, Toshiki Nakamura, Kenich Hashimoto, Kazuhito Kimoto and Koichi Hirata
    Citation: BMC Neurology 2012 12:112
  15. There is increasing scientific knowledge about the interaction between physiological (musculoskeletal, neuromuscular, cognitive and sensory) systems and their influence on balance and walking impairments in Pa...

    Authors: David Conradsson, Niklas Löfgren, Agneta Ståhle, Maria Hagströmer and Erika Franzén
    Citation: BMC Neurology 2012 12:111
  16. Essential tremor (ET) is one of the commonest movement disorders though the prevalence varies globally. There is paucity of data on ET prevalence in sub-Saharan Africa. The study aimed to determine the prevale...

    Authors: Njideka U Okubadejo, Idowu A Bankole, Oluwadamilola O Ojo, Frank I Ojini and Mustapha A Danesi
    Citation: BMC Neurology 2012 12:110
  17. Swirl sign has previously been described in epidural hematomas as areas of low attenuation, radiolucency or irregular density. The aims of this study were to describe swirl sign in ICH, study its prevalence, s...

    Authors: Eufrozina Selariu, Elisabet Zia, Marco Brizzi and Kasim Abul-Kasim
    Citation: BMC Neurology 2012 12:109
  18. Adrenomyeloneuropathy (AMN) is one of several phenotypes of the adrenoleukodystrophy spectrum caused by mutations in the ABCD1 gene on the X chromosome. An inflammatory component is part of the disease complex ra...

    Authors: Aia Elise Jønch, Else Rubæk Danielsen, Carsten Thomsen, Per Meden, Kirsten Svenstrup and Jørgen Erik Nielsen
    Citation: BMC Neurology 2012 12:108
  19. In previous studies we found that MHC2TA +1614 genotype frequency was very different when MS patients with and without human herpesvirus 6 (HHV-6) in serum samples were compared; a different clinical behavior ...

    Authors: Maria Inmaculada Dominguez-Mozo, Marta Garcia-Montojo, Virginia De Las Heras, Angel Garcia-Martinez, Ana Maria Arias-Leal, Ignacio Casanova, Rafael Arroyo and Roberto Alvarez-Lafuente
    Citation: BMC Neurology 2012 12:107
  20. Life satisfaction (LS) of cerebrovascular disease survivors and their family caregivers may relate to socioeconomic factors, impaired functions, health-related quality of life (QoL), but their respective influ...

    Authors: Michèle Baumann, Sophie Couffignal, Etienne Le Bihan and Nearkasen Chau
    Citation: BMC Neurology 2012 12:105
  21. The mammalian neurological disorder hereditary hyperekplexia can be attributed to various mutations of strychnine sensitive glycine receptors. The clinical symptoms of “startle disease” predominantly occur in ...

    Authors: Jeanne de la Roche, Martin Leuwer, Klaus Krampfl, Gertrud Haeseler, Reinhard Dengler, Vanessa Buchholz and Jörg Ahrens
    Citation: BMC Neurology 2012 12:104
  22. Low levels of plasma 25-hydroxyvitaminD (25(OH)D) are associated with a higher incidence of multiple sclerosis (MS) due to the immune suppressive properties of vitamin D.

    Authors: Laia Grau-López, Maria Luisa Granada, Dàlia Raïch-Regué, Mar Naranjo-Gómez, Francesc E Borràs-Serres, Eva Martínez-Cáceres and Cristina Ramo-Tello
    Citation: BMC Neurology 2012 12:103
  23. Patients in neurologic in-patient rehabilitation are at risk of cardio- and cerebrovascular events. Microalbuminuria (MAU) is frequent and an important risk predictor but has not been validated in in-patient r...

    Authors: Dirk Sander, Christian Weimar, Peter Bramlage, Tobias Brandt, Ludger Rosin and Mario Siebler
    Citation: BMC Neurology 2012 12:102
  24. Neurogenic claudication (NC) is a common symptom in patients with lumbar spinal stenosis (LSS). The Neurogenic Claudication Outcome Score (NCOS) is a very short instrument for measuring functional status in th...

    Authors: Parisa Azimi, Hassan Reza Mohammadi and Ali Montazeri
    Citation: BMC Neurology 2012 12:101
  25. We noticed that a hypothesis based on the effect of geomagnetic disturbances (GMD) has the ability to explain special features of multiple sclerosis (MS). Areas around geomagnetic 60 degree latitude (GM60L) ex...

    Authors: Seyed Aidin Sajedi and Fahimeh Abdollahi
    Citation: BMC Neurology 2012 12:100
  26. Chronic low back pain (CLBP) has been shown to be associated with various pathophysiological changes at several level of the sensorimotor system, pointing to a general hypersensitivity in CLBP patients. The ai...

    Authors: Christian Puta, Birgit Schulz, Saskia Schoeler, Walter Magerl, Brunhild Gabriel, Holger H W Gabriel, Wolfgang H R Miltner and Thomas Weiss
    Citation: BMC Neurology 2012 12:98
  27. This article reports a rare case of active neurosyphilis in a man with mild to moderate dementia and marked hippocampal atrophy, mimicking early onset Alzheimer’s disease. Few cases have so far described bilat...

    Authors: Shima Mehrabian, Margarita Raycheva, Martina Traykova, Tonya Stankova, Latchezar Penev, Olga Grigorova and Latchezar Traykov
    Citation: BMC Neurology 2012 12:96
  28. The balance between T helper cells Th2- and Th1-related cytokines plays a key role in multiple sclerosis (MS). A shift from a Th1 towards a Th2 cytokine profile could have a beneficial effect on the clinical c...

    Authors: Celia Oreja-Guevara, Jaime Ramos-Cejudo, Luiz Stark Aroeira, Beatriz Chamorro and Exuperio Diez-Tejedor
    Citation: BMC Neurology 2012 12:95
  29. Multiple sclerosis (MS) is a chronic progressive neurological disease and the majority of patients will experience some degree of impaired mobility. We evaluated the prevalence, severity and burden of walking ...

    Authors: James Pike, Edward Jones, Krithika Rajagopalan, James Piercy and Peter Anderson
    Citation: BMC Neurology 2012 12:94
  30. Recently, heterozygous mutations in PRRT2 (Chr 16p11.2) have been identified in Han Chinese, Japanese and Caucasians with paroxysmal kinesigenic dyskinesia. In previous work, a paroxysmal kinesigenic dyskinesia l...

    Authors: Peter Hedera, Jianfeng Xiao, Andreas Puschmann, Dragana Momčilović, Steve W Wu and Mark S LeDoux
    Citation: BMC Neurology 2012 12:93
  31. Compensation of brain injury in multiple sclerosis (MS) may in part work through mechanisms involving neuronal plasticity on local and interregional scales. Mechanisms limiting excessive neuronal activity may ...

    Authors: Daniel Zeller, Su-Yin Dang, David Weise, Peter Rieckmann, Klaus V Toyka and Joseph Classen
    Citation: BMC Neurology 2012 12:92
  32. The aim of this study was to perform a longitudinal assessment using Quantitative Muscle Testing (QMT) in a cohort of ambulant boys affected by Duchenne muscular dystrophy (DMD) and to correlate the results of...

    Authors: Alberto Lerario, Serena Bonfiglio, MariaPia Sormani, Andrea Tettamanti, Sarah Marktel, Sara Napolitano, Stefano Previtali, Marina Scarlato, MariaGrazia Natali-Sora, Eugenio Mercuri, Nereo Bresolin, Tiziana Mongini, Giancarlo Comi, Roberto Gatti, Fabio Ciceri, Giulio Cossu…
    Citation: BMC Neurology 2012 12:91
  33. Central post-stroke pain (CPSP) is a neuropathic pain syndrome associated with somatosensory abnormalities due to central nervous system lesion following a cerebrovascular insult. Post-stroke pain (PSP) refers...

    Authors: Rogério Adas Ayres de Oliveira, Daniel Ciampi de Andrade, André Guelman Gomes Machado and Manoel Jacobsen Teixeira
    Citation: BMC Neurology 2012 12:89
  34. Stroke is the second most common cause of mortality and the leading cause of neurological disability, cognitive impairment and dementia worldwide. Nimodipine is a dihydropyridinic calcium antagonist with a rol...

    Authors: Penglian Wang, Yongjun Wang, Tao Feng, Xingquan Zhao, Yong Zhou, Yilong Wang, Weixiong Shi and Yi Ju
    Citation: BMC Neurology 2012 12:88
  35. Human cytomegalovirus (CMV) is an ubiquitous pathogen capable of modulating the host immune system. Immune dysfunction is common during CMV infection and includes autoimmune phenomena. Here we focus on a case ...

    Authors: Xinling Xu, Peter Bergman, Thomas Willows, Charlotte Tammik, Marie Sund, Tomas Hökfelt, Cecilia Söderberg-Naucler and Stefania Varani
    Citation: BMC Neurology 2012 12:87
  36. This article describes the rationale and design of a population-based survey of dementia in Valladolid (northwestern Spain). The main aim of the study was to assess the epidemiology of dementia and its subtype...

    Authors: Miguel Angel Tola-Arribas, María José Garea, María Isabel Yugueros, Fernando Ortega-Valín, Ana Cerón, Beatriz Fernández-Malvido, Marta González-Touya, Antonio San José, Ana Botrán, Vanessa Iglesias and Bárbara Díaz-Gómez
    Citation: BMC Neurology 2012 12:86
  37. Clinical and experimental studies have demonstrated that seizures can cause molecular and cellular responses resulting in neuronal damage. At present, there are no valid tests for assessing organic damage to t...

    Authors: Stefania Mondello, Johanna Palmio, Jackson Streeter, Ronald L Hayes, Jukka Peltola and Andreas Jeromin
    Citation: BMC Neurology 2012 12:85
  38. Prophylaxis to prevent relapses in the central nervous system after childhood acute lymphoblastic leukemia (ALL) used to consist of both intrathecal chemotherapy (CT) and cranial irradiation (CRT). CRT was mos...

    Authors: Marita Daams, Ilse Schuitema, Bob W van Dijk, Eline van Dulmen-den Broeder, Anjo JP Veerman, Cor van den Bos and Leo MJ de Sonneville
    Citation: BMC Neurology 2012 12:84
  39. To test the hypothesis that white matter lesions (WML) are primarily associated with regional frontal cortical volumes, and to determine the mediating effects of these regional frontal cortices on the associat...

    Authors: Jun-Young Lee, Philip Insel, R Scott Mackin, Norbert Schuff, Helena Chui, Charles DeCarli, Kee Hyung Park, Susanne G Mueller and Michael W Weiner
    Citation: BMC Neurology 2012 12:83
  40. Neuroprotective strategies after cardiopulmonary resuscitation are currently the focus of experimental and clinical research. Levosimendan has been proposed as a promising drug candidate because of its cardiop...

    Authors: Anna B Roehl, Norbert Zoremba, Markus Kipp, Johannes Schiefer, Andreas Goetzenich, Christian Bleilevens, Nikolaus Kuehn-Velten, Rene Tolba, Rolf Rossaint and Marc Hein
    Citation: BMC Neurology 2012 12:81
  41. The prognostic value of evoked potentials (EPs) in multiple sclerosis (MS) has not been fully established. The correlations between the Expanded Disability Status Scale (EDSS) at First Neurological Evaluation ...

    Authors: Nicolò Margaritella, Laura Mendozzi, Massimo Garegnani, Raffaello Nemni, Elena Colicino, Elisabetta Gilardi and Luigi Pugnetti
    Citation: BMC Neurology 2012 12:80
  42. Vertebral artery dissection (VAD) is often associated with trauma or occurs spontaneously, inevitably causing some neurological deficits. Even though acute infection can be related to the development of sponta...

    Authors: Xudong Pan, Aijun Ma, Kun Wang, Shumin Nie and Mei Wu
    Citation: BMC Neurology 2012 12:79
  43. CADASIL is an autosomal dominant genetic leukoencephalopathy linked to mutations in the Notch3 gene. In rare cases, widespread brain lesions on T2 MRI mimicking multiple sclerosis are observed. From a national re...

    Authors: Nicolas Collongues, Nathalie Derache, Frédéric Blanc, Pierre Labauge, Jérôme de Seze and Gilles Defer
    Citation: BMC Neurology 2012 12:78

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