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  1. In clinical neurology, a comprehensive understanding of consciousness has been regarded as an abstract concept - best left to philosophers. However, times are changing and the need to clinically assess conscio...

    Authors: Jodie R Gawryluk, Ryan CN D'Arcy, John F Connolly and Donald F Weaver
    Citation: BMC Neurology 2010 10:11
  2. Cyclic vomiting syndrome (CVS), which is defined by recurrent stereotypical episodes of nausea and vomiting, is a relatively-common disabling condition that is associated with migraine headache and mitochondri...

    Authors: Richard G Boles, Mary R Lovett-Barr, Amy Preston, B UK Li and Kathleen Adams
    Citation: BMC Neurology 2010 10:10
  3. In idiopathic Parkinson's disease (IPD) transcranial sonography (TCS) represents an alternative diagnostic method to verify clinical diagnosis. Although the phenomenon of an increased echogenicity of the Subst...

    Authors: Sabine Mehnert, Iris Reuter, Karsten Schepp, Peter Maaser, Erwin Stolz and Manfred Kaps
    Citation: BMC Neurology 2010 10:9
  4. Postpoliomyelitis Syndrome (PPS) is a complex of late onset neuromuscular symptoms with new or increased muscle weakness and muscle fatigability as key symptoms. Main clinical complaints are severe fatigue, de...

    Authors: Fieke S Koopman, Anita Beelen, Karin H Gerrits, Gijs Bleijenberg, Tineke A Abma, Marianne de Visser and Frans Nollet
    Citation: BMC Neurology 2010 10:8
  5. Migraine is a common disorder that is highly co-morbid with psychopathological conditions such as depression and anxiety. Despite the extensive research and availability of treatment, migraine remains under-re...

    Authors: Zainab Samaan, E Anne MacGregor, Dowson Andrew, Peter McGuffin and Anne Farmer
    Citation: BMC Neurology 2010 10:7
  6. Previous epidemiologic studies have examined the association of smoking with amyotrophic lateral sclerosis (ALS) incidence, but their results have been inconsistent. Moreover, limited information exists on the...

    Authors: Alvaro Alonso, Giancarlo Logroscino, Susan S Jick and Miguel A Hernán
    Citation: BMC Neurology 2010 10:6
  7. Surrogate pain models have been extensively tested in Normal Human Volunteers (NHV). There are few studies that examined pain models in chronic pain patients. Patients are likely to have altered pain mechanism...

    Authors: Remigiusz Lecybyl, Juan Acosta, Joydeep Ghoshdastidar, Kinga Stringfellow and Magdi Hanna
    Citation: BMC Neurology 2010 10:5
  8. Congenital hemiplegia is the most common form of cerebral palsy (CP) accounting for 1 in 1300 live births. These children have limitations in capacity to use the impaired upper limb and bimanual coordination d...

    Authors: Roslyn Boyd, Leanne Sakzewski, Jenny Ziviani, David F Abbott, Radwa Badawy, Rose Gilmore, Kerry Provan, Jacques-Donald Tournier, Richard AL Macdonell and Graeme D Jackson
    Citation: BMC Neurology 2010 10:4
  9. More than 60% of new strokes each year are "mild" in severity and this proportion is expected to rise in the years to come. Within our current health care system those with "mild" stroke are typically discharg...

    Authors: Annie Rochette, Nicol Korner-Bitensky, Duane Bishop, Robert Teasell, Carole White, Gina Bravo, Robert Côté, Jean Lachaine, Teri Green, Louise-Hélène Lebrun, Sylvain Lanthier, Moira Kapral and Sharon Wood-Dauphinee
    Citation: BMC Neurology 2010 10:3
  10. Because of the emerging intersections of HIV infection and Alzheimer's disease, we examined cerebrospinal fluid (CSF) biomarkers related of amyloid and tau metabolism in HIV-infected patients.

    Authors: Magnus Gisslén, Jan Krut, Ulf Andreasson, Kaj Blennow, Paola Cinque, Bruce J Brew, Serena Spudich, Lars Hagberg, Lars Rosengren, Richard W Price and Henrik Zetterberg
    Citation: BMC Neurology 2009 9:63
  11. Tetrabenazine (TBZ) selectively depletes central monoamines by reversibly binding to the type-2 vesicular monoamine transporter. A previous double blind study in Huntington disease (HD) demonstrated that TBZ e...

    Authors: Samuel Frank
    Citation: BMC Neurology 2009 9:62

    The Erratum to this article has been published in BMC Neurology 2011 11:18

  12. The mismatch between diffusion weighted imaging (DWI) lesion and perfusion imaging (PI) deficit volumes has been used as a surrogate of ischemic penumbra. This pathophysiology-orientated patient selection crit...

    Authors: Benjamin Hotter, Sandra Pittl, Martin Ebinger, Gabriele Oepen, Kati Jegzentis, Kohsuke Kudo, Michal Rozanski, Wolf U Schmidt, Peter Brunecker, Chao Xu, Peter Martus, Matthias Endres, Gerhard J Jungehülsing, Arno Villringer and Jochen B Fiebach
    Citation: BMC Neurology 2009 9:60
  13. The burden of cerebrovascular disease in developing countries is rising sharply. The prevalence of established risk factors of stroke is exceptionally high in Pakistan. However, there is limited data on the bu...

    Authors: Ayeesha Kamran Kamal, Ahmed Itrat, Muhammed Murtaza, Maria Khan, Asif Rasheed, Amin Ali, Amna Akber, Zainab Akber, Naved Iqbal, Sana Shoukat, Farzin Majeed and Danish Saleheen
    Citation: BMC Neurology 2009 9:58
  14. About 80% of all stroke survivors have an upper limb paresis immediately after stroke, only about a third of whom (30 to 40%) regain some dexterity within six months following conventional treatment programs. ...

    Authors: A (Lex) EQ van Delden, C (Lieke) E Peper, Jaap Harlaar, Andreas Daffertshofer, Nienke I Zijp, Kirsten Nienhuys, Peter Koppe, Gert Kwakkel and Peter J Beek
    Citation: BMC Neurology 2009 9:57
  15. Neuromyelitis optica (NMO) is an idiopathic, severe, inflammatory demyelinating disease of the central nervous system, that causes severe optic neuritis and myelitis attacks. Early discrimination between multi...

    Authors: Zeljka Petelin Gadze, Sanja Hajnsek, Silvio Basic, Davor Sporis, Goran Pavlisa and Sibila Nankovic
    Citation: BMC Neurology 2009 9:56
  16. This study describes the prevalence of dementia and major dementia subtypes in Spanish elderly.

    Authors: Jesús de Pedro-Cuesta, Javier Virués-Ortega, Saturio Vega, Manuel Seijo-Martínez, Pedro Saz, Fernanda Rodríguez, Angel Rodríguez-Laso, Ramón Reñé, Susana Pérez de las Heras, Raimundo Mateos, Pablo Martínez-Martín, José María Manubens, Ignacio Mahillo-Fernandez, Secundino López-Pousa, Antonio Lobo, Jordi Llinàs Reglà…
    Citation: BMC Neurology 2009 9:55
  17. Neutralizing antibodies (NAbs) against Interferon beta (IFNβ) are reported to be associated with poor clinical response to therapy in multiple sclerosis (MS) patients. We aimed to quantify the contribution of ...

    Authors: Emilia Sbardella, Valentina Tomassini, Claudio Gasperini, Francesca Bellomi, Luca Ausili Cefaro, Vincenzo Brescia Morra, Guido Antonelli and Carlo Pozzilli
    Citation: BMC Neurology 2009 9:54
  18. This study aimed to explore the value of extended motor nerve conduction studies in patients with ulnar nerve entrapment at the elbow (UNE) in order to find the most sensitive and least time-consuming method. ...

    Authors: Kari Todnem, Ralf Peter Michler, Tony Eugen Wader, Morten Engstrøm and Trond Sand
    Citation: BMC Neurology 2009 9:52
  19. Apart from promoting physical recovery and assisting in activities of daily living, a major challenge in stroke rehabilitation is to minimize psychosocial morbidity and to promote the reintegration of stroke s...

    Authors: Janita PC Chau, David R Thompson, Sheila Twinn, Anne M Chang and Jean Woo
    Citation: BMC Neurology 2009 9:49
  20. 1) To report site-specific normative values by age, sex and educational level for four components of the 10/66 Dementia Research Group cognitive test battery; 2) to estimate the main and interactive effects of...

    Authors: Ana Luisa Sosa, Emiliano Albanese, Martin Prince, Daisy Acosta, Cleusa P Ferri, Mariella Guerra, Yueqin Huang, KS Jacob, Juan Llibre de Rodriguez, Aquiles Salas, Fang Yang, Ciro Gaona, AT Joteeshwaran, Guillermina Rodriguez, Gabriela Rojas de la Torre, Joseph D Williams…
    Citation: BMC Neurology 2009 9:48
  21. The number of individuals at risk for dementia will probably increase in ageing societies as will the array of preventive and therapeutic options, both however within limited economic resources. For economic a...

    Authors: Matthias W Riepe, Thomas Mittendorf, Hans Förstl, Lutz Frölich, Martin Haupt, Reiner Leidl, Christoph Vauth and Matthias Graf von der Schulenburg
    Citation: BMC Neurology 2009 9:47
  22. Pharmacological high-throughput screening (HTS) represents a powerful strategy for drug discovery in genetic diseases, particularly when the full spectrum of pathological dysfunctions remains unclear, such as ...

    Authors: Nadège Calmels, Hervé Seznec, Pascal Villa, Laurence Reutenauer, Marcel Hibert, Jacques Haiech, Pierre Rustin, Michel Koenig and Hélène Puccio
    Citation: BMC Neurology 2009 9:46
  23. Multiple Sclerosis (MS) is an incurable, chronic, potentially progressive and unpredictable disease of the central nervous system. The disease produces a range of unpleasant and debilitating symptoms, which ca...

    Authors: Rona Moss-Morris, Laura Dennison, Lucy Yardley, Sabine Landau, Suzanne Roche, Paul McCrone and Trudie Chalder
    Citation: BMC Neurology 2009 9:45
  24. No large study has compared the yield of diffusion-weighted imaging (DWI) with clinical examination in order to differentiate lacunar stroke from other stroke subtypes. This differentiation is important for gu...

    Authors: Halvor Naess, Jan C Brogger Jr, Titto Idicula, Ulrike Waje-Andreassen, Gunnar Moen and Lars Thomassen
    Citation: BMC Neurology 2009 9:44
  25. Most patients who suffer a stroke experience reduced walking competency and health-related quality of life (HRQoL). A key factor in effective stroke rehabilitation is intensive, task-specific training. Recent ...

    Authors: Ingrid GL van de Port, Lotte Wevers, Hanneke Roelse, Lenneke van Kats, Eline Lindeman and Gert Kwakkel
    Citation: BMC Neurology 2009 9:43
  26. Older adults with cognitive problems have a higher risk of falls, at least twice that of cognitively normal older adults. The consequences of falls in this population are very serious: fallers with cognitive p...

    Authors: Manuel Montero-Odasso, Jennie L Wells, Michael J Borrie and Mark Speechley
    Citation: BMC Neurology 2009 9:42
  27. The aim of this study was to evaluate the diagnostic accuracy of positron emission tomography (PET) using F18 fluorodeoxyglucose (FDG) in the differential diagnosis of early-onset Alzheimer's disease (AD) and oth...

    Authors: Peter K Panegyres, Jeffrey M Rogers, Michael McCarthy, Andrew Campbell and Jing Shan Wu
    Citation: BMC Neurology 2009 9:41
  28. Cervical artery dissection is a leading cause of cerebral ischemia in young adults. Morphological investigations have shown alterations in the extracellular matrix (ECM) of affected vessel walls. As matrix met...

    Authors: Armin Buss, Katrin Pech, Susanne Roelver, Brunhilde Bloemeke, Christoph Klotzsch and Sebastian Breuer
    Citation: BMC Neurology 2009 9:40
  29. Hemifacial atrophy (Parry-Romberg syndrome) is a relatively rare disease. The etiology of the disease is not clear. Some authors postulate its relation with limited scleroderma linearis. Linear scleroderma "en...

    Authors: Beata Bergler-Czop, Anna Lis-Święty and Ligia Brzezińska-Wcisło
    Citation: BMC Neurology 2009 9:39
  30. Stroke is the most common disabling neurological condition in adults. Falls and poor mobility are major contributors to stroke-related disability. Falls are more frequent and more likely to result in injury am...

    Authors: Catherine M Dean, Chris Rissel, Michelle Sharkey, Catherine Sherrington, Robert G Cumming, Ruth N Barker, Stephen R Lord, Sandra D O'Rourke and Catherine Kirkham
    Citation: BMC Neurology 2009 9:38
  31. Cerebral ischemia involves a series of reactions which ultimately influence the final volume of a brain infarction. We hypothesize that polymorphisms in genes encoding proteins involved in these reactions coul...

    Authors: Leema Reddy Peddareddygari, Ana Virginia Dutra, Mark A Levenstien, Souvik Sen and Raji P Grewal
    Citation: BMC Neurology 2009 9:37
  32. Carotid angioplasty with stenting is a relatively new, increasingly used, less-invasive treatment for the treatment of symptomatic carotid artery stenosis. It is being evaluated in ongoing and nearly finished ...

    Authors: Paul J Nederkoorn and Martin M Brown
    Citation: BMC Neurology 2009 9:36
  33. Previously published studies have reported that up to 43% of patients with disorders of consciousness are erroneously assigned a diagnosis of vegetative state (VS). However, no recent studies have investigated...

    Authors: Caroline Schnakers, Audrey Vanhaudenhuyse, Joseph Giacino, Manfredi Ventura, Melanie Boly, Steve Majerus, Gustave Moonen and Steven Laureys
    Citation: BMC Neurology 2009 9:35
  34. People with Multiple Sclerosis have a life long need for physiotherapy and exercise interventions due to the progressive nature of the disease and their greater risk of the complications of inactivity. The Mul...

    Authors: Susan Coote, Maria Garrett, Neasa Hogan, Aidan Larkin and Jean Saunders
    Citation: BMC Neurology 2009 9:34
  35. Although chemotherapy with procarbazine, lomustine and vincristine (PCV) is considered to be well tolerated, side effects frequently lead to dose reduction or even discontinuation of treatment of oligodendrogl...

    Authors: J Vesper, E Graf, C Wille, J Tilgner, M Trippel, G Nikkhah and CB Ostertag
    Citation: BMC Neurology 2009 9:33
  36. A major class of axon growth-repulsive molecules associated with CNS scar tissue is the family of chondroitin sulphate proteoglycans (CSPGs). Experimental spinal cord injury (SCI) has demonstrated rapid re-exp...

    Authors: Armin Buss, Katrin Pech, Byron A Kakulas, Didier Martin, Jean Schoenen, Johannes Noth and Gary A Brook
    Citation: BMC Neurology 2009 9:32
  37. Intracranial stenosis is the most common cause of stroke among Asians. It has a poor prognosis with a high rate of recurrence. No effective medical or surgical treatment modality has been developed for the tre...

    Authors: Ayeesha Kamran Kamal, Fawad Taj, Babar Junaidi, Asif Rasheed, Moazzam Zaidi, Muhammed Murtaza, Naved Iqbal, Fahad Hashmat, Syed Vaqas Alam, Uzma Saleem, Shahan Waheed, Lajpat Bansari, Nabi Shah, Maria Samuel, Madiha Yameen, Sobia Naz…
    Citation: BMC Neurology 2009 9:31
  38. Little is known about clinical features and prognosis of patients with ischaemic stroke caused by infarction in the territory of the anterior cerebral artery (ACA). This single centre, retrospective study was ...

    Authors: Adrià Arboix, Luis García-Eroles, Núria Sellarés, Agnès Raga, Montserrat Oliveres and Joan Massons
    Citation: BMC Neurology 2009 9:30
  39. Co-morbidities of vertiginous diseases have so far not been investigated systematically. Thus, it is still unclear whether the different vertigo syndromes (e.g. benign paroxysmal positional vertigo (BPPV), Men...

    Authors: Jan C Warninghoff, Otmar Bayer, Uta Ferrari and Andreas Straube
    Citation: BMC Neurology 2009 9:29
  40. The extended tau haplotype (H1) that covers the entire human microtubule-associated protein tau (MAPT) gene has been implicated in Parkinson's disease (PD). Nevertheless, controversial results, such as two studie...

    Authors: Nikolaos Refenes, Juliane Bolbrinker, Georgios Tagaris, Antonio Orlacchio, Nikolaos Drakoulis and Reinhold Kreutz
    Citation: BMC Neurology 2009 9:26

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