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  1. Frontotemporal lobar degeneration with ubiquitin and TDP-43 positive neuronal inclusions represents a novel entity (FTLD-TDP) that may be associated with motor neuron disease (FTLD-MND); involvement of extrapy...

    Authors: Robert Rusina, Gabor G Kovacs, Jindřich Fiala, Jakub Hort, Petr Ridzoň, Iva Holmerová, Thomas Ströbel and Radoslav Matěj
    Citation: BMC Neurology 2011 11:50
    Content type: Case report Published on:

  2. Traditional magnetic resonance (MR) imaging can identify abnormal changes in ipsilateral thalamus in patients with unilateral middle cerebral artery (MCA) infarcts. However, it is difficult to demonstrate thes...

    Authors: Chuo Li, Xueying Ling, Sirun Liu, Anding Xu, Yusheng Zhang, Shihui Xing, Zhong Pei and Jinsheng Zeng
    Citation: BMC Neurology 2011 11:49
    Content type: Research article Published on:

  3. Because of the subjective nature of Restless Legs Syndrome (RLS) symptoms and the impact of these symptoms on sleep, patient-reported outcomes (PROs) play a prominent role as study endpoints in clinical trials...

    Authors: Daniel M Canafax, Abhijeet Bhanegaonkar, Murtuza Bharmal and Michael Calloway
    Citation: BMC Neurology 2011 11:48
    Content type: Research article Published on:

  4. Guidelines recommend maintaining the heart rate (HR) of acute stroke patients within physiological limits; data on the frequency and predictors of significant deviations from these limits are scarce.

    Authors: Martin A Ritter, Anne Rohde, Peter U Heuschmann, Rainer Dziewas, Jörg Stypmann, Darius G Nabavi and Bernd E Ringelstein
    Citation: BMC Neurology 2011 11:47
    Content type: Research article Published on:

  5. Patients with acquired brain damage (ABD) have suffered a brain lesion that interrupts vital development in the physical, psychological and social spheres. Stroke and traumatic brain injury (TBI) are the two m...

    Authors: Javier Mar, Arantzazu Arrospide, José María Begiristain, Isabel Larrañaga, Elena Elosegui and Juan Oliva-Moreno
    Citation: BMC Neurology 2011 11:46
    Content type: Research article Published on:

  8. Pain in general and headache in particular are characterized by a change in activity in brain areas involved in pain processing. The therapeutic challenge is to identify drugs with molecular targets that resto...

    Authors: Andreas Straube, Bernhard Aicher, Bernd L Fiebich and Gunther Haag
    Citation: BMC Neurology 2011 11:43
    Content type: Review Published on:

  9. Annually, 41,000 people in the Netherlands have strokes. This has multiple physical and psychosocial consequences. Most patients return home after discharge from hospital. Quality aftercare by general practiti...

    Authors: Leonie de Weerd, Wijnand AF Rutgers, Klaas H Groenier and Klaas van der Meer
    Citation: BMC Neurology 2011 11:42
    Content type: Research article Published on:

  11. Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, for which no definitive treatment is available. Most patients start with a relapsing-remitting course (RRM...

    Authors: Peter J Jongen, Gerald Hengstman, Raymond Hupperts, Hans Schrijver, Job Gilhuis, Joseph H Vliegen, Erwin Hoogervorst, Marc van Huizen, Eric van Munster, Johnny Samijn, Els de Schryver, Theodora Siepman, Martijn Tonk, Eveline Zandbergen, Jacques ten Holter, Ruud van der Kruijk…
    Citation: BMC Neurology 2011 11:40
    Content type: Study protocol Published on:

  12. Although free radicals have been reported to play a role in the expansion of ischemic brain lesions, the effect of free radical scavengers is still under debate. In this study, the temporal profile of ischemic...

    Authors: Taizen Nakase, Shotaroh Yoshioka and Akifumi Suzuki
    Citation: BMC Neurology 2011 11:39
    Content type: Research article Published on:

  13. To examine age and sex specific incidence and 30 day case fatality for subarachnoid haemorrhage (SAH) in Scotland over a 20 year period.

    Authors: Karen J Macpherson, James D Lewsey, Pardeep S Jhund, Michelle Gillies, Jim WT Chalmers, Adam Redpath, Andrew Briggs, Matthew Walters, Peter Langhorne, Simon Capewell, John JV McMurray and Kate MacIntyre
    Citation: BMC Neurology 2011 11:38
    Content type: Research article Published on:

  15. Spinal muscular atrophy (SMA) is an autosomal recessive disorder that affects the motoneurons of the spinal anterior horn, resulting in hypotonia and muscle weakness. The disease is caused by deletion or mutat...

    Authors: Illora A Darbar, Paulo G Plaggert, Maria Bernadete D Resende, Edmar Zanoteli and Umbertina C Reed
    Citation: BMC Neurology 2011 11:36
    Content type: Research article Published on:

  16. In idiopathic Parkinson's disease (PD) the clinical features are heterogeneous and include different predominant symptoms. The aim of the present study was to determine the relationship between subregional aro...

    Authors: Sayaka Asari, Ken-ichi Fujimoto, Akihiro Miyauchi, Toshihiko Sato, Imaharu Nakano and Shin-ichi Muramatsu
    Citation: BMC Neurology 2011 11:35
    Content type: Research article Published on:

  17. Dysphagia is a major complication in hemispheric as well as brainstem stroke patients causing aspiration pneumonia and increased mortality. Little is known about the recovery from dysphagia after stroke. The a...

    Authors: Inga K Teismann, Sonja Suntrup, Tobias Warnecke, Olaf Steinsträter, Maren Fischer, Agnes Flöel, E Bernd Ringelstein, Christo Pantev and Rainer Dziewas
    Citation: BMC Neurology 2011 11:34
    Content type: Research article Published on:

  18. The potential effect of age-related factors on health-related quality of life (HRQOL) of patients with epilepsy has rarely been analyzed in the literature.

    Authors: Valeria Edefonti, Francesca Bravi, Katherine Turner, Ettore Beghi, Maria Paola Canevini, Monica Ferraroni and Ada Piazzini
    Citation: BMC Neurology 2011 11:33
    Content type: Research article Published on:

  19. The available health resources limit the amount of therapy that may be offered to children with cerebral palsy and the amount of training in each session may be insufficient to drive the neuroplastic changes, ...

    Authors: Peder E Bilde, Mette Kliim-Due, Betina Rasmussen, Line Z Petersen, Tue H Petersen and Jens B Nielsen
    Citation: BMC Neurology 2011 11:32
    Content type: Research article Published on:

  20. Celiac disease (CD) is a common systemic disease related to a permanent intolerance to gluten and is often associated with different autoimmune and neurological diseases. Its mean prevalence in the general pop...

    Authors: Luis Rodrigo, Carlos Hernández-Lahoz, Dolores Fuentes, Noemí Alvarez, Antonio López-Vázquez and Segundo González
    Citation: BMC Neurology 2011 11:31
    Content type: Research article Published on:

  21. Headaches are more frequent in Chronic Fatigue Syndrome (CFS) than healthy control (HC) subjects. The 2004 International Headache Society (IHS) criteria were used to define CFS headache phenotypes.

    Authors: Murugan K Ravindran, Yin Zheng, Christian Timbol, Samantha J Merck and James N Baraniuk
    Citation: BMC Neurology 2011 11:30
    Content type: Research article Published on:

  22. Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans of elderly people and is related to vascular risk factors and cognitive and motor impairment, ultimately leading to dementia or par...

    Authors: Anouk GW van Norden, Karlijn F de Laat, Rob AR Gons, Inge WM van Uden, Ewoud J van Dijk, Lucas JB van Oudheusden, Rianne AJ Esselink, Bastiaan R Bloem, Baziel GM van Engelen, Machiel J Zwarts, Indira Tendolkar, Marcel G Olde-Rikkert, Maureen J van der Vlugt, Marcel P Zwiers, David G Norris and Frank-Erik de Leeuw
    Citation: BMC Neurology 2011 11:29
    Content type: Study protocol Published on:

  23. Restless legs syndrome (RLS) is a neurological disorder with a lifetime prevalence of 3-10%. in European studies. However, the diagnosis of RLS in primary care remains low and mistreatment is common.

    Authors: Diego Garcia-Borreguero, Paul Stillman, Heike Benes, Heiner Buschmann, K Ray Chaudhuri, Victor M Gonzalez Rodríguez, Birgit Högl, Ralf Kohnen, Giorgio Carlo Monti, Karin Stiasny-Kolster, Claudia Trenkwalder, Anne-Marie Williams and Marco Zucconi
    Citation: BMC Neurology 2011 11:28
    Content type: Research article Published on:

  24. Many individuals diagnosed with Multiple Sclerosis (MS) are sensitive to increased body temperature, which has been recognized as correlating with the symptom of fatigue. The need to explore this association h...

    Authors: Gullvi Flensner, Anna-Christina Ek, Olle Söderhamn and Anne-Marie Landtblom
    Citation: BMC Neurology 2011 11:27
    Content type: Research article Published on:

  25. In daily clinical setting, some patients affected by relapsing-remitting Multiple Sclerosis (RRMS) are switched from the low-dose to the high-dose Interferon beta (IFNB) in order to achieve a better control of...

    Authors: Luca Prosperini, Giovanna Borriello, Laura De Giglio, Laura Leonardi, Valeria Barletta and Carlo Pozzilli
    Citation: BMC Neurology 2011 11:26
    Content type: Research article Published on:

  26. Occipital nerve stimulation (ONS) has raised new hope for drug-resistant chronic cluster headache (drCCH), a devastating condition. However its mode of action remains elusive. Since the long delay to meaningfu...

    Authors: Delphine Magis, Marie-Aurélie Bruno, Arnaud Fumal, Pierre-Yves Gérardy, Roland Hustinx, Steven Laureys and Jean Schoenen
    Citation: BMC Neurology 2011 11:25
    Content type: Research article Published on:

  27. Memory is one of the most impaired functions after traumatic brain injury (TBI). We used diffusion tensor imaging (DTI) to determine the structural basis of memory deficit. We correlated fractional anisotropy ...

    Authors: Eva M Palacios, Davinia Fernandez-Espejo, Carme Junque, Rocio Sanchez-Carrion, Teresa Roig, Jose M Tormos, Nuria Bargallo and Pere Vendrell
    Citation: BMC Neurology 2011 11:24
    Content type: Research article Published on:

  28. Chronic Fatigue Syndrome (CFS) is increasingly recognized as a cause of disability and inactivity in adolescents in the Netherlands. CFS is characterized by unexplained fatigue lasting more than 6 months. Cogn...

    Authors: Sanne L Nijhof, Gijs Bleijenberg, Cuno SPM Uiterwaal, Jan LL Kimpen and Elise M van de Putte
    Citation: BMC Neurology 2011 11:23
    Content type: Study protocol Published on:

  29. Large-artery intracranial atherosclerosis may be the most frequent cause of ischemic stroke worldwide. Traditional approaches have attempted to target the disease when it is already symptomatic. However, early...

    Authors: Elena López-Cancio, Laura Dorado, Mónica Millán, Silvia Reverté, Anna Suñol, Anna Massuet, María Mataró, Amparo Galán, Maite Alzamora, Guillem Pera, Pere Torán, Antoni Dávalos and Juan F Arenillas
    Citation: BMC Neurology 2011 11:22
    Content type: Study protocol Published on:

  30. Of the estimated 5.3 million people with Alzheimer's disease in the United States, more than half would be classified as having moderate or severe disease. Alzheimer's disease is a progressive disorder with th...

    Authors: Marwan Sabbagh and Jeffrey Cummings
    Citation: BMC Neurology 2011 11:21
    Content type: Review Published on:

  31. Various functional resonance imaging, magnetoencephalographic and lesion studies suggest the involvement of the insular cortex in the control of swallowing. However, the exact location of insular activation du...

    Authors: Peter Sörös, Faisal Al-Otaibi, Savio WH Wong, J Kevin Shoemaker, Seyed M Mirsattari, Vladimir Hachinski and Ruth E Martin
    Citation: BMC Neurology 2011 11:20
    Content type: Case report Published on:

  32. Authors: Jessica M Nielsen, Christoph Pohl, Chris H Polman, Frederik Barkhof, Mark S Freedman, Gilles Edan, David H Miller, Lars Bauer, Rupert Sandbrink, Ludwig Kappos and Bernard MJ Uitdehaag
    Citation: BMC Neurology 2011 11:19
    Content type: Erratum Published on:

    The original article was published in BMC Neurology 2009 9:19

  34. Nearly half of all patients diagnosed with multiple sclerosis (MS) will develop cognitive dysfunction. Studies highlighted from no/weak impact to a strong impact of cognitive impairment on quality of life (QoL...

    Authors: Karine Baumstarck-Barrau, Marie-Claude Simeoni, Françoise Reuter, Irina Klemina, Valérie Aghababian, Jean Pelletier and Pascal Auquier
    Citation: BMC Neurology 2011 11:17
    Content type: Research article Published on:

  35. We aimed to examine current practice of the management and secondary prevention of intracerebral haemorrhage (ICH) in China where the disease is more common than in Western populations.

    Authors: Jade W Wei, Yining Huang, Ji-Guang Wang, Ming Liu, Lawrence KS Wong, Qifang Huang, Li'e Wu, Emma L Heeley, Hisatomi Arima and Craig S Anderson
    Citation: BMC Neurology 2011 11:16
    Content type: Research article Published on:

  36. The major difficulty in postoperative care in patients after craniotomy is to distinguish the intracranial deficits from the residual effect of general anesthesia. In present study, we used cerebral state inde...

    Authors: Ming Xu, Yan-Ni Lei and Jian-Xin Zhou
    Citation: BMC Neurology 2011 11:15
    Content type: Research article Published on:

  37. Stroke is a major cause of death and leading cause of disability in the United States. To maximize a stroke patient's chances of receiving thrombolytic treatment for acute ischemic stroke, it is important to i...

    Authors: Prasanthi Govindarajan, David Ghilarducci, Charles McCulloch, Jessica Pierog, Evan Bloom and Claiborne Johnston
    Citation: BMC Neurology 2011 11:14
    Content type: Study protocol Published on:

  38. The clinical presentation in progressive supranuclear palsy (PSP), an atypical parkinsonian disorder, includes varying degrees of frontal dysexecutive symptoms. Using diffusion tensor imaging (DTI) and tractog...

    Authors: Pia Kvickström, Bengt Eriksson, Danielle van Westen, Jimmy Lätt, Christina Elfgren and Christer Nilsson
    Citation: BMC Neurology 2011 11:13
    Content type: Research article Published on:

  39. Acute/subacute cerebral infarction (ASCI) in HIV-negative cryptococcal meningoencephalitis (CM) adults has rarely been examined by a series of MRI-based follow-up study. We studied a series of MRI follow-up st...

    Authors: Shu-Fang Chen, Cheng-Hsien Lu, Chun-Chung Lui, Chi-Ren Huang, Yao-Chung Chuang, Teng-Yeow Tan, Nai-Wen Tsai, Chiung-Chih Chang, Wan-Chen Tsai and Wen-Neng Chang
    Citation: BMC Neurology 2011 11:12
    Content type: Research article Published on:

  41. Epilepsy is a neurological disorder, characterized by recurrent unprovoked seizures which have a high impact on the individual as well as on society as a whole. In addition to the economic burden, epilepsy imp...

    Authors: Reina JA de Kinderen, Danielle AJE Lambrechts, Debby Postulart, Alfons GH Kessels, Jos GM Hendriksen, Albert P Aldenkamp, Silvia MAA Evers and Marian HJM Majoie
    Citation: BMC Neurology 2011 11:10
    Content type: Study protocol Published on:

  42. Schwannomatosis is a disease characterized by multiple non-vestibular schwannomas. Although biallelic NF2 mutations are found in schwannomas, no germ line event is detected in schwannomatosis patients. In contras...

    Authors: Guillaume Rousseau, Tetsuro Noguchi, Violaine Bourdon, Hagay Sobol and Sylviane Olschwang
    Citation: BMC Neurology 2011 11:9
    Content type: Research article Published on:

  44. Neuropathic pain (NeP) is a common symptom of a group of a variety of conditions, including diabetic neuropathy, trigeminal neuralgia, or postherpetic neuralgia. Prevalence of NeP has been estimated to range b...

    Authors: Ana Navarro, María T Saldaña, Concepción Pérez, Sandra Torrades and Javier Rejas
    Citation: BMC Neurology 2011 11:7
    Content type: Research article Published on:

  45. Stroke is a major cause of dysphagia, but little is known about when and how dysphagic patients should be fed and treated after an acute stroke. The purpose of this study is to establish the feasibility, risks...

    Authors: Hideaki Takahata, Keisuke Tsutsumi, Hiroshi Baba, Izumi Nagata and Masahiro Yonekura
    Citation: BMC Neurology 2011 11:6
    Content type: Research article Published on:

  46. The variations of the circle of Willis (CW) are clinically important as patients with effective collateral circulations have a lower risk of transient ischemic attack and stroke than those with ineffective col...

    Authors: K Ranil D De Silva, Rukmal Silva, Dhammika Amaratunga, WSL Gunasekera and Rohan W Jayesekera
    Citation: BMC Neurology 2011 11:5
    Content type: Research article Published on:

  47. DNA polymerase γ (POLG) is the only known mitochondrial DNA (mtDNA) polymerase. It mediates mtDNA replication and base excision repair. Mutations in the POLG gene lead to reduction of functional mtDNA (mtDNA depl...

    Authors: André Schaller, Dagmar Hahn, Christopher B Jackson, Ilse Kern, Christophe Chardot, Dominique C Belli, Sabina Gallati and Jean-Marc Nuoffer
    Citation: BMC Neurology 2011 11:4
    Content type: Research article Published on:

  48. Epilepsy affects an estimated 50 million people and accounts for approximately 1% of days lost to ill health globally, making it one of the most common, serious neurological disorders. While there are abundant...

    Authors: Maree L Hackett, Nicholas S Glozier, Alexandra L Martiniuk, Stephen Jan and Craig S Anderson
    Citation: BMC Neurology 2011 11:3
    Content type: Study protocol Published on:

  49. Delayed arrival at hospital is one of the major obstacles in enhancing the rate of thrombolysis therapy in patients with acute ischemic stroke. Our study aimed to investigate factors associated with prehospita...

    Authors: Young Seo Kim, Sang-Soon Park, Hee-Joon Bae, A-Hyun Cho, Yong-Jin Cho, Moon-Ku Han, Ji Hoe Heo, Kyusik Kang, Dong-Eog Kim, Hahn Young Kim, Gyeong-Moon Kim, Sun Uk Kwon, Hyung-Min Kwon, Byung-Chul Lee, Kyung Bok Lee, Seung-Hoon Lee…
    Citation: BMC Neurology 2011 11:2
    Content type: Research article Published on:
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BMC Neurology

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