Table 2 Description of the PD family material. Number of affected and unaffected individuals in each family, mean age at onset and range for affected, and mean age and range for unaffected, as of 1997. In narrow definition PD only individuals with probable PD were assigned as affected. In broad definition PD both individuals with probable and possible PD were assigned as affected.
From: A linkage study of candidate loci in familial Parkinson's Disease
| Â | Narrow definition PD | Broad definition PD | Unaffected | ||||||
|---|---|---|---|---|---|---|---|---|---|
Family | N of individuals (total / sampled) | Mean age at onset | Range of age at onset | N of individuals (total / sampled) | Mean age at onset (sampled only) | Range of age at onset (sampled only) | N of unaffected individuals sampled | Mean age | Age range |
1 | 4 / 2 | 65.8 | 58–73 | 9 / 4 | 69.5 | 63–73 | 4 | 76.8 | 72–83 |
2 | 4 / 3 | 67.3 | 49–79 | 6 / 5 | 52.4 | 32–77 | 9 | 49.9 | 24–72 |
3 | 4 / 2 | 55.3 | 44–77 | 8 / 3 | 65.3 | 44–77 | 13 | 56.7 | 29–85 |
4 | 4 / 2 | 54.3 | 48–59 | 6 / 4 | 55.8 | 26–85 | 12 | 53.7 | 27–75 |
5 | 5 / 3 | 63.0 | 48–78 | 16 / 9 | 55.8 | 9–78 | 16 | 56.4 | 41–86 |
6 | 4 / 3 | 24.0 | 8–35 | 16 / 3 | 20.3 | 8–28 | 2 | 29.5 | 16–43 |
7 | 4 / 3 | 65.8 | 40–78 | 14 / 6 | 42.5 | 10–78 | 7 | 67.7 | 48–91 |
8 | 2 / 2 | 49.0 | 15–83 | 6 / 5 | 30.0 | 14–83 | 10 | 43.4 | 23–84 |
9 | 3 / 2 | 59.0 | 46–76 | 9 / 3 | 55.3 | 46–65 | 3 | 55.7 | 47–73 |
10 | 3 / 3 | 62.3 | 54–76 | 9 / 6 | 59.5 | 40–79 | 13 | 51.7 | 30–79 |
11 | 3 / 3 | 58.7 | 39–78 | 6 / 3 | 58.7 | 39–78 | 8 | 56.0 | 46–73 |
12 | 2 / 2 | 66.5 | 66–67 | 2 / 2 | 66.5 | 66–67 | 8 | 68.3 | 63–74 |