Payami H, Zareparsi S: Genetic epidemiology of Parkinson's disease. J Geriatr Psychiatry Neurol. 1998, 11: 98-106.
Article
CAS
PubMed
Google Scholar
Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, Houlden H, Pickering-Brown S, Chakraverty S, Isaacs A, Grover A, et al: Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17. Nature. 1998, 393: 702-705. 10.1038/31508.
Article
CAS
PubMed
Google Scholar
Ichinose H, Ohye T, Takahashi E, Seki N, Hori T, Segawa M, Nomura Y, Endo K, Tanaka H, Tsuji S, et al: Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene. Nat Genet. 1994, 8: 236-242.
Article
CAS
PubMed
Google Scholar
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, et al: Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science. 1997, 276: 2045-2047. 10.1126/science.276.5321.2045.
Article
CAS
PubMed
Google Scholar
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N: Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature. 1998, 392: 605-608. 10.1038/33416.
Article
CAS
PubMed
Google Scholar
Lucking CB, Durr A, Bonifati V, Vaughan J, De Michele G, Gasser T, Harhangi BS, Meco G, Denefle P, Wood NW, et al: Association between early-onset Parkinson's disease and mutations in the parkin gene. French Parkinson's Disease Genetics Study Group. N Engl J Med. 2000, 342: 1560-1567. 10.1056/NEJM200005253422103.
Article
CAS
PubMed
Google Scholar
Leroy E, Boyer R, Auburger G, Leube B, Ulm G, Mezey E, Harta G, Brownstein MJ, Jonnalagada S, Chernova T, et al: The ubiquitin pathway in Parkinson's disease. Nature. 1998, 395: 451-452. 10.1038/26652.
Article
CAS
PubMed
Google Scholar
Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M, et al: Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science. 2003, 299: 256-259. 10.1126/science.1077209.
Article
CAS
PubMed
Google Scholar
Gasser T, Muller-Myhsok B, Wszolek ZK, Oehlmann R, Calne DB, Bonifati V, Bereznai B, Fabrizio E, Vieregge P, Horstmann RD: A susceptibility locus for Parkinson's disease maps to chromosome 2p13. Nat Genet. 1998, 18: 262-265.
Article
CAS
PubMed
Google Scholar
Farrer M, Gwinn-Hardy K, Muenter M, DeVrieze FW, Crook R, Perez-Tur J, Lincoln S, Maraganore D, Adler C, Newman S, et al: A chromosome 4p haplotype segregating with Parkinson's disease and postural tremor. Hum Mol Genet. 1999, 8: 81-85. 10.1093/hmg/8.1.81.
Article
CAS
PubMed
Google Scholar
Valente EM, Bentivoglio AR, Dixon PH, Ferraris A, Ialongo T, Frontali M, Albanese A, Wood NW: Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36. Am J Hum Genet. 2001, 68: 895-900. 10.1086/319522.
Article
CAS
PubMed
PubMed Central
Google Scholar
Hicks AA, Petursson H, Jonsson T, Stefansson H, Johannsdottir HS, Sainz J, Frigge ML, Kong A, Gulcher JR, Stefansson K, et al: A susceptibility gene for late-onset idiopathic Parkinson's disease. Ann Neurol. 2002, 52: 549-555. 10.1002/ana.10324.
Article
CAS
PubMed
Google Scholar
Funayama M, Hasegawa K, Kowa H, Saito M, Tsuji S, Obata F: A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1. Ann Neurol. 2002, 51: 296-301. 10.1002/ana.10113.
Article
CAS
PubMed
Google Scholar
Pankratz N, Nichols WC, Uniacke SK, Halter C, Rudolph A, Shults C, Conneally PM, Foroud T: Significant linkage of Parkinson disease to chromosome 2q36-37. Am J Hum Genet. 2003, 72: 1053-1057. 10.1086/374383.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zareparsi S, Kaye J, Camicioli R, Kramer P, Nutt J, Bird T, Litt M, Payami H, Kay J: Analysis of the alpha-synuclein G209A mutation in familial Parkinson's disease. Lancet. 1998, 351: 37-38.
Article
CAS
PubMed
Google Scholar
Zareparsi S, Wirdefeldt K, Burgess CE, Nutt J, Kramer P, Schalling M, Payami H: Exclusion of dominant mutations within the FTDP-17 locus on chromosome 17 for Parkinson's disease. Neurosci Lett. 1999, 272: 140-142. 10.1016/S0304-3940(99)00581-9.
Article
CAS
PubMed
Google Scholar
Murer MG, Yan Q, Raisman-Vozari R: Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease. Prog Neurobiol. 2001, 63: 71-124. 10.1016/S0301-0082(00)00014-9.
Article
CAS
PubMed
Google Scholar
Saarma M, Sariola H: Other neurotrophic factors: glial cell line-derived neurotrophic factor (GDNF). Microsc Res Tech. 1999, 45: 292-302. 10.1002/(SICI)1097-0029(19990515/01)45:4/5<292::AID-JEMT13>3.3.CO;2-#.
Article
CAS
PubMed
Google Scholar
Frim DM, Uhler TA, Galpern WR, Beal MF, Breakefield XO, Isacson O: Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat. Proc Natl Acad Sci U S A. 1994, 91: 5104-5108.
Article
CAS
PubMed
PubMed Central
Google Scholar
Choi-Lundberg DL, Lin Q, Chang YN, Chiang YL, Hay CM, Mohajeri H, Davidson BL, Bohn MC: Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science. 1997, 275: 838-841. 10.1126/science.275.5301.838.
Article
CAS
PubMed
Google Scholar
Treanor JJ, Goodman L, de Sauvage F, Stone DM, Poulsen KT, Beck CD, Gray C, Armanini MP, Pollock RA, Hefti F, et al: Characterization of a multicomponent receptor for GDNF. Nature. 1996, 382: 80-83. 10.1038/382080a0.
Article
CAS
PubMed
Google Scholar
Amara SG, Kuhar MJ: Neurotransmitter transporters: recent progress. Annu Rev Neurosci. 1993, 16: 73-93. 10.1146/annurev.ne.16.030193.000445.
Article
CAS
PubMed
Google Scholar
Zetterstrom RH, Solomin L, Jansson L, Hoffer BJ, Olson L, Perlmann T: Dopamine neuron agenesis in Nurr1-deficient mice. Science. 1997, 276: 248-250. 10.1126/science.276.5310.248.
Article
CAS
PubMed
Google Scholar
Le WD, Xu P, Jankovic J, Jiang H, Appel SH, Smith RG, Vassilatis DK: Mutations in NR4A2 associated with familial Parkinson disease. Nat Genet. 2003, 33: 85-89. 10.1038/ng1066.
Article
CAS
PubMed
Google Scholar
Engelender S, Kaminsky Z, Guo X, Sharp AH, Amaravi RK, Kleiderlein JJ, Margolis RL, Troncoso JC, Lanahan AA, Worley PF, et al: Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nat Genet. 1999, 22: 110-114. 10.1038/8820.
Article
CAS
PubMed
Google Scholar
Wakabayashi K, Engelender S, Yoshimoto M, Tsuji S, Ross CA, Takahashi H: Synphilin-1 is present in Lewy bodies in Parkinson's disease. Ann Neurol. 2000, 47: 521-523. 10.1002/1531-8249(200004)47:4<521::AID-ANA18>3.3.CO;2-2.
Article
CAS
PubMed
Google Scholar
Hughes AJ, Daniel SE, Kilford L, Lees AJ: Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry. 1992, 55: 181-184.
Article
CAS
PubMed
PubMed Central
Google Scholar
Boehnke M: Estimating the power of a proposed linkage study: a practical computer simulation approach. Am J Hum Genet. 1986, 39: 513-527.
CAS
PubMed
PubMed Central
Google Scholar
National Center for Biotechnology Information. [http://www.ncbi.nlm.nih.gov]
Gulcher JR, Jonsson P, Kong A, Kristjansson K, Frigge ML, Karason A, Einarsdottir IE, Stefansson H, Einarsdottir AS, Sigurthoardottir S, et al: Mapping of a familial essential tremor gene, FET1, to chromosome 3q13. Nat Genet. 1997, 17: 84-87.
Article
CAS
PubMed
Google Scholar
Love DR, Gardner E, Ponder BA: A polymorphic dinucleotide repeat at the D10S141 locus. Hum Mol Genet. 1993, 2: 491-
Google Scholar
Cottingham RW, Idury RM, Schaffer AA: Faster sequential genetic linkage computations. Am J Hum Genet. 1993, 53: 252-263.
PubMed
PubMed Central
Google Scholar
Kruglyak L, Daly MJ, Reeve-Daly MP, Lander ES: Parametric and nonparametric linkage analysis: a unified multipoint approach. Am J Hum Genet. 1996, 58: 1347-1363.
CAS
PubMed
PubMed Central
Google Scholar
Sobel E, Lange K: Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet. 1996, 58: 1323-1337.
CAS
PubMed
PubMed Central
Google Scholar
Risch N, Giuffra L: Model misspecification and multipoint linkage analysis. Hum Hered. 1992, 42: 77-92.
Article
CAS
PubMed
Google Scholar
Goring HH, Terwilliger JD: Linkage analysis in the presence of errors I: complex-valued recombination fractions and complex phenotypes. Am J Hum Genet. 2000, 66: 1095-1106. 10.1086/302797.
Article
CAS
PubMed
PubMed Central
Google Scholar
Goring HH, Terwilliger JD: Linkage analysis in the presence of errors II: marker-locus genotyping errors modeled with hypercomplex recombination fractions. Am J Hum Genet. 2000, 66: 1107-1118. 10.1086/302798.
Article
CAS
PubMed
PubMed Central
Google Scholar
Goring HH, Terwilliger JD: Linkage analysis in the presence of errors III: marker loci and their map as nuisance parameters. Am J Hum Genet. 2000, 66: 1298-1309. 10.1086/302846.
Article
CAS
PubMed
PubMed Central
Google Scholar
Mages HW, Rilke O, Bravo R, Senger G, Kroczek RA: NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3. Mol Endocrinol. 1994, 8: 1583-1591. 10.1210/me.8.11.1583.
CAS
PubMed
Google Scholar
Vandenbergh DJ, Persico AM, Uhl GR: A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs. Brain Res Mol Brain Res. 1992, 15: 161-166. 10.1016/0169-328X(92)90165-8.
Article
CAS
PubMed
Google Scholar
Schindelhauer D, Schuffenhauer S, Gasser T, Steinkasserer A, Meitinger T: The gene coding for glial cell line derived neurotrophic factor (GDNF) maps to chromosome 5p12-p13.1. Genomics. 1995, 28: 605-607. 10.1006/geno.1995.1202.
Article
CAS
PubMed
Google Scholar
Ishizaka Y, Itoh F, Tahira T, Ikeda I, Sugimura T, Tucker J, Fertitta A, Carrano AV, Nagao M: Human ret proto-oncogene mapped to chromosome 10q11.2. Oncogene. 1989, 4: 1519-1521.
CAS
PubMed
Google Scholar
Maisonpierre PC, Le Beau MM, Espinosa R, Ip NY, Belluscio L, de la Monte SM, Squinto S, Furth ME, Yancopoulos GD: Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations. Genomics. 1991, 10: 558-568.
Article
CAS
PubMed
Google Scholar