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Table 1 Demographic characteristics and medication use

From: Risk variants of the α-synuclein locus and REM sleep behavior disorder in Parkinson’s disease: a genetic association study

  Total (325) pRBD (141) Non-RBD (184) p value
Male:female 213:112 (65.5) 106:35 (75.2) 107:77 (58.2) < 0.01
Age, years 64.9 (9.4) 64.1 (9.4) 65.4 (9.4) 0.45
Disease duration, years 9.2 (6.9) 10.9 (7.2) 7.7 (6.4) 0.02
Levodopa yes:no 270:53 (83.6) 124:15 (87.9) 146:38 (79.3) 0.50
Agonist yes:no 213:110 (65.9) 80:59 (56.7) 133:51 (72.3) 0.03
SSRI/SNRI yes:no 52:269 (16.2) 32:106 (22.7) 20:163 (10.9) 0.02
Benzodiazepine yes:no 42:278 (15.1) 22:115 (15.6) 20:163 (10.9) 0.20
Clonazepam yes:no 19:302 (5.8) 12:126 (8.5) 7:176 (3.8) 0.50
  1. Demographic data and medication use in PD patients with and without pRBD, respectively. Numbers in parentheses refers to percentage, except for age and disease duration, where it refers to standard deviation. P values refer to binary logistic regression analyses
  2. Abbreviations: pRBD possible REM-sleep behavior disorder, SSRI selective serotonin reuptake inhibitor, SNRI serotonin and norepinephrine reuptake inhibitor