Skip to main content

Table 1 Outcome measures assessed before and after treatment with PBM

From: Improvements in clinical signs of Parkinson’s disease using photobiomodulation: a prospective proof-of-concept study

Outcome measure

test

description

Reference

Primary Outcome Measure

 Functional mobility

Timed up-and-go (TUG) test

Assessors measured the time taken for a participant to stand from a chair, walk 3 m, turn around a marker, return and sit down

[30]

Secondary Outcome Measures

 Mobility

TUG motor

As for TUG except that the participant was carrying a cup of water

[30]

TUG cognitive

As for TUG except that the participant was asked to count backwards from 40 in twos

[30]

10-m walk test (10MWT) speed

Participants walked a 10 m track. After walking 2 m, Assessors measured the time taken to walk a further 6 m

[31]

10MWT Stride length

During the 10MWT, Assessors also counted the number of strides taken to walk 6 m

[31]

 Dynamic Balance

Step test

Participants stood with feet together, 10 cm from a 10 cm high step. Assessors counted the number of times that a participant placed their foot repeatedly on the step in 15 s. Both legs were tested

[32]

 Cognition

Montreal Cognitive Assessment (MoCA)

Participant completed the MoCA test version 8.1 (www.mocatest.org), which was scored by an assessor

[33]

 Fine motor skills

Spiral test

Assessors recorded the time taken to draw between the lines of a printed Archimedean spiral. A time penalties of 3 s and 5 s were given for touching a line or crossing a line respectively. Dominant hand was tested

[34]

Nine-hole peg test (NHPT)

Assessors recorded the time taken to place 9 pegs in holes and then return the pegs to the reservoir. Both hands were tested

[35]

Micrographia

Participants were asked to write the same sentence at each assessment. The area and perimeter of each word was measured using Image J software

 

 Static Balance

Tandem stance (TS)

Assessors recorded the time that a participant could stand with one foot in front of the other (heel to toe) with eyes closed until the participant opened their eyes, a step was taken, or the participant used a hand to steady themselves. The assessment was terminated at 30 s. Both legs were tested

[36]

 

Single leg stance (SLS)

Assessors recorded the time that a participant could stand with one foot raised in the air with eyes closed until the participant opened their eyes, a step was taken, or the participant used a hand to steady themselves. The assessment was terminated at 30 s. Both legs were tested

[36]