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Table 1 Comparison of demographic and clinical characteristics between TN patients and healthy controls (HC), as well as within TN patients (responders vs. non-responders)

From: The thalamus in trigeminal neuralgia: structural and metabolic abnormalities, and influence on surgical response

 

Responders

Non-Responders

P-value

(2-tailed)

TN

HC

P-value (2-tailed)

Total #

17

6

-

23

20

-

Sex (Female/Male)

8/9

6/0

0.048*

14/9

11/9

0.70

Age (years)

58.6 \(\pm\) 9.7

47.4 \(\pm\) 10.3

0.016*

56.3 \(\pm\) 10.4

54.9 \(\pm\) 9.4

0.65

Duration of TN (years)

4.6 \(\pm\) 3.3

8.8 \(\pm\) 4.7

0.061

5.3 \(\pm\) 3.9

N/A

-

Side of pain (left/right)

6/11

2/4

 > 0.99

8/15

N/A

-

Pre-op VAS (mm)

79.9 \(\pm\) 24.1

66.8 \(\pm\) 38.7

0.50

77.6 \(\pm\) 27.3

N/A

-

NVC (yes/no)

14/3

3/3

0.27

17/6

N/A

-

NVC score (0/1/2/3)

3/3/6/5

3/0/2/1

0.64

6/3/8/6

N/A

-

Virgin (yes/no)

14/3

3/3

0.28

17/6

N/A

-

Surgery type (MVD/BC)

13/4

3/3

0.32

16/7

N/A

-

Carbamazepine/

oxcarbazepine (yes/no)

15/2

6/0

 > 0.99

21/2

N/A

-

Gabapentin/pregabalin (yes/no)

7/10

5/1

0.16

12/11

N/A

-

Other antiepileptics (yes/no)

2/15

1/5

 > 0.99

3/20

N/A

-

Antidepressant (yes/no)

2/15

1/5

 > 0.99

3/20

N/A

-

Baclofen (yes/no)

2/15

4/2

0.021*

6/17

N/A

-

Opioid (yes/no)

0/17

1/5

0.26

1/22

N/A

-

Cannabis oil (yes/no)

1/16

1/5

0.46

2/21

N/A

-

  1. Mann Whitney, and Chi-square or Fisher’s-exact tests used where appropriate. Means \(\pm\) standard deviations are presented. NVC (yes/no): neurovascular compression; NVC score (0/1/2/3)[23]: degree of neurovascular compression; Virgin (yes/no): first-time surgical treatment for TN; MVD microvascular decompression; BC balloon compression rhizotomy; other antiepileptics: lamotrigine, topiramate; antidepressant: amitriptyline, duloxetine.
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BMC Neurology

ISSN: 1471-2377

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