| |
PD-NC
|
PD-MCI
|
PDD
|
p-value
|
Post-hoc
|
|---|
|
NPI Total (frequency x severity)
|
5.4 ± 7.3
|
7.7 ± 8.7
|
9 ± 9.9
|
0.007
|
a < 0.001; b0.721
|
|
% NPI total > 1
|
60.4
|
70.2
|
72.7
|
0.126
|
a0.05; 0.518
|
|
Delirium
|
0.1 ± 0.9
|
0.2 ± 0.9
|
0 ± 0
|
0.586
|
a0.726; b0.619
|
|
% NPI > 1
|
2.3
|
4.3
|
0
|
0.432
|
a0.246; b0.441
|
|
Hallucinations
|
0.1 ± 0.7
|
0.3 ± 1.5
|
0.3 ± 0.8
|
0.162
|
a0.150; b0.951
|
|
% NPI > 1
|
3.3
|
7.1
|
9.5
|
0.138
|
a0.088; b0.496
|
|
Agitation
|
0.4 ± 1.2
|
0.5 ± 1.3
|
0.9 ± 1.7
|
0.183
|
a0.585; b0.525
|
|
% NPI > 1
|
9.1
|
13.5
|
19
|
0.198
|
a0.141; b0.362
|
|
Depression/dysphoria
|
1.3 ± 2.1
|
2 ± 2.9
|
2.2 ± 3.4
|
0.020
|
a0.034; b0.258
|
|
% NPI > 1
|
21.8
|
41.8
|
33.8
|
0.055
|
a < 0.05; b0.320
|
|
Anxiety
|
1.4 ± 2.3
|
1.6 ± 2.3
|
1.5 ± 2.1
|
0.708
|
a0.684; b0.988
|
|
% NPI > 1
|
33
|
39.2
|
34.8
|
0.537
|
a0.160; b0.445
|
|
Euphoria
|
0.2 ± 0.9
|
0.2 ± 0.8
|
0 ± 0
|
0.666
|
a0.934; b0.548
|
|
% NPI > 1
|
4.7
|
6.3
|
0
|
0.460
|
a0.340; b0.293
|
|
Apathy
|
0.9 ± 2
|
1.9 ± 3
|
2.3 ± 2.7
|
< 0.001
|
a < 0.001; b0.839
|
|
% NPI > 1
|
21.4
|
35.4
|
42.9
|
< 0.005
|
a < 0.005; b0.341
|
|
Disinhibition
|
0.06 ± 0.4
|
0.1 ± 0.6
|
0 ± 0
|
0.183
|
a0.230; b0.341
|
|
% NPI > 1
|
1.7
|
3.2
|
0
|
0.520
|
a0.294; b0.543
|
|
Irritability
|
0.8 ± 1.6
|
1.1 ± 2
|
1.3 ± 2.3
|
0.132
|
a0.207; b0.930
|
|
% NPI > 1
|
20
|
27.4
|
27.3
|
0.265
|
a0.086; b0.610
|
|
Aberrant motor behaviour
|
0.2 ± 1
|
0.2 ± 0.7
|
0.7 ± 2.1
|
0.102
|
a0.985; b0.134
|
|
% NPI > 1
|
4
|
6.4
|
9.5
|
0.373
|
a0.238; b0.448
|
- a p ≤ 0.05 significance based on paired t-test. (PD-NC vs PD-MCI)
- b p ≤ 0.05 significance based on paired t-test. (PD-MCI vs PDD)
