Table 1 Demographic and clinical characteristics of neonates diagnosed with HIE and underwent cooling

Gestation (weeks)

39.16 ± 1.60

39.60 ± 1.48

39.05 ± 1.62

0.120

Preterm < 37 weeks gestation^a

15 (12.3%)

3 (11.5%)

12 (12.5%)

0.895

Birth weight (grams)

3199.07 ± 699.65

3224.04 ± 899.76

3192.37 ± 641.13

0.839

Female sex

57 (46.3%)

12 (46.2%)

45 (46.4%)

0.983

C-section

81 (65.9%)

18 (69.2%)

63 (64.9%)

0.683

Non-reassuring fetal heart tone^a

85 (69.7%)

19 (73.1%)

66 (68.8%)

0.670

Pre-eclampsia^a

6 (4.9%)

0 (0.0%)

6 (6.3%)

0.191

Placental abruption, uterine rupture or cord prolapse^a

20 (16.4%)

4 (15.4%)

16 (16.7%)

0.876

Meconium stain^a

53 (43.4%)

14 (53.8%)

39 (40.6%)

0.228

Nuchal cord^a

24 (19.7%)

5 (19.2%)

19 (19.8%)

0.949

Maternal chorioamnionitis^a

12 (9.8%)

4 (15.4%)

8 (8.3%)

0.284

Intubation

84 (68.3%)

22 (84.6%)

62 (63.9%)

< 0.05

Chest compressions

37 (30.1%)

10 (38.5%)

27 (27.8%)

0.294

Day of life MRI completed

5.99 ± 1.13

6.38 ± 1.63

5.89 ± 0.93

< 0.05

Mortality during hospitalization

7 (5.7%)

6 (23.1%)

1 (1.0%)

< 0.001

Lowest blood pH < 7.1

100 (81.3%)

22 (84.6%)

78 (80.4%)

0.625

Apgar 1 min ≤ 5^a

118 (96.7%)

24 (92.3%)

94 (97.9%)

0.154

Apgar 5 min ≤ 5^a

86 (70.5%)

21 (80.08%)

65 (67.7%)

0.195

Apgar 10 min ≤ 5^b

42 (37.8%)

14 (60.9%)

28 (31.8%)

< 0.05

 Mild

10 (8.1%)

2 (7.7%)

8 (8.2%)

0.135

 Moderate

95 (77.2%)

17 (65.4%)

78 (80.4%)

 Severe

18 (14.6%)

7 (26.9%)

11 (11.3%)