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  1. Parkinson’s disease (PD) complexity poses challenges for individuals with Parkinson’s, providers, and researchers. A recent multisite randomized trial of a proactive, telephone-based, nurse-led care management...

    Authors: Karen I. Connor, Hilary C. Siebens, Brian S. Mittman, David A. Ganz, Frances Barry, Donna K. McNeese-Smith, Eric M. Cheng and Barbara G. Vickrey
    Citation: BMC Neurology 2022 22:36
    Content type: Research Published on:

  2. The burden of Parkinson’s disease (PD) worsens with disease progression. However, the lack of objective and uniform disease classification challenges our understanding of the incremental burden in patients wit...

    Authors: Irene A. Malaty, Pablo Martinez-Martin, K. Ray Chaudhuri, Per Odin, Matej Skorvanek, Joohi Jimenez-Shahed, Michael J. Soileau, Susanna Lindvall, Josefa Domingos, Sarah Jones, Ali Alobaidi, Yash J. Jalundhwala, Prasanna L. Kandukuri, Koray Onuk, Lars Bergmann, Samira Femia…
    Citation: BMC Neurology 2022 22:35
    Content type: Research Published on:

  4. The results of various studies that have so far evaluated the influence of meteorological conditions on seizures are often divergent. No studies have been performed so far that evaluate the possible correlatio...

    Authors: Sanja Tomasović, Josip Sremec, Jelena Košćak Lukač, Gordana Sičaja, Koraljka Bačić Baronica, Vedran Ostojić, Zurap Raifi, Nada Tomić Sremec, Dunja Plačko-Vršnak, Lidija Srnec and Krunoslav Mikec
    Citation: BMC Neurology 2022 22:33
    Content type: Research article Published on:

  5. For recurrent glioblastoma (GB) patients, several therapy options have been established over the last years such as more aggressive surgery, re-irradiation or chemotherapy. Age and the Karnofsky Performance St...

    Authors: Melanie Barz, Stefanie Bette, Insa Janssen, A. Kaywan Aftahy, Thomas Huber, Friederike Liesche-Starnecker, Yu-Mi Ryang, Benedikt Wiestler, Stephanie E. Combs, Bernhard Meyer and Jens Gempt
    Citation: BMC Neurology 2022 22:32
    Content type: Research article Published on:

  6. To determine the prevalence and to characterize the different types of strokes in children with cancer at the Children’s Cancer Center of Lebanon (CCCL), in addition to assess the factors and clinical findings...

    Authors: Catherina Zadeh, Natally AlArab, Samar Muwakkit, Lamya A. Atweh, Hani Tamim, Maha Makki, Hamza A. Salhab and Roula Hourani
    Citation: BMC Neurology 2022 22:31
    Content type: Research Published on:

  7. The present study intended to analyze the outcome of patients with severe brain injury one-year after discharge from early rehabilitation.

    Authors: Melanie Boltzmann, Simone B. Schmidt, Christoph Gutenbrunner, Joachim K. Krauss, Günter U. Höglinger and Jens D. Rollnik
    Citation: BMC Neurology 2022 22:30
    Content type: Research Published on:

  8. Recovery of walking ability is an important goal for patients poststroke, and a basic level of mobility is critical for an early discharge home. Caregiver-mediated exercises could be a resource-efficient strat...

    Authors: Marijn Mulder, Corien Nikamp, Rinske Nijland, Erwin van Wegen, Erik Prinsen, Judith Vloothuis, Jaap Buurke and Gert Kwakkel
    Citation: BMC Neurology 2022 22:29
    Content type: Study protocol Published on:

  10. Patients with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis who also present with status epilepticus (SE) often have a poor prognosis. The aim of this study is to explore simple and effective predict...

    Authors: Yingying Liu, Lili Ma, Xiaomeng Ma, Xueying Ma, Jing Li, Donghong Li, Xiuli Lin, Zhumin Su and Xiaohong Chen
    Citation: BMC Neurology 2022 22:27
    Content type: Research Published on:

  12. Reducing percutaneous endoscopic gastrostomies with jejunal extension tubes (PEG-J) related complications is vital to the long-term preservation of duodenal levodopa infusion (DLI) in advanced Parkinson’s dise...

    Authors: Simone Simoni, Pasquale Nigro, Marta Filidei, Giulia Cappelletti, Federico Paolini Paoletti, Danilo Castellani, Mirko Gaggiotti, Lucilla Parnetti and Nicola Tambasco
    Citation: BMC Neurology 2022 22:25
    Content type: Research article Published on:

  13. The impact of near-total resection of IDH-mutated anaplastic glioma (IDHmutAG) is well-established but there remains uncertainty of benefit in tumours of the insular cortex where the extent of safe resection m...

    Authors: Gabrielle Metz, Dasantha Jayamanne, Helen Wheeler, Matthew Wong, Raymond Cook, Nicholas Little, Jonathon Parkinson, Marina Kastelan, Chris Brown and Michael Back
    Citation: BMC Neurology 2022 22:24
    Content type: Research Published on:

  14. Perinatal stroke (PS) is the leading cause of hemiparetic cerebral palsy (CP). Involvement of the corticospinal tract on neonatal magnetic resonance imaging (MRI) is predictive of motor outcome in patients wit...

    Authors: Nigul Ilves, Silva Lõo, Norman Ilves, Rael Laugesaar, Dagmar Loorits, Pille Kool, Tiina Talvik and Pilvi Ilves
    Citation: BMC Neurology 2022 22:23
    Content type: Research Published on:

  15. We investigated the impact of the Corona Virus Disease 2019 (COVID-19) pandemic and the resulting lockdown on reperfusion treatments and door-to-treatment times during the first surge in Dutch comprehensive st...

    Authors: Faysal Benali, Lotte J. Stolze, Anouk D. Rozeman, Wouter Dinkelaar, Jonathan M. Coutinho, Bart J. Emmer, Rob A. R. Gons, Lonneke F. S. Yo, Julia H. van Tuijl, Issam Boukrab, Dianne H. K. van Dam-Nolen, Ido R. van den Wijngaard, Geert J. Lycklama à Nijeholt, Karlijn F. de Laat, Lukas C. van Dijk, Heleen M. den Hertog…
    Citation: BMC Neurology 2022 22:22
    Content type: Research Published on:

  16. Immersive virtual reality (VR)-based motor control training (VRT) is an innovative approach to improve motor function in patients with stroke. Currently, outcome measures for immersive VRT mainly focus on moto...

    Authors: Chien-Yu Huang, Wei-Chi Chiang, Ya-Chin Yeh, Shih-Chen Fan, Wan-Hsien Yang, Ho-Chang Kuo and Ping-Chia Li
    Citation: BMC Neurology 2022 22:21
    Content type: Research Published on:

  17. Pontocerebellar hypoplasia (PCH) is increasingly known as a degenerative disease rather than simple “hypoplasia”. At least 21 disease-causing genes have been identified for PCH so far. Because PCH is very hete...

    Authors: Mamiko Yamada, Hisato Suzuki, Hiroyuki Adachi, Atsuko Noguchi, Fuyuki Miya, Tsutomu Takahashi and Kenjiro Kosaki
    Citation: BMC Neurology 2022 22:20
    Content type: Case report Published on:

  18. The influence of chronic kidney disease (CKD) on the severity and prognosis of spontaneous intracerebral hemorrhage (ICH) has been scarcely investigated. We aimed to explore the association of admission estima...

    Authors: Zhaoxia Li, Zixiao Li, Qi Zhou, Hongqiu Gu, Yongjun Wang and Xingquan Zhao
    Citation: BMC Neurology 2022 22:19
    Content type: Research Published on:

  19. We report the case of a patient with recurrent episodes of disturbed memory suggestive of transient epileptic amnesia, and a focal hippocampal lesion typically associated with transient global amnesia. We argu...

    Authors: Eckhard Schlemm, Tim Magnus, Leander D. Rimmele, Justine Münsterberg, Maxim Bester, Simon S. Kessner, Mathias Gelderblom and Christian Gerloff
    Citation: BMC Neurology 2022 22:18
    Content type: Case report Published on:

  20. Charcot-Marie-Tooth disease (CMT) is a genetically heterogeneous hereditary neuropathy, and CMT1A is the most common form; it is caused by a duplication of the peripheral myelin protein 22 (PMP22) gene. Mutations...

    Authors: Haitian Nan, Yunqing Wu, Shilei Cui, Houliang Sun, Jiawei Wang, Ying Li, Lingchao Meng, Takamura Nagasaka and Liyong Wu
    Citation: BMC Neurology 2022 22:17
    Content type: Case report Published on:

  21. Progressive haemorrhagic injury after surgery in patients with traumatic brain injury often results in poor patient outcomes. This study aimed to develop and validate a practical predictive tool that can relia...

    Authors: Tiange Chen, Siming Chen, Yun Wu, Yilei Chen, Lei Wang and Jinfang Liu
    Citation: BMC Neurology 2022 22:16
    Content type: Research Published on:

  22. An increased susceptibility to COVID-19 has been suggested for individuals with neurodegenerative diseases, but data are scarce from longitudinal studies.

    Authors: Yihan Hu, Huazhen Yang, Can Hou, Wenwen Chen, Hanyue Zhang, Zhiye Ying, Yao Hu, Yajing Sun, Yuanyuan Qu, Maria Feychting, Unnur Valdimarsdottir, Huan Song and Fang Fang
    Citation: BMC Neurology 2022 22:15
    Content type: Research article Published on:

  23. Temporal lobe epilepsy (TLE) is commonly refractory. Epilepsy surgery is an effective treatment strategy for refractory epilepsy, but patients with a history of focal to bilateral tonic-clonic seizures (FBTCS)...

    Authors: Liluo Nie, Yanchun Jiang, Zongxia Lv, Xiaomin Pang, Xiulin Liang, Weiwei Chang and Jinou Zheng
    Citation: BMC Neurology 2022 22:14
    Content type: Research Published on:

  24. Parkinson’s disease (PD) is associated with enteric nervous system dysfunction and gut microbiota dysbiosis. Short-chain fatty acids (SCFAs), derived from gut microbiota, are supposed to anticipate PD pathogen...

    Authors: Gang Wu, Zhengli Jiang, Yaling Pu, Shiyong Chen, Tingling Wang, Yajing Wang, Xiaoping Xu, Shanshan Wang, Minya Jin, Yangyang Yao, Yang Liu, Shaofa Ke and Suzhi Liu
    Citation: BMC Neurology 2022 22:13
    Content type: Research Published on:

  26. Myoclonus-dystonia is a rare movement disorder with an autosomal dominant inheritance pattern characterized by a combination of myoclonic jerks and dystonia that may have psychiatric manifestations. Our aim is...

    Authors: Meliza Angelica J. de Leon, Raymond L. Rosales, Christine Klein and Ana Westenberger
    Citation: BMC Neurology 2022 22:11
    Content type: Case report Published on:

  27. Leukoencephalopathy with brain calcifications and cysts (LCC; also known as Labrune syndrome) is a rare genetic microangiopathy caused by biallelic mutations in SNORD118. The mechanisms by which loss-of-function ...

    Authors: Michelle Paff, Nardin Samuel, Noor Alsafwani, Darcia Paul, Phedias Diamandis, Seth A. Climans, Walter Kucharczyk, Mandy Yi Rong Ding, Andrew F. Gao and Andres M. Lozano
    Citation: BMC Neurology 2022 22:10
    Content type: Case report Published on:

  28. Guillain–Barré syndrome (GBS) and spinal epidural abscess (SEA) are known as mimics of each other because they present with flaccid paralysis following an infection; however, they differ in the main causative ...

    Authors: Masako Fujita, Tatsuya Ueno, Michiru Horiuchi, Tatsuro Mitsuhashi, Shouji Yamamoto, Akira Arai and Masahiko Tomiyama
    Citation: BMC Neurology 2022 22:9
    Content type: Case report Published on:

  29. Growing evidence suggests a mutual interaction between gut microbiome alterations and ALS pathogenesis. However, previous studies were susceptible to potential confounding factors and reverse causation bias, l...

    Authors: Linjing Zhang, Zhenhuang Zhuang, Gan Zhang, Tao Huang and Dongsheng Fan
    Citation: BMC Neurology 2022 22:8
    Content type: Research Published on:

  30. Transient ischemic attack (TIA) is an important predictor for a pending stroke. Guidelines recommend a workup for TIA-patients similar to that of stroke patients, including an assessment of the extra- and intr...

    Authors: Ilko L. Maier, Gerrit U. Herpertz, Mathias Bähr, Marios-Nikos Psychogios and Jan Liman
    Citation: BMC Neurology 2022 22:7
    Content type: Research article Published on:

  31. This study assessed the predictive factors for symptomatic intracranial hemorrhage (sICH) in patients with acute ischemic stroke (AIS) after receiving intravenous thrombolysis (IVT) within 6 h in northern China.

    Authors: Yuan Xue, Shan Li, Yuanyuan Xiang, Ziran Wang, Fengyun Wang, Yuanying Yu, Peng Yan, Xiaohui Liu, Qinjian Sun, Yifeng Du and Jifeng Li
    Citation: BMC Neurology 2022 22:6
    Content type: Research Published on:

  32. Sleep characteristics associated with dementia are poorly defined and whether their associations vary by demographics and APOE genotype among older adults are unclear.

    Authors: Rui Liu, Shi Tang, Yongxiang Wang, Yi Dong, Tingting Hou, Yifei Ren, Lin Cong, Keke Liu, Yu Qin, Shireen Sindi, Yifeng Du and Chengxuan Qiu
    Citation: BMC Neurology 2022 22:5
    Content type: Research Published on:

  33. Headache is one of the most disturbing complaints worldwide, negatively impacting social and regular life activities. In the background of stressful life in medical schools, adding to the stressful situation i...

    Authors: Firas Anaya, Wala’a Abu Alia, Feda’a Hamoudeh, Zaher Nazzal and Beesan Maraqa
    Citation: BMC Neurology 2022 22:4
    Content type: Research Published on:

  34. A decrease in hippocampal neurogenesis is considered an important cause of cognitive impairment, while changes in mossy fiber sprouting are closely related to development of spontaneous recurrent seizures in c...

    Authors: Shanshan Zhao, Fangxi Liu, Wei Shi, Jialu Wang, Zhike Zhou and Xiaoqian Zhang
    Citation: BMC Neurology 2022 22:3
    Content type: Research Published on:

  35. The detailed neuropathological features of patients with autosomal recessive hereditary spastic paraplegia with a thin corpus callosum (TCC) and SPG11 mutations are poorly understood, as only a few autopsies have...

    Authors: Mika Hayakawa, Tomoyasu Matsubara, Yoko Mochizuki, Chisen Takeuchi, Motoyuki Minamitani, Masayuki Imai, Kenjiro Kosaki, Tomio Arai and Shigeo Murayama
    Citation: BMC Neurology 2022 22:2
    Content type: Case report Published on:

  36. This study was performed to identify the association between the total magnetic resonance imaging burden of small vessel disease and the occurrence of post-stroke dysphagia in patients with a single recent sma...

    Authors: Lulu Zhang, Xiang Tang, Yidan Li, Juehua Zhu, Dongxue Ding, Yun Zhou, Shanshan Diao, Yan Kong, Xiuying Cai, Ye Yao and Qi Fang
    Citation: BMC Neurology 2022 22:1
    Content type: Research Published on:

  37. The purpose of this study was to examine the associations between combined and individual cerebral small vessel disease (cSVD) markers on future walking speed over 9 years; and to explore whether these associa...

    Authors: Emerald G. Heiland, Anna-Karin Welmer, Grégoria Kalpouzos, Anna Laveskog, Rui Wang and Chengxuan Qiu
    Citation: BMC Neurology 2021 21:496
    Content type: Research Published on:

  38. Toscana virus (TOSV) is an arthropod-borne virus transmitted by phlebotomine sandflies (Phlebotomus sp.) widespread throughout the Mediterranean having the potential to cause meningoencephalitis in humans. In Ger...

    Authors: R. Dersch, A. Sophocleous, D. Cadar, P. Emmerich, J. Schmidt-Chanasit and S. Rauer
    Citation: BMC Neurology 2021 21:495
    Content type: Research Published on:

  39. Blood-brain barrier (BBB) injury is prevalent in patients with HIV-associated dementia (HAD) and is a frequent feature of HIV encephalitis. Signs of BBB damage are also sometimes found in neuroasymptomatic HIV...

    Authors: Birgitta Anesten, Henrik Zetterberg, Staffan Nilsson, Bruce J. Brew, Dietmar Fuchs, Richard W. Price, Magnus Gisslén and Aylin Yilmaz
    Citation: BMC Neurology 2021 21:494
    Content type: Research Published on:

    The Correction to this article has been published in BMC Neurology 2022 22:197

  40. Cranial autonomic symptoms are common in migraine, with eye redness and tearing being the most common ones. Their identification can help to avoid misdiagnosis, predict the disease course, and select the appro...

    Authors: Mansoureh Togha, Elham Jafari, Atieh Moosavian, Abolfazl Farbod, Shadi Ariyanfar and Fatemeh Farham
    Citation: BMC Neurology 2021 21:493
    Content type: Research article Published on:

  42. Impaired motor function is one of the early symptoms shown in patients with Parkinson Disease (PD). For this reason, rehabilitative interventions have been used for many years to improve motor and non-motor sy...

    Authors: Patricia Abril-Jiménez, Beatriz Merino-Barbancho, Cecilia Vera-Muñoz and María Teresa Arredondo Waldmeyer
    Citation: BMC Neurology 2021 21:491
    Content type: Research Published on:

  43. Encephalitis associated with antibodies against alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) is an extremely rare type of antibody-mediated encephalitis. This research aims to inve...

    Authors: Zhe Zhang, Siyuan Fan, Haitao Ren, Lixin Zhou and Hongzhi Guan
    Citation: BMC Neurology 2021 21:490
    Content type: Research Published on:

  44. Dural chondrosarcoma is a very rare intracranial tumor, given that meninges do not normally contain cartilaginous tissue from which it can originate. We present a case of primary extraosseous dural chondrosarc...

    Authors: Francis Garay Buitron, Albert Pons-Escoda, Noemí Vidal, Alberto Torres and Angels Camins
    Citation: BMC Neurology 2021 21:489
    Content type: Case report Published on:

  45. A previously shown ‘mismatch’ group of patients with good observed upper limb (UL) motor function but low perceived UL activity at six months post stroke tends to use the affected UL less in daily life than wo...

    Authors: Bea Essers, Annick Van Gils, Christophe Lafosse, Marc Michielsen, Hilde Beyens, Fabienne Schillebeeckx, Janne M. Veerbeek, Andreas R. Luft, Daphne Kos and Geert Verheyden
    Citation: BMC Neurology 2021 21:488
    Content type: Research Published on:

  46. Glycemic patterns have been reported to be prognostic factors for stroke; however, this remains to be further evaluated. This meta-analysis aimed to evaluate the usefulness of glycemic patterns such as persist...

    Authors: Duanlu Hou, Ping Zhong, Xiaofei Ye and Danhong Wu
    Citation: BMC Neurology 2021 21:487
    Content type: Research article Published on:

  47. Erenumab is a calcitonin gene-related peptide (CGRP)-receptor antibody inhibiting CGRP function. CGRP is prominently involved in the pathophysiology of migraine through nociceptive modulation in the trigeminov...

    Authors: Bui Bao Khanh Dinh, Waseem Hamed Aziz, Alessandro Terruzzi and Derk Wolfgang Krieger
    Citation: BMC Neurology 2021 21:486
    Content type: Research Published on:

  48. Vaccination against COVID-19 continues apace, but side-effects, both common and severe, continue to be reported. We report here the first published case of COVID-19 vaccine-related encephalitis.

    Authors: Junko Takata, Simon M. Durkin, Solomon Wong, Michael S. Zandi, Josephine K. Swanton and Tumena W. Corrah
    Citation: BMC Neurology 2021 21:485
    Content type: Case report Published on:

  49. Central sensitization is an amplification of neuronal signaling within the central nervous system. The Central Sensitization Inventory was introduced in 2012. A Polish version of the CSI (CSI-Pol) was develope...

    Authors: Barbara Kosińska, Beata Tarnacka, Paweł Turczyn, Grażyna Gromadzka, Małgorzata Malec-Milewska, Dorota Janikowska-Hołowenko and Randy Neblett
    Citation: BMC Neurology 2021 21:483
    Content type: Research Published on:

  50. The development of intraventricular hemorrhage (IVH) in aneurysmal subarachnoid hemorrhage (aSAH) is linked with higher mortality and poor neurological recovery. Previous studies have investigated the effect o...

    Authors: Hae Gi Park, Sunghan Kim, Joonho Chung, Chang Ki Jang, Keun Young Park and Jae Whan Lee
    Citation: BMC Neurology 2021 21:482
    Content type: Research Published on:
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BMC Neurology

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