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  1. Patients who develop hospital-onset unresponsiveness should be promptly managed in order to avoid clinical deterioration. Pupillary examination through pupillary light reflex is the gold standard method in the...

    Authors: Hyunjo Lee, Soh Hyun Choi, Bobin Park, Yoon-Hee Hong, Han-Bin Lee and Sang-Beom Jeon
    Citation: BMC Neurology 2021 21:234
  2. Gliosarcoma (GS) refers to the presence of mesenchymal differentiation (as seen using light microscopy) in the setting of glioblastoma (GB, an astrocytoma, WHO Grade 4). Although the same approach to treatment...

    Authors: Christopher Dardis, David Donner, Nader Sanai, Joanne Xiu, Sandeep Mittal, Sharon K. Michelhaugh, Manjari Pandey, Santosh Kesari, Amy B. Heimberger, Zoran Gatalica, Michael W. Korn, Ashley L. Sumrall and Surasak Phuphanich
    Citation: BMC Neurology 2021 21:231

    The Publisher Correction to this article has been published in BMC Neurology 2021 21:316

  3. Dynamic axial computed tomographic angiography (dynax–CTA), covering a thin width, with a focus on the bilateral middle cerebral artery (MCA), can quickly visualize the internal carotid artery (ICA) or MCA occ...

    Authors: Takahisa Mori, Kazuhiro Yoshioka, Wataru Mori and Yuhei Tanno
    Citation: BMC Neurology 2021 21:230
  4. Ischemic events are the most common postoperative complication in bypass surgery for moyamoya disease (MMD), but the risk factors for pediatric MMD remain unclear. The goal of the study was to investigate the ...

    Authors: Xiaofeng Deng, Peicong Ge, Rong Wang, Dong Zhang, Jizong Zhao and Yan Zhang
    Citation: BMC Neurology 2021 21:229
  5. This retrospective study evaluates patient-reported outcomes in patients with multiple sclerosis (MS) spasticity who were treated with a cannabinoid oromucosal spray (Sativex®, USAN name: nabiximols) after not...

    Authors: Marie D’hooghe, Barbara Willekens, Valerie Delvaux, Miguel D’haeseleer, Daniel Guillaume, Guy Laureys, Guy Nagels, Patrick Vanderdonckt, Vincent Van Pesch and Veronica Popescu
    Citation: BMC Neurology 2021 21:227
  6. We aim to compare the effect of long-term anti-seizure medication (ASM) monotherapy on the risk of death and new ischemic stroke in patients with post-stroke epilepsy (PSE).

    Authors: Chia-Yu Hsu, Chun-Yu Cheng, Jiann-Der Lee, Meng Lee and Bruce Ovbiagele
    Citation: BMC Neurology 2021 21:226
  7. The global status of the COVID-19 pandemic is not optimistic. This is a particularly vulnerable time for patients with pre-existing headache disorders. The present study aimed to investigate the impact of the ...

    Authors: Qiaoyu Gong, Shuping Liu, Ruiting Li, Lihua Yao and Zheman Xiao
    Citation: BMC Neurology 2021 21:224
  8. Since subjects with Rett syndrome (RTT) focus their attention mainly on the faces of people with whom they interact, in this study the role of a human-like smart interactive agent (an avatar) in enhancing cogn...

    Authors: Rosa Angela Fabio, Giorgia Pergolizzi, Andrea Nucita, Giancarlo Iannizzotto and Tindara Caprì
    Citation: BMC Neurology 2021 21:223
  9. Presentation with massive systemic embolization as the initial manifestation of occult malignancy is infrequent. The standard management of cancer-related arterial thromboembolism has not yet been established.

    Authors: Zheng Wang, Jiangyong Miao, Lina Wang, Ying Liu, Hui Ji, Xiangjian Zhang and Lili Cui
    Citation: BMC Neurology 2021 21:221
  10. Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) is an adult-onset rare monogenic microvasculopathy. Its typical neuroimaging features are punctate white matter lesio...

    Authors: Yuying Yan, Shuai Jiang, Ruilin Wang, Xiang Wang, Peng Li and Bo Wu
    Citation: BMC Neurology 2021 21:219
  11. Cognitive impairment is one of the common features of multiple sclerosis (MS). Despite high prevalence, cognitive decline is often overlooked by neurologists. The Brief International Cognitive Assessment for M...

    Authors: Nazibrola Botchorishvili, Nino Shiukashvili, Nina Mikeladze, Ann Dzagnidze, Nino Mikava, Maia Tighashvili and Marina Janelidze
    Citation: BMC Neurology 2021 21:218
  12. Lacosamide (LCM) is the antiepileptic drug approved by the U.S. Food and Drug Administration in 2008 that facilitates slow activation of the voltage-gated sodium channels. Neutropenia and cardiac events includ...

    Authors: Makoto Shibata, Reona Hoshino, Chisato Shimizu, Masayuki Sato, Natsumi Furuta and Yoshio Ikeda
    Citation: BMC Neurology 2021 21:217
  13. The concept of clinical ethics consultation (CECs) was implemented to provide support in ethical controversies in clinical settings and are offered in at least every second hospital in Germany. Neurological di...

    Authors: Benjamin Ilse, Bernd Alt-Epping, Albrecht Günther, Jan Liman and Alfred Simon
    Citation: BMC Neurology 2021 21:216
  14. Chronic inflamed tissue in nasal cavity is a rare complication of transsphenoidal approach (TSA). Inflamed tissue is rich in blood vessels, which can lead to frequent nosebleeds. In addition, chronic inflammat...

    Authors: Ja Yoon Kim, Yong Bae Kim and Joonho Chung
    Citation: BMC Neurology 2021 21:215
  15. DDMS is a rare disease diagnosed by clinical and radiological characteristics. But the complexity of radiological and clinical manifestations of DDMS has become a challenge diagnostically. To date, the reporte...

    Authors: Bing Wang, Wentao Jiang, Weiqiang Yan, Jianhong Tian, Jianxing Xu, Yulin Li, Yanzhen Zhao, Yi Dai, Guanxun Cheng and Gangqiang Hou
    Citation: BMC Neurology 2021 21:213
  16. Primary right brachium pontis germinoma with hypertrophic olivary degeneration (HOD) is extremely rare. A preoperative diagnosis is challenging due to the absence of characterized clinical and neuroimaging fea...

    Authors: Yanong Li, Peng Wang, Jin Feng, Jiayi Wang, Jing Zhang and Xiaoguang Qiu
    Citation: BMC Neurology 2021 21:210
  17. Atrial Fibrillation (AF) is a common cardiac arrhythmia and has been identified as a major risk factor for acute ischemic stroke (AIS). Gender differences in the disease process, causative mechanisms and outco...

    Authors: Chase Rathfoot, Camron Edrissi, Carolyn Breauna Sanders, Krista Knisely, Nicolas Poupore and Thomas Nathaniel
    Citation: BMC Neurology 2021 21:209
  18. Cerebrovascular disorders have occurred more frequently in some Central Nervous System (CNS) disorders, such as epilepsy. Some CNS drugs have been associated with increased stroke risk. Our aim was to estimate...

    Authors: Maria Giner-Soriano, Josep Ramon Marsal, Ainhoa Gomez-Lumbreras and Rosa Morros
    Citation: BMC Neurology 2021 21:208
  19. Treating chordoma through surgery alone is often ineffective. Thus, surgery often performed with irradiation, with a reported 5-year survival rate of 60–75%. The clinical course varies, and disease rarity prev...

    Authors: Yoshikazu Ogawa, Hidefumi Jokura and Teiji Tominaga
    Citation: BMC Neurology 2021 21:207
  20. Ala97Ser transthyretin amyloidosis-associated polyneuropathy (ATTRA97S-PN) is a rare form of inherited polyneuropathy, usually manifesting with late-onset (> 50) progressive polyneuropathy. This mutation is mo...

    Authors: Nath Pasutharnchat, Chamaiporn Taychargumpoo, Yongkasem Vorasettakarnkij and Jakkrit Amornvit
    Citation: BMC Neurology 2021 21:206
  21. Heterogenous central nervous system (CNS) neurologic manifestations of polyarteritis nodosa (PAN) are underrecognized. We review three cases of patients with PAN that illustrate a range of nervous system patho...

    Authors: Cathra Halabi, Erika K. Williams, Ramin A. Morshed, Mauro Caffarelli, Christine Anastasiou, Tarik Tihan, Daniel Cooke, Adib A. Abla, Christopher F. Dowd, Vinil Shah, Sharon Chung and Megan B. Richie
    Citation: BMC Neurology 2021 21:205
  22. Since the nineteenth century, a great variety of crossed brainstem syndromes (CBS) have been described in the medical literature. A CBS typically combines ipsilateral cranial nerves deficits to contralateral l...

    Authors: Nathan Beucler, Sébastien Boissonneau, Aurélia Ruf, Stéphane Fuentes, Romain Carron and Henry Dufour
    Citation: BMC Neurology 2021 21:204
  23. Autoimmune encephalitis (AE) is now considered a main, potentially curable cause of encephalitis, but remains conspicuously underreported from South Asia. We studied the clinical characteristics in relation to...

    Authors: Nilanka Wickramasinghe, Dhanushka Dasanayake, Neelika Malavige, Rajiva de Silva and Thashi Chang
    Citation: BMC Neurology 2021 21:203
  24. Spinal neuroarthropathy (SNA), also known as Charcot spine, is an uncommon aggressive arthropathy, secondary to loss of proprioceptive and nociceptive feedback from the spine. A diagnosis of SNA is frequently ...

    Authors: Barbara Limberger Nedel, Juliana Avila Duarte and Fernando Gerchman
    Citation: BMC Neurology 2021 21:202
  25. Characterization of prediagnostic Parkinson’s Disease (PD) and early prediction of subsequent development are critical for preventive interventions, risk stratification and understanding of disease pathology. ...

    Authors: William Yuan, Brett Beaulieu-Jones, Richard Krolewski, Nathan Palmer, Christine Veyrat-Follet, Francesca Frau, Caroline Cohen, Sylvie Bozzi, Meaghan Cogswell, Dinesh Kumar, Catherine Coulouvrat, Bruno Leroy, Tanya Z. Fischer, S. Pablo Sardi, Karen J. Chandross, Lee L. Rubin…
    Citation: BMC Neurology 2021 21:201
  26. Subjective Memory Complaints (SMC) in elderly people due to preclinical Alzheimer’s Disease may be associated with dysregulation of the Kynurenine Pathway (KP), with an increase in neurotoxic metabolites that ...

    Authors: Julia K. Stroehlein, Solveig Vieluf, Philipp Zimmer, Alexander Schenk, Max Oberste, Christian Goelz, Franziska van den Bongard and Claus Reinsberger
    Citation: BMC Neurology 2021 21:200
  27. The Low-profile Visualized Intraluminal Support (LVIS) device is a self-expanding, nitinol, single-braid, closed-cell device that was recently developed for endovascular embolization of intracranial aneurysms....

    Authors: Quanlong Hong, Wenqiang Li, Jing Ma, Peng Jiang and Yisen Zhang
    Citation: BMC Neurology 2021 21:198
  28. Neurological outcome and mortality of patients suffering from poor grade subarachnoid hemorrhage (SAH) may have changed over time. Several factors, including patients’ characteristics, the presence of hydrocep...

    Authors: Elisa Gouvêa Bogossian, Daniela Diaferia, Andrea Minini, Narcisse Ndieugnou Djangang, Marco Menozzi, Lorenzo Peluso, Filippo Annoni, Jacques Creteur, Sophie Schuind, Olivier Dewitte and Fabio Silvio Taccone
    Citation: BMC Neurology 2021 21:196
  29. The effects of BRAFnon-V600E and BRAFV600E on the outcomes and the molecular characteristics of adult glioma patients are unknown and need to be explored, although BRAFV600E has been extensively studied in pediat...

    Authors: Wei Wang, Maode Wang, Haitao Jiang, Tuo Wang and Rong Da
    Citation: BMC Neurology 2021 21:195
  30. The impact of nocturnal disturbance (ND) in Parkinson’s disease on quality of life of patients in Western Countries is increasingly understood. Our study aimed to investigate ND prevalence and its quality of l...

    Authors: Guiying He, Chun-Feng Liu, Qinyong Ye, Zhenguo Liu, Miao Jin, Huifang Shang, Ling Chen, Houzhen Tuo, Hong Jiang, Jifu Cai, Kalpesh Joshi, James Cooper, Lu Zi and Shengdi Chen
    Citation: BMC Neurology 2021 21:194
  31. In patients with multiple sclerosis (MS), the disease’s complications and manifestations affect a person’s ability to function normally and leads to further disruptions in their education, family life, job opp...

    Authors: Atefeh Homayuni, Sedigheh Abedini, Zahra Hosseini, Masoud Etemadifar and Amin Ghanbarnejad
    Citation: BMC Neurology 2021 21:193
  32. The relationship between the neutrophil-to-lymphocyte ratio (NLR) and poor prognostics in acute ischemic stroke (AIS) patients who receive intravenous thrombolysis (IVT) remains controversial. The purpose of t...

    Authors: Chengbing Wang, Qian Zhang, Mingwei Ji, Jing Mang and Zhongxin Xu
    Citation: BMC Neurology 2021 21:191
  33. The aim of this study was to evaluate the effect of surgical resection and stereotactic biopsy on the complication rate, progression-free survival (PFS) and overall survival (OS) of 70 patients diagnosed at a ...

    Authors: Shiqiang Wu, Junwen Wang, Weihua Liu, Feng Hu, Kai Zhao, Wei Jiang, Ting Lei and Kai Shu
    Citation: BMC Neurology 2021 21:190
  34. There are numerous barriers to identifying patients with silent brain infarcts (SBIs) and white matter disease (WMD) in routine clinical care. A natural language processing (NLP) algorithm may identify patient...

    Authors: Lester Y. Leung, Sunyang Fu, Patrick H. Luetmer, David F. Kallmes, Neel Madan, Gene Weinstein, Vance T. Lehman, Charlotte H. Rydberg, Jason Nelson, Hongfang Liu and David M. Kent
    Citation: BMC Neurology 2021 21:189
  35. Abnormal hypoperfusion on the surgical side after carotid artery stenting is rare. Neurological deterioration caused by it is deceptive, which can easily lead to misdiagnosis. The mechanism of hypoperfusion ha...

    Authors: Zhizhong Yan, Zhonghua Shi, Yuhai Wang, Chunlei Zhang, Huize Liu, Jin Cai and Xin Zhang
    Citation: BMC Neurology 2021 21:188
  36. To date, the genetic contribution to Parkinson’s disease (PD) remains unclear. Mutations in the collagen type VI alpha 3 (COL6A3) gene were recently identified as a cause of isolated dystonia. Since PD and dyston...

    Authors: Chong-Yao Jin, Ran Zheng, Zhi-Hao Lin, Nai-Jia Xue, Ying Chen, Ting Gao, Yi-Qun Yan, Yi Fang, Ya-Ping Yan, Xin-Zhen Yin, Jun Tian, Jia-Li Pu and Bao-Rong Zhang
    Citation: BMC Neurology 2021 21:187
  37. When dizziness/vertigo patients presented with balance disorder, it will bring severe morbidity. There is currently lack of research to explore risk factor related balance disorder in dizziness patients, espec...

    Authors: Zhentang Cao, Cuiting Zhu, Yanan Zhou, Yan Wang, Meimei Chen, Yi Ju and Xingquan Zhao
    Citation: BMC Neurology 2021 21:186
  38. Morvan syndrome (MoS) is a rare autoimmune syndrome associated with antibodies against two kinds of potassium channel proteins, contactin associated protein-like 2 (CASPR2) and leucine-rich glioma inactivated ...

    Authors: Shui-Jing Zhang, Yan-Yan Xue, Hao Yu and Qing-Qing Tao
    Citation: BMC Neurology 2021 21:185

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