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  1. Patients with recent stroke or TIA are at high risk for new vascular events. Several evidence based strategies in secondary prevention of stroke are available but frequently underused. Support programs with mu...

    Authors: Stefanie Leistner, Georg Michelson, Inga Laumeier, Michael Ahmadi, Maureen Smyth, Gabriele Nieweler, Wolfram Doehner, Jan Sobesky, Jochen B Fiebach, Peter Marx, Otto Busse, Friedrich Köhler, Holger Poppert, Martin LJ Wimmer, Thomas Knoll, Paul Von Weitzel-Mudersbach…
    Citation: BMC Neurology 2013 13:11
  2. To improve quality of life (QOL) in patients with multiple sclerosis (MS), it is important to decrease disability and prevent relapse. The aim of this study was to examine the causal and mutual relationships c...

    Authors: Hiromi Kikuchi, Nobuhiro Mifune, Masaaki Niino, Jun-ichi Kira, Tatsuo Kohriyama, Kohei Ota, Masami Tanaka, Hirofumi Ochi, Shunya Nakane and Seiji Kikuchi
    Citation: BMC Neurology 2013 13:10
  3. Jugular venous reflux (JVR) has been reported to cause cough syncope via retrograde-transmitted venous hypertension and consequently decreased cerebral blood flow (CBF). Unmatched frequencies of JVR and cough ...

    Authors: Chih-Ping Chung, Chun-Yu Cheng, Robert Zivadinov, Wei-Chih Chen, Wen-Yung Sheng, Yu-Chin Lee, Han-Hwa Hu, Hung-Yi Hsu and Kuang-Yao Yang
    Citation: BMC Neurology 2013 13:9
  4. POLG1 mutations have been associated with MELAS-like phenotypes. However given several clinical differences it is unknown whether POLG1 mutations are possible causes of MELAS or give raise to a distinct clinical...

    Authors: Antonella Cheldi, Dario Ronchi, Andreina Bordoni, Bianca Bordo, Silvia Lanfranconi, Maria Grazia Bellotti, Stefania Corti, Valeria Lucchini, Monica Sciacco, Maurizio Moggio, Pierluigi Baron, Giacomo Pietro Comi, Antonio Colombo and Anna Bersano
    Citation: BMC Neurology 2013 13:8
  5. Evidence about whether white blood cell (WBC) or its subtypes can act as a biomarker to predict the ischemic stroke events in the general population is scanty, particularly in Asian populations. The aim of thi...

    Authors: Tzy-Haw Wu, Kuo-Liong Chien, Hung-Ju Lin, Hsiu-Ching Hsu, Ta-Chen Su, Ming-Fong Chen and Yuan-Teh Lee
    Citation: BMC Neurology 2013 13:7
  6. Residual disability after stroke is substantial; 65% of patients at 6 months are unable to incorporate the impaired upper extremity into daily activities. Task-oriented training programs are rapidly being adop...

    Authors: Carolee J Winstein, Steven L Wolf, Alexander W Dromerick, Christianne J Lane, Monica A Nelsen, Rebecca Lewthwaite, Sarah Blanton, Charro Scott, Aimee Reiss, Steven Yong Cen, Rahsaan Holley and Stanley P Azen
    Citation: BMC Neurology 2013 13:5
  7. Responsiveness refers to a measurement tool’s ability to detect change in performance over time. The aim of the review was to summarise studies of responsiveness of lower limb physical performance measures dur...

    Authors: Katharine Scrivener, Catherine Sherrington and Karl Schurr
    Citation: BMC Neurology 2013 13:4
  8. A strong inverse relationship of functional limitation and socioeconomic status has been established in western ageing society. Functional limitation can be related to chronic diseases, disuse, cognitive decli...

    Authors: Vorapun Senanarong, Kamolthip Harnphadungkit, Niphon Poungvarin, Sathit Vannasaeng, Samut Chongwisal, Tipa Chakorn, Piyanuch Jamjumrus, Atthapon Raksthaput, Sinisa Chaichanettee, Nattapol Aoonkaew, Suthipol Udompunthurak, Rachelle S Doody and Jeffrey L Cummings
    Citation: BMC Neurology 2013 13:3
  9. It has been suggested that cerebrospinal fluid (CSF) CXCL13 is a diagnostic marker of Lyme neuroborreliosis (LNB), as its levels have been shown to be significantly higher in LNB than in several other CNS infe...

    Authors: Daniel Bremell, Niklas Mattsson, Mikael Edsbagge, Kaj Blennow, Ulf Andreasson, Carsten Wikkelsö, Henrik Zetterberg and Lars Hagberg
    Citation: BMC Neurology 2013 13:2
  10. Fibrates has been extensively used to improve plasma lipid levels and prevent adverse cardiovascular outcomes. However, the effect of fibrates on stroke is unclear at the present time. We therefore carried out...

    Authors: Yu-Hao Zhou, Xiao-Fei Ye, Fei-Fei Yu, Xiao Zhang, Ying-Yi Qin, Jian Lu and Jia He
    Citation: BMC Neurology 2013 13:1
  11. Few studies have systematically addressed the role of epidural analgesia and caesarean delivery in predicting the post-partum disease activity in women with Multiple Sclerosis (MS).

    Authors: Luisa Pastò, Emilio Portaccio, Angelo Ghezzi, Bahia Hakiki, Marta Giannini, Lorenzo Razzolini, Elisa Piscolla, Laura De Giglio, Carlo Pozzilli, Damiano Paolicelli, Maria Trojano, Maria Giovanna Marrosu, Francesco Patti, Loredana La Mantia, Gian Luigi Mancardi, Claudio Solaro…
    Citation: BMC Neurology 2012 12:165
  12. Stroke is one of the major causes of loss of independence, decreased quality of life and mortality among elderly people. About half of the elderly stroke patients discharged after rehabilitation in a nursing h...

    Authors: Tom PMM Vluggen, Jolanda CM van Haastregt, Jeanine A Verbunt, Elly JM Keijsers and Jos MGA Schols
    Citation: BMC Neurology 2012 12:164
  13. Based upon the acquainted loss of dopaminergic neurons in the substantia nigra in Parkinson’s disease (PD), we hypothesised changes in magnetic resonance imaging signal intensities of the basal ganglia to be u...

    Authors: Sarah Jesse, Jan Kassubek, Hans-Peter Müller, Albert C Ludolph and Alexander Unrath
    Citation: BMC Neurology 2012 12:163
  14. Reduced upper extremity function is one of the most common impairments after stroke and has previously been reported in approximately 70-80% of patients in the acute stage. Acute care for stroke has changes ov...

    Authors: Hanna C Persson, Marina Parziali, Anna Danielsson and Katharina S Sunnerhagen
    Citation: BMC Neurology 2012 12:162
  15. Physical disability in multiple sclerosis (MS) is frequently characterized by impaired ambulation. Although walking tests have been successfully employed to assess walking ability in MS patients, data analytic...

    Authors: Janina M Burschka, Philipp M Keune, Uwe Menge, Ulrich Hofstadt-van Oy, Patrick Oschmann and Olaf Hoos
    Citation: BMC Neurology 2012 12:161
  16. This paper provides a strategy to obtain a reliable estimate of the incidence rate for Amyotrophic lateral sclerosis based on data from the National Registry of Rare Diseases (NRRD). In fact, unobserved cases ...

    Authors: Irene Rocchetti, Domenica Taruscio and Daniela Pierannunzio
    Citation: BMC Neurology 2012 12:160
  17. Nerve damage in leprosy often causes disabilities and deformities. Prednisolone is used to treat nerve function impairment (NFI). However, optimal dose and duration of prednisolone treatment has not been estab...

    Authors: Inge Wagenaar, Wim Brandsma, Erik Post, Wim van Brakel, Diana Lockwood, Peter Nicholls, Paul Saunderson, Cairns Smith, Einar Wilder-Smith and Jan Hendrik Richardus
    Citation: BMC Neurology 2012 12:159
  18. Recombinant factor VIIa (rFVIIa) may be used for rapid hemostasis in life-threatening hemorrhage. In warfarin-associated intracerebral hemorrhage (wICH), FVIIa use is controversial and may carry significant th...

    Authors: Chou Sherry H-Y, Cai Xuemei, Konigsberg Rachael G, Bresette Linda M, Henderson Galen V, Sorond Farzaneh A and Feske Steven K
    Citation: BMC Neurology 2012 12:158
  19. Many Polio survivors have reduced mobility, pain and fatigue, which make access to conventional forms of aerobic exercise difficult. Inactivity leads to increased risk of health problems, many of which are pre...

    Authors: Deirdre Murray, Dara Meldrum, Roisin Moloney, Anna Campion, Frances Horgan and Orla Hardiman
    Citation: BMC Neurology 2012 12:157
  20. Behavioral changes in patients with amyotrophic lateral sclerosis (ALS) mirror those found in frontotemporal dementia (FTD). Considering the high rate of neuropsychiatric symptoms found in ALS patients, this p...

    Authors: Patricia Lillo, Eneida Mioshi and John R Hodges
    Citation: BMC Neurology 2012 12:156
  21. To explore current status and choices regarding diagnosis and treatment of Parkinson’s disease (PD) among physicians, general neurologists and movement disorders specialists in China via a national survey.

    Authors: Wei Chen, Shuai Chen, Qin Xiao, Gang Wang and Sheng-Di Chen
    Citation: BMC Neurology 2012 12:155
  22. In patients with relapsing–remitting multiple sclerosis (RRMS), subcutaneous (sc) interferon (IFN)β-1a and IFNβ-1b have been shown to reduce relapse rates. A formulation of IFNβ-1a has been produced without fe...

    Authors: Barry Singer, Daniel Bandari, Mark Cascione, Christopher LaGanke, John Huddlestone, Randy Bennett and Fernando Dangond
    Citation: BMC Neurology 2012 12:154
  23. Establishing a confident clinical diagnosis before an advanced stage of illness can be difficult in Creutzfeldt-Jakob disease (CJD) but unlike common causes of dementia, prion diseases can often be diagnosed b...

    Authors: Christopher Carswell, Andrew Thompson, Ana Lukic, John Stevens, Peter Rudge, Simon Mead, John Collinge and Harpreet Hyare
    Citation: BMC Neurology 2012 12:153
  24. Posterior reversible encephalopathy syndrome (PRES) has been increasingly identified in patients with systemic lupus erythematosus (SLE) owing to the advance in neuroimaging techniques. Prompt diagnosis is piv...

    Authors: Bin Liu, Xuan Zhang, Feng-chun Zhang, Yuan Yao, Ri-zhi Zhou, Miao-Miao Xin and Li-Qin Wang
    Citation: BMC Neurology 2012 12:152
  25. Little is known about the long-term success of non-drug therapies for treating dementia, especially whether the effects are sustained after therapy ends. Here, we examined the effects of a one-year multimodal ...

    Authors: Katharina Luttenberger, Benjamin Hofner and Elmar Graessel
    Citation: BMC Neurology 2012 12:151
  26. As low and middle-income countries such as Vietnam experience the health transition from infectious to chronic diseases, the morbidity and mortality from stroke will rise. In line with the recommendation of th...

    Authors: David L Tirschwell, Thanh G N Ton, Kiet A Ly, Quang Van Ngo, Tung T Vo, Chien Hung Pham, William T Longstreth Jr and Annette L Fitzpatrick
    Citation: BMC Neurology 2012 12:150
  27. The purpose of this study was to examine associations between cardiovascular risk factors and cognitive ability in middle aged and elderly Lithuanian urban population.

    Authors: Abdonas Tamosiunas, Migle Baceviciene, Regina Reklaitiene, Ricardas Radisauskas, Kristina Jureniene, Adelina Azaraviciene, Dalia Luksiene, Vilija Malinauskiene, Evelina Daugeliene and Laura Sapranaviciute-Zabazlajeva
    Citation: BMC Neurology 2012 12:149
  28. Autism spectrum disorders (ASD) are associated with widespread alterations in white matter (WM) integrity. However, while a growing body of studies is shedding light on microstructural WM alterations in high-f...

    Authors: Lucia Billeci, Sara Calderoni, Michela Tosetti, Marco Catani and Filippo Muratori
    Citation: BMC Neurology 2012 12:148
  29. The burden of cognitive impairment among school children from developing communities is under reported due to lack of culturally appropriate screening tools. The objective of this study was to validate a cultu...

    Authors: Gwendoline Q Kandawasvika, Paul M Mapingure, Margaret Nhembe, Richard Mtereredzi and Babill Stray-Pedersen
    Citation: BMC Neurology 2012 12:147
  30. To investigate to what extent Alzheimer's Disease (AD) affects Resting State activity, the possible impairment of independent electrophysiological parameters was determined in Eye-open and Eye-closed Condition...

    Authors: Antonio Tartaglione, Luciano Spadavecchia, Marco Maculotti and Fabio Bandini
    Citation: BMC Neurology 2012 12:145
  31. We report a female patient with familial Creutzfeldt-Jakob disease with V180I mutation (fCJD with V180I), who was serially followed up with magnetic resonance imaging (MRI) and electroencephalogram (EEG) for u...

    Authors: Kentaro Deguchi, Motonori Takamiya, Shoko Deguchi, Nobutoshi Morimoto, Tomoko Kurata, Yoshio Ikeda and Koji Abe
    Citation: BMC Neurology 2012 12:144
  32. Reduction of retinal nerve fibre layer (RNFL) thickness was shown as part of the neurodegenerative process in a range of different neurodegenerative pathologies including Alzheimer′s disease (AD), idiopathic P...

    Authors: Sarah Wiethoff, Ahmad Zhour, Ludger Schöls and Manuel Dominik Fischer
    Citation: BMC Neurology 2012 12:143
  33. Stroke represents one of the most costly and long-term disabling conditions in adulthood worldwide and there is a need to determine the effectiveness of rehabilitation programs in the late phase after stroke. ...

    Authors: Lina Bunketorp Käll, Åsa Lundgren-Nilsson, Christian Blomstrand, Marcela Pekna, Milos Pekny and Michael Nilsson
    Citation: BMC Neurology 2012 12:141
  34. The autophagic vacuolar myopathies (AVM) are a group of inherited myopathies defined by the presence of autophagic vacuoles in pathological muscle specimens. AVM can be categorized into three groups: acid malt...

    Authors: Kota Bokuda, Keizo Sugaya, Shunichiro Tamura, Kazuhito Miyamoto, Shiro Matsubara and Takashi Komori
    Citation: BMC Neurology 2012 12:140
  35. Acute symptomatic hypoglycaemia is a differential diagnosis in patients presenting with stroke-like neurological impairment, but few textbooks describe the full brain imaging appearances. We systematically rev...

    Authors: Ai Wain Yong, Zoe Morris, Kirsten Shuler, Colin Smith and Joanna Wardlaw
    Citation: BMC Neurology 2012 12:139
  36. It remains unclear how executive function (EF) is affected in the stage of amnestic mild cognitive impairment (aMCI). Previous studies using different methods to assess EF in patients with aMCI have reached in...

    Authors: Dongming Zheng, Xiaoyu Dong, Hongzan Sun, Yongchuan Xu, Ying Ma and Xiaoming Wang
    Citation: BMC Neurology 2012 12:138
  37. The aim of this study was to estimate the one-year societal costs due to a stroke event in Italy and to investigate variables associated with costs in different phases following hospital admission.

    Authors: Giovanni Fattore, Aleksandra Torbica, Alessandra Susi, Aguzzi Giovanni, Giancarlo Benelli, Marianna Gozzo and Vito Toso
    Citation: BMC Neurology 2012 12:137
  38. The Hopkins Verbal Learning Test (HVLT) has been validated for detecting dementia in English-speaking populations. However, no studies have examined the Chinese version of the HVLT scale, and appropriate cut-o...

    Authors: Jing Shi, Jinzhou Tian, Mingqing Wei, Yingchun Miao and Yongyan Wang
    Citation: BMC Neurology 2012 12:136
  39. Ischemic stroke by septic embolism occurs primarily in the context of infective endocarditis or in patients with a right-to-left shunt and formation of a secondary cerebral abscess is a rare event. Erosion of ...

    Authors: Philipp Albrecht, Mark Stettner, Leila Husseini, Stephan Macht, Sebastian Jander, Colin Mackenzie, Ulrike Oesterlee, Philipp Slotty, Axel Methner, Hans-Peter Hartung and Orhan Aktas
    Citation: BMC Neurology 2012 12:133
  40. We tested the hypothesis that in patients with occlusion of the terminal internal carotid artery and/or the proximal middle cerebral artery, a diffusion abnormality of 70 ml or less is accompanied by a diffusi...

    Authors: Reza Hakimelahi, Albert J Yoo, Julian He, Lee H Schwamm, Michael H Lev, Pamela W Schaefer and Ramon Gilberto González
    Citation: BMC Neurology 2012 12:132
  41. Multiple system atrophy (MSA) is a progressive neurodegenerative disorder of unknown etiology, manifesting as combination of parkinsonism, cerebellar syndrome and dysautonomia. Disease-modifying therapies are ...

    Authors: Peter Novak, Arlene Williams, Paula Ravin, Omar Zurkiya, Amir Abduljalil and Vera Novak
    Citation: BMC Neurology 2012 12:131
  42. The recent SLEEMSA study that evaluated excessive daytime sleepiness (EDS) in Caucasian patients with multiple system atrophy (MSA) demonstrated that EDS was more frequent in patients (28%) than in healthy sub...

    Authors: Takayoshi Shimohata, Hideaki Nakayama, Masahiko Tomita, Tetsutaro Ozawa and Masatoyo Nishizawa
    Citation: BMC Neurology 2012 12:130
  43. Community ambulation is a highly complex skill requiring the ability to adapt to increased environmental complexity and perform multiple tasks simultaneously. After stroke, individuals demonstrate a diminished...

    Authors: Prudence Plummer-D’Amato, Anastasia Kyvelidou, Dagmar Sternad, Bijan Najafi, Raymond M Villalobos and David Zurakowski
    Citation: BMC Neurology 2012 12:129
  44. To examine the effects of a multicomponent exercise program on the cognitive function of older adults with amnestic mild cognitive impairment (aMCI).

    Authors: Takao Suzuki, Hiroyuki Shimada, Hyuma Makizako, Takehiko Doi, Daisuke Yoshida, Kota Tsutsumimoto, Yuya Anan, Kazuki Uemura, Sangyoon Lee and Hyuntae Park
    Citation: BMC Neurology 2012 12:128
  45. Both severe stenosis and completed occlusion in internal carotid artery or its distal branches have been considered the main reasons of cerebral hypoperfusion, which contributes to the washout disturbances of emb...

    Authors: Junliang Han, Fang Yang, Wenrui Jiang, Guangyun Zhang, Zhirong Liu, Xuedong Liu, Feng Xia, Ya Bai, Junhong He, Manxiang Chao and Gang Zhao
    Citation: BMC Neurology 2012 12:127

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