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  1. Evidence exist that motor observation activates the same cortical motor areas that are involved in the performance of the observed actions. The so called “mirror neuron system” has been proposed to be responsi...

    Authors: Denis Ertelt, Claudia Hemmelmann, Christian Dettmers, Andreas Ziegler and Ferdinand Binkofski
    Citation: BMC Neurology 2012 12:42
  2. Certain immune-mediated diseases (IMDs) have been associated with increased risk for cardiovascular disorders. The aim of the present study was to examine whether there is an association between 32 different I...

    Authors: Bengt Zöller, Xinjun Li, Jan Sundquist and Kristina Sundquist
    Citation: BMC Neurology 2012 12:41
  3. Hyperintense putaminal rim (HPR) is an important magnetic resonance imaging (MRI) sign for multiple system atrophy (MSA). Recent studies have suggested that it can also be observed in normal subjects at 3 T. W...

    Authors: Khin K Tha, Satoshi Terae, Akiko Tsukahara, Hiroyuki Soma, Ryo Morita, Ichiro Yabe, Yoichi M Ito, Hidenao Sasaki and Hiroki Shirato
    Citation: BMC Neurology 2012 12:39
  4. Alzheimer’s disease (AD) is the most common form of dementia. Mutations in genes such as those encoding amyloid precursor protein (APP), presenilin 1 and presenilin 2, are responsible for early-onset familial AD.

    Authors: Masao Abe, Naomi Sonobe, Ryuji Fukuhara, Yoko Mori, Shinichiro Ochi, Teruhisa Matsumoto, Takaaki Mori, Satoshi Tanimukai and Shu-ichi Ueno
    Citation: BMC Neurology 2012 12:38
  5. Treatment options for patients suffering from progressive forms of multiple sclerosis (MS) remain inadequate. Mast cells actively participate in the pathogenesis of MS, in part because they release large amoun...

    Authors: Patrick Vermersch, Rabah Benrabah, Nicolas Schmidt, Hélène Zéphir, Pierre Clavelou, Cyrille Vongsouthi, Patrice Dubreuil, Alain Moussy and Olivier Hermine
    Citation: BMC Neurology 2012 12:36
  6. We report the case of a chronic stroke patient (62 months after injury) showing total absence of motor activity evoked by transcranial magnetic stimulation (TMS) of spared regions of the left motor cortex, but...

    Authors: Julià L Amengual, Antoni Valero-Cabré, Misericordia Veciana de las Heras, Nurja Rojo, Seán Froudist-Walsh, Pablo Ripollés, Nils Bodammer, Bahram Mohammadi, Jordi Montero, Carles Grau, Thomas F Münte and Antoni Rodríguez-Fornells
    Citation: BMC Neurology 2012 12:35
  7. Spontaneous intracerebral hemorrhage is a disease with high morbidity, high disability rate, high mortality, and high economic burden. Whether patients can benefit from surgical evacuation of hematomas is stil...

    Authors: Xin Zan, Hao Li, Wenke Liu, Yuan Fang, Junpeng Ma, Zhigang Lan, Xi Li, Xin Liu and Chao You
    Citation: BMC Neurology 2012 12:34
  8. Identification of causes of dementia soon after symptom onset is important, because appropriate treatment of some causes of dementia can slow or halt its progression or enable symptomatic treatment where appro...

    Authors: Rebecca Beynon, Jonathan A C Sterne, Gordon Wilcock, Marcus Likeman, Roger M Harbord, Margaret Astin, Margaret Burke, Alysson Bessell, Yoav Ben-Shlomo, James Hawkins, William Hollingworth and Penny Whiting
    Citation: BMC Neurology 2012 12:33
  9. Vasospasm-related delayed cerebral ischemia (DCI) significantly impacts on outcome after aneurysmal subarachnoid hemorrhage (SAH). Erythropoietin (EPO) may reduce the severity of cerebral vasospasm and improve...

    Authors: Raimund Helbok, Ehab Shaker, Ronny Beer, Andreas Chemelli, Martin Sojer, Florian Sohm, Gregor Broessner, Peter Lackner, Monika Beck, Alexandra Zangerle, Bettina Pfausler, Claudius Thome and Erich Schmutzhard
    Citation: BMC Neurology 2012 12:32
  10. Kleine-Levin syndrome is a rare sleep disorder of unknown etiology. It is characterized by intermittent periods of excessive sleepiness, cognitive disturbances and behavioral abnormalities. Nine cases of famil...

    Authors: Taro Ueno, Akira Fukuhara, Azusa Ikegami, Fumihiro Ohishi and Kazuhiko Kume
    Citation: BMC Neurology 2012 12:31
  11. Current standard therapy for seizure prophylaxis in Neuro-surgical patients involves the use of Phenytoin (PHY). However, a new drug Levetiracetam (LEV) is emerging as an alternate treatment choice. We aimed t...

    Authors: Syed Nabeel Zafar, Abdul Ahad Khan, Asfar Ayaz Ghauri and Muhammad Shahzad Shamim
    Citation: BMC Neurology 2012 12:30
  12. Best current estimates of neuropathic pain (NeuP) prevalence come from studies using various screening detecting pain with probable neuropathic features; the proportion experiencing significant, long-term NeuP...

    Authors: Blair H Smith, Nicola Torrance, Janice A Ferguson, Michael I Bennett, Michael G Serpell and Kate M Dunn
    Citation: BMC Neurology 2012 12:29
  13. Fatigue in combination with gait and balance impairments can severely limit daily activities in people with multiple sclerosis (PWMS). Generalised fatigue has a major impact on walking ability, with moderately...

    Authors: James McLoughlin, Christopher Barr, Daina Sturnieks, Stephen Lord and Maria Crotty
    Citation: BMC Neurology 2012 12:27
  14. Chronic cerebrospinal venous insufficiency (CCSVI) is a vascular condition characterized by anomalies of the primary veins outside the skull that has been reported to be associated with MS. In the blinded Comb...

    Authors: Bianca Weinstock-Guttman, Murali Ramanathan, Karen Marr, David Hojnacki, Ralph HB Benedict, Charity Morgan, Eluen Ann Yeh, Ellen Carl, Cheryl Kennedy, Justine Reuther, Christina Brooks, Kristin Hunt, Makki Elfadil, Michelle Andrews and Robert Zivadinov
    Citation: BMC Neurology 2012 12:26
  15. The olfactory bulb (OB) receives extensive cholinergic input from the basal forebrain and is affected very early in Alzheimer’s disease (AD). We speculated that an olfactory ‘stress test’ (OST), targeting the ...

    Authors: Peter W Schofield, Houman Ebrahimi, Alison L Jones, Grant A Bateman and Sonya R Murray
    Citation: BMC Neurology 2012 12:24
  16. Previous studies have reported white matter (WM) brain alterations in asymptomatic patients with human immunodeficiency virus (HIV).

    Authors: Bianca Stubbe-Drger, Michael Deppe, Siawoosh Mohammadi, Simon S Keller, Harald Kugel, Nora Gregor, Stefan Evers, Peter Young, E-Bernd Ringelstein, Gabriele Arendt, Stefan Knecht and Ingo W Husstedt
    Citation: BMC Neurology 2012 12:23
  17. Distal myopathy with rimmed vacuoles/hereditary inclusion body myopathy is clinically characterized by the early involvement of distal leg muscles. The striking pathological features of the myopathy are muscle...

    Authors: Akihiko Hoshi, Teiji Yamamoto, Saeko Kikuchi, Tomoko Soeda, Keiko Shimizu and Yoshikazu Ugawa
    Citation: BMC Neurology 2012 12:22
  18. Loss of arm-hand performance due to a hemiparesis as a result of stroke or cerebral palsy (CP), leads to large problems in daily life of these patients. Assessment of arm-hand performance is important in both ...

    Authors: Ryanne JM Lemmens, Annick AA Timmermans, Yvonne JM Janssen-Potten, Rob JEM Smeets and Henk AM Seelen
    Citation: BMC Neurology 2012 12:21
  19. The α2-adrenoreceptor agonist dexmedetomidine is known to provide neuroprotection under ischemic conditions. In this study we investigated whether dexmedetomidine has a protective effect in an in vitro model for ...

    Authors: Marc Schoeler, Philip D Loetscher, Rolf Rossaint, Astrid V Fahlenkamp, Georg Eberhardt, Steffen Rex, Joachim Weis and Mark Coburn
    Citation: BMC Neurology 2012 12:20
  20. People with Multiple Sclerosis (MS) frequently experience balance and mobility impairments, including reduced trunk stability. Pilates-based core stability training, which is aimed at improving control of the ...

    Authors: Jennifer Freeman, Esther Fox, Margaret Gear and Alan Hough
    Citation: BMC Neurology 2012 12:19
  21. Annually, some 9000 people in Switzerland suffer a first time stroke. Of these 60% are left with moderate to severe walking disability. Evidence shows that rehabilitation techniques which emphasise activity of...

    Authors: Clare Maguire, Judith M Sieben, Florian Erzer, Beat Goepfert, Matthias Frank, Georg Ferber, Melissa Jehn, Arno Schmidt-Trucksäss and Robert A de Bie
    Citation: BMC Neurology 2012 12:18
  22. The aim of this paper is to examine factors associated with discharge destination after acquired brain injury in a publicly insured population using the Anderson Behavioral Model as a framework.

    Authors: Amy Y Chen, Brandon Zagorski, Daria Parsons, Rika Vander Laan, Vincy Chan and Angela Colantonio
    Citation: BMC Neurology 2012 12:16
  23. Temporal lobe epilepsy (TLE) is a common form of focal epilepsy. Serum biomarkers to predict cognitive performance in TLE patients without psychiatric comorbidities and the link with gray matter (GM) atrophy h...

    Authors: Chiung-Chih Chang, Chun-Chung Lui, Chen-Chang Lee, Shang-Der Chen, Wen-Neng Chang, Cheng-Hsien Lu, Nai-Ching Chen, Alice Y W Chang, Samuel H H Chan and Yao-Chung Chuang
    Citation: BMC Neurology 2012 12:15
  24. Computer tomography (CT) is still the fastest and most robust technique to rule out ICH in acute stroke. However CT-sensitivity for detection of ischemic stroke in the hyperacute phase is still relatively low....

    Authors: Carolin Knauer, Katharina Knauer, Susanne Müller, Albert C Ludolph, Dietmar Bengel, Hans P Müller and Roman Huber
    Citation: BMC Neurology 2012 12:14
  25. A substantial fraction of Parkinson's disease patients deteriorate during hospitalisation, but the precise proportion and the reasons why have not been studied systematically and the focus has been on surgical...

    Authors: Oliver HH Gerlach, Martijn PG Broen, Peter HMF van Domburg, Ad J Vermeij and Wim EJ Weber
    Citation: BMC Neurology 2012 12:13
  26. Hyperechogenicity of the substantia nigra (SN+), detected by transcranial sonography (TCS), was reported as a characteristic finding in Parkinson's disease (PD), with high diagnostic accuracy values, when comp...

    Authors: Kristina Laučkaitė, Daiva Rastenytė, Danguolė Šurkienė, Antanas Vaitkus, Andrius Sakalauskas, Arūnas Lukoševičius and Rymantė Gleiznienė
    Citation: BMC Neurology 2012 12:12
  27. Traditionally, multiple sclerosis has been viewed as a disease predominantly affecting white matter. However, this view has lately been subject to numerous changes, as new evidence of anatomical and histologic...

    Authors: Dana Horakova, Tomas Kalincik, Jana Blahova Dusankova and Ondrej Dolezal
    Citation: BMC Neurology 2012 12:10
  28. Clinical characteristics and patterns of healthcare utilization in patients with painful neuropathic disorders (PNDs) who are under the care of general practitioners (GPs) in the UK are not well understood.

    Authors: Ariel Berger, Alesia Sadosky, Ellen Dukes, John Edelsberg and Gerry Oster
    Citation: BMC Neurology 2012 12:8
  29. Achieving good adherence to self-injected treatments for multiple sclerosis can be difficult. Injection devices may help to overcome some of the injection-related barriers to adherence that can be experienced ...

    Authors: Alessandra Lugaresi, Ciro Florio, Vincenzo Brescia-Morra, Salvatore Cottone, Paolo Bellantonio, Marinella Clerico, Diego Centonze, Antonio Uccelli, Maria di Ioia, Giovanna De Luca, Andrea Marcellusi and Andrea Paolillo
    Citation: BMC Neurology 2012 12:7
  30. Researchers have recently advocated for the 2-minute walk (2MW) as an alternative for the 6-minute walk (6MW) to assess long distance ambulation in persons with multiple sclerosis (MS). This recommendation has...

    Authors: Robert W Motl, Yoojin Suh, Swathi Balantrapu, Brian M Sandroff, Jacob J Sosnoff, John Pula, Myla D Goldman and Bo Fernhall
    Citation: BMC Neurology 2012 12:6
  31. The basal ganglia (BG) are thought to play an important role in the control of eye movements. Accordingly, the broad variety of subtle oculomotor alterations that has been described in Parkinson's disease (PD)...

    Authors: Elmar H Pinkhardt, Reinhart Jürgens, Dorothée Lulé, Johanna Heimrath, Albert C Ludolph, Wolfgang Becker and Jan Kassubek
    Citation: BMC Neurology 2012 12:5
  32. This paper describes the rationale and design of the ENVIS-ion Study, which aims to determine whether low-dose aspirin reduces the development of white matter hyper-intense (WMH) lesions and silent brain infar...

    Authors: Christopher M Reid, Elsdon Storey, Tien Y Wong, Robyn Woods, Andrew Tonkin, Jie Jin Wang, Anthony Kam, Andrew Janke, Rowan Essex, Walter P Abhayaratna and Marc M Budge
    Citation: BMC Neurology 2012 12:3
  33. Previous cost-effectiveness studies of cholinesterase inhibitors have modeled Alzheimer's disease (AD) progression and treatment effects through single or global severity measures, or progression to "Full Time...

    Authors: Susanne Hartz, Denis Getsios, Sunning Tao, Steve Blume and Grant Maclaine
    Citation: BMC Neurology 2012 12:2
  34. Supine recumbence has been widely performed to prevent post-lumbar puncture headache (PLPH). However, the optimal duration of supine recumbence is controversial. The aim of the study is to compare the occurren...

    Authors: Sung R Kim, Hyun S Chae, Mi J Yoon, Jung H Han, Kwang J Cho and Sun J Chung
    Citation: BMC Neurology 2012 12:1
  35. Progressive supranuclear palsy (PSP) and parkinsonian variant of multiple system atrophy (MSA-P) are clinically difficult to differentiate from idiopathic Parkinson's disease (PD), particularly in the early st...

    Authors: Masahiko Suzuki, Masaya Hashimoto, Masayuki Yoshioka, Maiko Murakami, Keiichi Kawasaki and Mitsuyoshi Urashima
    Citation: BMC Neurology 2011 11:157
  36. Glutamic acid decarboxylase (GAD) is the rate-limiting enzyme for producing γ-aminobutyric acid, and it has been suggested that antibodies against GAD play a role in neurological conditions and type 1 diabetes...

    Authors: Masahito Takagi, Hiroshi Yamasaki, Keiko Endo, Tetsuya Yamada, Keizo Kaneko, Yoshitomo Oka and Etsuro Mori
    Citation: BMC Neurology 2011 11:156
  37. There are a lack of biomarkers which can be used to predict clinical outcomes for multiple sclerosis (MS) patients receiving interferon beta (IFN-β). Thus the objective of this study was to characterize change...

    Authors: Jennifer M Kress-Bennett, Garth D Ehrlich, Ashley Bruno, J Christopher Post, Fen Z Hu and Thomas F Scott
    Citation: BMC Neurology 2011 11:155
  38. The intracranial localization of large artery disease is recognized as the main cause of ischemic stroke in the world, considering all countries, although its global burden is widely underestimated. Indeed it ...

    Authors: Giovanni Malferrari, Marialuisa Zedde, Gianni De Berti, Massimo Maggi and Norina Marcello
    Citation: BMC Neurology 2011 11:154
  39. A detailed behavioral profile associated with focal congenital malformation of the ventromedial prefrontal cortex (vmPFC) has not been reported previously. Here we describe a 14 year-old boy, B.W., with neurol...

    Authors: Aaron D Boes, Amanda Hornaday Grafft, Charuta Joshi, Nathaniel A Chuang, Peg Nopoulos and Steven W Anderson
    Citation: BMC Neurology 2011 11:151
  40. Children diagnosed with spastic Cerebral Palsy (CP) often show perceptual and cognitive problems, which may contribute to their functional deficit. Here we investigated if altered ability to determine whether ...

    Authors: Anina Ritterband-Rosenbaum, Mark S Christensen, Mette Kliim-Due, Line Z Petersen, Betina Rasmussen and Jens B Nielsen
    Citation: BMC Neurology 2011 11:150
  41. Anti-N-methyl-D-aspartate receptor encephalitis is an increasingly common autoimmune disorder mediated by antibodies to certain subunit of the N-methyl-D-aspartate receptor. Recent literatures have described a...

    Authors: Chun-Ling Xu, Lei Liu, Wei-Qin Zhao, Ji-Mei Li, Rui-Jin Wang, Shu-Hui Wang, De-Xin Wang, Mei-Yun Liu, Shan-Shan Qiao and Jia-Wei Wang
    Citation: BMC Neurology 2011 11:149

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