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  1. Early stage neuromyelitis optica spectrum disorders (NMOSD) with non-opticospinal manifestations as initial symptoms are easily misdiagnosed; however, data on the full symptom profile are limited. Moreover, th...

    Authors: Rui Li, Danli Lu, Hao Li, Yuge Wang, Yaqing Shu, Yanyu Chang, Xiaobo Sun, Zhengqi Lu, Wei Qiu and Zhi Yang
    Citation: BMC Neurology 2021 21:35
  2. The communication of a life-changing diagnosis can be a difficult task for doctors with potential long-term effects on patient outcomes. Although several studies have addressed the experiences of individuals w...

    Authors: Eleftherios Anestis, Fiona J. R. Eccles, Ian Fletcher and Jane Simpson
    Citation: BMC Neurology 2021 21:34
  3. Internal carotid artery (ICA) stenosis has been recently reported to cause hemichorea, mainly in East Asia. The East Asian-specific p.R4810K variant of RNF213, a susceptibility gene for moyamoya disease (MMD), ac...

    Authors: Satoshi Hosoki, Takeshi Yoshimoto and Masafumi Ihara
    Citation: BMC Neurology 2021 21:32
  4. Hypothyroidism (HT) and carotid artery stenosis (CAS) are complications of radiotherapy (RT) in patients with head and neck cancer (HNC). The impact of post-RT HT on CAS progression remains unclear.

    Authors: Chi-Hung Liu, Joseph Tung-Chieh Chang, Tsong-Hai Lee, Pi-Yueh Chang, Chien-Hung Chang, Hsiu-Chuan Wu, Ting-Yu Chang, Kuo-Lun Huang, Chien-Yu Lin, Kang-Hsing Fan and Yeu-Jhy Chang
    Citation: BMC Neurology 2021 21:30
  5. Symplastic hemangioma is a benign superficial abnormal buildup of blood vessels, with morphological features which can mimic a pseudo malignancy. A few cases have been reported in the literature. We report her...

    Authors: Najwa Abdalkabeer A. Bantan, Ahmed H. Abouissa, Muhammad Saeed, Mustafa Hassan Alwalily, Kamal Bakour Balkhoyour, Khalid Mohammad Ashour, Amal Ali Hassan, Afnan Hisham Falemban and Mohiuddin M. Taher
    Citation: BMC Neurology 2021 21:29
  6. Abnormal eye movements are common in spinocerebellar ataxias Type 3 (SCA3). We conducted the research to explore the frequency of abnormal eye movements in Chinese patients with SCA3, to compare the demographi...

    Authors: Junyu Lin, Lingyu Zhang, Bei Cao, Qianqian Wei, Ruwei Ou, Yanbing Hou, Xinran Xu, Kuncheng Liu, Xiaojing Gu and Huifang Shang
    Citation: BMC Neurology 2021 21:28
  7. This observational study was performed to show the impact of complications and interventions during neurocritical care on the outcome after aneurysmal subarachnoid hemorrhage (SAH).

    Authors: Alexander Hammer, Frank Erbguth, Matthias Hohenhaus, Christian M. Hammer, Hannes Lücking, Markus Gesslein, Monika Killer-Oberpfalzer, Hans-Herbert Steiner and Hendrik Janssen
    Citation: BMC Neurology 2021 21:27
  8. To investigate the feasibility of intracranial pressure (ICP) monitoring after traumatic brain injury (TBI) by electromagnetic coupling phase sensing, we established a portable electromagnetic coupling phase s...

    Authors: Gen Li, Wang Li, Jingbo Chen, Shuanglin Zhao, Zelin Bai, Qi Liu, Qi Liao, Minglian He, Wei Zhuang, Mingsheng Chen, Jian Sun and Yujie Chen
    Citation: BMC Neurology 2021 21:26
  9. Meningiomas are the most common benign intracranial tumors, and commonly comprise high-vascularizing but slow-growing tumors. On the other hand, meningiomas arising from the ventricular system are of rare occu...

    Authors: Koichiro Sumi, Takeshi Suma, Reona Yoshida, Ryuta Kajimoto, Masato Kobayashi, Takamichi Katsuhara, Koki Hirayama, Xiaoyan Tang, Naoki Otani and Atsuo Yoshino
    Citation: BMC Neurology 2021 21:25
  10. Stroke is a major health problem around the world. Several studies have examine the influence of ambient temperature on incidence of stoke, but they reported different results for different types of stroke and...

    Authors: Mirjam Ravljen, Fajko Bajrović and Damjan Vavpotič
    Citation: BMC Neurology 2021 21:23
  11. Increasing evidences have showed that neuroimaging markers of SVD can predict the short-term outcome of acute ischemic stroke (AIS). It is unclear that whether neuroimaging markers of SVD are also associated w...

    Authors: Xuemei Chen, Lin Wang, Junying Jiang, Yuanyuan Gao, Rui Zhang, Xiaoyuan Zhao, Tingwen Shen, Qi Dai and Junrong Li
    Citation: BMC Neurology 2021 21:21
  12. The prevalence of carotid artery stenosis (CAS) in acute ischaemic stroke (AIS) patients is historically reported at 15–20%, but an up-to-date estimate is lacking. We hypothesise it is lower than historically ...

    Authors: Twan J van Velzen, Laurien S Kuhrij, Willeke F Westendorp, Diederik van de Beek and Paul J Nederkoorn
    Citation: BMC Neurology 2021 21:20
  13. Residual motor deficits of the upper limb in patients with chronic stroke are common and have a negative impact on autonomy, participation and quality of life. Music-Supported Therapy (MST) is an effective int...

    Authors: Jennifer Grau-Sánchez, Emma Segura, David Sanchez-Pinsach, Preeti Raghavan, Thomas F. Münte, Anna Marie Palumbo, Alan Turry, Esther Duarte, Teppo Särkämö, Jesus Cerquides, Josep Lluis Arcos and Antoni Rodríguez-Fornells
    Citation: BMC Neurology 2021 21:19
  14. Dorsolateral medullary infarction is a typical cerebral infarction which is characterized by Wallenberg’s syndrome. Neurotrophic keratopathy is an uncommon consequence of dorsolateral medullary infarction. At ...

    Authors: Jing Wang, Pei Liu, Zhongzhong Liu, Ye Tian, Guilian Zhang, Jun Guo, Li Li, Zhiqin Liu, Zucheng Han, Wenjuan Lin, Xuemei Lin, Qingli Lu, Yan Liu, Qiaoqiao Chang and Songdi Wu
    Citation: BMC Neurology 2021 21:18
  15. Glucocerebrosidase (GBA) heterozygous variants are the most important genetic risk factor for the development of alpha-synucleinopathies (i.e., Parkinson’s disease and Dementia with Lewy Bodies). Herein, we repor...

    Authors: Marina Picillo, Sara Scannapieco, Alessandro Iavarone, Monia Ginevrino, Enza Maria Valente and Paolo Barone
    Citation: BMC Neurology 2021 21:17
  16. Parkinson’s disease (PD), frequently accompanied by cognitive impairments, is associated with systemic oxidative stress and abnormal structural changes on brain images. We aimed to identify the correlation bet...

    Authors: Ta-Chih Chang, Yi-Cun Chen, Yu-Chi Huang, Wei-Che Lin and Cheng-Hsien Lu
    Citation: BMC Neurology 2021 21:16
  17. Vascular Parkinsonism(VaP) is defined as parkinsonism resulting from cerebral vascular disease(CVD), with presence of variable motor and non-motor signs that are corroborated by clinical, anatomic or imaging f...

    Authors: Shouzi Zhang, Yuanyuan Wang, Lixin Liu, Li Zhang, Li Ma, Haiyan Wu, Xuelin He, Mingwei Zhu, Luning Wang and Fan Mei
    Citation: BMC Neurology 2021 21:15
  18. Adenomyosis, a benign gynecological disease, causes cerebral infarction. Similar to Trousseau’s syndrome, it elevates cancer antigen 125 (CA125) and D-dimer levels; causes hypercoagulability; and results in ce...

    Authors: Ryo Aiura, Sadayoshi Nakayama, Hroo Yamaga, Yu Kato and Hirotake Fujishima
    Citation: BMC Neurology 2021 21:14
  19. Dystrophinopathies are the most common type of inherited muscular diseases. Muscle biopsy and genetic tests are effective to diagnose the disease but cost much more than primary hospitals can reach. The more a...

    Authors: Mei Yang, Yiming Zheng, Zhiying Xie, Zhaoxia Wang, Jiangxi Xiao, Jue Zhang and Yun Yuan
    Citation: BMC Neurology 2021 21:13
  20. SPG11 mutation-related autosomal recessive hereditary spastic paraplegia with thin corpus callosum (HSP-TCC) is the most common cause in complicated forms of HSP, usually presenting comprehensive mental retardati...

    Authors: Chuan Li, Qi Yan, Feng-ju Duan, Chao Zhao, Zhuo Zhang, Ying Du and Wei Zhang
    Citation: BMC Neurology 2021 21:12
  21. The status of research and scientific outputs with regards to bacterial central nervous system (CNS) infection in southeast Asia (SEA) is unknown. This study aimed to analyze and compare bacterial CNS infectio...

    Authors: Francis Gerwin U. Jalipa, Marie Charmaine C. Sy, Adrian I. Espiritu and Roland Dominic G. Jamora
    Citation: BMC Neurology 2021 21:11
  22. Currently, myelin oligodendrocyte glycoprotein (MOG)-IgG-associated encephalomyelitis (MOG-EM) is regarded as an independent inflammatory demyelinating disease. Magnetic resonance imaging (MRI) abnormalities o...

    Authors: Weibing Shen, Yaner Zhang, Chenguang Zhou and Yaoyao Shen
    Citation: BMC Neurology 2021 21:10
  23. Antiphospholipid syndrome (APS) is associated with a high incidence of thrombotic events, either arterial thrombosis or venous thrombosis. However, APS-related non-thrombotic venous stenosis is rarely reported.

    Authors: Si-ying Song, Gary Rajah, Yu-chuan Ding, Xun-ming Ji and Ran Meng
    Citation: BMC Neurology 2021 21:9
  24. Some epidemiologic studies have reported a sharp increase in multiple sclerosis (MS) incidence in different provinces in Iran. This report aimed to investigate more closely the increasing trend of MS incidence...

    Authors: Ali Hosseinzadeh, Behnaz Sedighi, Jamshid Kermanchi, Mohammad Heidari and Ali Akbar Haghdoost
    Citation: BMC Neurology 2021 21:7
  25. Unplanned readmission is one of many measures of the quality of care of pediatric patients with neurological conditions. In this multicenter study, we searched for novel risk factors of readmission of patients...

    Authors: Ryan O’Connell, William Feaster, Vera Wang, Sharief Taraman and Louis Ehwerhemuepha
    Citation: BMC Neurology 2021 21:5
  26. Stroke in adults aged between 18 and 64 years old is increasing significantly worldwide. Studies have reported that this group of young stroke survivors encounters enormous difficulties reintegrating into thei...

    Authors: Suzanne Hoi Shan Lo, Janita Pak Chun Chau, Kai Chow Choi, Edward Wai Ching Shum, Jonas Hon Ming Yeung and Siu Hung Li
    Citation: BMC Neurology 2021 21:3
  27. Migraine is a prevalent and disabling headache disorder that affects more than 1.04 billion individuals world-wide. It can result in reduction in quality of life, increased disability, and high socio-economic ...

    Authors: Philippe Ryvlin, Kirill Skorobogatykh, Andrea Negro, Rainel Sanchez-De La Rosa, Heike Israel-Willner, Christina Sundal, E. Anne MacGregor and Angel L. Guerrero
    Citation: BMC Neurology 2021 21:1
  28. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Xianyue Liu, Ke Han, Mingyi Hu, Huanquan Liao and Qinghua Hou
    Citation: BMC Neurology 2020 20:449

    The original article was published in BMC Neurology 2020 20:423

  29. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12883-020-02027-1.

    Authors: Dan Lu, Yuan Wang, Tianzhi Zhao, Bolin Liu, Lin Ye, Lanfu Zhao, Binfang Zhao, Mingjuan Li, Lin Ma, Zhengmin Li, Jiangtao Niu, Wenhai Lv, Yufu Zhang, Tao Zheng, Yafei Xue, Lei Chen…
    Citation: BMC Neurology 2020 20:448

    The original article was published in BMC Neurology 2020 20:150

  30. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12883-020-02025-3

    Authors: Christessa Emille Que Albay, Frederick Gavril D. Leyson and Federick C. Cheng
    Citation: BMC Neurology 2020 20:447

    The original article was published in BMC Neurology 2020 20:224

  31. Personalized ENCALS survival prediction model reliably estimates the personalized prognosis of patients with amyotrophic lateral sclerosis. Concerns were raised on discussing personalized prognosis without causin...

    Authors: Remko M. van Eenennaam, Willeke J. Kruithof, Michael A. van Es, Esther T. Kruitwagen-van Reenen, Henk-Jan Westeneng, Johanna M. A. Visser-Meily, Leonard H. van den Berg and Anita Beelen
    Citation: BMC Neurology 2020 20:446
  32. Cervicocerebral artery dissection is an important cause of ischemic stroke in young and middle-aged individuals. However, very few studies have compared the differential features between internal carotid arter...

    Authors: Yongjun Wu, Hongbin Chen, Shihui Xing, Shuangquan Tan, Xinran Chen, Yan Tan, Jinsheng Zeng and Jian Zhang
    Citation: BMC Neurology 2020 20:445
  33. Glial fibrillary acidic protein (GFAP) autoimmune astrocytopathy is characterized by GFAP autoantibody positive encephalitis, meningoencephalitis or meningoencephalomyelitis. The initial clinical presentation ...

    Authors: Han Wang, Jerome H. Chin, Bo-yan Fang, Xi Chen, Ai-lin Zhao, Hai-tao Ren and Hong-zhi Guan
    Citation: BMC Neurology 2020 20:443
  34. Although a central role of the thalamus for sleep regulation is undisputed, the exact localization of the crucial structures within the thalamus remains controversial.

    Authors: Peter Nørregaard Hansen, Thomas Krøigård, Nina Nguyen, Rune Vestergaard Frandsen, Poul Jørgen Jennum and Christoph P. Beier
    Citation: BMC Neurology 2020 20:442
  35. Reducing prehospital delay plays an important role in increasing the thrombolysis rate in patients with stroke. Several studies have identified predictors for presentation ≤4.5 h, but few compared these predic...

    Authors: Matthias N. Ungerer, Loraine Busetto, Nima H. Begli, Katharina Riehle, Jens Regula and Christoph Gumbinger
    Citation: BMC Neurology 2020 20:441
  36. Neuroinflammation plays an important role in the pathogenesis of acute ischemic stroke (AIS) and peripheral leukocyte counts have proved to be independent predictors of stroke severity and outcomes. Clinical s...

    Authors: Gabor Tarkanyi, Zsofia Nozomi Karadi, Zsofia Szabo, Istvan Szegedi, Laszlo Csiba and Laszlo Szapary
    Citation: BMC Neurology 2020 20:440
  37. Nine oral disease-modifying therapies (DMTs) have been approved for the treatment of multiple sclerosis (MS) in the United States. Few studies have examined self-reported quality of life (QoL) and functional s...

    Authors: Tamela Stuchiner, Lindsay Lucas, Elizabeth Baraban, Kateri J. Spinelli, Chiayi Chen, Alden Smith, Lobat Hashemi and Stanley Cohan
    Citation: BMC Neurology 2020 20:439
  38. Status epilepticus (SE) is a common neurological emergency condition that especially affects the elderly and old population. Older people with SE frequently have non-convulsive SE (NCSE) and are also at specia...

    Authors: Annekatrin Müller, Anett Schmiedeknecht, Meinhard Mende, Carolin Awissus, Felix Rosenow, Hajo Hamer and Joseph Classen
    Citation: BMC Neurology 2020 20:438
  39. A recent nurse-led proactive care management intervention, Care Coordination for Health Promotion and Activities in Parkinson Disease (CHAPS), improved care quality when compared to usual care in a randomized ...

    Authors: Karen I. Connor, Hilary C. Siebens, Brian S. Mittman, Donna K. McNeese-Smith, David A. Ganz, Frances Barry, Lisa K. Edwards, Michael G. McGowan, Eric M. Cheng and Barbara G. Vickrey
    Citation: BMC Neurology 2020 20:437
  40. A large-bore aspiration catheter can be employed for recanalization of acute basilar artery occlusion. Here we compare the results of mechanical thrombectomy using a stent retriever (SR) and manual aspiration ...

    Authors: Jin Wook Choi, Miran Han, Jung Hyun Park and Woo Sang Jung
    Citation: BMC Neurology 2020 20:434

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