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  1. Language comprehension requires decoding of complex, rapidly changing speech streams. Detecting changes of frequency modulation (FM) within speech is hypothesized as essential for accurate phoneme detection, a...

    Authors: Frank H Duffy, Yaman Z Eksioglu, Alexander Rotenberg, Joseph R Madsen, Aditi Shankardass and Heidelise Als
    Citation: BMC Neurology 2013 13:12
    Content type: Technical advance Published on:

  2. Patients with recent stroke or TIA are at high risk for new vascular events. Several evidence based strategies in secondary prevention of stroke are available but frequently underused. Support programs with mu...

    Authors: Stefanie Leistner, Georg Michelson, Inga Laumeier, Michael Ahmadi, Maureen Smyth, Gabriele Nieweler, Wolfram Doehner, Jan Sobesky, Jochen B Fiebach, Peter Marx, Otto Busse, Friedrich Köhler, Holger Poppert, Martin LJ Wimmer, Thomas Knoll, Paul Von Weitzel-Mudersbach…
    Citation: BMC Neurology 2013 13:11
    Content type: Study protocol Published on:

  3. To improve quality of life (QOL) in patients with multiple sclerosis (MS), it is important to decrease disability and prevent relapse. The aim of this study was to examine the causal and mutual relationships c...

    Authors: Hiromi Kikuchi, Nobuhiro Mifune, Masaaki Niino, Jun-ichi Kira, Tatsuo Kohriyama, Kohei Ota, Masami Tanaka, Hirofumi Ochi, Shunya Nakane and Seiji Kikuchi
    Citation: BMC Neurology 2013 13:10
    Content type: Research article Published on:

  4. Jugular venous reflux (JVR) has been reported to cause cough syncope via retrograde-transmitted venous hypertension and consequently decreased cerebral blood flow (CBF). Unmatched frequencies of JVR and cough ...

    Authors: Chih-Ping Chung, Chun-Yu Cheng, Robert Zivadinov, Wei-Chih Chen, Wen-Yung Sheng, Yu-Chin Lee, Han-Hwa Hu, Hung-Yi Hsu and Kuang-Yao Yang
    Citation: BMC Neurology 2013 13:9
    Content type: Research article Published on:

  5. POLG1 mutations have been associated with MELAS-like phenotypes. However given several clinical differences it is unknown whether POLG1 mutations are possible causes of MELAS or give raise to a distinct clinical...

    Authors: Antonella Cheldi, Dario Ronchi, Andreina Bordoni, Bianca Bordo, Silvia Lanfranconi, Maria Grazia Bellotti, Stefania Corti, Valeria Lucchini, Monica Sciacco, Maurizio Moggio, Pierluigi Baron, Giacomo Pietro Comi, Antonio Colombo and Anna Bersano
    Citation: BMC Neurology 2013 13:8
    Content type: Case report Published on:

  6. Evidence about whether white blood cell (WBC) or its subtypes can act as a biomarker to predict the ischemic stroke events in the general population is scanty, particularly in Asian populations. The aim of thi...

    Authors: Tzy-Haw Wu, Kuo-Liong Chien, Hung-Ju Lin, Hsiu-Ching Hsu, Ta-Chen Su, Ming-Fong Chen and Yuan-Teh Lee
    Citation: BMC Neurology 2013 13:7
    Content type: Research article Published on:

  8. Residual disability after stroke is substantial; 65% of patients at 6 months are unable to incorporate the impaired upper extremity into daily activities. Task-oriented training programs are rapidly being adop...

    Authors: Carolee J Winstein, Steven L Wolf, Alexander W Dromerick, Christianne J Lane, Monica A Nelsen, Rebecca Lewthwaite, Sarah Blanton, Charro Scott, Aimee Reiss, Steven Yong Cen, Rahsaan Holley and Stanley P Azen
    Citation: BMC Neurology 2013 13:5
    Content type: Study protocol Published on:

  9. Responsiveness refers to a measurement tool’s ability to detect change in performance over time. The aim of the review was to summarise studies of responsiveness of lower limb physical performance measures dur...

    Authors: Katharine Scrivener, Catherine Sherrington and Karl Schurr
    Citation: BMC Neurology 2013 13:4
    Content type: Research article Published on:

  10. A strong inverse relationship of functional limitation and socioeconomic status has been established in western ageing society. Functional limitation can be related to chronic diseases, disuse, cognitive decli...

    Authors: Vorapun Senanarong, Kamolthip Harnphadungkit, Niphon Poungvarin, Sathit Vannasaeng, Samut Chongwisal, Tipa Chakorn, Piyanuch Jamjumrus, Atthapon Raksthaput, Sinisa Chaichanettee, Nattapol Aoonkaew, Suthipol Udompunthurak, Rachelle S Doody and Jeffrey L Cummings
    Citation: BMC Neurology 2013 13:3
    Content type: Research article Published on:

  11. It has been suggested that cerebrospinal fluid (CSF) CXCL13 is a diagnostic marker of Lyme neuroborreliosis (LNB), as its levels have been shown to be significantly higher in LNB than in several other CNS infe...

    Authors: Daniel Bremell, Niklas Mattsson, Mikael Edsbagge, Kaj Blennow, Ulf Andreasson, Carsten Wikkelsö, Henrik Zetterberg and Lars Hagberg
    Citation: BMC Neurology 2013 13:2
    Content type: Research article Published on:

  12. Fibrates has been extensively used to improve plasma lipid levels and prevent adverse cardiovascular outcomes. However, the effect of fibrates on stroke is unclear at the present time. We therefore carried out...

    Authors: Yu-Hao Zhou, Xiao-Fei Ye, Fei-Fei Yu, Xiao Zhang, Ying-Yi Qin, Jian Lu and Jia He
    Citation: BMC Neurology 2013 13:1
    Content type: Research article Published on:

  13. Few studies have systematically addressed the role of epidural analgesia and caesarean delivery in predicting the post-partum disease activity in women with Multiple Sclerosis (MS).

    Authors: Luisa Pastò, Emilio Portaccio, Angelo Ghezzi, Bahia Hakiki, Marta Giannini, Lorenzo Razzolini, Elisa Piscolla, Laura De Giglio, Carlo Pozzilli, Damiano Paolicelli, Maria Trojano, Maria Giovanna Marrosu, Francesco Patti, Loredana La Mantia, Gian Luigi Mancardi, Claudio Solaro…
    Citation: BMC Neurology 2012 12:165
    Content type: Research article Published on:

  14. Stroke is one of the major causes of loss of independence, decreased quality of life and mortality among elderly people. About half of the elderly stroke patients discharged after rehabilitation in a nursing h...

    Authors: Tom PMM Vluggen, Jolanda CM van Haastregt, Jeanine A Verbunt, Elly JM Keijsers and Jos MGA Schols
    Citation: BMC Neurology 2012 12:164
    Content type: Study protocol Published on:

  15. Based upon the acquainted loss of dopaminergic neurons in the substantia nigra in Parkinson’s disease (PD), we hypothesised changes in magnetic resonance imaging signal intensities of the basal ganglia to be u...

    Authors: Sarah Jesse, Jan Kassubek, Hans-Peter Müller, Albert C Ludolph and Alexander Unrath
    Citation: BMC Neurology 2012 12:163
    Content type: Research article Published on:

  16. Reduced upper extremity function is one of the most common impairments after stroke and has previously been reported in approximately 70-80% of patients in the acute stage. Acute care for stroke has changes ov...

    Authors: Hanna C Persson, Marina Parziali, Anna Danielsson and Katharina S Sunnerhagen
    Citation: BMC Neurology 2012 12:162
    Content type: Research article Published on:

  17. Physical disability in multiple sclerosis (MS) is frequently characterized by impaired ambulation. Although walking tests have been successfully employed to assess walking ability in MS patients, data analytic...

    Authors: Janina M Burschka, Philipp M Keune, Uwe Menge, Ulrich Hofstadt-van Oy, Patrick Oschmann and Olaf Hoos
    Citation: BMC Neurology 2012 12:161
    Content type: Research article Published on:

  18. This paper provides a strategy to obtain a reliable estimate of the incidence rate for Amyotrophic lateral sclerosis based on data from the National Registry of Rare Diseases (NRRD). In fact, unobserved cases ...

    Authors: Irene Rocchetti, Domenica Taruscio and Daniela Pierannunzio
    Citation: BMC Neurology 2012 12:160
    Content type: Research article Published on:

  19. Nerve damage in leprosy often causes disabilities and deformities. Prednisolone is used to treat nerve function impairment (NFI). However, optimal dose and duration of prednisolone treatment has not been estab...

    Authors: Inge Wagenaar, Wim Brandsma, Erik Post, Wim van Brakel, Diana Lockwood, Peter Nicholls, Paul Saunderson, Cairns Smith, Einar Wilder-Smith and Jan Hendrik Richardus
    Citation: BMC Neurology 2012 12:159
    Content type: Study protocol Published on:

  20. Recombinant factor VIIa (rFVIIa) may be used for rapid hemostasis in life-threatening hemorrhage. In warfarin-associated intracerebral hemorrhage (wICH), FVIIa use is controversial and may carry significant th...

    Authors: Chou Sherry H-Y, Cai Xuemei, Konigsberg Rachael G, Bresette Linda M, Henderson Galen V, Sorond Farzaneh A and Feske Steven K
    Citation: BMC Neurology 2012 12:158
    Content type: Research article Published on:

  21. Many Polio survivors have reduced mobility, pain and fatigue, which make access to conventional forms of aerobic exercise difficult. Inactivity leads to increased risk of health problems, many of which are pre...

    Authors: Deirdre Murray, Dara Meldrum, Roisin Moloney, Anna Campion, Frances Horgan and Orla Hardiman
    Citation: BMC Neurology 2012 12:157
    Content type: Study protocol Published on:

  22. Behavioral changes in patients with amyotrophic lateral sclerosis (ALS) mirror those found in frontotemporal dementia (FTD). Considering the high rate of neuropsychiatric symptoms found in ALS patients, this p...

    Authors: Patricia Lillo, Eneida Mioshi and John R Hodges
    Citation: BMC Neurology 2012 12:156
    Content type: Research article Published on:

  23. To explore current status and choices regarding diagnosis and treatment of Parkinson’s disease (PD) among physicians, general neurologists and movement disorders specialists in China via a national survey.

    Authors: Wei Chen, Shuai Chen, Qin Xiao, Gang Wang and Sheng-Di Chen
    Citation: BMC Neurology 2012 12:155
    Content type: Research article Published on:

  24. In patients with relapsing–remitting multiple sclerosis (RRMS), subcutaneous (sc) interferon (IFN)β-1a and IFNβ-1b have been shown to reduce relapse rates. A formulation of IFNβ-1a has been produced without fe...

    Authors: Barry Singer, Daniel Bandari, Mark Cascione, Christopher LaGanke, John Huddlestone, Randy Bennett and Fernando Dangond
    Citation: BMC Neurology 2012 12:154
    Content type: Research article Published on:

  25. Establishing a confident clinical diagnosis before an advanced stage of illness can be difficult in Creutzfeldt-Jakob disease (CJD) but unlike common causes of dementia, prion diseases can often be diagnosed b...

    Authors: Christopher Carswell, Andrew Thompson, Ana Lukic, John Stevens, Peter Rudge, Simon Mead, John Collinge and Harpreet Hyare
    Citation: BMC Neurology 2012 12:153
    Content type: Research article Published on:

  26. Posterior reversible encephalopathy syndrome (PRES) has been increasingly identified in patients with systemic lupus erythematosus (SLE) owing to the advance in neuroimaging techniques. Prompt diagnosis is piv...

    Authors: Bin Liu, Xuan Zhang, Feng-chun Zhang, Yuan Yao, Ri-zhi Zhou, Miao-Miao Xin and Li-Qin Wang
    Citation: BMC Neurology 2012 12:152
    Content type: Research article Published on:

  27. Little is known about the long-term success of non-drug therapies for treating dementia, especially whether the effects are sustained after therapy ends. Here, we examined the effects of a one-year multimodal ...

    Authors: Katharina Luttenberger, Benjamin Hofner and Elmar Graessel
    Citation: BMC Neurology 2012 12:151
    Content type: Research article Published on:

  28. As low and middle-income countries such as Vietnam experience the health transition from infectious to chronic diseases, the morbidity and mortality from stroke will rise. In line with the recommendation of th...

    Authors: David L Tirschwell, Thanh G N Ton, Kiet A Ly, Quang Van Ngo, Tung T Vo, Chien Hung Pham, William T Longstreth Jr and Annette L Fitzpatrick
    Citation: BMC Neurology 2012 12:150
    Content type: Research article Published on:

  29. The purpose of this study was to examine associations between cardiovascular risk factors and cognitive ability in middle aged and elderly Lithuanian urban population.

    Authors: Abdonas Tamosiunas, Migle Baceviciene, Regina Reklaitiene, Ricardas Radisauskas, Kristina Jureniene, Adelina Azaraviciene, Dalia Luksiene, Vilija Malinauskiene, Evelina Daugeliene and Laura Sapranaviciute-Zabazlajeva
    Citation: BMC Neurology 2012 12:149
    Content type: Research article Published on:

  30. Autism spectrum disorders (ASD) are associated with widespread alterations in white matter (WM) integrity. However, while a growing body of studies is shedding light on microstructural WM alterations in high-f...

    Authors: Lucia Billeci, Sara Calderoni, Michela Tosetti, Marco Catani and Filippo Muratori
    Citation: BMC Neurology 2012 12:148
    Content type: Research article Published on:

  31. The burden of cognitive impairment among school children from developing communities is under reported due to lack of culturally appropriate screening tools. The objective of this study was to validate a cultu...

    Authors: Gwendoline Q Kandawasvika, Paul M Mapingure, Margaret Nhembe, Richard Mtereredzi and Babill Stray-Pedersen
    Citation: BMC Neurology 2012 12:147
    Content type: Research article Published on:

  33. To investigate to what extent Alzheimer's Disease (AD) affects Resting State activity, the possible impairment of independent electrophysiological parameters was determined in Eye-open and Eye-closed Condition...

    Authors: Antonio Tartaglione, Luciano Spadavecchia, Marco Maculotti and Fabio Bandini
    Citation: BMC Neurology 2012 12:145
    Content type: Research article Published on:

  34. We report a female patient with familial Creutzfeldt-Jakob disease with V180I mutation (fCJD with V180I), who was serially followed up with magnetic resonance imaging (MRI) and electroencephalogram (EEG) for u...

    Authors: Kentaro Deguchi, Motonori Takamiya, Shoko Deguchi, Nobutoshi Morimoto, Tomoko Kurata, Yoshio Ikeda and Koji Abe
    Citation: BMC Neurology 2012 12:144
    Content type: Case report Published on:

  35. Reduction of retinal nerve fibre layer (RNFL) thickness was shown as part of the neurodegenerative process in a range of different neurodegenerative pathologies including Alzheimer′s disease (AD), idiopathic P...

    Authors: Sarah Wiethoff, Ahmad Zhour, Ludger Schöls and Manuel Dominik Fischer
    Citation: BMC Neurology 2012 12:143
    Content type: Research article Published on:

  37. Stroke represents one of the most costly and long-term disabling conditions in adulthood worldwide and there is a need to determine the effectiveness of rehabilitation programs in the late phase after stroke. ...

    Authors: Lina Bunketorp Käll, Åsa Lundgren-Nilsson, Christian Blomstrand, Marcela Pekna, Milos Pekny and Michael Nilsson
    Citation: BMC Neurology 2012 12:141
    Content type: Study protocol Published on:

  38. The autophagic vacuolar myopathies (AVM) are a group of inherited myopathies defined by the presence of autophagic vacuoles in pathological muscle specimens. AVM can be categorized into three groups: acid malt...

    Authors: Kota Bokuda, Keizo Sugaya, Shunichiro Tamura, Kazuhito Miyamoto, Shiro Matsubara and Takashi Komori
    Citation: BMC Neurology 2012 12:140
    Content type: Case report Published on:

  39. Acute symptomatic hypoglycaemia is a differential diagnosis in patients presenting with stroke-like neurological impairment, but few textbooks describe the full brain imaging appearances. We systematically rev...

    Authors: Ai Wain Yong, Zoe Morris, Kirsten Shuler, Colin Smith and Joanna Wardlaw
    Citation: BMC Neurology 2012 12:139
    Content type: Research article Published on:

  40. It remains unclear how executive function (EF) is affected in the stage of amnestic mild cognitive impairment (aMCI). Previous studies using different methods to assess EF in patients with aMCI have reached in...

    Authors: Dongming Zheng, Xiaoyu Dong, Hongzan Sun, Yongchuan Xu, Ying Ma and Xiaoming Wang
    Citation: BMC Neurology 2012 12:138
    Content type: Research article Published on:

  41. The aim of this study was to estimate the one-year societal costs due to a stroke event in Italy and to investigate variables associated with costs in different phases following hospital admission.

    Authors: Giovanni Fattore, Aleksandra Torbica, Alessandra Susi, Aguzzi Giovanni, Giancarlo Benelli, Marianna Gozzo and Vito Toso
    Citation: BMC Neurology 2012 12:137
    Content type: Research article Published on:

  42. The Hopkins Verbal Learning Test (HVLT) has been validated for detecting dementia in English-speaking populations. However, no studies have examined the Chinese version of the HVLT scale, and appropriate cut-o...

    Authors: Jing Shi, Jinzhou Tian, Mingqing Wei, Yingchun Miao and Yongyan Wang
    Citation: BMC Neurology 2012 12:136
    Content type: Research article Published on:

  45. Ischemic stroke by septic embolism occurs primarily in the context of infective endocarditis or in patients with a right-to-left shunt and formation of a secondary cerebral abscess is a rare event. Erosion of ...

    Authors: Philipp Albrecht, Mark Stettner, Leila Husseini, Stephan Macht, Sebastian Jander, Colin Mackenzie, Ulrike Oesterlee, Philipp Slotty, Axel Methner, Hans-Peter Hartung and Orhan Aktas
    Citation: BMC Neurology 2012 12:133
    Content type: Case report Published on:

  46. We tested the hypothesis that in patients with occlusion of the terminal internal carotid artery and/or the proximal middle cerebral artery, a diffusion abnormality of 70 ml or less is accompanied by a diffusi...

    Authors: Reza Hakimelahi, Albert J Yoo, Julian He, Lee H Schwamm, Michael H Lev, Pamela W Schaefer and Ramon Gilberto González
    Citation: BMC Neurology 2012 12:132
    Content type: Research article Published on:

  47. Multiple system atrophy (MSA) is a progressive neurodegenerative disorder of unknown etiology, manifesting as combination of parkinsonism, cerebellar syndrome and dysautonomia. Disease-modifying therapies are ...

    Authors: Peter Novak, Arlene Williams, Paula Ravin, Omar Zurkiya, Amir Abduljalil and Vera Novak
    Citation: BMC Neurology 2012 12:131
    Content type: Research article Published on:

  48. The recent SLEEMSA study that evaluated excessive daytime sleepiness (EDS) in Caucasian patients with multiple system atrophy (MSA) demonstrated that EDS was more frequent in patients (28%) than in healthy sub...

    Authors: Takayoshi Shimohata, Hideaki Nakayama, Masahiko Tomita, Tetsutaro Ozawa and Masatoyo Nishizawa
    Citation: BMC Neurology 2012 12:130
    Content type: Research article Published on:

  49. Community ambulation is a highly complex skill requiring the ability to adapt to increased environmental complexity and perform multiple tasks simultaneously. After stroke, individuals demonstrate a diminished...

    Authors: Prudence Plummer-D’Amato, Anastasia Kyvelidou, Dagmar Sternad, Bijan Najafi, Raymond M Villalobos and David Zurakowski
    Citation: BMC Neurology 2012 12:129
    Content type: Study protocol Published on:

  50. To examine the effects of a multicomponent exercise program on the cognitive function of older adults with amnestic mild cognitive impairment (aMCI).

    Authors: Takao Suzuki, Hiroyuki Shimada, Hyuma Makizako, Takehiko Doi, Daisuke Yoshida, Kota Tsutsumimoto, Yuya Anan, Kazuki Uemura, Sangyoon Lee and Hyuntae Park
    Citation: BMC Neurology 2012 12:128
    Content type: Research article Published on:
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BMC Neurology

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