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  1. Content type: Research article

    Living with a chronic condition such as epilepsy can have a debilitating effect on the individual and their carers. Managing epilepsy among people with learning disabilities may present a challenge because of ...

    Authors: Jerry Paul K. Ninnoni

    Citation: BMC Neurology 2019 19:12

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  2. Content type: Research article

    Futile reperfusion (poor functional status despite successful reperfusion) was observed in up to 67% of patients enrolled in recent endovascular treatment (EVT) clinical trials. We investigated the impact of b...

    Authors: Sang-Hwa Lee, Beom Joon Kim, Moon-Ku Han, Tai Hwan Park, Kyung Bok Lee, Byung-Chul Lee, Kyung-Ho Yu, Mi Sun Oh, Jae Kwan Cha, Dae-Hyun Kim, Hyun-Wook Nah, Jun Lee, Soo Joo Lee, Jae Guk Kim, Jong-Moo Park, Kyusik Kang…

    Citation: BMC Neurology 2019 19:11

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  3. Content type: Research article

    A few reliable national data concerning the etiology of non-traumatic spinal cord injury (SCI) in sub-Sahara Africa exists, mainly because of the limitations of diagnostic imaging. These are both expensive and...

    Authors: Abdu K. Musubire, David B. Meya, Elly T. Katabira, Ana Claire L. Meyer, Paul R. Bohjanen, David R. Boulware and Frank Minja

    Citation: BMC Neurology 2019 19:10

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  4. Content type: Case report

    Spinocerebellar ataxia type 31 (SCA 31) is a slowly progressive neurodegenerative disorder characterized by pure cerebellar ataxia. Unlike other CAG repeat diseases, sleep-related problems have not been report...

    Authors: Kazumasa Shindo, Tohko Sato, Hiroaki Murata, Yuta Ichinose, Takanori Hata and Yoshihisa Takiyama

    Citation: BMC Neurology 2019 19:9

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  5. Content type: Research article

    Single acute infarction (SAI) usually had lower risk of stroke recurrence than multiple acute infarctions (MAIs) in minor stroke. To evaluate whether all SAI had lower risk of stroke recurrence than MAIs in mi...

    Authors: Guangyao Wang, Jing Jing, Yuesong Pan, Xia Meng, Xingquan Zhao, Liping Liu, Hao Li, David Wang, Yongjun Wang and Yilong Wang

    Citation: BMC Neurology 2019 19:7

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  6. Content type: Research article

    Frequent somatic mutations of BRAF and CTNNB1 were identified in both histological subtypes of craniopharyngioma (adamantinomatous and papillary) which shed light on target therapy to cure this oncogenic disea...

    Authors: Xi Chen, Yusheng Tong, Zhifeng Shi, Hong Chen, Zhong Yang, Yuanyuan Wang, Liang Chen and Jinhua Yu

    Citation: BMC Neurology 2019 19:6

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  7. Content type: Research article

    Delayed-release dimethyl fumarate (DMF) has demonstrated efficacy and a favorable benefit-risk profile in phase 2 and 3 studies that enrolled predominantly white patients with relapsing-remitting multiple scle...

    Authors: Takahiko Saida, Takashi Yamamura, Takayuki Kondo, Jang Yun, Minhua Yang, Jie Li, Lalitha Mahadavan, Bing Zhu and Sarah I. Sheikh

    Citation: BMC Neurology 2019 19:5

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  8. Content type: Research article

    Stiff Person Syndrome (SPS) is an under-diagnosed disorder that affects mobility and the quality of life of affected patients. The aim of the study is to describe the natural history of SPS, the extent of accu...

    Authors: Goran Rakocevic, Harry Alexopoulos and Marinos C. Dalakas

    Citation: BMC Neurology 2019 19:1

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  9. Content type: Research article

    Transient ischemic attack (TIA) is a risk factor of stroke. Modern treatment regimens and changing risk factors in the population justify new estimates of stroke risk after TIA, and evaluation of the recommend...

    Authors: Fredrik Ildstad, Hanne Ellekjær, Torgeir Wethal, Stian Lydersen, Janne Kutschera Sund, Hild Fjærtoft, Stephan Schüler, Jens Wilhelm Horn, Geir Bråthen, Ann-Grete Midtsæther, Åse Hagen Morsund, Marja-Liisa Lillebø, Yngve Müller Seljeseth and Bent Indredavik

    Citation: BMC Neurology 2019 19:2

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  10. Content type: Research article

    Several neuroimaging studies have reported neurophysiological alterations in patients with benign childhood epilepsy with centrotemporal spikes (BCECTS). However, reported outcomes have been inconsistent, and ...

    Authors: Ye-Hwa Jun, Tae-Hoon Eom, Young-Hoon Kim, Seung-Yun Chung, In-Goo Lee and Jung-Min Kim

    Citation: BMC Neurology 2019 19:3

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  11. Content type: Case report

    Leber’s hereditary optic neuropathy (LHON) is a mitochondrial disease characterized by visual loss consequent to optic nerve atrophy. In some cases, LHON is associated with heterogeneous neurological extraocul...

    Authors: Eleonora Mauri, Robertino Dilena, Antonio Boccazzi, Dario Ronchi, Daniela Piga, Fabio Triulzi, Delia Gagliardi, Roberta Brusa, Irene Faravelli, Nereo Bresolin, Francesca Magri, Stefania Corti and Giacomo P. Comi

    Citation: BMC Neurology 2018 18:220

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  12. Content type: Case report

    Dopamine agonists (DAs) are efficacious for the treatment of motor and nonmotor symptoms in patients with Parkinson’s disease (PD). The treatment of PD with DAs is often complicated by adverse drug reactions (...

    Authors: Piao Zhang, Yan Li, Kun Nie, Lijuan Wang and Yuhu Zhang

    Citation: BMC Neurology 2018 18:221

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  13. Content type: Research article

    Unplanned readmission within 31 days of discharge after stroke is a useful indicator for monitoring quality of hospital care. We evaluated the risk factors associated with 31-day unplanned readmission of strok...

    Authors: Tiancai Wen, Baoyan Liu, Xia Wan, Xiaoping Zhang, Jin Zhang, Xuezhong Zhou, Alexander Y. L. Lau and Yanning Zhang

    Citation: BMC Neurology 2018 18:218

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  14. Content type: Case report

    Multiple acyl-CoA dehydrogenase deficiency (MADD) showed great clinical heterogeneity and poses a challenge to diagnosis. Guillain-Barré syndrome (GBS) is an acute-onset autoimmune-mediated peripheral neuropat...

    Authors: Daojun Hong, Yanyan Yu, Yuyao Wang, Yan Xu and Jun Zhang

    Citation: BMC Neurology 2018 18:219

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  15. Content type: Research article

    In acute ischemic stroke patients, telestroke technology provides sustainable approaches to improve the use of thrombolysis therapy. How this is achieved as it relates to inclusion or exclusion of clinical ris...

    Authors: Leanne Brecthel, Jordan Gainey, Alexandria Penwell and Thomas I. Nathaniel

    Citation: BMC Neurology 2018 18:215

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  16. Content type: Case report

    Myelin oligodendrocyte glycoprotein immunoglobulin G1 (MOG-IgG1)-associated disease is suggested as a separate disease entity distinct from multiple sclerosis and neuromyelitis optica spectrum disorder. Noneth...

    Authors: Seok-Jin Choi, Boram Kim, Haeng-Jin Lee, Seong-Joon Kim, Sung-Min Kim and Jung-Joon Sung

    Citation: BMC Neurology 2018 18:216

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  17. Content type: Research article

    The Paced Auditory Serial Addition Test (PASAT) is a useful cognitive test in patients with multiple sclerosis (MS), assessing sustained attention and information processing speed. However, the neural underpin...

    Authors: Jordi A. Matias-Guiu, Ana Cortés-Martínez, Paloma Montero, Vanesa Pytel, Teresa Moreno-Ramos, Manuela Jorquera, Miguel Yus, Juan Arrazola and Jorge Matías-Guiu

    Citation: BMC Neurology 2018 18:214

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  18. Content type: Research article

    Assessment on the prognosis of amyotrophic lateral sclerosis (ALS) is becoming a focus of research in recent years since there is no effective treatment. The aim of the research is to explore the major factors...

    Authors: Chun-Jiang Yu, Li Wang, Sen-Lin Mao, Ying Zhang, Ling-Ling Song, Ling-Yu Cai and Ye Tao

    Citation: BMC Neurology 2018 18:211

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  19. Content type: Research article

    The relationship between cognitive assessment results in multiple sclerosis (MS) and performance in daily activities (DAs) remains unclear. Our study aimed to evaluate the relationship between cognitive functi...

    Authors: G. Fenu, M. Fronza, L. Lorefice, M. Arru, G. Coghe, J. Frau, M. G. Marrosu and E. Cocco

    Citation: BMC Neurology 2018 18:212

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  20. Content type: Case report

    Cortical ischemic lesions represent the predominant pathomorphological pattern of focal lesions after aneurysmal subarachnoid hemorrhage (aSAH). Autopsy studies suggest that they occur adjacent to subarachnoid...

    Authors: Christian Schinke, Viktor Horst, Ludwig Schlemm, Matthias Wawra, Michael Scheel, Jed A. Hartings and Jens P. Dreier

    Citation: BMC Neurology 2018 18:210

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  21. Content type: Research article

    Amyotrophic Lateral Sclerosis (ALS) is a rapid progressive neurodegenerative disease, characterized by a selective loss of motor neurons, brain stem and spinal cord which leads to deterioration of motor abilit...

    Authors: Isabela Lopes Trevizan, Talita Dias Silva, Helen Dawes, Thais Massetti, Tânia Brusque Crocetta, Francis Meire Favero, Acary Souza Bulle Oliveira, Luciano Vieira de Araújo, Ana Carolina Costa Santos, Luiz Carlos de Abreu, Shelly Coe and Carlos Bandeira de Mello Monteiro

    Citation: BMC Neurology 2018 18:209

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  22. Content type: Case report

    We reported a case of an adult that presented Guillain-Barré syndrome (GBS) after bacterial meningitis which was secondary to chronic suppurative otitis media (CSOM). To our knowledge, this is the first case i...

    Authors: Li Ding, Zhongjun Chen, Yan Sun, Haiping Bao, Xiao Wu, Lele Zhong, Pei Zhang, Yongzhong Lin and Ying Liu

    Citation: BMC Neurology 2018 18:208

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  23. Content type: Research article

    Two-dimensional high-resolution MRI (2D HRMRI) faces many technical challenges for fully assessing morphologic characteristics of inherent tortuous basilar arteries. Our aim was to investigate remodeling mecha...

    Authors: Runcai Guo, Xuebin Zhang, Xianjin Zhu, Zunjing Liu and Sheng Xie

    Citation: BMC Neurology 2018 18:206

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  24. Content type: Case report

    Intracranial hemorrhage is a rare but potentially severe complication of spinal surgery. Most reported post-operative ICH cases consist of cerebellar hemorrhage. There are fewer reported cases of supratentoria...

    Authors: Brent Berry, Malik Ghannam, Caitlin Bell, Sami Ghazaleh, Sherief Boss, Christopher Streib and Mustapha Ezzeddine

    Citation: BMC Neurology 2018 18:204

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  25. Content type: Research article

    To assess the feasibility of using automated capture of Electronic Medical Record (EMR) data to build predictive models for amyotrophic lateral sclerosis (ALS) outcomes.

    Authors: Alex G. Karanevich, Luke J. Weisbrod, Omar Jawdat, Richard J. Barohn, Byron J. Gajewski, Jianghua He and Jeffrey M. Statland

    Citation: BMC Neurology 2018 18:205

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  26. Content type: Research article

    Neuronal ceroid lipofuscinoses type I and type II (NCL1 and NCL2) also known as Batten disease are the commonly observed neurodegenerative lysosomal storage disorder caused by mutations in the PPT1 and TPP1 genes...

    Authors: Jayesh Sheth, Mehul Mistri, Riddhi Bhavsar, Dhairya Pancholi, Mahesh Kamate, Neerja Gupta, Madhulika Kabra, Sanjiv Mehta, Sheela Nampoothiri, Arpita Thakker, Vivek Jain, Raju Shah and Frenny Sheth

    Citation: BMC Neurology 2018 18:203

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  27. Content type: Research article

    Recurrent seizure risks in HIV-positive people with new-onset seizure are largely unknown, making it challenging to offer optimal recommendations regarding antiepileptic drug (AED) initiation. Existing outcome...

    Authors: Melissa A. Elafros, Brent A. Johnson, Omar K. Siddiqi, Jason F. Okulicz, Izukanji Sikazwe, Christopher M. Bositis, Michael J. Potchen, Igor J. Koralnik, William H. Theodore, Lisa Kalungwana and Gretchen L. Birbeck

    Citation: BMC Neurology 2018 18:201

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  28. Content type: Research article

    Cerebrospinal fluid (CSF) biomarkers reflect ongoing processes in the brain. Growth-associated protein 43 (GAP-43) is highly upregulated in brain tissue shortly after experimental ischemia suggesting the CSF G...

    Authors: Åsa Sandelius, Nicholas C. Cullen, Åsa Källén, Lars Rosengren, Crister Jensen, Vesna Kostanjevecki, Manu Vandijck, Henrik Zetterberg and Kaj Blennow

    Citation: BMC Neurology 2018 18:202

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  29. Content type: Research article

    Elevated plasma homocysteine (Hcy) is an independent risk factor for ischemic stroke. This study aimed to evaluate the association between Hcy levels and intracranial plaque characteristics and to investigate ...

    Authors: Shan shan Lu, Jun Xie, Chun qiu Su, Song Ge, Hai bin Shi and Xun ning Hong

    Citation: BMC Neurology 2018 18:200

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  30. Content type: Research article

    In cases showing cerebrospinal fluid (CSF) redistribution as a compensatory mechanism in acute intracranial hypertension, the optic nerve sheath diameter (ONSD) can be used to estimate intracranial pressure (I...

    Authors: Yuzhi Gao, Qiang Li, Chunshuang Wu, Shaoyun Liu and Mao Zhang

    Citation: BMC Neurology 2018 18:199

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  31. Content type: Research article

    Warfarin therapies not only are used to prevent stroke in patients with high risk of cardioembolism such as patients with atrial fibrillation (AF) and rheumatic heart disease (RHD), but also was associated wit...

    Authors: Jiaying Zhu, Mengmeng Ma, Yijia Guo, Muke Zhou, Jian Guo and Li He

    Citation: BMC Neurology 2018 18:194

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  32. Content type: Case report

    The majority of ruptured intracranial aneurysms are combined with subarachnoid hemorrhage, but patients with only intracerebral hematoma without any subarachnoid hemorrhage are extremely rare.

    Authors: Guangyong Chen, Meiling Xu, Long Ma, Yufei Gao, Chengyan He and Jinnan Zhang

    Citation: BMC Neurology 2018 18:197

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  33. Content type: Research article

    Hereditary sensory and autonomic neuropathy type 2 (HSAN2) is an autosomal recessive disorder with predominant sensory dysfunction and severe complications such as limb destruction. There are different subtype...

    Authors: Behrouz Rahmani, Fatemeh Fekrmandi, Keivan Ahadi, Tannaz Ahadi, Afagh Alavi, Abolhassan Ahmadiani and Sareh Asadi

    Citation: BMC Neurology 2018 18:195

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  34. Content type: Case report

    Autosomal recessive hereditary spastic paraplegias (ARHSPs) are a group of clinically and genetically heterogeneous neurodegenerative diseases with progressive spasticity and weakness in the lower limbs. Mutat...

    Authors: Xiaoqian Zhang, Lei Zhang, Yanqing Wu, Gang Li, Shengcai Chen, Yuanpeng Xia and Hongge Li

    Citation: BMC Neurology 2018 18:196

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  35. Content type: Study protocol

    Early and late onset post-stroke cognitive impairment (PCI) contributes substantially to disability following stroke, and is a high priority within stroke research. The aetiology for PCI is complex and related...

    Authors: Pernille Thingstad, Torunn Askim, Mona K. Beyer, Geir Bråthen, Hanne Ellekjær, Hege Ihle-Hansen, Anne Brita Knapskog, Stian Lydersen, Ragnhild Munthe-Kaas, Halvor Næss, Sarah T. Pendlebury, Yngve Muller Seljeseth and Ingvild Saltvedt

    Citation: BMC Neurology 2018 18:193

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  36. Content type: Research article

    There is limited data on the effects of medication-related adverse events occurring during inpatient stays for stroke. The objectives of our study were to characterize reasons for acute readmission after acute...

    Authors: James A. G. Crispo, Dylan P. Thibault, Yannick Fortin, Daniel Krewski and Allison W. Willis

    Citation: BMC Neurology 2018 18:192

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  37. Content type: Research article

    Fibromyalgia is a chronic disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory, and mood problems. Recently, occipital nerve field stimulation (ONS) has been proposed...

    Authors: Shaheen Ahmed, Mark Plazier, Jan Ost, Gaetane Stassijns, Steven Deleye, Sarah Ceyssens, Patrick Dupont, Sigrid Stroobants, Steven Staelens, Dirk De Ridder and Sven Vanneste

    Citation: BMC Neurology 2018 18:191

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  38. Content type: Case report

    Posterior reversible encephalopathy syndrome (PRES) is described as a clinical-radiological disease entity with good prognosis. In brain MRI, PRES generally presents with vasogenic edema. Although PRES is indu...

    Authors: Yoshitsugu Nakamura, Masakazu Sugino, Akihiro Tsukahara, Hiroko Nakazawa, Naomune Yamamoto and Shigeki Arawaka

    Citation: BMC Neurology 2018 18:190

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  39. Content type: Case report

    Paraneoplastic neurological syndromes (PNS) are rare disorders associated with cancer and are believed to be immune mediated. Patients with autonomic PNS suffer from variable combinations of parasympathetic an...

    Authors: Tatsuya Ueno, Yukihiro Hasegawa, Rie Hagiwara, Tomoya Kon, Jin-ichi Nunomura and Masahiko Tomiyama

    Citation: BMC Neurology 2018 18:189

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  40. Content type: Research article

    Galcanezumab, a humanized monoclonal antibody that selectively binds to the calcitonin gene-related peptide, has demonstrated in previous Phase 2 and Phase 3 clinical studies (≤6-month of treatment) a reductio...

    Authors: Angelo Camporeale, David Kudrow, Ryan Sides, Shufang Wang, Annelies Van Dycke, Katherine J. Selzler and Virginia L. Stauffer

    Citation: BMC Neurology 2018 18:188

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  41. Content type: Study protocol

    Patients with ischaemic stroke or transient ischaemic attack (TIA) are at high risk of future cardiovascular events. Despite compelling evidence about the efficacy of secondary prevention, a substantial gap ex...

    Authors: Thomas Toell, Christian Boehme, Lukas Mayer, Stefan Krebs, Clemens Lang, Karin Willeit, Barbara Prantl, Michael Knoflach, Gerhard Rumpold, Gudrun Schoenherr, Andrea Griesmacher, Peter Willeit, Julia Ferrari, Wilfried Lang, Stefan Kiechl and Johann Willeit

    Citation: BMC Neurology 2018 18:187

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  42. Content type: Research article

    Little is known about whether tolerability and adherence to treatment can be influenced by weather and temperature conditions. The objective of this study was to assess monthly and seasonal adherence to and sa...

    Authors: Spyros N. Deftereos, Evangelos Koutlas, Efrosini Koutsouraki, Athanassios Kyritsis, Panagiotis Papathanassopoulos, Nikolaos Fakas, Vaia Tsimourtou, Nikolaos Vlaikidis, Antonios Tavernarakis, Konstantinos Voumvourakis, Michalis Arvanitis, Dimitrios Sakellariou and Filippo DeLorenzo

    Citation: BMC Neurology 2018 18:186

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