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  1. Content type: Research article

    There are currently no standard diagnostic criteria for characterizing advanced Parkinson’s disease (APD) in clinical practice, a critical component in determining ongoing clinical care and therapeutic strateg...

    Authors: Alfonso Fasano, Victor S. C. Fung, Leonardo Lopiano, Bulent Elibol, Irina G. Smolentseva, Klaus Seppi, Annamária Takáts, Koray Onuk, Juan Carlos Parra, Lars Bergmann, Kavita Sail, Yash Jalundhwala and Zvezdan Pirtosek

    Citation: BMC Neurology 2019 19:50

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  4. Content type: Research article

    The prevalence of Restless legs syndrome (RLS) in End Stage Renal Disease (ESRD) patients is higher than that in the general population. However, the associations of RLS within the ESRD population are inconsis...

    Authors: Xiao-Wei Lin, Jun-Fang Zhang, Meng-Yao Qiu, Ling-Yan Ni, Hong-Lei Yu, Sheng-Han Kuo, William G. Ondo, Qing Yu and Yun-Cheng Wu

    Citation: BMC Neurology 2019 19:47

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  5. Content type: Case report

    Contrast-induced encephalopathy (CIE) is a well-known complication of iodinated contrast agents during angiography and vascular interventions. It can manifest as hemiparesis, cortical blindness, speech changes...

    Authors: Wei Zhao, Jinping Zhang, Yun Song, Lili Sun, Meimei Zheng, Hao Yin, Jun Zhang, Wei Wang and Ju Han

    Citation: BMC Neurology 2019 19:46

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  7. Content type: Research article

    The genetic risk factors for carotid stenosis are not fully understood. The aim of this study is to investigate the relationship between variants in platelet activation-relevant genes and carotid stenosis in p...

    Authors: Xingyang Yi, Jing Lin, Qiang Zhou, Ruyue Huang and Zhenxiao Chai

    Citation: BMC Neurology 2019 19:44

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  8. Content type: Case report

    Dural arteriovenous fistula (DAVF) is an uncommon subtype among the intracranial arteriovenous malformations, which is characterized by pathological anastomoses between meningeal arteries and dural venous sinu...

    Authors: Guichen Li, Yang Zhang, Jinchuan Zhao, Xiaobo Zhu, Jinlu Yu and Kun Hou

    Citation: BMC Neurology 2019 19:43

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  9. Content type: Research article

    We aimed to produce a detailed neuropathological analysis of pyramidal motor system pathology and provide its clinical pathological correlation in cases with definite progressive supranuclear palsy (PSP).

    Authors: Zuzana Stejskalova, Zdenek Rohan, Robert Rusina, Adam Tesar, Jaromir Kukal, Gabor G. Kovacs, Ales Bartos and Radoslav Matej

    Citation: BMC Neurology 2019 19:42

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  11. Content type: Research article

    The efficacy of early supported discharge (ESD) has not been tested in current stroke care setting, which provide relatively short hospital stays, access to hyper-acute therapies and early carotid stenosis int...

    Authors: Anna Bråndal, Marie Eriksson, Eva-Lotta Glader and Per Wester

    Citation: BMC Neurology 2019 19:40

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  12. Content type: Study protocol

    After discharge from hospital following a stroke, prescriptions of community-based rehabilitation are often downgraded to “maintenance” rehabilitation or discontinued. This classic therapeutic behavior stems f...

    Authors: Jean-Michel Gracies, Maud Pradines, Mouna Ghédira, Catherine-Marie Loche, Valentina Mardale, Catherine Hennegrave, Caroline Gault-Colas, Etienne Audureau, Emilie Hutin, Marjolaine Baude and Nicolas Bayle

    Citation: BMC Neurology 2019 19:39

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  14. Content type: Study protocol

    Studies have shown positive effects of therapeutic exercise on motor- and cognitive function as well as on psychosocial outcomes in persons with multiple sclerosis (MS). A reduction of inflammatory stress thro...

    Authors: Niklas Joisten, Annette Rademacher, Wilhelm Bloch, Alexander Schenk, Max Oberste, Ulrik Dalgas, Dawn Langdon, Daniel Caminada, Mette-Triin Purde, Roman Gonzenbach, Jan Kool, Philipp Zimmer and Jens Bansi

    Citation: BMC Neurology 2019 19:37

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  15. Content type: Research article

    Neuromyelitis optica (NMO) is a severe inflammatory autoimmune disorder of the central nervous system and often results in paralysis or blindness. Rituximab (RTX) is a mouse–human chimeric monoclonal antibody ...

    Authors: Fulin Gao, Bingyan Chai, Cheng Gu, Ruipeng Wu, Tong Dong, Yuping Yao and Yi Zhang

    Citation: BMC Neurology 2019 19:36

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  16. Content type: Study protocol

    Nodding syndrome is a poorly understood neurological disorder of unknown aetiology, affecting several thousand children in Africa. There has been a consistent epidemiological association with infection by the ...

    Authors: Richard Idro, Ronald Anguzu, Rodney Ogwang, Pamela Akun, Catherine Abbo, Amos Deogratius Mwaka, Bernard Opar, Phyellister Nakamya, Mark Taylor, Alison Elliott, Angela Vincent, Charles Newton and Kevin Marsh

    Citation: BMC Neurology 2019 19:35

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  17. Content type: Case report

    Moyamoya vasculopathy (MMV) associated with Graves’ disease (GD) is a rare condition resulting in ischemic stroke accompanied by thyrotoxicity. Radiological findings of vasculitis have been reported in the wal...

    Authors: Hiroto Ito, Syunsuke Yokoi, Kinya Yokoyama, Takumi Asai, Kenji Uda, Yoshio Araki, Syuntaro Takasu, Rei Kobayashi, Hisashi Okada and Satoshi Okuda

    Citation: BMC Neurology 2019 19:34

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  18. Content type: Research article

    Although patients with dementia frequently experience neuropsychological symptoms (NPS) such as agitation, which profoundly impacts patients, caregivers, and the healthcare system, few studies have evaluated t...

    Authors: Myrlene Sanon Aigbogun, Robert Stellhorn, Ann Hartry, Ross A. Baker and Howard Fillit

    Citation: BMC Neurology 2019 19:33

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  19. Content type: Case report

    Collagen VI-related myopathies are a spectrum of muscular diseases with features of muscle weakness and atrophy, multiple contractures of joints, distal hyperextensibility, severe respiratory dysfunction and c...

    Authors: Mengxin Bao, Fei Mao, Zhangning Zhao, Gaoting Ma, Guangjun Xu, Wenjuan Xu, Huan Chen and Meijia Zhu

    Citation: BMC Neurology 2019 19:32

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  20. Content type: Research article

    Ischemic stroke is a leading cause of mortality and morbidity worldwide. Stenosis or blockage of an artery from atherosclerosis can cause insufficient cerebral blood supply, which leads to ischemic stroke. It ...

    Authors: Yan Jiang, Xiaomin Liu, Yifeng Du and Shengnian Zhou

    Citation: BMC Neurology 2019 19:31

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  21. Content type: Research article

    Posterior reversible encephalopathy syndrome (PRES) is a complication that occurs during various diseases’ treatment. Imaging examination is the gold standard for diagnosis. PRES frequently occurrence in patie...

    Authors: Li-Ping Zou, Li-Ying Liu, Hui Li, Yang-Yang Wang, Ying Liu, Jing Chen, Lin-Yan Hu, Meng-Jia Liu, Meng-Na Zhang, Qian Lu and Shu-Fang Ma

    Citation: BMC Neurology 2019 19:30

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  22. Content type: Research article

    Individuals with epilepsy who cannot be adequately controlled with anti-epileptic drugs, refractory epilepsy, may be suitable for surgical treatment following detailed assessment. This is a complex process and...

    Authors: Virginia Mumford, Frances Rapport, Patti Shih, Rebecca Mitchell, Andrew Bleasel, Armin Nikpour, Geoffrey Herkes, Amy MacRae, Melissa Bartley, Sanjyot Vagholkar and Jeffrey Braithwaite

    Citation: BMC Neurology 2019 19:29

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  23. Content type: Case report

    Periodic alternating ping-pong gaze (PPG) is a rare disease with few reports. To our knowledge, there was no report on anti GQ1b antibody syndrome accompanied by PPG. This paper reported a case of anti GQ1b an...

    Authors: Jingzhe Han, Yanan Xie, Haiyan Yan, Yuecheng Cao, HongmeiWang and Duanhua Cao

    Citation: BMC Neurology 2019 19:28

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  24. Content type: Research article

    Autism prevalence continues to grow, yet a universally agreed upon etiology is lacking despite manifold evidence of abnormalities especially in terms of genetics and epigenetics. The authors postulate that the...

    Authors: Frank H. Duffy and Heidelise Als

    Citation: BMC Neurology 2019 19:27

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  25. Content type: Case report

    Mixed cerebrovascular disease is a diagnostic entity that presents with hemorrhagic and ischemic stroke clinically and/or subclinically. Here, we report a patient with mixed vascular risk factors, who presente...

    Authors: Dian He, YunLi Yu, Shan Wu, ShuFen Tian, Hui Yu, Shu Xu and Lan Chu

    Citation: BMC Neurology 2019 19:26

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  26. Content type: Research article

    Atrial fibrillation (AF) is present in 15–20% of patients with acute ischemic stroke. Oral anticoagulation reduces the risk of AF-related recurrent stroke but clinical guideline recommendations are rather vagu...

    Authors: Alexander Wutzler, Christos Krogias, Anna Grau, Roland Veltkamp, Peter U. Heuschmann and Karl Georg Haeusler

    Citation: BMC Neurology 2019 19:25

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  27. Content type: Study protocol

    Malnutrition is one of the crucial factors associated with poor prognosis in critical ill patients, yet a significant evidence gap surrounds the management of initial enteral feeding in severe stroke. The Opti...

    Authors: Fang Yuan, Fang Yang, Wei Zhang, Yi Jia, Yaling Ma, Yongcai Qu, Xinglai Wang, Kang Huo, Chengkai Wang, Xiangjun Yuan, Chaohui Song, Bei Zhang and Wen Jiang

    Citation: BMC Neurology 2019 19:24

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  28. Content type: Research article

    Serum hematological indices such as the neutrophil-lymphocyte ratio (NLR) or monocyte-lymphocyte ratio (MLR) have been used as biomarkers of pathogenic inflammation and prognostication in multiple areas of med...

    Authors: Christopher C. Hemond, Bonnie I. Glanz, Rohit Bakshi, Tanuja Chitnis and Brian C. Healy

    Citation: BMC Neurology 2019 19:23

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  29. Content type: Research article

    Endothelial progenitor cells (EPCs) play an important role in ischemic stroke. However, there are few studies on the relationship between EPC and nondisabling ischemic cerebrovascular events. Our aim was to in...

    Authors: Wang Zhao, Libo Zhao, Juan Liao, Yong Luo and Lanying He

    Citation: BMC Neurology 2019 19:22

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  30. Content type: Research article

    Fatigability has emerged as an important dimension of physical impairment in patients with Spinal Muscular Atrophy (SMA). At present reliable and valid outcome measures for both mildly and severely affected pa...

    Authors: Bart Bartels, Laura E. Habets, Marloes Stam, Renske I. Wadman, Camiel A. Wijngaarde, Marja A. G. C. Schoenmakers, Tim Takken, Erik H.J. Hulzebos, W. Ludo van der Pol and Janke F. de Groot

    Citation: BMC Neurology 2019 19:21

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  31. Content type: Study protocol

    Currently there are no disease-modifying treatments for Parkinson’s disease dementia (PDD), a condition linked to aggregation of the protein α-synuclein in subcortical and cortical brain areas. One of the lead...

    Authors: C. R. A. Silveira, J. MacKinley, K. Coleman, Z. Li, E. Finger, R. Bartha, S. A. Morrow, J. Wells, M. Borrie, R. G. Tirona, C. A. Rupar, G. Zou, R. A. Hegele, D. Mahuran, P. MacDonald, M. E. Jenkins…

    Citation: BMC Neurology 2019 19:20

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  32. Content type: Case report

    Anti leucine-rich glioma inactivated 1 (LGI1) encephalitis is a rare autoimmune encephalitis (AE), characterized by acute or subacute cognitive impairment, faciobrachial dystonic seizures, psychiatric disturba...

    Authors: Xuanting Li, Junliang Yuan, Lei Liu and Wenli Hu

    Citation: BMC Neurology 2019 19:19

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  33. Content type: Research article

    Traumatic brain injuries in Uganda are on the increase, however little is known about the neuropsychological outcomes in survivors. This study characterized patients with traumatic brain injury (TBI) and the a...

    Authors: Paul Bangirana, Bruno Giordani, Olive Kobusingye, Letisia Murungyi, Charles Mock, Chandy C. John and Richard Idro

    Citation: BMC Neurology 2019 19:18

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  35. Content type: Correction

    Following publication of the original article [1], the authors reported the following errors on their article.

    Authors: Erin Oerton and Andreas Bender

    Citation: BMC Neurology 2019 19:16

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    The original article was published in BMC Neurology 2017 17:58

  36. Content type: Research article

    The burden of hospital readmission after stroke is substantial, but little knowledge exists on factors associated with long-term readmission after stroke. In a cohort comprising patients with ischemic stroke a...

    Authors: Anna Therese Bjerkreim, Halvor Naess, Andrej Netland Khanevski, Lars Thomassen, Ulrike Waje-Andreassen and Nicola Logallo

    Citation: BMC Neurology 2019 19:15

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  37. Content type: Case report

    The signs and symptoms of acute alcohol intoxication resemble those of vertebrobasilar stroke. Due to their shared symptoms including double vision, nystagmus, dysarthria, and ataxia, the differential diagnosi...

    Authors: Tamas Arokszallasi, Eszter Balogh, Laszlo Csiba, Istvan Fekete, Klara Fekete and Laszlo Olah

    Citation: BMC Neurology 2019 19:14

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  38. Content type: Research article

    Epilepsy is one of the most common chronic disabling neurologic diseases. The purpose of our study was to investigate whether there is an association between t-PA (tissue plasminogen activator, rs2020918 and rs46...

    Authors: Wenxiu Han, Pei Jiang, Yujin Guo, Pengfei Xu, Ruili Dang, Gongying Li, Xin He, Dehua Liao and Genquan Yan

    Citation: BMC Neurology 2019 19:13

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  39. Content type: Research article

    Living with a chronic condition such as epilepsy can have a debilitating effect on the individual and their carers. Managing epilepsy among people with learning disabilities may present a challenge because of ...

    Authors: Jerry Paul K. Ninnoni

    Citation: BMC Neurology 2019 19:12

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  40. Content type: Research article

    Futile reperfusion (poor functional status despite successful reperfusion) was observed in up to 67% of patients enrolled in recent endovascular treatment (EVT) clinical trials. We investigated the impact of b...

    Authors: Sang-Hwa Lee, Beom Joon Kim, Moon-Ku Han, Tai Hwan Park, Kyung Bok Lee, Byung-Chul Lee, Kyung-Ho Yu, Mi Sun Oh, Jae Kwan Cha, Dae-Hyun Kim, Hyun-Wook Nah, Jun Lee, Soo Joo Lee, Jae Guk Kim, Jong-Moo Park, Kyusik Kang…

    Citation: BMC Neurology 2019 19:11

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  41. Content type: Research article

    A few reliable national data concerning the etiology of non-traumatic spinal cord injury (SCI) in sub-Sahara Africa exists, mainly because of the limitations of diagnostic imaging. These are both expensive and...

    Authors: Abdu K. Musubire, David B. Meya, Elly T. Katabira, Ana Claire L. Meyer, Paul R. Bohjanen, David R. Boulware and Frank Minja

    Citation: BMC Neurology 2019 19:10

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  42. Content type: Case report

    Spinocerebellar ataxia type 31 (SCA 31) is a slowly progressive neurodegenerative disorder characterized by pure cerebellar ataxia. Unlike other CAG repeat diseases, sleep-related problems have not been report...

    Authors: Kazumasa Shindo, Tohko Sato, Hiroaki Murata, Yuta Ichinose, Takanori Hata and Yoshihisa Takiyama

    Citation: BMC Neurology 2019 19:9

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  44. Content type: Research article

    Single acute infarction (SAI) usually had lower risk of stroke recurrence than multiple acute infarctions (MAIs) in minor stroke. To evaluate whether all SAI had lower risk of stroke recurrence than MAIs in mi...

    Authors: Guangyao Wang, Jing Jing, Yuesong Pan, Xia Meng, Xingquan Zhao, Liping Liu, Hao Li, David Wang, Yongjun Wang and Yilong Wang

    Citation: BMC Neurology 2019 19:7

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  45. Content type: Research article

    Frequent somatic mutations of BRAF and CTNNB1 were identified in both histological subtypes of craniopharyngioma (adamantinomatous and papillary) which shed light on target therapy to cure this oncogenic disea...

    Authors: Xi Chen, Yusheng Tong, Zhifeng Shi, Hong Chen, Zhong Yang, Yuanyuan Wang, Liang Chen and Jinhua Yu

    Citation: BMC Neurology 2019 19:6

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  46. Content type: Research article

    Delayed-release dimethyl fumarate (DMF) has demonstrated efficacy and a favorable benefit-risk profile in phase 2 and 3 studies that enrolled predominantly white patients with relapsing-remitting multiple scle...

    Authors: Takahiko Saida, Takashi Yamamura, Takayuki Kondo, Jang Yun, Minhua Yang, Jie Li, Lalitha Mahadavan, Bing Zhu and Sarah I. Sheikh

    Citation: BMC Neurology 2019 19:5

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  48. Content type: Research article

    Several neuroimaging studies have reported neurophysiological alterations in patients with benign childhood epilepsy with centrotemporal spikes (BCECTS). However, reported outcomes have been inconsistent, and ...

    Authors: Ye-Hwa Jun, Tae-Hoon Eom, Young-Hoon Kim, Seung-Yun Chung, In-Goo Lee and Jung-Min Kim

    Citation: BMC Neurology 2019 19:3

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  49. Content type: Research article

    Transient ischemic attack (TIA) is a risk factor of stroke. Modern treatment regimens and changing risk factors in the population justify new estimates of stroke risk after TIA, and evaluation of the recommend...

    Authors: Fredrik Ildstad, Hanne Ellekjær, Torgeir Wethal, Stian Lydersen, Janne Kutschera Sund, Hild Fjærtoft, Stephan Schüler, Jens Wilhelm Horn, Geir Bråthen, Ann-Grete Midtsæther, Åse Hagen Morsund, Marja-Liisa Lillebø, Yngve Müller Seljeseth and Bent Indredavik

    Citation: BMC Neurology 2019 19:2

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  50. Content type: Research article

    Stiff Person Syndrome (SPS) is an under-diagnosed disorder that affects mobility and the quality of life of affected patients. The aim of the study is to describe the natural history of SPS, the extent of accu...

    Authors: Goran Rakocevic, Harry Alexopoulos and Marinos C. Dalakas

    Citation: BMC Neurology 2019 19:1

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