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  1. Multiple acyl-CoA dehydrogenase deficiency (MADD) is a riboflavin-responsive lipid-storage myopathy caused by mutations in the EFTA, EFTB or ETFDH genes. We report a Chinese family of Southern Min origin with ...

    Authors: Wei Chen, Youqiao Zhang, Yifeng Ni, Shaoyu Cai, Xin Zheng, Frank L. Mastaglia and Jingshan Wu

    Citation: BMC Neurology 2019 19:330

    Content type: Case report

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  2. To investigate whether the serum free thyroxine (FT4) level is a prognostic factor for the first-attack neuromyelitis optica spectrum disorders (NMOSD).

    Authors: Qianyi He, Lifeng Li, Yanfei Li, Yanhui Lu, Kaimin Wu, Ruiyi Zhang, Junfang Teng, Jie Zhao and Yanjie Jia

    Citation: BMC Neurology 2019 19:329

    Content type: Research article

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  3. Spontaneous conus medullaris infarction is a rare disease. We describe two patients with spontaneous conus medullaris infarction presenting as acute cauda equina syndrome and their unique electromyography (EMG...

    Authors: Yi-Ching Weng, Shy-Chyi Chin, Yah-Yuan Wu and Hung-Chou Kuo

    Citation: BMC Neurology 2019 19:328

    Content type: Case report

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  4. The Editor and Publisher have retracted this article [1]. This article was published as the result of a technical error which resulted in two versions [1, 2] of the same article being published. [2] is the fin...

    Authors: Ginenus Fekadu, Legese Chelkeba and Ayantu Kebede

    Citation: BMC Neurology 2019 19:327

    Content type: Retraction Note

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    The original article was published in BMC Neurology 2019 19:183

  5. Mild Cognitive Impairment (MCI) carries a high risk of progression to Alzheimer’s disease (AD) dementia. Previous clinical trials testing whether cholinesterase inhibitors can slow the rate of progression from...

    Authors: Joy L. Taylor, Benjamin C. Hambro, Nicole D. Strossman, Priyanka Bhatt, Beatriz Hernandez, J. Wesson Ashford, Jauhtai Joseph Cheng, Michael Iv, Maheen M. Adamson, Laura C. Lazzeroni and Margaret Windy McNerney

    Citation: BMC Neurology 2019 19:326

    Content type: Study protocol

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  6. The X-linked form of Charcot-Marie-Tooth disease type 1 (CMTX1) is an inherited peripheral neuropathy that arises in patients with mutations in the gap-junction beta-1 gene (GJB1).

    Authors: Youlong Liang, Jingli Liu, Daobin Cheng, Yu Wu, Liuhong Mo and Wen Huang

    Citation: BMC Neurology 2019 19:325

    Content type: Case report

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  7. In this study, we aimed to understand the trends in total and itemized medical expenses, especially of disease-modifying therapy (DMT), for multiple sclerosis (MS) in Japan through an analysis of health insura...

    Authors: Izumi Kawachi, Shuichi Okamoto, Mariko Sakamoto, Hiroyuki Ohta, Yusuke Nakamura, Kosuke Iwasaki, Manami Yoshida, Shinzo Hiroi and Mieko Ogino

    Citation: BMC Neurology 2019 19:324

    Content type: Research article

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  8. In recent years, the role of neuroinflammation and oxidative stress in migraine pathogenesis has achieved considerable interest; however, to date findings are equivocal. Thus, the objective of this study was t...

    Authors: Mansoureh Togha, Soodeh Razeghi Jahromi, Zeinab Ghorbani, Amir Ghaemi and Pegah Rafiee

    Citation: BMC Neurology 2019 19:323

    Content type: Research article

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  9. Hereditary spastic paraplegia is a large group of degenerative, neurological disorders characterized by progressive lower limb spasticity and weakness. The disease was investigated precisely but still clinicia...

    Authors: Aleksandra Klimkowicz-Mrowiec, Anna Dziubek, Malgorzata Sado, Marek Karpiński and Agnieszka Gorzkowska

    Citation: BMC Neurology 2019 19:322

    Content type: Case report

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  10. Spinal cord infarction (SCI) is rarely caused by vertebral artery dissection (VAD), which is an important cause of posterior circulation stroke in young and middle-aged patients. We report the case of a middle...

    Authors: Yang-Yang Meng, Le Dou, Chun-Mei Wang, De-Zheng Kong, Ying Wei, Li-Shan Wu, Yi Yang and Hong-Wei Zhou

    Citation: BMC Neurology 2019 19:321

    Content type: Case report

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  11. X-linked agammaglobulinaemia (XLA) is a rare inherited primary immunodeficiency disease characterized by the B cell developmental defect, caused by mutations in the gene coding for Bruton’s tyrosine kinase (BT...

    Authors: Ya-Ni Zhang, Yuan-Yuan Gao, Si-Da Yang, Bin-Bin Cao, Ke-Lu Zheng, Ping Wei, Lian-Feng Chen and Wen-Xiong Chen

    Citation: BMC Neurology 2019 19:320

    Content type: Case report

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  12. Authors: Priscila Mara Lorencini Selingardi, Antonia Lilian de Lima Rodrigues, Valquíria Aparecida da Silva, Diego Toledo Reis Mendes Fernandes, Jefferson Rosí Jr, Marco Antônio Marcolin, Lin T. Yeng, André R. Brunoni, Manoel J. Teixeira, Ricardo Galhardoni and Daniel Ciampi de Andrade

    Citation: BMC Neurology 2019 19:319

    Content type: Research article

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  13. Huntington’s disease (HD) is a rare, genetic, neurodegenerative and ultimately fatal disease with no cure or progression-delaying treatment currently available. HD is characterized by a triad of cognitive, beh...

    Authors: Christoph Ohlmeier, Kai-Uwe Saum, Wolfgang Galetzka, Dominik Beier and Holger Gothe

    Citation: BMC Neurology 2019 19:318

    Content type: Research article

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  14. Cerebral palsy (CP) is considered as the main cause of severe physical impairment and malnutrition in children. This cross-sectional study intended to survey the nutritional status of children cerebral palsy i...

    Authors: Abdul Rahman Almuneef, Ali Almajwal, Iftikhar Alam, Mahmoud Abulmeaty, Bader Al Bader, Mohamed Farouq Badr, May Almuammar and Suhail Razak

    Citation: BMC Neurology 2019 19:317

    Content type: Research article

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  15. Huntington’s disease (HD) is a progressive, neurological disorder that results in both cognitive and physical impairments. These impairments affect an individual’s gait and, as the disease progresses, it signi...

    Authors: Helia Mahzoun Alzakerin, Yannis Halkiadakis and Kristin D. Morgan

    Citation: BMC Neurology 2019 19:316

    Content type: Research article

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  16. Endovascular treatment (EVT) is now considered the gold standard for select patient populations with anterior circulation stroke; however, data on the treatment of posterior circulation stroke are less clear. ...

    Authors: Xuan Sun, Xu Tong, Feng Gao, Huiting Lao and Zhongrong Miao

    Citation: BMC Neurology 2019 19:315

    Content type: Research article

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  17. The relevance of regular moderate to intense exercise for ameliorating psychomotor symptoms in persons with multiple sclerosis (pwMS) is becoming increasingly evident. Over the last two decades, emerging evide...

    Authors: Sebastian Proschinger, Niklas Joisten, Annette Rademacher, Marit L. Schlagheck, David Walzik, Alan J. Metcalfe, Max Oberste, Clemens Warnke, Wilhelm Bloch, Alexander Schenk, Jens Bansi and Philipp Zimmer

    Citation: BMC Neurology 2019 19:314

    Content type: Study protocol

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  18. Many peripheral blood biomarkers are associated with glioma grade, but eosinophils (Eo) are scarcely reported. This study assessed preoperative peripheral eosinophil levels and other peripheral biomarkers pres...

    Authors: Zhenxing Huang, Liang Wu, Zonggang Hou, Pengfei Zhang, Gen Li and Jian Xie

    Citation: BMC Neurology 2019 19:313

    Content type: Research article

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  19. Vertebral artery dissection (VAD) may cause cerebral ischemia and impair quality of life (QOL) despite of good functional outcome. The aim of this study was the multimodal analysis of patient characteristics a...

    Authors: Rainer J. Strege, Reinhard Kiefer and Manfred Herrmann

    Citation: BMC Neurology 2019 19:312

    Content type: Research article

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  20. Primary central nervous system lymphoma (PCNSL) is a rare, malignant, non-Hodgkin’s lymphoma of the brain, leptomeninges, and rarely the spinal cord. PCNSL has characteristic magnetic resonance imaging (MRI) f...

    Authors: Seung-Ho Jeon, Mi-Kyoung Kang, Seung Jae Lee, Byoung-Soo Shin and Hyun Goo Kang

    Citation: BMC Neurology 2019 19:311

    Content type: Case report

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  21. The mechanisms underlying the online modulation of motor speech in Parkinson’s disease (PD) have not been determined. Moreover, medical and rehabilitation interventions for PD-associated motor speech disorder ...

    Authors: Ying Liu, Yuchang Gui, Jincui Hu, Shanshan Liang, Sixia Mo, Yuanfang Zhou, Yujian Li, Fengkun Zhou and Jianwen Xu

    Citation: BMC Neurology 2019 19:309

    Content type: Research article

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  22. Status epilepticus (SE) is an emergency neurological disorder that affects quality of life and is associated with high mortality risk. Three scores have been developed to predict the risk of in-hospital death, bu...

    Authors: Prapassara Sirikarn, Porjai Pattanittum and Somsak Tiamkao

    Citation: BMC Neurology 2019 19:307

    Content type: Research article

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  23. Treatment with anticoagulants, including direct oral anticoagulants (DOACs), should be considered for patients diagnosed with atrial fibrillation (AF) deemed at risk of ischaemic stroke. There are limited real...

    Authors: Yaqoob Bhat, Anand Dixit, Amit Mistri, Bhavini Patel, Sadat Haider Quoraishi and James Uprichard

    Citation: BMC Neurology 2019 19:306

    Content type: Study protocol

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  24. Progressive Supranuclear Palsy (PSP) is the most frequent form of atypical Parkinsonism. Although there is preliminary evidence for the benefits of gait rehabilitation, balance training and oculomotor exercise...

    Authors: Susan C. Slade, Martin Underwood, Jennifer L. McGinley and Meg E. Morris

    Citation: BMC Neurology 2019 19:305

    Content type: Research article

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  25. Paraneoplastic limbic encephalitis (PLE) is a rare autoimmune neurological syndrome observed in cancer patients. PLE is difficult to diagnose and presents a variable response to treatment, depending on the cha...

    Authors: Raffaele Longo, Marc Wagner, Benjamin Savenkoff, Mathilde Chastenet de Castaing, Guillaume Desiro, Zead Tubail, Laurent Hennequin, Sinan Ben Mahmoud, Nathalie Marcon, Philippe Quetin, Marco Campitiello and Francesca Plastino

    Citation: BMC Neurology 2019 19:304

    Content type: Case report

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  26. Visual field defects caused by injury to Meyer’s loop (ML) are common in patients undergoing anterior temporal lobectomy during epilepsy surgery. Evaluation of the anatomical shapes of the curving, fanning and...

    Authors: Yong-Zhi Shan, Zhen-Ming Wang, Xiao-Tong Fan, Hua-Qiang Zhang, Lian-Kun Ren, Peng-Hu Wei and Guo-Guang Zhao

    Citation: BMC Neurology 2019 19:302

    Content type: Research article

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  27. McLeod syndrome is a rare X-linked recessive acanthocytosis associated with neurological manifestations including progressive chorea, cognitive impairment, psychiatric disturbances, seizures, and sensorimotor ...

    Authors: Takenobu Murakami, Dan Abe, Hideyuki Matsumoto, Ryo Tokimura, Mitsunari Abe, Amanda Tiksnadi, Shunsuke Kobayashi, Chikako Kaneko, Yuka Urata, Masayuki Nakamura, Akira Sano and Yoshikazu Ugawa

    Citation: BMC Neurology 2019 19:301

    Content type: Case report

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  28. The benefit of intravenous thrombolysis (IVT) for acute ischemic stroke is time dependent. Despite great effort, the median door-to-needle time (DNT) was 60 min at the United States stroke centers. We investig...

    Authors: Demi Tran, Zhu Zhu, Mohammad Shafie, Hermelinda Abcede, Dana Stradling and Wengui Yu

    Citation: BMC Neurology 2019 19:300

    Content type: Research article

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  29. Neologisms are commonly encountered in patients with acute cerebrovascular diseases, particularly in those with Wernicke’s aphasia. However, few studies have investigated primary progressive aphasia with neolo...

    Authors: Hiroyuki Watanabe, Manabu Ikeda and Etsuro Mori

    Citation: BMC Neurology 2019 19:299

    Content type: Case report

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  30. Stroke-associated pneumonia (SAP) is a common complication of cerebrovascular disease. The A2DS2 score has been used to predict the risk of SAP. However, hyperglycemia is not included in this scale. The purpose o...

    Authors: Yang Li, Yu Zhang, Liansheng Ma, Xiaoyuan Niu and Junsen Chang

    Citation: BMC Neurology 2019 19:298

    Content type: Research article

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  31. A huge spherical intracranial mass can sometimes be misdiagnosed, due to the lack of typical radiographic features. Thrombosed giant intracranial aneurysms (GIAs) are an uncommon but still a possible different...

    Authors: Mehdi Chihi, Ramazan Jabbarli, Oliver Gembruch, Sarah Teuber-Hanselmann, Marvin Darkwah Oppong, Daniela Pierscianek, Alexander Radbruch, Martin Glas, Mark Stettner and Ulrich Sure

    Citation: BMC Neurology 2019 19:297

    Content type: Case report

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  32. Glioma is the most common primary malignant brain tumor with high mortality and poor prognosis. Our aim was to clarify the correlation between Kinase-anchored protein 6 (AKAP6) gene polymorphisms and glioma susce...

    Authors: Ming Zhang, Yonglin Zhao, Junjie Zhao, Tingqin Huang and Yuan Wu

    Citation: BMC Neurology 2019 19:296

    Content type: Research article

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  33. Transient ischemic attack (TIA) patients are at high risk of recurrent vascular events; timely management can reduce that risk by 70%. The Protocol-guided Rapid Evaluation of Veterans Experiencing New Transien...

    Authors: D. M. Bravata, L. J. Myers, B. Homoya, E. J. Miech, N. A. Rattray, A. J. Perkins, Y. Zhang, J. Ferguson, J. Myers, A. J. Cheatham, L. Murphy, B. Giacherio, M. Kumar, E. Cheng, D. A. Levine, J. J. Sico…

    Citation: BMC Neurology 2019 19:294

    Content type: Study protocol

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  34. Neurological disorders are an economic and public health burden which requires efficient and adequate medical resources. Currently, little is known about the status of the quality of neurological care services...

    Authors: Jun-Fang Zhang, Meng-Yao Qiu, Yu-Lei Zhang, Xi-Xi Wang, Guo-Ping Wang, Yu Geng, Ke-Zhong Zhang, Kan Fang and Yun-Cheng Wu

    Citation: BMC Neurology 2019 19:293

    Content type: Research article

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  35. Antiepileptic drug (AED) induced dyskinesia is an unusual manifestation in the medical field. In the previous case reports describing first generation-AED related involuntary movements, the authors suggested t...

    Authors: Soo Hwan Yim, Yun Ho Choi, Kyoung Heo and Kyoo ho Cho

    Citation: BMC Neurology 2019 19:292

    Content type: Case report

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  36. Mutations of cyclooxygenase gene (COX gene) may increase the susceptibility of ischemic stroke. We investigated five variants (rs5788, rs1330344, rs3842788, rs20417, and rs689466) of two COX genes in order to ...

    Authors: Lei Zhao, Jinghuan Fang, Muke Zhou, Jie Zhou, Lihua Yu, Ning Chen and Li He

    Citation: BMC Neurology 2019 19:291

    Content type: Research article

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  37. In this paper, seizure types, and epilepsy syndromes are elucidated as per ILAE (2010) classification. A brief outline of the antiepileptic drug regimens used and the outcome of seizure control in a two -year ...

    Authors: Inaam N. Mohamed, Maha A. Elseed, Somia Mohamed, Ali Alsir, Emtinan K. Hamid, Ilham M. Omer, Sara M. Elsadig, Yasmin M. Gerais, Abdelgadir H. Osman, Aisha M. Bakhiet and Ahlam A. Hamed

    Citation: BMC Neurology 2019 19:290

    Content type: Research article

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  38. Ischemia-reperfusion (I/R)-induced vascular dysfunction is the main factor to acute ischemic stroke. Sirt3 is one of the sirtuin family members, which plays an important role in the development of neurological...

    Authors: Zhenzhen Zhao, Xiaoxiu Zhang, Yuanqiang Dai, Ke Pan, Yu Deng, Yan Meng and Tao Xu

    Citation: BMC Neurology 2019 19:289

    Content type: Research article

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  39. Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of unknown cause involving the brain and accompanied by prominent eosinophilia. Intracardiac thrombosis is a major cardiac com...

    Authors: Kenichiro Hira, Hideki Shimura, Riyu Kamata, Masashi Takanashi, Akane Hashizume, Keiji Takahashi, Mizuho Sugiyama, Hiroshi Izumi, Nobutaka Hattori and Takao Urabe

    Citation: BMC Neurology 2019 19:288

    Content type: Case report

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  40. Fingolimod (Gilenya®) is approved for relapsing forms of multiple sclerosis in the USA. Owing to transient heart-rate effects when initiating fingolimod, eligible patients undergo precautionary baseline assess...

    Authors: Brandon Brown, Jamie L. Weiss, Scott Kolodny, Xiangyi Meng, Ian M. Williams and John A. Osborne

    Citation: BMC Neurology 2019 19:287

    Content type: Research article

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    The Correction to this article has been published in BMC Neurology 2019 19:336

  41. Some studies have looked at the age at menarche and risk of Multiple Sclerosis (MS).We aimed to conduct a systematic review and meta-analysis to estimate a pooled odds ratio of developing MS by increasing age ...

    Authors: Amirreza Azimi, Sara Hanaei, Mohammad Ali Sahraian, Mehdi Mohammadifar, Sreeram V. Ramagopalan and Mahsa Ghajarzadeh

    Citation: BMC Neurology 2019 19:286

    Content type: Research article

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  42. Capsular warning syndrome (CWS) is a rare clinical syndrome, which is defined as a recurrent transient lacunar syndrome. The mechanism and clinical management of CWS remain unclear. The aim of the study was to...

    Authors: Lanying He, Ronghua Xu, Jian Wang, Lili Zhang, Lijuan Zhang, Fangfang Zhou and Weiwei Dong

    Citation: BMC Neurology 2019 19:285

    Content type: Research article

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  43. Cerebral infarction occurs when the arteries to brain are obstructed, and motor impairment contralateral to responsible lesion is commonly recognized. Few studies have profiled the characteristics of cases wit...

    Authors: Zhe-Ren Tan, Chen Zhang and Fa-Fa Tian

    Citation: BMC Neurology 2019 19:279

    Content type: Research article

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  44. Wilson disease (WD) is genetically induced failure of copper metabolism which can be successfully treated with pharmacological agents. The prognosis for survival in most WD patients is favorable if diagnosis a...

    Authors: Wojciech Masełbas, Anna Członkowska, Tomasz Litwin and Maciej Niewada

    Citation: BMC Neurology 2019 19:278

    Content type: Research article

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