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  1. Research article

    Neuropathy-specific alterations in a Mexican population of diabetic patients

    Neuropathy is one of the major complications of type 2 diabetes mellitus. Our first aim was to determine the clinical characteristics of a population of diabetic patients with different types of neuropathy. Ou...

    Angélica Carbajal-Ramírez, Rebeca García-Macedo, Carlos Manlio Díaz-García, Carmen Sanchez-Soto, Araceli Méndez Padrón, Jorge Escobedo de la Peña, Miguel Cruz and Marcia Hiriart

    BMC Neurology 2017 17:161

    Published on: 25 August 2017

  2. Debate

    Can brain impermeable BACE1 inhibitors serve as anti-CAA medicine?

    Cerebral amyloid angiopathy (CAA) is characterized by the deposition of ß-amyloid peptides (Aß) in and surrounding the wall of microvasculature in the central nervous system, together with parenchymal amyloid ...

    Jian-Ming Li, Li-Ling Huang, Fei Liu, Bei-Sha Tang and Xiao-Xin Yan

    BMC Neurology 2017 17:163

    Published on: 25 August 2017

  3. Research article

    Feasibility and diagnostic accuracy of point-of-care handheld echocardiography in acute ischemic stroke patients – a pilot study

    Standard echocardiography (SE) is an essential part of the routine diagnostic work-up after ischemic stroke (IS) and also serves for research purposes. However, access to SE is often limited. We aimed to asses...

    Peter Kraft, Anna Fleischer, Silke Wiedmann, Viktoria Rücker, Daniel Mackenrodt, Caroline Morbach, Uwe Malzahn, Christoph Kleinschnitz, Stefan Störk and Peter U. Heuschmann

    BMC Neurology 2017 17:159

    Published on: 11 August 2017

  4. Research article

    Patient satisfaction with ExtaviPro™ 30G, a new auto-injector for administering interferon β-1b in multiple sclerosis: results from a real-world, observational EXCHANGE study

    Patients with multiple sclerosis (MS) receiving long-term, subcutaneous interferon β-1b (IFN β-1b; Extavia®) often experience injection-site reactions and injection-site pain, which together with other side-ef...

    Frank A. Hoffmann, Anastasiya Trenova, Miguel A. Llaneza, Johannes Fischer, Giacomo Lus, Dorothea von Bredow, Núria Lara, Elaine Lam, Marlies Van Hoef and Rajesh Bakshi

    BMC Neurology 2017 17:156

    Published on: 9 August 2017

  5. Case report

    Subarachnoid small vein occlusion due to inflammatory fibrosis—a possible mechanism for cerebellar infarction in cryptococcal meningoencephalitis: a case report

    Cryptococcal meningoencephalitis (CM) causes cerebral infarction, typically, lacunar infarction in the basal ganglia. However, massive cerebral infarction leading to death is rare and its pathophysiology is un...

    Yoshiteru Shimoda, Satoru Ohtomo, Hiroaki Arai, Takashi Ohtoh and Teiji Tominaga

    BMC Neurology 2017 17:157

    Published on: 9 August 2017

  6. Research article

    Association between multiple sclerosis, cancer risk, and immunosuppressant treatment: a cohort study

    The association between multiple sclerosis (MS) and cancer has long been investigated with conflicting results. Several reports suggest an increased cancer risk among MS patients treated with immunosuppressant...

    Paolo Ragonese, Paolo Aridon, Giulia Vazzoler, Maria Antonietta Mazzola, Vincenzina Lo Re, Marianna Lo Re, Sabrina Realmuto, Simona Alessi, Marco D’Amelio, Giovanni Savettieri and Giuseppe Salemi

    BMC Neurology 2017 17:155

    Published on: 8 August 2017

  7. Research article

    Effectiveness, safety and health-related quality of life of multiple sclerosis patients treated with fingolimod: results from a 12-month, real-world, observational PERFORMS study in the Middle East

    Evidence on the use of fingolimod in real-world clinical practice and data on patient-reported health-related quality of life (HRQoL) in countries such as the Middle East are sparse. The Prospective Evaluation...

    Anat Achiron, Hany Aref, Jihad Inshasi, Mohamad Harb, Raed Alroughani, Mahendra Bijarnia, Kathryn Cooke and Ozgur Yuksel

    BMC Neurology 2017 17:150

    Published on: 7 August 2017

  8. Research article

    Outcome of MS relapses in the era of disease-modifying therapy

    In multiple sclerosis (MS), neurological disability results from incomplete remission of relapses and from relapse-independent progression. Intravenous high dose methylprednisolone (IVMP) is the established st...

    Muriel Stoppe, Maria Busch, Luise Krizek and Florian Then Bergh

    BMC Neurology 2017 17:151

    Published on: 7 August 2017

  9. Research article

    Prevalence of and risk factors for enlarged perivascular spaces in adult patients with moyamoya disease

    Enlarged perivascular spaces (EPVS) are often observed with magnetic resonance imaging in patients with small vessel disease. However, the risk factors, radiological features, and clinical relevance of EPVS in...

    Tomoyoshi Kuribara, Takeshi Mikami, Katsuya Komatsu, Hime Suzuki, Hirofumi Ohnishi, Kiyohiro Houkin and Nobuhiro Mikuni

    BMC Neurology 2017 17:149

    Published on: 4 August 2017

  10. Case report

    Effectiveness of spinal cord stimulation for painful camptocormia with Pisa syndrome in Parkinson’s disease: a case report

    Spinal cord stimulation (SCS) has recently been reported to be effective for truncal postural abnormalities such as camptocormia and Pisa syndrome in Parkinson’s disease. In this case report, we describe a cas...

    Hisanao Akiyama, Saki Nukui, Masashi Akamatu, Yasuhiro Hasegawa, Osamu Nishikido and Soichiro Inoue

    BMC Neurology 2017 17:148

    Published on: 3 August 2017

  11. Research article

    Peripheral blood lymphocytes immunophenotyping predicts disease activity in clinically isolated syndrome patients

    Clinically isolated syndrome (CIS) represents first neurological symptoms suggestive of demyelinating lesion in the central nervous system (CNS). Currently, there are no sufficient immunological or genetic mar...

    Helena Posová, Dana Horáková, Václav Čapek, Tomáš Uher, Zdenka Hrušková and Eva Havrdová

    BMC Neurology 2017 17:145

    Published on: 28 July 2017

  12. Research article

    Comparison of neuropsychiatric symptoms and diffusion tensor imaging correlates among patients with subcortical ischemic vascular disease and Alzheimer’s disease

    The causes of behavioral and psychological symptoms of dementia (BPSD) vary according to the dementia subtype and associated neuropathology. The present study aimed to (i) compare BPSD between patients with su...

    Min-Chien Tu, Wen-Hui Huang, Yen-Hsuan Hsu, Chung-Ping Lo, Jie Fu Deng and Ching-Feng Huang

    BMC Neurology 2017 17:144

    Published on: 28 July 2017

  13. Research article

    Evaluation of speed-accuracy trade-off in a computer task in individuals with cerebral palsy: a cross-sectional study

    Individuals with Cerebral Palsy (CP) present with sensorimotor dysfunction which make the control and execution of movements difficult. This study aimed to verify the speed-accuracy trade-off in individuals wi...

    Deborah Cristina Gonçalves Luiz Fernani, Maria Tereza Artero Prado, Talita Dias da Silva, Thais Massetti, Luiz Carlos de Abreu, Fernando Henrique Magalhães, Helen Dawes and Carlos Bandeira de Mello Monteiro

    BMC Neurology 2017 17:143

    Published on: 27 July 2017

  14. Research article

    Clinical and electrophysiological features of post-traumatic Guillain-Barré syndrome

    Post-traumatic Guillain-Barré syndrome (GBS) is a rarely described potentially life-threatening cause of weakness. We sought to elucidate the clinical features and electrophysiological patterns of post-traumat...

    Xiaowen Li, Jinting Xiao, Yanan Ding, Jing Xu, Chuanxia Li, Yating He, Hui Zhai, Bingdi Xie and Junwei Hao

    BMC Neurology 2017 17:142

    Published on: 27 July 2017

  15. Research article

    Comparative assessment of clinical rating scales in Wilson’s disease

    Wilson’s disease (WD) is an autosomal recessive disorder of copper metabolism resulting in multifaceted neurological, hepatic, and psychiatric symptoms. The objective of the study was to comparatively assess t...

    Hanna M. Volpert, Jan Pfeiffenberger, Jan B. Gröner, Wolfgang Stremmel, Daniel N. Gotthardt, Mark Schäfer, Karl Heinz Weiss and Markus Weiler

    BMC Neurology 2017 17:140

    Published on: 21 July 2017

  16. Research article

    Serum melatonin levels in survivor and non-survivor patients with traumatic brain injury

    Circulating levels of melatonin in patients with traumatic brain injury (TBI) have been determined in a little number of studies with small sample size (highest sample size of 37 patients) and only were report...

    Leonardo Lorente, María M. Martín, Pedro Abreu-González, Antonia Pérez-Cejas, Luis Ramos, Mónica Argueso, Jordi Solé-Violán, Juan J. Cáceres, Alejandro Jiménez and Victor García-Marín

    BMC Neurology 2017 17:138

    Published on: 19 July 2017

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