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  1. Growing evidence suggests that vascular risk factors, especially hypertension, relate not only to cardiovascular disease but also to cognitive impairment. However, the impact of pulse pressure on cognitive fun...

    Authors: Ryo Mizuhara, Shingo Mitaki, Masahiro Takamura, Satoshi Abe, Keiichi Onoda, Shuhei Yamaguchi and Atsushi Nagai
    Citation: BMC Neurology 2022 22:137
  2. Extracorporeal circulation (ECC) is now being increasingly used in critical care settings. Epileptic seizures are a recognized but under reported complication in patients receiving this care. Acute symptomatic...

    Authors: Matteo Pugnaghi, Francesco Cavallieri, Mauro Zennaro, Marialuisa Zedde, Romana Rizzi, Davide Gabbieri and Franco Valzania
    Citation: BMC Neurology 2022 22:136
  3. Diabetic striatopathy is a rare neurological manifestation of nonketotic hyperglycemia that presents with contralateral hemichorea-hemiballismus. Presentation with concurrent seizures is rarely reported.

    Authors: Abeer Sabry Safan, Omna Sharma, Muna Almasri, Ashton Ian D’Souza and Omer Suliman
    Citation: BMC Neurology 2022 22:133
  4. Large vessel occlusion (LVO) strokes are best treated with rapid endovascular therapy (EVT). There are two routes that LVO stroke patients can take to EVT therapy when transported by EMS: primary transport (am...

    Authors: Derek L. Isenberg, Kevin A. Henry, Adam Sigal, Traci Deaner, Jason T. Nomura, Kathleen A. Murphy, Derek Cooney, Susan Wojcik, Ethan S. Brandler, Alexander Kuc, Gerard Carroll, Chadd K. Kraus, Judy B. Shahan, Joseph Herres, Daniel Ackerman and Nina T. Gentile
    Citation: BMC Neurology 2022 22:132

    The Correction to this article has been published in BMC Neurology 2022 22:171

  5. Post herpes simplex virus (HSV) autoimmune encephalitis has been reported mainly in association with NMDA receptor antibodies, however, never with Caspr2 antibodies.

    Authors: Klaus Berek, Ronny Beer, Astrid Grams, Raimund Helbok, Anna Lindner, Bettina Pfausler, Alois Schiefecker, Florian Deisenhammer and Harald Hegen
    Citation: BMC Neurology 2022 22:131
  6. Type 2 diabetes mellitus (T2DM) affects the occurrence and prognosis of acute ischemic stroke (AIS). However, the impact of diabetes on thrombus characteristics is unclear. The relationship between the composi...

    Authors: Qun Gao, Peng Qi, Junjie Wang, Shen Hu, Ximeng Yang, Jingwen Fan, Ling Li, Yao Lu, Jun Lu, Juan Chen and Daming Wang
    Citation: BMC Neurology 2022 22:130
  7. The COVID-19 pandemic has forced lockdowns and declarations of states of emergency, resulting in marked changes to daily life such as dietary habits in many countries. Though serum omega-3 polyunsaturated fatt...

    Authors: Kenichiro Hira, Yuji Ueno, Nobukazu Miyamoto, Sho Nakajima, Chikage Kijima and Nobutaka Hattori
    Citation: BMC Neurology 2022 22:128
  8. Patients with brain tumours often present with non-specific symptoms. Correctly identifying who to prioritise for urgent brain imaging is challenging. Brain tumours are amongst the commonest cancers diagnosed ...

    Authors: Karolis Zienius, Mio Ozawa, Willie Hamilton, Will Hollingworth, David Weller, Lorna Porteous, Yoav Ben-Shlomo, Robin Grant and Paul M. Brennan
    Citation: BMC Neurology 2022 22:127
  9. Migraine patients have musculoskeletal disorders and pain in the cervical. And, despite the pathophysiology demonstrating the relationship between migraine and the cervical spine, the effectiveness of cranioce...

    Authors: Mariana Tedeschi Benatto, Lidiane Lima Florencio, Marcela Mendes Bragatto, Fabíola Dach, César Fernández-de-las-Peñas and Débora Bevilaqua-Grossi
    Citation: BMC Neurology 2022 22:126
  10. Previous studies have revealed that low frequency repeated transcranial magnetic stimulation (rTMS) on the contralesional primary motor cortex (cM1) is less effective in severe stroke patients with poor neural...

    Authors: Jiali Li, Hewei Wang, Yujian Yuan, Yunhui Fan, Fan Liu, Jingjing Zhu, Qing Xu, Lan Chen, Miao Guo, Zhaoying Ji, Yun Chen, Qiurong Yu, Tianhao Gao, Yan Hua, Mingxia Fan and Limin Sun
    Citation: BMC Neurology 2022 22:125
  11. To study the effects of subthalamic nucleus-deep brain stimulation (STN-DBS) on autonomic dysfunctions in Parkinson’s disease (PD) patients.

    Authors: Feng Zhang, Feng Wang, Cong-Hui Li, Ji-Wei Wang, Chun-Lei Han, Shi-Ying Fan, Dong-Mei Gao, Yu-Jing Xing, Chen Yang, Jian-Guo Zhang and Fan-Gang Meng
    Citation: BMC Neurology 2022 22:124
  12. The current multi-center, randomized, double-blind study was conducted among children with cerebral palsy (CP) to assess the safety and efficacy of umbilical cord blood mononuclear cell (UCB-MNC). We performed...

    Authors: Morteza Zarrabi, Masood Ghahvechi Akbari, Man Amanat, Anahita Majmaa, Ali Reza Moaiedi, Hadi Montazerlotfelahi, Masoumeh Nouri, Amir Ali Hamidieh, Reza Shervin Badv, Hossein Karimi, Ali Rabbani, Ali Mohebbi, Shahram Rahimi-Dehgolan, Rosa Rahimi, Ensieh Dehghan, Massoud Vosough…
    Citation: BMC Neurology 2022 22:123
  13. Biallelic pathogenic variants in the SCARB2 gene have been associated with action myoclonus-renal failure (AMRF) syndrome. Even though SCARB2 associated phenotype has been reported to include typical neurological...

    Authors: Burcu Atasu, Ayse Nur Ozdag Acarlı, Basar Bilgic, Betül Baykan, Erol Demir, Yasemin Ozluk, Aydin Turkmen, Ann-Kathrin Hauser, Gamze Guven, Hasmet Hanagasi, Hakan Gurvit, Murat Emre, Thomas Gasser and Ebba Lohmann
    Citation: BMC Neurology 2022 22:122
  14. Approximately half (55%) of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is known to show abnormal brain images, including high signal intensity in T2 or fluid attenuated inversion recovery (FLAIR) ...

    Authors: Dong Keun Son, Seong Min Cho, Han Uk Ryu, Byoung-Soo Shin and Hyun Goo Kang
    Citation: BMC Neurology 2022 22:121
  15. Multiple sclerosis (MS) is an inflammatory chronic disease that is characterized by an increased prevalence of adverse mental health outcomes in patients with MS (pwMS). The main aim of this study is to invest...

    Authors: Safanah AlSaeed, Nuha M. Alkhawajah, Mohsen Ayyash, Salman Aljarallah, Rola Alarieh and Amani Abu-Shaheen
    Citation: BMC Neurology 2022 22:120
  16. Transcranial direct current stimulation (tDCS) is a noninvasive brain stimulation to modulate cortical activity for improving motor function. However, the different tDCS applications for modulating cortical ac...

    Authors: Pei-Ling Wong, Yea-Ru Yang, Shun-Chang Tang, Shi-Fong Huang and Ray-Yau Wang
    Citation: BMC Neurology 2022 22:119
  17. Pallister-Hall syndrome (OMIM #146510) is a rare autosomal dominant condition caused by a mutation in the GLI3 gene. The cardinal feature of Pallister-Hall syndrome is the presence of hypothalamic hamartomas, ...

    Authors: Alessandra Consales, Giulia Ardemani, Claudia Maria Cinnante, Mariana Rita Catalano, Claudia Giavoli, Roberta Villa, Maria Iascone, Camilla Fontana, Maria Francesca Bedeschi and Monica Fumagalli
    Citation: BMC Neurology 2022 22:118
  18. Few research works have explored female sexual dysfunction (FSD) in patients with Neuromyelitis optica spectrum disorder (NMOSD) which remains an ignored disease symptom. This work aimed to describe the freque...

    Authors: Alaa ELmazny, Sara Salama, Mona Hussein, Eman Hany Elsebaie and Rehab Magdy
    Citation: BMC Neurology 2022 22:117
  19. Hereditary spastic paraplegias (HSPs) are progressively debilitating neurodegenerative disorders that follow heterogenous patterns of Mendelian inheritance. Available epidemiological evidence provides limited ...

    Authors: Geert Vander Stichele, Alexandra Durr, Grace Yoon, Rebecca Schüle, Craig Blackstone, Giovanni Esposito, Connor Buffel, Inês Oliveira, Christian Freitag, Stephane van Rooijen, Stéphanie Hoffmann, Leen Thielemans and Belinda S. Cowling
    Citation: BMC Neurology 2022 22:115
  20. Dementia with Lewy bodies (DLB) is the second most common dementia type in patients older than 65 years. Its atrophy patterns remain unknown. Its similarities to Parkinson's disease and differences from Alzhei...

    Authors: Eya Khadhraoui, Sebastian Johannes Müller, Niels Hansen, Christian Heiner Riedel, Philip Langer, Charles Timäeus, Jens Wiltfang, Caroline Bouter, Claudia Lange and Marielle Ernst
    Citation: BMC Neurology 2022 22:114
  21. Mechanical thrombectomy (MT) is an effective treatment for large-vessel occlusion in acute ischemic stroke, however, only some revascularized patients have a good prognosis. For stroke patients undergoing MT, ...

    Authors: Xiao-Guang Zhang, Jia-Hui Wang, Wen-Hao Yang, Xiao-Qiong Zhu, Jie Xue, Zhi-Zhang Li, Yu-Ming Kong, Liang Hu, Shan-Shan Jiang, Xu-Shen Xu and Yun-Hua Yue
    Citation: BMC Neurology 2022 22:111
  22. Cervical extension and flexion are presumably harmful to patients with degenerative cervical myelopathy (DCM) because they worsen medullary compression visible on dynamic magnetic resonance imaging (MRI). Dyna...

    Authors: Zhengran Yu, Jiacheng Chen, Xing Cheng, Dingxiang Xie, Yuguang Chen, Xuenong Zou and Xinsheng Peng
    Citation: BMC Neurology 2022 22:110
  23. The rehabilitation of paretic stroke patients uses a wide range of intervention programs to improve the function of impaired upper limb. A new rehabilitative approach, called action observation therapy (AOT) i...

    Authors: Antonino Errante, Donatella Saviola, Matteo Cantoni, Katia Iannuzzelli, Settimio Ziccarelli, Fabrizio Togni, Marcello Simonini, Carolina Malchiodi, Debora Bertoni, Maria Grazia Inzaghi, Francesca Bozzetti, Roberto Menozzi, Annamaria Quarenghi, Paola Quarenghi, Daniele Bosone, Leonardo Fogassi…
    Citation: BMC Neurology 2022 22:109
  24. Longitudinal extensive transverse myelitis is a rare and potentially life-threatening complication of chemoradiation. Certain chemotherapy agents have been proposed to increased neurotoxicity with chemoradiati...

    Authors: Travis Moodie, Ola Alshaqi and Abdul Alchaki
    Citation: BMC Neurology 2022 22:107
  25. Amyotrophic lateral sclerosis (ALS) is an incurable and fatal neurodegenerative disease; most ALS patients die within 3 to 5 years after symptom onset, usually as a consequence of respiratory failure. In the p...

    Authors: Qi-Jie Zhang, Jian-Chai Huang, Jia Chen, Wei Hu, Liu-Qing Xu and Qi-Fu Guo
    Citation: BMC Neurology 2022 22:105
  26. Inhere we evaluated the diagnostic utility of Doppler sonography (DS) of the anterior cerebral artery (ACA), middle cerebral artery (MCA) and the basilar arteries (BA) based on resistive index (RI) for the dia...

    Authors: Parisa Pishdad, Fatemeh Yarmahmoodi, Tannaz Eghbali, Peyman Arasteh and Seyyed Mostajab Razavi
    Citation: BMC Neurology 2022 22:104
  27. To establish content validity of a single-item, migraine-specific symptom severity questionnaire for completion by migraine patients, key family members (KFMs) of migraine patients, and Healthcare Professional...

    Authors: David Chandler, Marco Navetta, Shweta Shah, Jennifer Cline and Michael Phinney
    Citation: BMC Neurology 2022 22:103
  28. Acute motor and sensory axonal neuropathy (AMSAN) is a subtype of Guillain-Barré syndrome (GBS) differentiated by nerve conduction studies (NCS) and characterized by symmetric ascending paralysis often involvi...

    Authors: Hasan Alzuhaily, Eman khashaneh, Sanaa Albkhetan and Fatima Abbas
    Citation: BMC Neurology 2022 22:102
  29. Diagnosis of autism spectrum disorder (ASD) is generally made phenotypically and the hunt for ASD-biomarkers continues. The purpose of this study was to compare urine organic acids profiles of ASD versus typic...

    Authors: Zaib Un Nisa Khan, Prem Chand, Hafsa Majid, Sibtain Ahmed, Aysha Habib Khan, Azeema Jamil, Saba Ejaz, Ambreen Wasim, Khaleel Ahmad Khan and Lena Jafri
    Citation: BMC Neurology 2022 22:101
  30. To assess the clinical outcomes after endovascular thrombectomy (EVT) in elderly large vessel occlusion (LVO)-related acute ischemic stroke (AIS) patients with atrial fibrillation (AF).

    Authors: Jincheng Jiao, Sheng Liu, Chang Cui, Yuezhou Cao, Zhenyu Jia, Hailei Liu, Chendong Wang, Yu Hang, Heng Ni, Minglong Chen, Mingfang Li and Haibin Shi
    Citation: BMC Neurology 2022 22:100
  31. To test, in a two-arm, single center, superiority, randomized controlled trial, the effectiveness of and costs associated with a patient-initiated treatment model for people with hemifacial spasm (HFS) and ble...

    Authors: Sadie Lawes-Wickwar, Hayley McBain, Stefano Brini, Shashivadan P. Hirani, Catherine S. Hurt, Chris Flood, Nicola Dunlop, Dianne Solly, Bridget Crampton, Stanton P. Newman and Daniel G. Ezra
    Citation: BMC Neurology 2022 22:99
  32. Strokes have recently become a leading cause of disability among Thai people. Non-invasive brain stimulation (NIBS) seems to give promising results in stroke recovery when combined with standard rehabilitation...

    Authors: Sutthikit Pipatsrisawat, Jakkrit Klaphajone, Kittipong Kitisak, Somporn Sungkarat and Pakorn Wivatvongvana
    Citation: BMC Neurology 2022 22:98
  33. Neurological manifestations of Sars-CoV-2 infection have been described since March 2020 and include both central and peripheral nervous system manifestations. Neurological symptoms, such as headache or persis...

    Authors: Maria Beatrice Zazzara, Anna Modoni, Alessandra Bizzarro, Alessandra Lauria, Francesca Ciciarello, Cristina Pais, Vincenzo Galluzzo, Francesco Landi and Matteo Tostato
    Citation: BMC Neurology 2022 22:96
  34. Neuromyelitis optica spectrum disorders (NMOSD) is a rare inflammatory and demyelinating disease of the central nervous system (CNS) more frequent in women and Afro-descendants. No previous epidemiological or ...

    Authors: Thiago Gonçalves Fukuda, Ivã Taiuan Fialho Silva, Tayla Samanta Silva dos Santos, Marcos Baruch Portela Filho, Fernanda Ferreira de Abreu and Jamary Oliveira-Filho
    Citation: BMC Neurology 2022 22:95
  35. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects motor neurons selectively. In particular, weakness in respiratory and swallowing muscles occasionally causes aspirati...

    Authors: Temma Soga, Naoki Suzuki, Kengo Kato, Ai Kawamoto-Hirano, Yuko Kawauchi, Rumiko Izumi, Masaya Toyoshima, Shio Mitsuzawa, Tomomi Shijo, Kensuke Ikeda, Hitoshi Warita, Yukio Katori, Masashi Aoki and Masaaki Kato
    Citation: BMC Neurology 2022 22:94
  36. Mucopolysaccharidosis type III (Sanfilippo syndrome) is a lysosomal storage disorder, caused by a deficiency in the heparan-N-sulfatase enzyme involved in the catabolism of the glycosaminoglycan heparan sulfat...

    Authors: Delia Lorenz, Thomas Musacchio, Erdmute Kunstmann, Eva Grauer, Natalie Pluta, Annika Stock, Christian P. Speer and Helge Hebestreit
    Citation: BMC Neurology 2022 22:93
  37. Longitudinal cognitive testing is essential for developing novel preventive interventions for dementia and Alzheimer’s disease; however, the few available tools have significant practice effect and depend on a...

    Authors: Andrey Vyshedskiy, Rebecca Netson, Elisabeth Fridberg, Priyanka Jagadeesan, Matthew Arnold, Sophie Barnett, Anjali Gondalia, Victoria Maslova, Lauren de Torres, Simone Ostrovsky, Danijel Durakovic, Andrei Savchenko, Sienna McNett, Mikhail Kogan, Irene Piryatinsky and Dov Gold
    Citation: BMC Neurology 2022 22:92
  38. COVID-19, caused by a novel coronavirus SARS-CoV 2 has rapidly developed into pandemic. This infectious disease affecting mainly respiratory system may cause multiple systemic disorders. With increasing number...

    Authors: Natalia Morawiec, Daria Chyra, Adrianna Boroń, Bożena Adamczyk, Jerzy Jaroszewicz, Barbara Sobala-Szczygieł and Monika Adamczyk-Sowa
    Citation: BMC Neurology 2022 22:91
  39. The long-term use of an oral corticosteroid suppresses immunity. Here, we describe a case involving a patient with weakness in the bilateral lower extremities due to cytomegalovirus (CMV) lumbosacral polyradic...

    Authors: Jung Hae Yun, Ming-Yen Hsiao, Mathieu Boudier-Revéret and Min Cheol Chang
    Citation: BMC Neurology 2022 22:90
  40. Cranial autonomic symptoms (CASs) during migraine attacks are reported to be quite common regardless of ethnicity. In our previous study investigating 373 migraineurs, we found that 42.4% of them had CASs. The...

    Authors: Daisuke Danno, Johanna Wolf, Kumiko Ishizaki, Shoji Kikui, Koichi Hirata and Takao Takeshima
    Citation: BMC Neurology 2022 22:89
  41. Optimisation of dopaminergic therapy may alleviate fluctuation-related pain in Parkinson’s disease (PD). Opicapone (OPC) is a third-generation, once-daily catechol-O-methyltransferase inhibitor shown to be gen...

    Authors: K. Ray Chaudhuri, Per Odin, Joaquim J. Ferreira, Angelo Antonini, Olivier Rascol, Mónica M. Kurtis, Alexander Storch, Kirsty Bannister, Patrício Soares-da-Silva, Raquel Costa, Diogo Magalhães and José Francisco Rocha
    Citation: BMC Neurology 2022 22:88
  42. Blood pressure variability (BPV) is related to clinical outcome in acute ischemic stroke (AIS) treated with reperfusion therapy, but still is not included in clinical practice. This study aims to associate BPV...

    Authors: Jingcui Qin, Qing He and Zhijun Zhang
    Citation: BMC Neurology 2022 22:87
  43. Muscle ultrasonography has been increasingly recognized as a useful tool for detection of fasciculations. Separately, concordance between dominant hand and onset side has been reported in amyotrophic lateral s...

    Authors: Yo-ichi Suzuki, Kazumoto Shibuya, Sonoko Misawa, Tomoki Suichi, Atsuko Tsuneyama, Yuta Kojima, Keigo Nakamura, Hiroki Kano, Mario Prado and Satoshi Kuwabara
    Citation: BMC Neurology 2022 22:85

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