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  1. Authors: Tina Duong, Jessica Braid, Hannah Staunton, Aurelie Barriere, Fani Petridis, Johannes Reithinger, Rosangel Cruz, Jill Jarecki, Mencia De Lemus, Nicole Gusset, Ria Broekgaarden, Sharan Randhawa, Jessica Flynn, Rob Arbuckle, Sonia Reif, Lida Yang…

    Citation: BMC Neurology 2021 21:354

    Content type: Correction

    Published on:

    The original article was published in BMC Neurology 2021 21:143

  2. The aim of this study was to investigate whether default mode network (DMN) connectivity and brain white matter integrity at baseline were associated with severe cognitive impairments at baseline and poor cogn...

    Authors: Shigenori Kanno, Kun-ichi Ogawa, Hiroaki Kikuchi, Masako Toyoshima, Nobuhito Abe, Kazushi Sato, Koichi Miyazawa, Ryuji Oshima, Satoru Ohtomo, Hiroaki Arai, Satoshi Shibuya and Kyoko Suzuki

    Citation: BMC Neurology 2021 21:353

    Content type: Research

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  3. Rosai–Dorfman disease (RDD) is a rare, benign, idiopathic non-Langerhans cell histiocytosis. Cases of RDD in the CNS are extremely rare but lethal. RDD is thought to represent a reactive process. Recent studie...

    Authors: Huawei Jin, Zhenhua Yu, Tian Tian, Guoping Shen, Weian Chen, Miao Fan, Qun He, Fei Xu and Dawei Liu

    Citation: BMC Neurology 2021 21:352

    Content type: Case report

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  4. Weight gain (WG) is a frequently reported side effect of subthalamic deep brain stimulation; however, the underlying mechanisms remain unclear. The active contact locations influence the clinical outcomes of s...

    Authors: Katsuki Eguchi, Shinichi Shirai, Masaaki Matsushima, Takahiro Kano, Kazuyoshi Yamazaki, Shuji Hamauchi, Toru Sasamori, Toshitaka Seki, Kenji Hirata, Mayumi Kitagawa, Mika Otsuki, Tohru Shiga, Kiyohiro Houkin, Hidenao Sasaki and Ichiro Yabe

    Citation: BMC Neurology 2021 21:351

    Content type: Research

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  5. Asymptomatic carotid artery stenosis (aCAS) impairs haemodynamic and cognitive functions; however, the relationship between these changes and brain network connectivity remains largely unknown. This study aime...

    Authors: Shihao He, Ran Duan, Ziqi Liu, Cai Zhang, Tian Li, Yanchang Wei, Ning Ma and Rong Wang

    Citation: BMC Neurology 2021 21:350

    Content type: Research

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  6. We tried to evaluate the prevalence of premature discontinuation of antiplatelets and its affecting factors after ischemic stroke using large-sized representative national claims data.

    Authors: Seung Jae Kim, Oh Deog Kwon, Ho Chun Choi, Eung-Joon Lee, BeLong Cho and Dae Hyun Yoon

    Citation: BMC Neurology 2021 21:349

    Content type: Research

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  7. Autoimmune encephalitis (AE) is a rare inflammatory disorder characterized by important psychiatric and neurologic symptoms. The literature documents high rates of neuropsychological dysfunction in N-methyl D-...

    Authors: Laura Mori, William Campanella, Lucilla Vestito, Lucio Marinelli, Luana Benedetti, Leonardo Cocito and Carlo Trompetto

    Citation: BMC Neurology 2021 21:347

    Content type: Case report

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  8. Recombinant tissue plasminogen activator (rt-pa) is the first-line drug for the treatment of acute ischemic stroke, and can lead to some complications.There were rare reports of death due to acute pulmonary ed...

    Authors: Xue-Bing Chen, Dong Qu, Qing Zhang, Xia Yue and Dong-Fang Qiao

    Citation: BMC Neurology 2021 21:346

    Content type: Case report

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  9. The nature of COVID-19 pandemic measures has altered the clinical management of migraine, and has also created barriers to evaluate the impact of such measures of migraine patients. Using the Migraine Buddy sm...

    Authors: Yuji Kato, Weijie Poh, Zsolt Horvath, François Cadiou, Tomokazu Shimazu and Yuichi Maruki

    Citation: BMC Neurology 2021 21:345

    Content type: Research article

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  10. Idiopathic intracranial hypertension (IIH) is a disease which is difficult to diagnose and moreover difficult to treat. We developed a strategy for long-term telemonitoring of intracranial pressure (ICP), by i...

    Authors: Victor F. Velazquez Sanchez, Giath Al Dayri and Christoph A. Tschan

    Citation: BMC Neurology 2021 21:343

    Content type: Research article

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  11. Recent resting-state fMRI studies demonstrated functional dysconnectivity within the central pain matrix in migraineurs. This study aimed to investigate the spatial distribution and amplitude of low-frequency ...

    Authors: Ye Eun Kim, Min Kyung Kim, Sang-il Suh and Ji Hyun Kim

    Citation: BMC Neurology 2021 21:342

    Content type: Research

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  12. We aimed to explore the association of serum level of the nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) and its related inflammatory biomarkers (hypoxia induc...

    Authors: Yanan Wang, Hexiao Huang, Weihong He, Shihong Zhang, Ming Liu and Simiao Wu

    Citation: BMC Neurology 2021 21:341

    Content type: Research

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  13. The relationship between the HLA-B*1502 gene and maculopapular exanthema (MPE) induced by antiepileptic drugs (AEDs) has not yet been elucidated. In this study, we investigated the association between AED-indu...

    Authors: Nilupaer Shafeng, Deng-feng Han, Yun-fang Ma, Rena Abudusalamu and Binuer Ayitimuhan

    Citation: BMC Neurology 2021 21:340

    Content type: Research article

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  14. Resection of cerebral arteriovenous malformations (AVM) is technically demanding because of size, eloquent location or diffuse nidus. Controlled arterial hypotension (CAH) could facilitate haemostasis. We perf...

    Authors: Katharina Riedel, Marcus Thudium, Azize Boström, Johannes Schramm and Martin Soehle

    Citation: BMC Neurology 2021 21:339

    Content type: Research article

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  15. Epileptic seizures can be difficult to distinguish from other etiologies that cause cerebral hypoxia, especially cardiac diseases. Long QT syndrome (LQTS), especially LQTS type 2 (LQT2), frequently masquerades...

    Authors: Huicong Kang, Lili Lan, Yuchao Jia, Cun Li, Yongkang Fang, Suiqiang Zhu and Heidi Kirsch

    Citation: BMC Neurology 2021 21:338

    Content type: Case report

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  16. The aim of the current study was to examine multiple gait parameters obtained by wearable inertial sensors and their sensitivity to clinical status in early multiple sclerosis (MS). Further, a potential correl...

    Authors: Roy Müller, Daniel Hamacher, Sascha Hansen, Patrick Oschmann and Philipp M. Keune

    Citation: BMC Neurology 2021 21:337

    Content type: Research article

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  17. Craniopharyngioma (CP) is a slow-growing, benign tumor of the central nervous system located within the sellar and suprasellar regions. The tumor may extend from the suprasellar region to other areas. CPs are ...

    Authors: Xintao Cai, Zhixiang Sun, Yu Li, Dongqi Shao, Xialin Zheng, Yu Wang and Zhiquan Jiang

    Citation: BMC Neurology 2021 21:336

    Content type: Case report

    Published on:

  18. Mild cognitive impairment (MCI) is a common symptom in the patients with Parkinson’s disease (PD). The characteristics of cognitive impairment in PD are executive function (including working memory) and visuo-...

    Authors: Shoji Kawashima, Yoko Shimizu, Yoshino Ueki and Noriyuki Matsukawa

    Citation: BMC Neurology 2021 21:335

    Content type: Research

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  19. Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder characterized by dementia, tremor, episodic encephalopathy and autonomic nervous dysfunction. To date, vestibular migraine (VM)-li...

    Authors: Danhua Zhao, Sha Zhu, Qinlan Xu, Jianwen Deng, Zhaoxia Wang and Xianzeng Liu

    Citation: BMC Neurology 2021 21:334

    Content type: Case report

    Published on:

  20. Multiple sclerosis (MS) is a chronic autoimmune disease and is one of the most costly medical conditions that imposed families with catastrophic health expenditures. There is an increasing trend in using alter...

    Authors: Shadi Ziaie, Niloofar Namazi, Golnaz Afzal, Saghar Barati, Rezvaneh Mohebbi, Mahshad Mir, Hadi Esmaily and Gholamhossein Mehralian

    Citation: BMC Neurology 2021 21:333

    Content type: Research

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  21. The consequences of strict COVID-19 mobility restrictions on motor/non-motor features in Parkinson’s disease (PD) have not been systematically studied but worse mobility and quality of life have been reported....

    Authors: Raquel Luis-Martínez, Roberto Di Marco, Luca Weis, Valeria Cianci, Francesca Pistonesi, Alfonc Baba, Miryam Carecchio, Roberta Biundo, Chiara Tedesco, Stefano Masiero and Angelo Antonini

    Citation: BMC Neurology 2021 21:332

    Content type: Research article

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  22. Gait impairments are among the most common and impactful symptoms of Parkinson’s disease (PD). Recent technological advances aim to quantify these impairments using low-cost wearable systems for use in either ...

    Authors: Sara Alberto, Sílvia Cabral, João Proença, Filipa Pona-Ferreira, Mariana Leitão, Raquel Bouça-Machado, Linda Azevedo Kauppila, António P. Veloso, Rui M. Costa, Joaquim J. Ferreira and Ricardo Matias

    Citation: BMC Neurology 2021 21:331

    Content type: Research article

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  23. Spinal cord injury (SCI) is associated with autonomic imbalance and significant secondary conditions, including cardiac and brain dysfunction that adversely impact health and wellbeing. This study will investi...

    Authors: Ashley Craig, Ilaria Pozzato, Mohit Arora, James Middleton, Dianah Rodrigues, Candice McBain, Yvonne Tran, Glen M. Davis, Bamini Gopinath, Annette Kifley, Andrei Krassioukov, Jeffrey Braithwaite, Rebecca Mitchell, Sylvia M. Gustin, Jacob Schoffl and Ian D. Cameron

    Citation: BMC Neurology 2021 21:329

    Content type: Study protocol

    Published on:

  24. Spastic Paraplegia type 7 (SPG7) is one of the most common autosomal recessive Hereditary Spastic Paraplegias (HSP); Spastic Paraplegias (SPGs) can present as hereditary ataxias. However, ataxia is frequently ...

    Authors: Gabriele Bellini, Eleonora Del Prete, Elisa Unti, Daniela Frosini, Gabriele Siciliano and Roberto Ceravolo

    Citation: BMC Neurology 2021 21:328

    Content type: Case report

    Published on:

  25. Cognitive impairment is a common non-motor symptom in patients with Parkinson’s disease (PD). Mild cognitive impairment (MCI) is also prevalent in nondemented PD patients, even in newly diagnosed PD patients. ...

    Authors: Yanbing Hou, Qianqian Wei, Ruwei Ou, Lingyu Zhang, Xiaoqin Yuan, Qiyong Gong and Huifang Shang

    Citation: BMC Neurology 2021 21:327

    Content type: Research

    Published on:

  26. Parkinson’s Disease (PD) is a highly prevalent neurodegenerative disease whose incidence is increasing with an aging population. One of the most serious manifestations of PD is gait instability, leading to fal...

    Authors: Craig Horbinski, Katelyn B. Zumpf, Kathleen McCortney and Dean Eoannou

    Citation: BMC Neurology 2021 21:326

    Content type: Research

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  27. Despite trends towards the increased age of patients living with multiple sclerosis (MS), little is known about the response of older adults with MS to disease-modifying therapies (DMTs). Thus, a post-hoc analysi...

    Authors: Francesco Patti, Javier Nicolas Penaherrera, Lorissa Zieger and Eva-Maria Wicklein

    Citation: BMC Neurology 2021 21:324

    Content type: Research

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  28. Primary intracranial neuroendocrine tumors are exceedingly rare, with few cases in the literature. We present a case of a primary neuroendocrine carcinoma of the pineal gland, which is the second that has ever...

    Authors: Angela Cheng, Jane Barron, Oliver Holmes, Peter Bartlett, Gregory Jenkins and Melanie Seal

    Citation: BMC Neurology 2021 21:323

    Content type: Case report

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  29. Antiretroviral therapy (ART) development has reduced the severity of neurological complications of the human immunodeficiency virus (HIV), but they remain prevalent and need prompt recognition. Acute inflammat...

    Authors: Mariana Lopes, Patrícia Marques, Bruno Silva, Gonçalo Cruz, José Eduardo Serra, Eugenia Ferreira, Helena Alves and José Saraiva da Cunha

    Citation: BMC Neurology 2021 21:321

    Content type: Case report

    Published on:

  30. The cerebellum receives afferent signals from spinocerebellar pathways regulating lower limb movements. However, the longitudinal changes in the spinocerebellar pathway in the early stage of unilateral suprate...

    Authors: Gang Liu, Yaomin Guo, Chao Dang, Kangqiang Peng, Shuangquan Tan, Chuanmiao Xie, Shihui Xing and Jinsheng Zeng

    Citation: BMC Neurology 2021 21:320

    Content type: Research article

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  31. Antiplatelet drugs may prevent recurrent ischemic events after ischemic stroke but their relative effectiveness and harms still need to be clarified. Within this network meta-analysis we aimed to summarize the...

    Authors: Cinzia Del Giovane, Giorgio B. Boncoraglio, Lorenza Bertù, Rita Banzi and Irene Tramacere

    Citation: BMC Neurology 2021 21:319

    Content type: Research article

    Published on:

  32. Sedentary behaviour is associated with disease, but the molecular mechanisms are not understood. Valid biomarkers with predictive and explanatory properties are required. Therefore, we have investigated tradit...

    Authors: Katinka Nordheim Alme, Torunn Askim, Jörg Assmus, Tom Eirik Mollnes, Mala Naik, Halvor Næss, Ingvild Saltvedt, Per-Magne Ueland, Arve Ulvik and Anne-Brita Knapskog

    Citation: BMC Neurology 2021 21:318

    Content type: Research

    Published on:

  33. People with multiple sclerosis (MS) experience a wide range of unpredictable and variable symptoms. The symptomatology of MS has previously been reported in large sample registry studies; however, some symptom...

    Authors: S. Gustavsen, A. Olsson, H. B. Søndergaard, S. R. Andresen, P. S. Sørensen, F. Sellebjerg and A. Oturai

    Citation: BMC Neurology 2021 21:317

    Content type: Research article

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  34. Authors: Christopher Dardis, David Donner, Nader Sanai, Joanne Xiu, Sandeep Mittal, Sharon K. Michelhaugh, Manjari Pandey, Santosh Kesari, Amy B. Heimberger, Zoran Gatalica, Michael W. Korn, Ashley L. Sumrall and Surasak Phuphanich

    Citation: BMC Neurology 2021 21:316

    Content type: Publisher Correction

    Published on:

    The original article was published in BMC Neurology 2021 21:231

  35. Levels of self-reported health do not always correlate with levels of physical disability in stroke survivors. We aimed to explore what underlies the difference between subjective self-reported health and obje...

    Authors: Nahal Mavaddat, Euan Sadler, Lisa Lim, Kate Williams, Elizabeth Warburton, Ann Louise Kinmonth, Chris Mckevitt and Jonathan Mant

    Citation: BMC Neurology 2021 21:315

    Content type: Research article

    Published on:

  36. Peripheral neuropathy (PN) is a neurological complication of untreated Human Immunodeficiency Virus (HIV) infection or exposure to certain antiretroviral drugs. In Tanzania where HIV is a major public health p...

    Authors: Insiyah A Amiji, Helga E Naburi, Edward Kija and Livin P Mumburi

    Citation: BMC Neurology 2021 21:314

    Content type: Research

    Published on:

  37. SELENON (SEPN1)-related myopathy (SELENON-RM) is a rare congenital myopathy characterized by slowly progressive proximal muscle weakness, early onset spine rigidity and respiratory insufficiency. A muscular dy...

    Authors: Karlijn Bouman, Jan T. Groothuis, Jonne Doorduin, Nens van Alfen, Floris E. A. Udink ten Cate, Frederik M. A. van den Heuvel, Robin Nijveldt, Willem C. M. van Tilburg, Stan C. F. M. Buckens, Anne T. M. Dittrich, Jos M. T. Draaisma, Mirian C. H. Janssen, Erik-Jan Kamsteeg, Esmee S. B. van Kleef, Saskia Koene, Jan A. M. Smeitink…

    Citation: BMC Neurology 2021 21:313

    Content type: Study protocol

    Published on:

  38. Brain age is a biomarker that predicts chronological age using neuroimaging features. Deviations of this predicted age from chronological age is considered a sign of age-related brain changes, or commonly refe...

    Authors: Jo Wrigglesworth, Phillip Ward, Ian H. Harding, Dinuli Nilaweera, Zimu Wu, Robyn L. Woods and Joanne Ryan

    Citation: BMC Neurology 2021 21:312

    Content type: Research article

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  39. Cerebral microbleeds (CMBs) are detected on gradient-echo T2*-weighted magnetic resonance imaging (MRI). Clinically, CMBs are often detected after stroke, including in cases of intracerebral hemorrhage and isc...

    Authors: Toshihide Naganuma, Daijiro Kabata, Yoshiaki Takemoto, Junji Uchida and Ayumi Shintani

    Citation: BMC Neurology 2021 21:311

    Content type: Research

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  40. Extracranial carotid artery disease is considered a risk factor for developing acute cerebrovascular diseases. The paper suggests the “Stroke-Stop” formula as hypothesis for the determination of the risk of de...

    Authors: Іvan Kopolovets, Peter Berek, Peter Stefanic, Dmytro Lotnyk, Rastislav Mucha, Zdenka Hertelyova, Stefan Toth, Nadiya Boyko and Vladimir Sihotsky

    Citation: BMC Neurology 2021 21:310

    Content type: Research article

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  41. Multiple Sclerosis (MS) remains to be a public health challenge, due to its unknown biological mechanisms and clinical impacts on young people. The prevalence of this disease in Iran is reported to be 5.30 to ...

    Authors: Naeimehossadat Asmarian, Zahra Sharafi, Amin Mousavi, Reis Jacques, Ibon Tamayo, Marie-Abèle Bind, Marzie Abutorabi-zarchi, Mohammad Javad Moradian and Sadegh Izadi

    Citation: BMC Neurology 2021 21:309

    Content type: Research article

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  42. Tuberculous meningitis (TBM) is the most lethal form of tuberculosis worldwide. Data on critically ill TBM patients in the intensive care unit (ICU) of China are lacking. We tried to identify prognostic factor...

    Authors: Baobao Feng, Xiao Fei, Ying Sun, Xingguo Zhang, Deya Shang, Yi Zhou, Meiyan Sheng, Jiarui Xu, Wei Zhang and Wanhua Ren

    Citation: BMC Neurology 2021 21:308

    Content type: Research article

    Published on:

  43. To summarize the safety and effectiveness of high flow extracranial to intracranial saphenous vein bypass grafting in the treatment of complex intracranial aneurysms.

    Authors: Jibo Zhang, Yu Feng, Wenyuan Zhao, Kui Liu and Jincao Chen

    Citation: BMC Neurology 2021 21:307

    Content type: Technical advance

    Published on:

  44. The investigation of CO2 reactivity (CO2-CVR) is used in the setting of, e.g., traumatic brain injury (TBI). Transcranial color-coded duplex sonography (TCCD) is a promising bedside tool for monitoring cerebral h...

    Authors: Stephanie Klinzing, Federica Stretti, Alberto Pagnamenta, Markus Bèchir and Giovanna Brandi

    Citation: BMC Neurology 2021 21:305

    Content type: Research article

    Published on:

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