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  1. Valproate (VPA) is a commonly prescribed antiepileptic drug for patients experiencing epileptic seizures due to brain tumors. VPA increases radiation sensitivity in various tumor cells in vitro due to complex ...

    Authors: Jenny Stritzelberger, Jennifer Lainer, Stefanie Gollwitzer, Wolfgang Graf, Tina Jost, Johannes D. Lang, Tamara M. Mueller, Stefan Schwab, Rainer Fietkau, Hajo M. Hamer and Luitpold Distel

    Citation: BMC Neurology 2020 20:390

    Content type: Research article

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  2. Self-rated health (SRH) focuses on the patient’s own perception, and represents an important patient-reported outcome. The aim was to investigate SRH one to 5 years after stroke, follow the development over ti...

    Authors: Kerstin Bjälkefur, Salmir Nasic, Eric Bertholds, Katarina Jood and Åsa Rejnö

    Citation: BMC Neurology 2020 20:389

    Content type: Research article

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  3. Cerebral Palsy (CP) is a group of disorders that affect the development of movement and posture. CP results from injuries to the immature brain during the prenatal, perinatal, or postnatal stage of development...

    Authors: Diana Tajik-Parvinchi, Andrew Davis, Sophia Roth, Peter Rosenbaum, Sarah N. Hopmans, Aya Dudin, Geoffrey Hall and Jan Willem Gorter

    Citation: BMC Neurology 2020 20:388

    Content type: Research article

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  4. Globally, there is a growing use of Information and Communication Technology (ICT), including mobile phones, tablets and computers, which are being integrated into people’s daily activities. An ICT-based inter...

    Authors: Susanne Guidetti, Martha Gustavsson, Kerstin Tham, Magnus Andersson, Uno Fors and Charlotte Ytterberg

    Citation: BMC Neurology 2020 20:387

    Content type: Research article

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  6. Training with brain-computer interface (BCI) technology in the rehabilitation of patients after a stroke is rapidly developing. Numerous RCT investigated the effects of BCI training (BCIT) on recovery of motor...

    Authors: Antje Kruse, Zorica Suica, Jan Taeymans and Corina Schuster-Amft

    Citation: BMC Neurology 2020 20:385

    Content type: Research article

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  7. Endovascular treatment is the technique of choice for most intracranial aneurysms. However, the treatment of morphologically complex wide-necked aneurysms with an unfavorable anatomy is still a therapeutic cha...

    Authors: Juan David Molina-Nuevo, Lorena López-Martínez, María José Pedrosa-Jiménez, Enrique Juliá-Molla and Francisco Hernández-Fernández

    Citation: BMC Neurology 2020 20:384

    Content type: Research article

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  9. Glioblastoma (GBM) is known for its devastating intracranial infiltration and its unfavorable prognosis, while extracranial involvement is a very rare event, more commonly attributed to IDH wild-type (primary)...

    Authors: Jessica Rossi, Lucia Giaccherini, Francesco Cavallieri, Manuela Napoli, Claudio Moratti, Elisabetta Froio, Silvia Serra, Alessandro Fraternali, Reza Ghadirpour, Salvatore Cozzi, Patrizia Ciammella, Corrado Iaccarino, Rosario Pascarella, Franco Valzania and Anna Pisanello

    Citation: BMC Neurology 2020 20:382

    Content type: Case report

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  10. Although South Africa (SA) is facing a high prevalence of HIV infection, there is no literature from this region on a link between Bell’s palsy and HIV. The aim of this study was to identify the occurrence of ...

    Authors: Dali Magazi, Benjamin Longombenza, Siyazi Mda, Kees Van der Meyden, Marcus Motshwane, Mirabel Nanjoh and Olakunle Towobola

    Citation: BMC Neurology 2020 20:381

    Content type: Research article

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  11. Numerous studies on acute ischemic stroke (AIS) have been conducted at low-altitude regions, and the related findings have been used to guide clinical management. However, corresponding studies at high altitud...

    Authors: Yuxuan Lu, Cidan Zhuoga, Haiqiang Jin, Feiqi Zhu, Yuhua Zhao, Zhijie Ding, Shihua He, Ailian Du, Jun Xu, Jingjing Luo and Yongan Sun

    Citation: BMC Neurology 2020 20:380

    Content type: Research article

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  12. The prevalence of stroke recurrence, disability, and all-cause mortality of patients with minor ischemic stroke (MIS) remains problematic. The aim of the present study was to identify risk factors associated w...

    Authors: Zhongzhong Liu, Wenjuan Lin, Qingli Lu, Jing Wang, Pei Liu, Xuemei Lin, Fang Wang, Yaling Shi, Qing Wang, Guozheng Liu and Songdi Wu

    Citation: BMC Neurology 2020 20:379

    Content type: Research article

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  15. Ageing is associated with worse treatment outcome after traumatic brain injury (TBI). This association may lead to a self-fulfilling prophecy that affects treatment efficacy. The aim of the current study was t...

    Authors: Ola Skaansar, Cathrine Tverdal, Pål Andre Rønning, Karoline Skogen, Tor Brommeland, Olav Røise, Mads Aarhus, Nada Andelic and Eirik Helseth

    Citation: BMC Neurology 2020 20:376

    Content type: Research article

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  17. Percutaneous dilatational tracheostomy (PDT) has become a widely performed technique in neurocritical care, which is however known to be accompanied by some risks to the patient. The aim of this pilot study wa...

    Authors: Vera Spatenkova, Eckhard Teschner and Jaroslav Jedlicka

    Citation: BMC Neurology 2020 20:374

    Content type: Research article

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  18. The high morbidity, mortality, and disability rates of stroke constitute a heavy burden to the society. The level of understanding about stroke warning symptoms and first aid systems among community residents ...

    Authors: Xuemin Zhong, Jian Wang, Lanying He and Ronghua Xu

    Citation: BMC Neurology 2020 20:373

    Content type: Research article

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  19. Acute vertigo is a common presentation of inner ear disease. However, it can also be caused by more serious conditions, especially posterior circulation stroke. Differentiating between these two conditions by ...

    Authors: Naruchorn Kijpaisalratana, Pattaraporn Nimsamer, Ariya Khamwut, Sunchai Payungporn, Trairak Pisitkun, Aurauma Chutinet, Nattawan Utoomprurkporn, Stephen J. Kerr, Pakkawan Vongvasinkul and Nijasri C. Suwanwela

    Citation: BMC Neurology 2020 20:372

    Content type: Research article

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  20. Parkinson’s disease (PD) is a common neurodegenerative condition associated with a wide range of motor and non-motor symptoms. There has been increasing interest in the potential benefit of performing arts as ...

    Authors: Maxwell S. Barnish and Susannah M. Barran

    Citation: BMC Neurology 2020 20:371

    Content type: Research article

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  21. The artery of Percheron is an uncommon anatomic variant which supplies the bilateral paramedian thalami and rostral midbrain. While infarction of its vascular territory can result in a wide range of symptoms, ...

    Authors: Hannah E. Snyder, Sheliza Ali, Joanna Sue, Ayse Unsal, Crystal Fong and Zhihui Deng

    Citation: BMC Neurology 2020 20:370

    Content type: Case report

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  22. Room tilt illusion (RTI) is a rare symptom of higher vestibular dysfunction, consisting of a transient vertical rotation of the visual scene in the sagittal or coronal plane, most often 90o or 180o, without any a...

    Authors: Kathrine Arntzen and Karl B. Alstadhaug

    Citation: BMC Neurology 2020 20:369

    Content type: Case report

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  24. Dynamic somatosensory evoked potentials (DSSEP) can be used to disclose abnormalities of ascending sensory pathways at dynamic positions and diagnose cervical spondylotic myelopathy (CSM). However, radiographi...

    Authors: Zhengran Yu, Kaiyuan Lin, Jiacheng Chen, Kuan-Hung Chen, Wei Guo, Yuhu Dai, Yuguang Chen, Xuenong Zou and Xinsheng Peng

    Citation: BMC Neurology 2020 20:367

    Content type: Research article

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  25. Sturge-Weber syndrome (SWS) is primarily diagnosed in pediatric population, but clinical presentation in late adulthood is rarely reported. Evolution of radiological findings in the adulthood variant of SWS wi...

    Authors: Vetrivel Muralidharan, Gaetano Failla, Mario Travali, Tiziana Liliana Cavallaro and Marco Angelo Politi

    Citation: BMC Neurology 2020 20:366

    Content type: Case report

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  26. Transcranial magnetic stimulation (TMS) treatments have shown promise in improving arm recovery in stroke patients. Currently, little is known about patients’ experiences with repetitive TMS treatment, and thi...

    Authors: Eline CC van Lieshout, Lilliane D Jacobs, Maike Pelsma, Rick M Dijkhuizen and Johanna MA Visser-Meily

    Citation: BMC Neurology 2020 20:365

    Content type: Research article

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  27. In this pooled, post hoc analysis of a phase 2 trial and the phase 3 TEMSO, TOWER, and TENERE clinical trials, long-term efficacy and safety of teriflunomide were assessed in subgroups of patients with relapsi...

    Authors: Giancarlo Comi, Mark S. Freedman, José E. Meca-Lallana, Patrick Vermersch, Byoung Joon Kim, Alexander Parajeles, Keith R. Edwards, Ralf Gold, Houari Korideck, Jeffrey Chavin, Elizabeth M. Poole and Patricia K. Coyle

    Citation: BMC Neurology 2020 20:364

    Content type: Research article

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  28. Language barriers were reported to affect timely access to health care and outcome. The aim of this study was to investigate the effect of language disparity on quality benchmarks of acute ischemic stroke ther...

    Authors: Noriko Anderson, Afra Janarious, Shimeng Liu, Lisa A. Flanagan, Dana Stradling and Wengui Yu

    Citation: BMC Neurology 2020 20:363

    Content type: Research article

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  30. Idiopathic hypereosinophilic syndrome (IHES) is associated with various organ system dysfunctions. Neurologic abnormalities have been previously noted in this syndrome. Cerebral infarction secondary to occlusi...

    Authors: Quan-Fu Li, Qing Zhang, Yue-Fang Huang and Zheng-Xiang Zhang

    Citation: BMC Neurology 2020 20:361

    Content type: Case report

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  31. For large hemispheric infarction (LHI), malignant cerebral edema (MCE) is a life-threatening complication with a mortality rate approaching 80%. Establishing a convenient prediction model of MCE after LHI is v...

    Authors: Wenzhe Sun, Guo Li, Yang Song, Zhou Zhu, Zhaoxia Yang, Yuxi Chen, Jinfeng Miao, Xiaoyan Song, Yan Lan, Xiuli Qiu, Suiqiang Zhu and Yebin Fan

    Citation: BMC Neurology 2020 20:360

    Content type: Research article

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  32. Immune-mediated mechanisms substantially contribute to the Rasmussen encephalitis (RE) pathology, but for unknown reasons, immunotherapy is generally ineffective in patients who have already developed intracta...

    Authors: Zuzana Liba, Martina Vaskova, Josef Zamecnik, Jana Kayserova, Hana Nohejlova, Matyas Ebel, Jan Sanda, Gonzalo Alonso Ramos-Rivera, Klara Brozova, Petr Liby, Michal Tichy and Pavel Krsek

    Citation: BMC Neurology 2020 20:359

    Content type: Research article

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  33. The novel coronavirus (COVID-19) global pandemic is associated with an increased incidence of acute ischemic stroke (AIS) secondary to large vessel occlusion (LVO). The treatment of these patients poses unique...

    Authors: Ossama Yassin Mansour, Amer M. Malik and Italo Linfante

    Citation: BMC Neurology 2020 20:358

    Content type: Case report

    Published on:

  36. Paraneoplastic cerebellar degeneration (PCD) is a devastating paraneoplastic syndrome that occasionally occurs in patients with Hodgkin lymphoma (HL). Anti-Ma2 is a well-characterized onconeuronal antibody and...

    Authors: Ryoma Inui, Kenki Saito, Yoshimitsu Shimomura, Daisuke Yamashita, Michi Kawamoto and Takayuki Ishikawa

    Citation: BMC Neurology 2020 20:355

    Content type: Case report

    Published on:

  37. In acute large anterior circulation infarct patients with large core volume, we evaluated the role of optic nerve sheath diameter (ONSD) change rates in prediction of malignant progression.

    Authors: Seong-Joon Lee, Mun Hee Choi, Sung Eun Lee, Ji Hyun Park, Bumhee Park, Jin Soo Lee and Ji Man Hong

    Citation: BMC Neurology 2020 20:354

    Content type: Research article

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  38. Dynamic-related protein 1 (Drp1) is a key protein involved in the regulation of mitochondrial fission, and it could affect the dynamic balance of mitochondria and appears to be protective against neuronal inju...

    Authors: Zhong Luo, Jing Wang, Shirong Tang, Yongsu Zheng, Xuejiao Zhou, Fei Tian and Zucai Xu

    Citation: BMC Neurology 2020 20:353

    Content type: Research article

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  39. Moyamoya-like vasculopathy (MMV) and myosin heavy chain 9-related platelet disorders (MYH9-RPDs) or macrothrombocitopenias are rare syndromes. Their association is even more infrequent.

    Authors: Athena Cristina Ribigan, Raluca Stefania Badea, Alida Ciocan, Dana Stefan, Bogdan Casaru, Patricia Ioan, Florina Antochi and Ovidiu Băjenaru

    Citation: BMC Neurology 2020 20:352

    Content type: Case report

    Published on:

  40. Oculomotor nerve palsy (ONP) is a common symptom of posterior communicating artery aneurysm (PcomAA) that can lead to impaired eye movement and pupil dilation. Currently, surgical clipping and endovascular emb...

    Authors: Li-qiang Tian and Qing-xi Fu

    Citation: BMC Neurology 2020 20:351

    Content type: Research article

    Published on:

  41. Cognitive impairment may be correlated with cardiovascular dysautonomia, including blood pressure (BP) dysregulation, in Parkinson’s disease (PD), but the association between these factors in dementia with Lew...

    Authors: Hisayoshi Oka, Tadashi Umehara, Atsuo Nakahara and Hiromasa Matsuno

    Citation: BMC Neurology 2020 20:350

    Content type: Research article

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  42. Reversible posterior leukoencephalopathy syndrome (RPLS) is a rare and heterogeneous clinico-neuroradiological syndrome characterized by headache, altered mental status, seizures, and visual disturbances. Hype...

    Authors: Kuan-Ying Li, Ching-Fang Chien, Chin-Ling Tsai, Huang-Chi Chen, Meng-Ni Wu, Chiou-Lian Lai and Li-Min Liou

    Citation: BMC Neurology 2020 20:349

    Content type: Case report

    Published on:

  43. Stroke is a major cause of disability and stroke incidence increases with age. Stroke frequently results in permanent limitations of mobility, and, consequently, the need for the help of others in activities o...

    Authors: R. Rössler, S. A. Bridenbaugh, S. T. Engelter, R. Weibel, D. Infanger, E. Giannouli, A. Sofios, L. Iendra, E. Portegijs, T. Rantanen, L. Streese, H. Hanssen, R. Roth, A. Schmidt-Trucksäss, N. Peters and T. Hinrichs

    Citation: BMC Neurology 2020 20:348

    Content type: Study protocol

    Published on:

  45. Neurologists play an essential role in facilitating the patient’s process of living with Parkinson’s disease (PD). The Living with Chronic Illness Scale-PD (LW-CI-PD) is a unique available clinical tool that e...

    Authors: Leire Ambrosio, Carmen Rodriguez-Blazquez, Alba Ayala and Maria João Forjaz

    Citation: BMC Neurology 2020 20:346

    Content type: Research article

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  46. Hashimoto’s disease has reportedly been associated with stroke; however, cerebrovascular morphology and clinical course remain poorly documented. The present study aimed to determine the angiographic features ...

    Authors: Eika Hamano, Masaki Nishimura, Hisae Mori, Tetsu Satow and Jun C. Takahashi

    Citation: BMC Neurology 2020 20:345

    Content type: Research article

    Published on:

  48. Previous studies have shown that a single Coma-Recovery Scale-Revision (CRS-R) assessment can identify high rates of misdiagnosis by clinical consensus. The aim of this study was to investigate the proportion ...

    Authors: Jing Wang, Xiaohua Hu, Zhouyao Hu, Ziwei Sun, Steven Laureys and Haibo Di

    Citation: BMC Neurology 2020 20:343

    Content type: Research article

    Published on:

  50. Studies report rates of mild cognitive impairment (MCI) in spinal cord injury (SCI) range between 10 and 60%. This broad estimate of MCI in SCI is most likely a result of: (i) inconsistent operationalization o...

    Authors: Danielle Sandalic, Ashley Craig, Mohit Arora, Ilaria Pozzato, Grahame Simpson, Bamini Gopinath, Jasbeer Kaur, Sachin Shetty, Gerard Weber, Ian Cameron, Yvonne Tran and James Middleton

    Citation: BMC Neurology 2020 20:341

    Content type: Study protocol

    Published on:

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