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  1. Nowadays, few surgery analysis has been reported in cases of epilepsy after viral encephalitis(VE). Herein, this study was to evaluate the efficacy of surgery and capability of stereoelectroencephalography (SE...

    Authors: Yi-Ou Liu, Wen-Jing Zhou, Bo Hong, Tong Zhao and Yue-feng Wang

    Citation: BMC Neurology 2019 19:165

    Content type: Research article

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  2. Paroxysmal Sympathetic Hyperactivity (PSH) is a frequently observed condition among critically ill patients on intensive care units. According to different studies, PSH is associated with worse recovery and in...

    Authors: Alan Totikov, Melanie Boltzmann, Simone B. Schmidt and Jens D. Rollnik

    Citation: BMC Neurology 2019 19:162

    Content type: Research article

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  3. Epilepsy is a common neurological disease with substantial impact on the subject and their caretakers. This exploratory study identified barriers to care for persons living with epilepsy (PLWE) to develop a cu...

    Authors: Mark Kaddumukasa, Haddy Nalubwama, Martin N. Kaddumukasa, Samden Lhatoo, Nelson Sewankambo, Elly Katabira, Martha Sajatovic and Carol Blixen

    Citation: BMC Neurology 2019 19:161

    Content type: Research article

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  4. Our understanding of the etiology, pathophysiology, phenotypic diversity, and progression of Parkinson’s disease has stagnated. Consequently, patients do not receive the best care, leading to unnecessary disab...

    Authors: B. R. Bloem, W. J. Marks Jr., A. L. Silva de Lima, M. L. Kuijf, T. van Laar, B. P. F. Jacobs, M. M. Verbeek, R. C. Helmich, B. P. van de Warrenburg, L. J. W. Evers, J. intHout, T. van de Zande, T. M. Snyder, R. Kapur and M. J. Meinders

    Citation: BMC Neurology 2019 19:160

    Content type: Study protocol

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  5. Glatiramer acetate (GA) is one of the first therapies approved for multiple sclerosis (MS). We prospectively included and monitored drug-naïve and pre-treated MS patients who had been prescribed GA for 1 year,...

    Authors: Chiara Zecca, Giulio Disanto, Rosaria Sacco, Gianna C. Riccitelli and Claudio Gobbi

    Citation: BMC Neurology 2019 19:159

    Content type: Research article

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  7. Hereditary ataxia is a group of neurodegenerative diseases with progressive cerebellar ataxia of the gait and limbs as the main symptoms. The genetic patterns of the disease are diverse but it is mainly divide...

    Authors: Jiajun Chen, Yajuan Sun, Xiaoyang Liu and Jia Li

    Citation: BMC Neurology 2019 19:157

    Content type: Research article

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  8. Loss-of-function mutations in the CLCN2 gene were recently discovered to be a cause of a type of leukodystrophy named CLCN2-related leukoencephalopathy (CC2L), which is characterized by intramyelinic edema. Herei...

    Authors: Zhuoxin Guo, Tingting Lu, Lisheng Peng, Huanhuan Cheng, Fuhua Peng, Jin Li, Zhengqi Lu, Shaoqiong Chen and Wei Qiu

    Citation: BMC Neurology 2019 19:156

    Content type: Case report

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  9. Intravenous thrombolysis has been recently introduced in Nepal for the management of acute ischemic stroke. Pre-hospital delay is one of the main reasons that hinder thrombolytic therapy. The objective of this...

    Authors: Gaurav Nepal, Jayant Kumar Yadav, Babin Basnet, Tirtha Man Shrestha, Ghanshyam Kharel and Rajeev Ojha

    Citation: BMC Neurology 2019 19:155

    Content type: Research article

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  11. Multiple Mitochondrial Dysfunctions Syndrome 4 (MMDS4) is manifested as a result of ISCA2 mutations. ISCA2 is a vital component of 4Fe-4S clusters assembly machine. Therefore, in MMDS4 patients, deficient mitocho...

    Authors: Milad Eidi and Masoud Garshasbi

    Citation: BMC Neurology 2019 19:153

    Content type: Case report

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  12. Simultaneous cerebral and myocardial infarction is called cardiocerebral infarction (CCI), and is rarely encountered. Because of the narrow time window and complex pathophysiology, CCI is challenging to immedi...

    Authors: Soichiro Abe, Kanta Tanaka, Hiroshi Yamagami, Kazutaka Sonoda, Hiroya Hayashi, Shuichi Yoneda, Kazunori Toyoda and Masatoshi Koga

    Citation: BMC Neurology 2019 19:152

    Content type: Case report

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  13. This study aimed to investigate the cerebral blood flow (CBF) and frontal lobe cognitive function in severe internal carotid artery (ICA) stenosis patients with different types of collateral circulation.

    Authors: Wei Wei, Xingyang Yi, Jianghai Ruan, Xiaodong Duan, Hua Luo and Zhiyu Lv

    Citation: BMC Neurology 2019 19:151

    Content type: Research article

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  14. Mechanical thrombectomy has been proven as a standard care for moderate to severe ischemic stroke with anterior large vessel occlusion (LVO); however, whether it is equally effective in mild ischemic stroke (M...

    Authors: Xian-Jin Shang, Zhong-Hua Shi, Cai-Feng He, Shuai Zhang, Yong-Jie Bai, Yong-Tao Guo, Bo Sun, Shun Li, Huai-Ming Wang, Zhi-Ming Zhou, Wen-Jie Zi and Xin-Feng Liu

    Citation: BMC Neurology 2019 19:150

    Content type: Research article

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  15. Spinocerebellar ataxia type 3 (SCA3) is the most common subtype among the autosomal dominant cerebellar ataxias, a group of neurodegenerative disorders for which currently no disease-specific therapy is availa...

    Authors: Roderick P. P. W. M. Maas, Ivan Toni, Jonne Doorduin, Thomas Klockgether, Dennis J. L. G. Schutter and Bart P. C. van de Warrenburg

    Citation: BMC Neurology 2019 19:149

    Content type: Study protocol

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  16. Almost 40% of stroke patients have a poor outcome at 3 months after the index event. Predictors for stroke outcome in the early acute phase may help to tailor stroke treatment. Infection and inflammation are c...

    Authors: A. Mengel, L. Ulm, B. Hotter, H. Harms, S. K. Piper, U. Grittner, J. Montaner, C. Meisel, A. Meisel and S. Hoffmann

    Citation: BMC Neurology 2019 19:148

    Content type: Research article

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  17. Triglycerides (TG)/high-density lipoprotein (HDL) cholesterol ratio is a marker of small/dense low-density lipoprotein particles, which are closely associated with various metabolic and vascular diseases. Howe...

    Authors: Ki-Woong Nam, Hyung-Min Kwon, Han-Yeong Jeong, Jin-Ho Park, Hyuktae Kwon and Su-Min Jeong

    Citation: BMC Neurology 2019 19:147

    Content type: Research article

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  18. Familial amyloid polyneuropathy (FAP) or ATTRv (amyloid TTR variant) amyloidosis is a fatal hereditary disease characterized by the deposition of amyloid fibrils composed of transthyretin (TTR). The current di...

    Authors: Estefania P. Azevedo, Anderson B. Guimaraes-Costa, Christianne Bandeira-Melo, Leila Chimelli, Marcia Waddington-Cruz, Elvira M. Saraiva, Fernando L. Palhano and Debora Foguel

    Citation: BMC Neurology 2019 19:146

    Content type: Research article

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  19. Fulminant Guillain-Barré syndrome (GBS) is characterized clinically by rapid progression of severe symptoms, such as the absence of brainstem reflexes, complete tetraplegia and respiratory arrest. The clinical...

    Authors: Yoshitsugu Nakamura, Mikiko Motoki, Takahiko Hirose, Takafumi Hosokawa, Shimon Ishida and Shigeki Arawaka

    Citation: BMC Neurology 2019 19:145

    Content type: Case report

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  20. Vestibular migraine (VM) has been recognized as a diagnostic entity over the past three decades. It affects up to 1% of the general population and 7% of patients seen in dizziness clinics. It is still underdia...

    Authors: Alice A. Takeuti, Mariana L. Fávero, Erica Helena Zaia and Fernando F. Ganança

    Citation: BMC Neurology 2019 19:144

    Content type: Research article

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  21. Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. Patients suffer from a variety of motor and non-motor symptoms that severely affect their daily lives and quality of life. In many...

    Authors: Carolin Siegert, Björn Hauptmann, Nicole Jochems, Andreas Schrader and Ruth Deck

    Citation: BMC Neurology 2019 19:143

    Content type: Study protocol

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    The Correction to this article has been published in BMC Neurology 2019 19:199

  22. Fatigue is one of the most common and debilitating symptoms of multiple sclerosis (MS). The majority of approaches for managing MS fatigue typically require participation in a structured, time-limited program ...

    Authors: Marcia Finlayson, Nadine Akbar, Karen Turpin and Penny Smyth

    Citation: BMC Neurology 2019 19:142

    Content type: Study protocol

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  23. Visual disorders are common in Parkinson’s disease (PD) but their exact frequency and severity are unknown. Good visual functioning is crucial for patients with PD, because of their need to compensate for loss...

    Authors: Carlijn D. J. M. Borm, Mario Werkmann, Femke Visser, Marina Peball, Diana Putz, Klaus Seppi, Werner Poewe, Irene C. Notting, Annemarie Vlaar, Thomas Theelen, Carel Hoyng, Bastiaan R. Bloem and Nienke M. de Vries

    Citation: BMC Neurology 2019 19:141

    Content type: Study protocol

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  24. Body weight supported treadmill training (BWSTT) is a frequently used approach for restoring the ability to walk after spinal cord injury (SCI). However, the duration of BWSTT is usually limited by fatigue of ...

    Authors: Eddy Yu Yeung Cheung, Kevin Ka Ki Yu, Rachel Lai Chu Kwan, Carmen Ka Man Ng, Rosanna Mei Wa Chau and Gladys Lai Ying Cheing

    Citation: BMC Neurology 2019 19:140

    Content type: Research article

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  25. Multiple sclerosis (MS) and stroke are two common causes of death and disability worldwide. The relationship between these two diseases remains unclear. Effective early preventative measures and treatments are...

    Authors: Ye Hong, Huai Rong Tang, Mengmeng Ma, Ning Chen, Xin Xie and Li He

    Citation: BMC Neurology 2019 19:139

    Content type: Research article

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  27. Dystonia is a movement disorder substantially affecting the quality of life and the ability to work. A proportion of patients does not respond to first line pharmacotherapy. Deep brain stimulation (DBS) is est...

    Authors: Rebekka M. Ortiz, Filip Scheperjans and Eero Pekkonen

    Citation: BMC Neurology 2019 19:137

    Content type: Research article

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  28. A short ketogenic diet (KD) treatment can prevent migraine attacks and correct excessive cortical response. Here, we aim to prove if the KD-related changes of cortical excitability are primarily due to cerebra...

    Authors: Cherubino Di Lorenzo, Gianluca Coppola, Martina Bracaglia, Davide Di Lenola, Giulio Sirianni, Paolo Rossi, Giorgio Di Lorenzo, Vincenzo Parisi, Mariano Serrao, Mackenzie C. Cervenka and Francesco Pierelli

    Citation: BMC Neurology 2019 19:136

    Content type: Research article

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  29. Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to investigate fat infiltration and muscle size in trunk muscles...

    Authors: Gro Solbakken, Bård Bjørnarå, Eva Kirkhus, Bac Nguyen, Gunnar Hansen, Jan C. Frich and Kristin Ørstavik

    Citation: BMC Neurology 2019 19:135

    Content type: Research article

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  31. Heat stroke (HS) is a critical illness that can cause multiple organ dysfunction, including damage to the central nervous system (CNS), which can be life-threatening in severe cases. Brain lesions in patients ...

    Authors: Lizhi Cao, Juan Wang, Yaxuan Gao, Yumei Liang, Jinhua Yan, Yunhai Zhang, Mingqin Zhu, Tianfei Luo and Jiafeng Chen

    Citation: BMC Neurology 2019 19:133

    Content type: Case report

    Published on:

  33. Diabetic chorea appears during the course of poorly-controlled diabetes. While chorea associated with diabetes mellitus usually occurs during hyperglycemic episodes, hypoglycemia can also cause diabetic chorea...

    Authors: Eriko Matsushima, Hiroshi Shiota, Kentaro Watanabe, Yuichiro Otsuka, Midori Yamana, Suguru Yamaguchi, Fujiko Egashira, Satoshi Kamei and Hisamitsu Ishihara

    Citation: BMC Neurology 2019 19:131

    Content type: Case report

    Published on:

  34. Interferon (IFN) beta drugs have been approved for the treatment of relapsing forms of multiple sclerosis (RMS) for more than 20 years and are considered to offer a favourable benefit-risk profile. In July 201...

    Authors: Annette Kolb-Mäurer, Cord Sunderkötter, Borries Kukowski and Sven G. Meuth

    Citation: BMC Neurology 2019 19:130

    Content type: Debate

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  35. Multiple sclerosis (MS) is a neurological disease of the central nervous system and is associated with many psychosocial symptoms that are difficult to manage including low mood, anxiety, fatigue and pain, as ...

    Authors: Amy-Lee Sesel, Louise Sharpe, Heidi N. Beadnall, Michael H. Barnett, Marianna Szabo and Sharon L. Naismith

    Citation: BMC Neurology 2019 19:129

    Content type: Study protocol

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  36. Mood disorder after stroke is common but drug and psychosocial treatments have been assessed with disappointing results. Preventing mood disorder from developing in the first place could be a better approach a...

    Authors: Kate Hill, Allan House, Peter Knapp, Carrie Wardhaugh, John Bamford and Andy Vail

    Citation: BMC Neurology 2019 19:128

    Content type: Research article

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  37. Immune cells are involved in all stages of acute ischaemic stroke (AIS) and possess both neuroprotective and neurodamaging properties. It has been suggested that immune system activation after stroke may be as...

    Authors: Neringa Jucevičiūtė, Paulius Mikužis and Renata Balnytė

    Citation: BMC Neurology 2019 19:127

    Content type: Research article

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  38. Autoimmune encephalitis (AE) is a newly recognized autoimmune disorders in which the targets are proteins or receptors involved in synaptic transmission and neuronal excitability. α-amino-3-hydroxy-5-methyl-4-...

    Authors: Qingyang Luo, Xianghong Wu and Wen Huang

    Citation: BMC Neurology 2019 19:126

    Content type: Case report

    Published on:

  39. Non-dystrophic myotonias (NDMs) are skeletal muscle disorders involving myotonia distinct from myotonic dystrophy. It has been reported that the muscle pathology is usually normal or comprises mild myopathic c...

    Authors: Takanori Hata, Takamura Nagasaka, Kishin Koh, Mai Tsuchiya, Yuta Ichinose, Haitian Nan, Kazumasa Shindo and Yoshihisa Takiyama

    Citation: BMC Neurology 2019 19:125

    Content type: Case report

    Published on:

  41. The neurofibromatoses (NF) are a group of genetic disorders that interfere negatively with the quality of life (QoL) and influence physical, emotional and social statuses. Studying the effects of neurofibromat...

    Authors: Akram Sanagoo, Leila Jouybari, Fatemeh Koohi and Fatemeh Sayehmiri

    Citation: BMC Neurology 2019 19:123

    Content type: Research article

    Published on:

  43. No longitudinal, long-term, follow-up studies have explored the association between presence and severity of variations in extracranial venous anatomy, and clinical outcomes in patients with multiple sclerosis...

    Authors: Sirin Gandhi, Karen Marr, Marcello Mancini, Maria Grazia Caprio, Dejan Jakimovski, Avinash Chandra, Jesper Hagemeier, David Hojnacki, Channa Kolb, Bianca Weinstock-Guttman and Robert Zivadinov

    Citation: BMC Neurology 2019 19:121

    Content type: Research article

    Published on:

  44. Clinical diagnosis of Parkinson’s disease (PD) has always lagged behind clinical symptoms. The diagnostic latency might be influenced by many factors. The diagnostic latency of Chinese people with PD has been ...

    Authors: Ying Wan, Yingying Zhu, Yi Luo, Xun Han, Yongsheng Li, Jing Gan, Na Wu, Anmu Xie and Zhenguo Liu

    Citation: BMC Neurology 2019 19:120

    Content type: Research article

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  45. The use of vestibular rehabilitation principles in the management of gaze and postural stability impairments in people with multiple sclerosis (PwMS) has shown promise in pilot work completed in our lab and in...

    Authors: Brian J. Loyd, Annie Fangman, Daniel S. Peterson, Eduard Gappmaier, Michael C. Schubert, Anne Thackery and Lee Dibble

    Citation: BMC Neurology 2019 19:119

    Content type: Study protocol

    Published on:

  46. In patients suffering from Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) disease severity is assessed by Medical Research Counsil (MRC) Scale or Inflammatory Neuropathy Cause and Treatment (INCAT) d...

    Authors: Juliane Klehmet, Svenja Beutner, Sarah Hoffmann, Matthias Dornauer, Friedemann Paul, Ralf Reilmann, Alexander U. Brandt and Andreas Meisel

    Citation: BMC Neurology 2019 19:118

    Content type: Research article

    Published on:

  47. Following spinal cord injury (SCI), family members are often called upon to undertake the caregiving role. This change in the nature of the relationship between the individuals with SCI and their families can ...

    Authors: Gaya Jeyathevan, Jill I. Cameron, B. Catharine Craven, Sarah E. P. Munce and Susan B. Jaglal

    Citation: BMC Neurology 2019 19:117

    Content type: Research article

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  48. STRIVE is a multicenter, observational, open-label, single-arm study of natalizumab in anti–JC virus (JCV) seronegative patients with early relapsing-remitting multiple sclerosis (RRMS). The objective of this ...

    Authors: Jai Perumal, Robert J. Fox, Roumen Balabanov, Laura J. Balcer, Steven Galetta, Shavy Makh, Sourav Santra, Christophe Hotermans and Lily Lee

    Citation: BMC Neurology 2019 19:116

    Content type: Research article

    Published on:

  49. Fabry disease is rare, and the diagnosis is often delayed. Here, we describe a case of Fabry disease resulting in vasculopathy of the central nervous system. Magnetic resonance (MR) black-blood sequence (three...

    Authors: De-Zheng Kong, Ya-Hui Lian, Lin-Jing Wang, Chun-Mei Wang, Yang-Yang Meng and Hong-Wei Zhou

    Citation: BMC Neurology 2019 19:115

    Content type: Case report

    Published on:

  50. Internal jugular vein stenosis (IJVS), characterized by a series of clinical manifestations, such as head and neck symptoms, visual and ear symptoms, as well as sleep disorder, has been receiving attention in ...

    Authors: Min Li, Yuan Sun, Chong Ching Chan, Chunqiu Fan, Xunming Ji and Ran Meng

    Citation: BMC Neurology 2019 19:112

    Content type: Case report

    Published on:

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