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  1. We designed a new multi-modal version of the MSmonitor, called the MSmonitor-Plus and Video calling Care (MPVC), a self-management and education program with e-health interventions that combines frequent use o...

    Authors: M. Hoving, P. J. Jongen, S. M. A. A. Evers, M. A. Edens and E. M. P. E. Zeinstra
    Citation: BMC Neurology 2022 22:423
    Content type: Study protocol Published on:

  2. Meningoencephalocele is a rare malformation caused by congenital and acquired lesions. The association between recurrent bacterial meningitis and meningoencephaloceles with cerebrospinal fluid (CSF) leak is re...

    Authors: Jinru Zhang, Jianchao Wu, Yue Wu, Yaye Wang and Jingzhe Han
    Citation: BMC Neurology 2022 22:421
    Content type: Case report Published on:

  4. Kernohan-Woltman notch phenomenon (KWNP) classically occurs when a lesion causes compression of the contralateral cerebral peduncle against the tentorium, resulting in ipsilateral hemiparesis. It has been stud...

    Authors: Yuliang Lin, Alan Chen-Lung Chou, Xiangming Lin, Zhende Wu, Qichao Ju, Yuexuan Li, Zulong Ye and Bo Zhang
    Citation: BMC Neurology 2022 22:419
    Content type: Case report Published on:

  5. To explore the clinical characteristics and related factors of children with acute disseminated encephalomyelitis (ADEM) with positive anti-myelin oligodendrocyte glycoprotein (MOG) antibody.

    Authors: Jue Shen, Donghui Lin, Tiejia Jiang, Feng Gao and Kewen Jiang
    Citation: BMC Neurology 2022 22:418
    Content type: Research Published on:

  6. Long-onset COVID syndrome has been described in patients with COVID-19 infection with persistence of symptoms or development of sequelae beyond 4 weeks after the onset of acute symptoms, a medium- and long-ter...

    Authors: Alissa Elen Formiga Moura, Danilo Nunes Oliveira, Danielle Mesquista Torres, José Wagner Leonel Tavares-Júnior, Paulo Ribeiro Nóbrega, Pedro Braga-Neto and Manoel Alves Sobreira-Neto
    Citation: BMC Neurology 2022 22:417
    Content type: Research Published on:

  8. The evidence for mechanical thrombectomy in acute basilar artery occlusion has until now remained inconclusive with basilar artery strokes associated with high rates of death and disability. This systematic re...

    Authors: Abid Malik, Brian Drumm, Lucio D’Anna, Isabelle Brooks, Benjamin Low, Oishik Raha, Khawar Shabbir, Orsolya Vittay, Joseph Kwan, Zoe Brown, Omid Halse, Sohaa Jamil, Dheeraj Kalladka, Marius Venter, Harri Jenkins, Neil Rane…
    Citation: BMC Neurology 2022 22:415
    Content type: Research Published on:

    The Correction to this article has been published in BMC Neurology 2022 22:496

  9. Primary Sjögren’s syndrome (pSS) is an autoimmune inflammatory disease characterized by dryness of the eyes, mouth and other mucous membranes. Patients with pSS can also present with extraglandular manifestati...

    Authors: ChenLing Lv, FeiYan Zhu, Chao Chen, YunLing Wang, DengJun Guo and ZhenZhong Zhang
    Citation: BMC Neurology 2022 22:414
    Content type: Case report Published on:

  10. To retrospectively analyze CT and MR imaging features of the brain in patients with hydrogen sulfide poisoning based on clinical symptom grading and to investigate their correlations with clinical symptoms and...

    Authors: Daidi Tang, Ning Tian, Jianming Cai, Jinlin Ma, Tingting Wang, Hongtao Zhang and Fugeng Sheng
    Citation: BMC Neurology 2022 22:413
    Content type: Research Published on:

  11. Seizures can occur unpredictably in patients with acute encephalitis syndrome (AES), and many suffer from poor long-term neurological sequelae. Establishing factors associated with acute seizures risk and poor...

    Authors: Ali M. Alam, Jian P. K. Chen, Greta K. Wood, Bethany Facer, Maneesh Bhojak, Kumar Das, Sylviane Defres, Anthony Marson, Julia Granerod, David Brown, Rhys H. Thomas, Simon S. Keller, Tom Solomon and Benedict D. Michael
    Citation: BMC Neurology 2022 22:412
    Content type: Research Published on:

    The Correction to this article has been published in BMC Neurology 2022 22:451

  12. Primary central nervous system lymphoma (PCNSL) is a rare and aggressive disease. The role of surgical resection in PCNSL has always been the center of debate. Here we investigated the clinical and follow-up d...

    Authors: Xin Cheng, Haoran Chen, Chongran Sun, Buyi Zhang, Jianmin Zhang and Yongjie Wang
    Citation: BMC Neurology 2022 22:411
    Content type: Research Published on:

  15. Mixed data exist regarding the association between hyperglycemia and functional outcome after acute ischemic stroke when accounting for the impact of leptomeningeal collateral flow. We sought to determine whet...

    Authors: Daniel F. Arteaga, Robin Ulep, Kevin K. Kumar, Andrew M. Southerland, Mark R. Conaway, James Faber, Max Wintermark, David Joyner, Vera Sharashidze, Karen Hirsch, Dan-Victor Giurgiutiu, Yousef Hannawi, Yasmin Aziz, Lori Shutter, Anita Visweswaran, Alana Williams…
    Citation: BMC Neurology 2022 22:408
    Content type: Research article Published on:

  17. Variants in the valosin-containing protein (VCP) gene were identified as one of the causes for inclusion body myopathy associated with Paget disease of the bone and frontotemporal dementia (FTD). Previously ident...

    Authors: Ryota Kobayashi, Hiroya Naruse, Shinobu Kawakatsu, Chifumi Iseki, Yuya Suzuki, Shingo Koyama, Daichi Morioka, Hiroyuki Ishiura, Jun Mitsui, Yasuyuki Ohta, Shoji Tsuji, Tatsushi Toda and Koichi Otani
    Citation: BMC Neurology 2022 22:406
    Content type: Case report Published on:

  18. MicroRNAs (miR or miRNA) are short regulatory RNAs, which modulate post-transcriptional gene expression. Dysregulation of these molecules contributes to pathogenicity of autoimmune disorders, such as multiple ...

    Authors: Sepide Ali Ashrafi, Milad Asadi, Dariush Shanehbandi, Saeed Sadigh Eteghad, Asra Fazlollahi, Seyed Aria Nejadghaderi and Sheida Shaafi
    Citation: BMC Neurology 2022 22:405
    Content type: Research Published on:

  19. The anti-SOX-1 antibodies have been mainly associated with Lambert-Eaton Myasthenic Syndrome (LETMS) and Small-Cell Lung Cancer (SCLC). In this report, we describe the interesting case of a patient with serum ...

    Authors: Ennio Polilli, Antonella Frattari, Jessica Elisabetta Esposito, Gilda Angelini, Annalisa Di Risio, Elena Mazzotta, Simona Coladonato, Giancarlo Di Iorio, Giustino Parruti and Pierluigi Tocco
    Citation: BMC Neurology 2022 22:404
    Content type: Case report Published on:

  20. Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) and mild encephalopathy associated with excitotoxicity (MEEX) are the most frequent acute encephalopathies in pediatric patients in...

    Authors: Yuki Nakajima, Shinya Kobayashi, Hideki Tanoue, Sayaka Ishihara, Ayako Kamiya, Nanako Kawata, Mari Asakura, Daichi Suzuki, Natsuko Obana, Kenta Hayashi, Takahiro Kawaguchi, Masahiro Noda, Kunihiro Oba, Tatsuo Katori, Tsutomu Kageyama and Masashi Ogasawara
    Citation: BMC Neurology 2022 22:403
    Content type: Case report Published on:

  21. A frequent post stroke disorder in lateralized attention is visuospatial neglect (VSN). As VSN has a strong negative impact on recovery in general and independence during daily life, optimal treatment is deeme...

    Authors: Marij Middag-van Spanje, Teresa Schuhmann, Tanja Nijboer, Olof van der Werf, Alexander T. Sack and Caroline van Heugten
    Citation: BMC Neurology 2022 22:402
    Content type: Study protocol Published on:

  22. Neuronal intranuclear inclusion disease (NIID) is a progressive neurodegenerative disease. Patients with NIID may present with heterogeneous clinical symptoms, including episodic encephalopathy, dementia, limb...

    Authors: Ning Su, He-Jiao Mao, Chen-Hui Mao, Li-Ying Cui, Yi-Cheng Zhu, Yan Zhou and Jun Ni
    Citation: BMC Neurology 2022 22:401
    Content type: Case report Published on:

  23. Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disease that involves damage to the peripheral nervous system. The course of the disease can progress for more than 8 weeks, with frequ...

    Authors: Yan Jin, Hong Chu, Hongjuan Dong, Hongyang Wang, Qingping Wang, Xiaoquan Zhao, Dongdong Qin, Zuneng Lu and Chao Weng
    Citation: BMC Neurology 2022 22:400
    Content type: Case report Published on:

  24. Undoubtedly, stroke is expanding as a global public health issue. Stroke-related deaths are attributable to modifiable risk factors. A demographic shift in Ethiopia increased the prevalence of stroke risk fact...

    Authors: Hussen Abdu, Fentaw Tadese and Girma Seyoum
    Citation: BMC Neurology 2022 22:399
    Content type: Research Published on:

  25. Dysferlinopathy is an autosomal recessive muscular dystrophy caused by pathogenic variants in the dysferlin (DYSF) gene. This disease shows heterogeneous clinical phenotypes and genetic characteristics.

    Authors: Ning Wang, Xu Han, Shengpu Hao, Jingzhe Han, Xiaomeng Zhou, Shuyan Sun, Jin Tang, Yanpeng Lu, Hongran Wu, Shaojuan Ma, Xueqin Song and Guang Ji
    Citation: BMC Neurology 2022 22:398
    Content type: Research Published on:

  26. Colloid cyst (CC) is a rare and benign cyst found in the third ventricle near the foramen of Monro. Although the role of surgical resection is well established in symptomatic large-sized CC, it remains debatab...

    Authors: Joo-Hwan Lee, Jong-Hwan Hong, Yeong Jin Kim and Kyung-Sub Moon
    Citation: BMC Neurology 2022 22:397
    Content type: Case report Published on:

  27. Neuroleptic malignant syndrome (NMS) is a rare and occasionally fatal undesirable reaction to dopamine antagonists, and its phenotype is diverse owing to causative drugs. Classically, elevation of serum creati...

    Authors: Yuki Kakinuma, Ryota Amano, Atsushi Ishida, Ichizo Nishino and Katsumi Taki
    Citation: BMC Neurology 2022 22:396
    Content type: Case report Published on:

  28. Engaging in leisure activities was suggested to protect older adults from dementia. However, the association between playing a musical instrument and the risk of dementia is not well-established. This study ai...

    Authors: Ahmed Arafa, Masayuki Teramoto, Saori Maeda, Yukie Sakai, Saya Nosaka, Qi Gao, Haruna Kawachi, Rena Kashima, Chisa Matsumoto and Yoshihiro Kokubo
    Citation: BMC Neurology 2022 22:395
    Content type: Research Published on:

  29. Monthly headache frequency directly correlates with personal/societal burden and impacts severity and preventive treatment decisions. This post hoc analysis identified shifts from higher to lower frequency hea...

    Authors: Patricia Pozo-Rosich, David W. Dodick, Anders Ettrup, Joe Hirman and Roger Cady
    Citation: BMC Neurology 2022 22:394
    Content type: Research Published on:

  30. Transverse myelitis (TM) is characterized by acute development of motor, sensory and autonomic dysfunctions due to horizontally diffused inflammation in one or more segments of the spinal cord in the absence o...

    Authors: Juan Esteban Oyarzún, Raúl Caulier-Cisterna, Juan Pablo González-Appelgren, Leticia Gonzalez, Oscar Trujillo, Antonio Eblen-Zajjur and Sergio Uribe
    Citation: BMC Neurology 2022 22:393
    Content type: Case report Published on:

  31. Meningioma is the most common type of primary intracranial tumor with 0.1–1% of all primary meningiomas have been reported to develop into metastases. However, there is no proven therapeutic strategy for multi...

    Authors: Jia-Li Zhao, Jing Liu, Ming Fang, Chen Luo, Zhen-Bang Gu and Long Huang
    Citation: BMC Neurology 2022 22:392
    Content type: Case report Published on:

  32. Calcified amorphous tumor (CAT) of the heart is a rare non-neoplastic intracardiac mass, a calcium deposition surrounded by amorphous fibrous tissue, and possibly causes cerebral embolism. Even rarer is CAT as...

    Authors: Motoya Kimura, Jun-Ichi Niwa, Hideaki Ito, Katsuhiko Matsuyama and Manabu Doyu
    Citation: BMC Neurology 2022 22:391
    Content type: Case report Published on:

  33. The incidence of osteosarcoma as a secondary neoplasm in glioblastoma patient is extremely rare. The genetic characteristic still remains unclear until now.

    Authors: Guo-zhong Yi, Tai-chen Zhu, Tian-shi Que, Zhi-yong Li and Guang-long Huang
    Citation: BMC Neurology 2022 22:390
    Content type: Case report Published on:

  34. Root motor conduction time (RMCT) can noninvasively evaluate the status of the proximal root segment. However, its clinical application remains limited, and wider studies regarding its use are scarce. We aimed...

    Authors: Dougho Park, Sang-Eok Lee, Jae Man Cho, Joong Won Yang, Donghoon Yang, Mansu Kim and Heum Dai Kwon
    Citation: BMC Neurology 2022 22:389
    Content type: Research Published on:

  35. Multiple sclerosis is an inflammatory and neurodegenerative disease. People with multiple sclerosis (pwMS) experience chronic fatigue which is difficult to deal with therapeutically and greatly affects health-...

    Authors: María Dolores Guerrero Aznar, María Dolores Villanueva Guerrero, Jaime Cordero Ramos, Sara Eichau Madueño, María Morales Bravo, Rocío López Ruiz and Margarita Beltrán García
    Citation: BMC Neurology 2022 22:388
    Content type: Review Published on:

  36. Neuro-melioidosis, comprising 4% of all cases of melioidosis carries a risk of high morbidity and mortality. We describe two Sri Lankan patients presenting with long segment myelitis secondary to melioidosis.

    Authors: Sahathevan Vithoosan, Asha Kumarasiri, Nadun Madushanka Vithanage and Bimsara Senanayake
    Citation: BMC Neurology 2022 22:387
    Content type: Case report Published on:

  38. Complex Regional Pain Syndrome (CRPS) is a disabling pain disorder that is most common after a distal limb fracture. While the acute systemic immune response to the injury is thought to play a role in the deve...

    Authors: Luke Parkitny, James H McAuley, Robert D. Herbert, Flavia Di Pietro, Aidan G Cashin, Michael C Ferraro and G. Lorimer Moseley
    Citation: BMC Neurology 2022 22:385
    Content type: Research Published on:

  39. Neurovascular compression (NVC) produces morphological changes on the trigeminal nerve root is considered the cause of trigeminal neuralgia (TN), but there were some patients with TN found no NVC, and also NVC...

    Authors: Tao Sun, Qinghao Huang, Chuangfeng Li, Wensheng Yang, Wentao Wang, Longshuang He, Jinlong Liu and Chao Yang
    Citation: BMC Neurology 2022 22:384
    Content type: Research Published on:

  40. As a natural antioxidant, uric acid plays a protective role against neurodegenerative disorders, including Parkinson’s disease (PD). Therefore, the risk of PD has been found to be lower in people with hyperuri...

    Authors: Asra Fazlollahi, Mahdi Zahmatyar, Hossein Alizadeh, Maryam Noori, Nasrin Jafari, Seyed Aria Nejadghaderi, Mark J. M. Sullman, Koroush Gharagozli, Ali-Asghar Kolahi and Saeid Safiri
    Citation: BMC Neurology 2022 22:383
    Content type: Research Published on:

  41. Magnetic resonance imaging (MRI) plays a crucial role in diagnosing spinal cord infarction (SCI). However, the findings are often indistinguishable from those of other intramedullary diseases, such as neuromye...

    Authors: Makoto Kobayashi
    Citation: BMC Neurology 2022 22:382
    Content type: Research Published on:

  42. Turner syndrome (TS) is a rare condition associated with a completely or partially missing X chromosome that affects 1 in 2500 girls. TS increases the risk of autoimmune diseases, including Graves’ disease (GD...

    Authors: Paulo Ribeiro Nóbrega, Francisco Bruno Santana da Costa, Pedro Gustavo Barros Rodrigues, Thais de Maria Frota Vasconcelos, Danyela Martins Bezerra Soares, Jéssica Silveira Araújo, Daniel Aguiar Dias, Manoel Alves Sobreira-Neto, Anderson Rodrigues Brandão de Paiva, Pedro Braga-Neto, Fernando Kok and Eveline Gadelha Pereira Fontenele
    Citation: BMC Neurology 2022 22:381
    Content type: Case report Published on:

  43. Oculomotor nerve palsy (ONP) may result from posterior communicating artery (PcomA) aneurysms. We aimed to evaluate the resolution of ONP after endovascular treatment with the intention of clarifying predictor...

    Authors: Bin Wang, Sheng Liu, Shi-Jie Na, Ya Peng, Wen-Bin Ding, Lin-Bo Zhao, Zhen-Yu Jia, Hai-Bin Shi and Qing Feng
    Citation: BMC Neurology 2022 22:380
    Content type: Research Published on:

  44. We conducted this study to compare the risk of reinfection between multiple sclerosis (MS) patients and a control group without MS.

    Authors: Mahdi Barzegar, Amirreza Manteghinejad, Sara Bagherieh, Setayesh Sindarreh, Omid Mirmosayyeb, Shaghayegh Haghjooy Javanmard, Vahid Shaygannejad and Maryam Nasirian
    Citation: BMC Neurology 2022 22:379
    Content type: Research Published on:

  45. Acute vestibular syndrome (AVS) is a common clinical syndrome in neurology clinics and emergency department. Canonical standard for AVS diagnosis requires the presence of persistent vertigo for more than 24 h....

    Authors: Tao Qiu, Xiaoyan Dai, Xiaoya Xu, Guiqin Zhang, Linming Huang and Qingping Gong
    Citation: BMC Neurology 2022 22:378
    Content type: Research Published on:

  47. DNA methyltransferase 1 (DNMT1) exerts imperative functions in neuropathic pain (NP). This study explored the action of RNA interference-mediated DNMT1 silencing in NP by regulating microglial M2 polarization.

    Authors: Ying Tan, Zongjiang Wang, Tao Liu, Peng Gao, Shitao Xu and Lei Tan
    Citation: BMC Neurology 2022 22:376
    Content type: Research Published on:

  48. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited arteriopathy typically caused by mutations in the NOTCH-3 gene. Few detailed descriptions of...

    Authors: Liuhua Pan, Yan Chen and Shanshan Zhao
    Citation: BMC Neurology 2022 22:375
    Content type: Case report Published on:

  50. Sexual dysfunction (SD) is a common comorbidity in people with multiple sclerosis (pwMS). It affects the quality of life and remains an overlooked condition. The objective of this study was to describe how Col...

    Authors: Mariana Gaviria- Carrillo, Silvia Juliana Bueno-Florez and Paola Andrea Ortiz-Salas
    Citation: BMC Neurology 2022 22:372
    Content type: Research Published on:
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