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  1. Many peripheral blood biomarkers are associated with glioma grade, but eosinophils (Eo) are scarcely reported. This study assessed preoperative peripheral eosinophil levels and other peripheral biomarkers pres...

    Authors: Zhenxing Huang, Liang Wu, Zonggang Hou, Pengfei Zhang, Gen Li and Jian Xie

    Citation: BMC Neurology 2019 19:313

    Content type: Research article

    Published on:

  2. Vertebral artery dissection (VAD) may cause cerebral ischemia and impair quality of life (QOL) despite of good functional outcome. The aim of this study was the multimodal analysis of patient characteristics a...

    Authors: Rainer J. Strege, Reinhard Kiefer and Manfred Herrmann

    Citation: BMC Neurology 2019 19:312

    Content type: Research article

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  3. Primary central nervous system lymphoma (PCNSL) is a rare, malignant, non-Hodgkin’s lymphoma of the brain, leptomeninges, and rarely the spinal cord. PCNSL has characteristic magnetic resonance imaging (MRI) f...

    Authors: Seung-Ho Jeon, Mi-Kyoung Kang, Seung Jae Lee, Byoung-Soo Shin and Hyun Goo Kang

    Citation: BMC Neurology 2019 19:311

    Content type: Case report

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  5. The mechanisms underlying the online modulation of motor speech in Parkinson’s disease (PD) have not been determined. Moreover, medical and rehabilitation interventions for PD-associated motor speech disorder ...

    Authors: Ying Liu, Yuchang Gui, Jincui Hu, Shanshan Liang, Sixia Mo, Yuanfang Zhou, Yujian Li, Fengkun Zhou and Jianwen Xu

    Citation: BMC Neurology 2019 19:309

    Content type: Research article

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  7. Status epilepticus (SE) is an emergency neurological disorder that affects quality of life and is associated with high mortality risk. Three scores have been developed to predict the risk of in-hospital death, bu...

    Authors: Prapassara Sirikarn, Porjai Pattanittum and Somsak Tiamkao

    Citation: BMC Neurology 2019 19:307

    Content type: Research article

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  8. Treatment with anticoagulants, including direct oral anticoagulants (DOACs), should be considered for patients diagnosed with atrial fibrillation (AF) deemed at risk of ischaemic stroke. There are limited real...

    Authors: Yaqoob Bhat, Anand Dixit, Amit Mistri, Bhavini Patel, Sadat Haider Quoraishi and James Uprichard

    Citation: BMC Neurology 2019 19:306

    Content type: Study protocol

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  9. Progressive Supranuclear Palsy (PSP) is the most frequent form of atypical Parkinsonism. Although there is preliminary evidence for the benefits of gait rehabilitation, balance training and oculomotor exercise...

    Authors: Susan C. Slade, Martin Underwood, Jennifer L. McGinley and Meg E. Morris

    Citation: BMC Neurology 2019 19:305

    Content type: Research article

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  10. Paraneoplastic limbic encephalitis (PLE) is a rare autoimmune neurological syndrome observed in cancer patients. PLE is difficult to diagnose and presents a variable response to treatment, depending on the cha...

    Authors: Raffaele Longo, Marc Wagner, Benjamin Savenkoff, Mathilde Chastenet de Castaing, Guillaume Desiro, Zead Tubail, Laurent Hennequin, Sinan Ben Mahmoud, Nathalie Marcon, Philippe Quetin, Marco Campitiello and Francesca Plastino

    Citation: BMC Neurology 2019 19:304

    Content type: Case report

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  12. Visual field defects caused by injury to Meyer’s loop (ML) are common in patients undergoing anterior temporal lobectomy during epilepsy surgery. Evaluation of the anatomical shapes of the curving, fanning and...

    Authors: Yong-Zhi Shan, Zhen-Ming Wang, Xiao-Tong Fan, Hua-Qiang Zhang, Lian-Kun Ren, Peng-Hu Wei and Guo-Guang Zhao

    Citation: BMC Neurology 2019 19:302

    Content type: Research article

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  13. McLeod syndrome is a rare X-linked recessive acanthocytosis associated with neurological manifestations including progressive chorea, cognitive impairment, psychiatric disturbances, seizures, and sensorimotor ...

    Authors: Takenobu Murakami, Dan Abe, Hideyuki Matsumoto, Ryo Tokimura, Mitsunari Abe, Amanda Tiksnadi, Shunsuke Kobayashi, Chikako Kaneko, Yuka Urata, Masayuki Nakamura, Akira Sano and Yoshikazu Ugawa

    Citation: BMC Neurology 2019 19:301

    Content type: Case report

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  14. The benefit of intravenous thrombolysis (IVT) for acute ischemic stroke is time dependent. Despite great effort, the median door-to-needle time (DNT) was 60 min at the United States stroke centers. We investig...

    Authors: Demi Tran, Zhu Zhu, Mohammad Shafie, Hermelinda Abcede, Dana Stradling and Wengui Yu

    Citation: BMC Neurology 2019 19:300

    Content type: Research article

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  15. Neologisms are commonly encountered in patients with acute cerebrovascular diseases, particularly in those with Wernicke’s aphasia. However, few studies have investigated primary progressive aphasia with neolo...

    Authors: Hiroyuki Watanabe, Manabu Ikeda and Etsuro Mori

    Citation: BMC Neurology 2019 19:299

    Content type: Case report

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  16. Stroke-associated pneumonia (SAP) is a common complication of cerebrovascular disease. The A2DS2 score has been used to predict the risk of SAP. However, hyperglycemia is not included in this scale. The purpose o...

    Authors: Yang Li, Yu Zhang, Liansheng Ma, Xiaoyuan Niu and Junsen Chang

    Citation: BMC Neurology 2019 19:298

    Content type: Research article

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  17. A huge spherical intracranial mass can sometimes be misdiagnosed, due to the lack of typical radiographic features. Thrombosed giant intracranial aneurysms (GIAs) are an uncommon but still a possible different...

    Authors: Mehdi Chihi, Ramazan Jabbarli, Oliver Gembruch, Sarah Teuber-Hanselmann, Marvin Darkwah Oppong, Daniela Pierscianek, Alexander Radbruch, Martin Glas, Mark Stettner and Ulrich Sure

    Citation: BMC Neurology 2019 19:297

    Content type: Case report

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  18. Glioma is the most common primary malignant brain tumor with high mortality and poor prognosis. Our aim was to clarify the correlation between Kinase-anchored protein 6 (AKAP6) gene polymorphisms and glioma susce...

    Authors: Ming Zhang, Yonglin Zhao, Junjie Zhao, Tingqin Huang and Yuan Wu

    Citation: BMC Neurology 2019 19:296

    Content type: Research article

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  20. Transient ischemic attack (TIA) patients are at high risk of recurrent vascular events; timely management can reduce that risk by 70%. The Protocol-guided Rapid Evaluation of Veterans Experiencing New Transien...

    Authors: D. M. Bravata, L. J. Myers, B. Homoya, E. J. Miech, N. A. Rattray, A. J. Perkins, Y. Zhang, J. Ferguson, J. Myers, A. J. Cheatham, L. Murphy, B. Giacherio, M. Kumar, E. Cheng, D. A. Levine, J. J. Sico…

    Citation: BMC Neurology 2019 19:294

    Content type: Study protocol

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  21. Neurological disorders are an economic and public health burden which requires efficient and adequate medical resources. Currently, little is known about the status of the quality of neurological care services...

    Authors: Jun-Fang Zhang, Meng-Yao Qiu, Yu-Lei Zhang, Xi-Xi Wang, Guo-Ping Wang, Yu Geng, Ke-Zhong Zhang, Kan Fang and Yun-Cheng Wu

    Citation: BMC Neurology 2019 19:293

    Content type: Research article

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  22. Antiepileptic drug (AED) induced dyskinesia is an unusual manifestation in the medical field. In the previous case reports describing first generation-AED related involuntary movements, the authors suggested t...

    Authors: Soo Hwan Yim, Yun Ho Choi, Kyoung Heo and Kyoo ho Cho

    Citation: BMC Neurology 2019 19:292

    Content type: Case report

    Published on:

  23. Mutations of cyclooxygenase gene (COX gene) may increase the susceptibility of ischemic stroke. We investigated five variants (rs5788, rs1330344, rs3842788, rs20417, and rs689466) of two COX genes in order to ...

    Authors: Lei Zhao, Jinghuan Fang, Muke Zhou, Jie Zhou, Lihua Yu, Ning Chen and Li He

    Citation: BMC Neurology 2019 19:291

    Content type: Research article

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  24. In this paper, seizure types, and epilepsy syndromes are elucidated as per ILAE (2010) classification. A brief outline of the antiepileptic drug regimens used and the outcome of seizure control in a two -year ...

    Authors: Inaam N. Mohamed, Maha A. Elseed, Somia Mohamed, Ali Alsir, Emtinan K. Hamid, Ilham M. Omer, Sara M. Elsadig, Yasmin M. Gerais, Abdelgadir H. Osman, Aisha M. Bakhiet and Ahlam A. Hamed

    Citation: BMC Neurology 2019 19:290

    Content type: Research article

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  25. Ischemia-reperfusion (I/R)-induced vascular dysfunction is the main factor to acute ischemic stroke. Sirt3 is one of the sirtuin family members, which plays an important role in the development of neurological...

    Authors: Zhenzhen Zhao, Xiaoxiu Zhang, Yuanqiang Dai, Ke Pan, Yu Deng, Yan Meng and Tao Xu

    Citation: BMC Neurology 2019 19:289

    Content type: Research article

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  26. Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of unknown cause involving the brain and accompanied by prominent eosinophilia. Intracardiac thrombosis is a major cardiac com...

    Authors: Kenichiro Hira, Hideki Shimura, Riyu Kamata, Masashi Takanashi, Akane Hashizume, Keiji Takahashi, Mizuho Sugiyama, Hiroshi Izumi, Nobutaka Hattori and Takao Urabe

    Citation: BMC Neurology 2019 19:288

    Content type: Case report

    Published on:

  27. Fingolimod (Gilenya®) is approved for relapsing forms of multiple sclerosis in the USA. Owing to transient heart-rate effects when initiating fingolimod, eligible patients undergo precautionary baseline assess...

    Authors: Brandon Brown, Jamie L. Weiss, Scott Kolodny, Xiangyi Meng, Ian M. Williams and John A. Osborne

    Citation: BMC Neurology 2019 19:287

    Content type: Research article

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  28. Some studies have looked at the age at menarche and risk of Multiple Sclerosis (MS).We aimed to conduct a systematic review and meta-analysis to estimate a pooled odds ratio of developing MS by increasing age ...

    Authors: Amirreza Azimi, Sara Hanaei, Mohammad Ali Sahraian, Mehdi Mohammadifar, Sreeram V. Ramagopalan and Mahsa Ghajarzadeh

    Citation: BMC Neurology 2019 19:286

    Content type: Research article

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  29. Capsular warning syndrome (CWS) is a rare clinical syndrome, which is defined as a recurrent transient lacunar syndrome. The mechanism and clinical management of CWS remain unclear. The aim of the study was to...

    Authors: Lanying He, Ronghua Xu, Jian Wang, Lili Zhang, Lijuan Zhang, Fangfang Zhou and Weiwei Dong

    Citation: BMC Neurology 2019 19:285

    Content type: Research article

    Published on:

  31. As health behavior varies with increasing age, we aimed to examine the potential barriers in calling emergency medical services (EMS) after recognizing a stroke among 40–74- and 75–99-year-old adults.

    Authors: Shengde Li, Li-Ying Cui, Craig Anderson, Chunpeng Gao, Chengdong Yu, Guangliang Shan, Longde Wang and Bin Peng

    Citation: BMC Neurology 2019 19:283

    Content type: Research article

    Published on:

  32. Diagnosing dysphagia in acute stroke patients is crucial, as this comorbidity determines morbidity and mortality; we therefore investigated the impact of flexible nasolaryngeal endoscopy (FEES) in acute stroke...

    Authors: Tobias Braun, Martin Juenemann, Maxime Viard, Marco Meyer, Iris Reuter, Mario Prosiegel, Manfred Kaps and Christian Tanislav

    Citation: BMC Neurology 2019 19:282

    Content type: Research article

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  34. Parkinson’s disease (PD) affects many physiological systems essential for balance control. Recent studies suggest that intensive and cognitively demanding physical exercise programs are capable of inducing pla...

    Authors: Erika Franzén, Hanna Johansson, Malin Freidle, Urban Ekman, Martin Benka Wallén, Ellika Schalling, Alexander Lebedev, Martin Lövdén, Staffan Holmin, Per Svenningsson and Maria Hagströmer

    Citation: BMC Neurology 2019 19:280

    Content type: Study protocol

    Published on:

  35. Cerebral infarction occurs when the arteries to brain are obstructed, and motor impairment contralateral to responsible lesion is commonly recognized. Few studies have profiled the characteristics of cases wit...

    Authors: Zhe-Ren Tan, Chen Zhang and Fa-Fa Tian

    Citation: BMC Neurology 2019 19:279

    Content type: Research article

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  36. Wilson disease (WD) is genetically induced failure of copper metabolism which can be successfully treated with pharmacological agents. The prognosis for survival in most WD patients is favorable if diagnosis a...

    Authors: Wojciech Masełbas, Anna Członkowska, Tomasz Litwin and Maciej Niewada

    Citation: BMC Neurology 2019 19:278

    Content type: Research article

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  37. Early supported discharge (ESD) has been shown to be efficient and safe as part of the stroke care pathway. The best results have been seen with a multidisciplinary team and after mild to moderate stroke. Howe...

    Authors: Lena Rafsten, Anna Danielsson, Asa Nordin, Ann Björkdahl, Asa Lundgren-Nilsson, Maria E. H. Larsson and Katharina S. Sunnerhagen

    Citation: BMC Neurology 2019 19:277

    Content type: Research article

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  38. Internal carotid artery dissection has been well recognized as a major cause of ischaemic stroke in young and middle-aged adults. However, internal carotid artery dissection induced hypoglossal nerve palsy has...

    Authors: Zhaoyao Chen, Jun Yuan, Hui Li, Cuiping Yuan, Kailin Yin, Sen Liang, Pengfei Li and Minghua Wu

    Citation: BMC Neurology 2019 19:276

    Content type: Case report

    Published on:

  39. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex disease, whose exact cause remains unclear. A wide range of risk factors has been proposed that helps understanding potential disease pa...

    Authors: Eliana M. Lacerda, Keith Geraghty, Caroline C. Kingdon, Luigi Palla and Luis Nacul

    Citation: BMC Neurology 2019 19:275

    Content type: Research article

    Published on:

  40. Early prediction of unfavorable outcome after ischemic stroke is of great significance to the clinical and therapeutic management. A nomogram is a better visual tool than earlier models and prognostic scores t...

    Authors: Chao Sun, Xiang Li, Baili Song, Xiangliang Chen, Linda Nyame, Yukai Liu, Dan Tang, Mako Ibrahim, Zheng Zhao, Chao Liu, Miao Yan, Xiding Pan, Jie Yang, Junshan Zhou and Jianjun Zou

    Citation: BMC Neurology 2019 19:274

    Content type: Research article

    Published on:

  41. The incidence of autoimmune encephalitis has risen globally. There are two general categories of disease-associated antibodies that can be tested for: neuronal surface and intracellular. However, testing both ...

    Authors: Abhinbhen W. Saraya, Kanthita Worachotsueptrakun, Kritchai Vutipongsatorn, Chanikarn Sonpee and Thiravat Hemachudha

    Citation: BMC Neurology 2019 19:273

    Content type: Research article

    Published on:

  42. Patients with acute ischemic stroke (AIS) often experience low serum free triiodothyronine (FT3), but the association of low FT3 with stroke severity, subtype and prognosis has not yet been thoroughly studied,...

    Authors: Shanchao Zhang, Xia Zhao, Shan Xu, Jing Yuan, Zhihua Si, Yang Yang, Shan Qiao, Xuxu Xu and Aihua Wang

    Citation: BMC Neurology 2019 19:272

    Content type: Research article

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  44. In the nineteenth century, Jean Martin Charcot explained functional neurological disorder (formerly called conversion disorder) as a “psychodynamic” lesion. Numerous advances in neuroimaging have permitted ide...

    Authors: Silvio Galli, Selma Aybek, Sylvie Chokron, Thierry Moulin and Eloi Magnin

    Citation: BMC Neurology 2019 19:270

    Content type: Case report

    Published on:

  45. To determine whether items of the Chinese version of the Montreal Cognitive Assessment Basic (MoCA-BC) could discriminate among cognitively normal controls (NC), and those with mild cognitive impairment (MCI),...

    Authors: Yan-Rong Zhang, Yun-Long Ding, Ke-liang Chen, Yan Liu, Can Wei, Ting-ting Zhai, Wen-Juan Wang and Wan-Li Dong

    Citation: BMC Neurology 2019 19:269

    Content type: Research article

    Published on:

  46. Secondary central nervous system lymphoma (SCNSL) is defined as secondary central nervous system (CNS) involvement in patients with systemic lymphoma. It is considered a profoundly adverse complication with in...

    Authors: Yuchen Wu, Yaming Wang, Xuefei Sun, Xueyan Bai, Jun Qian, Hong Zhu, Qu Cui, Ruixian Xing, Yuedan Chen, Qing Liu, Jiayuan Guo, Nan Ji, Shengjun Sun and Yuanbo Liu

    Citation: BMC Neurology 2019 19:268

    Content type: Research article

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  47. To study the association of caregiver factors and stroke patient factors with rehospitalizations over the first 3 months and subsequent 3–12 months post-stroke in Singapore.

    Authors: Shilpa Tyagi, Gerald C. H. Koh, Nan Luo, Kelvin B. Tan, Helen Hoenig, David B. Matchar, Joanne Yoong, Angelique Chan, Kim En Lee, N. Venketasubramanian, Edward Menon, Kin Ming Chan, Deidre Anne De Silva, Philip Yap, Boon Yeow Tan, Effie Chew…

    Citation: BMC Neurology 2019 19:267

    Content type: Research article

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  48. Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory disorder in the central nervous system (CNS) with distinct clinical, radiological, an...

    Authors: Xiao-hang Liu, Fan Jin, Meng Zhang, Mei-xi Liu, Tao Wang, Bo-ju Pan and Lu Zhang

    Citation: BMC Neurology 2019 19:266

    Content type: Case report

    Published on:

  49. Intravenous thrombolysis (IVT) plays a prominent role in the treatment of acute ischemic stroke (AIS). The sooner IVT is administered, the higher the odds of a good outcome. Therefore, registering the in-hospi...

    Authors: Laurien S. Kuhrij, Perla J. Marang-van de Mheen, Renske M. van den Berg-Vos, Frank-Erik de Leeuw and Paul J. Nederkoorn

    Citation: BMC Neurology 2019 19:265

    Content type: Research article

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  50. As investigations of disease modifying drugs aim to slow down progression of Alzheimer’ disease (AD) biomarkers to reliably track disease progression gain more importance. This is especially important as clini...

    Authors: Marion Ortner, René Drost, Dennis Heddderich, Oliver Goldhardt, Felix Müller-Sarnowski, Janine Diehl-Schmid, Hans Förstl, Igor Yakushev and Timo Grimmer

    Citation: BMC Neurology 2019 19:264

    Content type: Research article

    Published on:

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