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  1. Content type: Research article

    Stroke is a serious cardiovascular disease and is also the leading cause of long-term disability in developing and developed countries. Because matrix metalloproteinase-9 (MMP-9) is associated with the risk of ma...

    Authors: Ning Gao, Tie Guo, Han Luo, Guolong Tu, Fanglin Niu, Mengdan Yan and Ying Xia

    Citation: BMC Neurology 2019 19:67

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  2. Content type: Research article

    Gait Initiation (GI) is a functional task that challenges the balance control requiring weight shift and a transition from standing to walking. Individuals with Down Syndrome (DS) walk with low velocity, prolo...

    Authors: Carolina Corsi, Veronica Cimolin, Paolo Capodaglio, Claudia Condoluci and Manuela Galli

    Citation: BMC Neurology 2019 19:66

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  3. Content type: Research article

    Embolectomy is the standard of care in acute ischemic stroke (AIS) caused by large vessel occlusion (LVO). Aim of this study was to compare two techniques: A Direct Aspiration First Pass Technique (ADAPT) and ...

    Authors: Alex Brehm, Volker Maus, Ioannis Tsogkas, Ruben Colla, Amélie Carolina Hesse, Roland Gerard Gera and Marios-Nikos Psychogios

    Citation: BMC Neurology 2019 19:65

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  4. Content type: Research article

    To evaluate whether a shorter time of lying supine without a pillow and fasting for solids and liquids (LSFSL) after a lumbar puncture (LP) is associated with a higher risk of post-lumbar puncture headache (PL...

    Authors: Bing Hu, Tian-ming Chen, Bing Liu, Wei Chi, Yi-qing Miao, Xiao-lu Nie, Xiao-xia Peng and Gang Liu

    Citation: BMC Neurology 2019 19:64

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  5. Content type: Research article

    The effect of the blood urea nitrogen (BUN) to creatinine (Cr) ratio (henceforth BUN/Cr) on haemorrhagic transformation (HT) of acute ischaemic stroke (AIS) patients is unclear.

    Authors: Linghui Deng, Shi Qiu, Changyi Wang, Haiyang Bian, Lu Wang, Yuxiao Li, Bo Wu and Ming Liu

    Citation: BMC Neurology 2019 19:63

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  6. Content type: Research article

    Trigeminal neuralgia (TN) is characterized by facial pain that may be sudden, intense, and recurrent. Neurosurgical interventions, such as radiofrequency rhizotomy, can relieve TN pain, but their mechanisms an...

    Authors: Shu-Tian Chen, Jen-Tsung Yang, Hsu-Huei Weng, Hsueh-Lin Wang, Mei-Yu Yeh and Yuan-Hsiung Tsai

    Citation: BMC Neurology 2019 19:62

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  7. Content type: Study protocol

    Aging is often associated with behavioral impairments, but some people age more gracefully than others. Why? One factor that may play a role is individual differences in the distinctiveness of neural represent...

    Authors: Holly Gagnon, Molly Simmonite, Kaitlin Cassady, Jordan Chamberlain, Erin Freiburger, Poortata Lalwani, Shannon Kelley, Bradley Foerster, Denise C. Park, Myria Petrou, Rachael D. Seidler, Stephan F. Taylor, Daniel H. Weissman and Thad A. Polk

    Citation: BMC Neurology 2019 19:61

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  8. Content type: Research article

    Primary familial brain calcification is a rare autosomal dominant or recessive neurodegenerative disease, characterized by bilateral brain calcifications in different areas of the brain. It is a clinically het...

    Authors: Stine Westergaard Mathorne, Kristina Sørensen, Christina Fagerberg, Matthias Bode and Jens Michael Hertz

    Citation: BMC Neurology 2019 19:60

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  9. Content type: Case report

    Scattered extracellular deposits of amyloid within the brain parenchyma can be found in a heterogeneous group of diseases. Its condensed accumulation in the white matter without evidence for systemic amyloidos...

    Authors: Mario Löhr, Almuth F. Kessler, Camelia-Maria Monoranu, Jens Grosche, Thomas Linsenmann, Ralf-Ingo Ernestus and Wolfgang Härtig

    Citation: BMC Neurology 2019 19:59

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  10. Content type: Case report

    Area postrema syndrome (APS) is considered to be one of the most specific clinical presentations of neuromyelitis optica spectrum disorders (NMOSDs). In sub-Saharan Africa, NMOSDs and even more so those reveal...

    Authors: Kossivi Apetse, Josué Euberma Diatewa, Jean Joel Dongmo Tajeuna, Yaovi Mawuéna Dansou, Rolph Bakoudissa, Kokouvi Panabalo Waklatsi, Damelan Kombate, Komi Assogba and Agnon A. Koffi Balogou

    Citation: BMC Neurology 2019 19:58

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  11. Content type: Research article

    Traumatic Brain Injury (TBI) is the most common cause of injury-related death and disability globally, and a common sequelae is cognitive impairment. Addressing post-TBI cognitive deficits is crucial because t...

    Authors: Joao Ricardo Nickenig Vissoci, Leonardo Pestillo de Oliveira, Temitope Gafaar, Michael M. Haglund, Mark Mvungi, Blandina Theophil Mmbaga and Catherine A. Staton

    Citation: BMC Neurology 2019 19:57

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  12. Content type: Research article

    Dopaminergic neuronal loss begins years before motor symptoms appear in Parkinson disease (PD). Thus, reliable biomarkers for early diagnosis and prognosis of PD are an essential pre-requisite to develop disea...

    Authors: Dilini Rathnayake, Thashi Chang and Preethi Udagama

    Citation: BMC Neurology 2019 19:56

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  13. Content type: Research article

    Serum triiodothyronine (T3) concentration was reported to be associated with the prognosis after acute ischemic stroke. The aim of this study was to evaluate the effect of age on the prognostic value of thyroi...

    Authors: Lei-Qing Li, Xiao-Yan Xu, Wen-Yu Li, Xing-Yue Hu and Wen Lv

    Citation: BMC Neurology 2019 19:54

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  14. Content type: Research article

    In persons with migraine, severity of migraine is an important determinant of several health outcomes (e.g., patient quality of life and health care resource utilization). This study investigated how migraine ...

    Authors: Tolulope T. Sajobi, Farnaz Amoozegar, Meng Wang, Natalie Wiebe, Kirsten M. Fiest, Scott B. Patten and Nathalie Jette

    Citation: BMC Neurology 2019 19:53

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  15. Content type: Case report

    Parenchymal neurocysticercosis is a frequent cause of seizures in areas endemic for Taenia solium. At present there is scarce data on the evolution of the levels of circulating metacestodal antigen before, during...

    Authors: Richar Rodríguez-Hidalgo, Arturo Carpio, Erwin Van den Enden and Washington Benítez-Ortiz

    Citation: BMC Neurology 2019 19:52

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  16. Content type: Case report

    Carotid rete mirabile (RM) is a meshwork of multiple, freely intercommunicating arterioles that reconstitute the absent or hypoplastic segments of the internal carotid artery (ICA). Carotid RM has been reporte...

    Authors: Hao Chen, Kun Hou, Xin Wang, Kan Xu and Jinlu Yu

    Citation: BMC Neurology 2019 19:51

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  17. Content type: Research article

    There are currently no standard diagnostic criteria for characterizing advanced Parkinson’s disease (APD) in clinical practice, a critical component in determining ongoing clinical care and therapeutic strateg...

    Authors: Alfonso Fasano, Victor S. C. Fung, Leonardo Lopiano, Bulent Elibol, Irina G. Smolentseva, Klaus Seppi, Annamária Takáts, Koray Onuk, Juan Carlos Parra, Lars Bergmann, Kavita Sail, Yash Jalundhwala and Zvezdan Pirtosek

    Citation: BMC Neurology 2019 19:50

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  18. Content type: Research article

    The prevalence of Restless legs syndrome (RLS) in End Stage Renal Disease (ESRD) patients is higher than that in the general population. However, the associations of RLS within the ESRD population are inconsis...

    Authors: Xiao-Wei Lin, Jun-Fang Zhang, Meng-Yao Qiu, Ling-Yan Ni, Hong-Lei Yu, Sheng-Han Kuo, William G. Ondo, Qing Yu and Yun-Cheng Wu

    Citation: BMC Neurology 2019 19:47

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  19. Content type: Case report

    Contrast-induced encephalopathy (CIE) is a well-known complication of iodinated contrast agents during angiography and vascular interventions. It can manifest as hemiparesis, cortical blindness, speech changes...

    Authors: Wei Zhao, Jinping Zhang, Yun Song, Lili Sun, Meimei Zheng, Hao Yin, Jun Zhang, Wei Wang and Ju Han

    Citation: BMC Neurology 2019 19:46

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  20. Content type: Research article

    The genetic risk factors for carotid stenosis are not fully understood. The aim of this study is to investigate the relationship between variants in platelet activation-relevant genes and carotid stenosis in p...

    Authors: Xingyang Yi, Jing Lin, Qiang Zhou, Ruyue Huang and Zhenxiao Chai

    Citation: BMC Neurology 2019 19:44

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  21. Content type: Case report

    Dural arteriovenous fistula (DAVF) is an uncommon subtype among the intracranial arteriovenous malformations, which is characterized by pathological anastomoses between meningeal arteries and dural venous sinu...

    Authors: Guichen Li, Yang Zhang, Jinchuan Zhao, Xiaobo Zhu, Jinlu Yu and Kun Hou

    Citation: BMC Neurology 2019 19:43

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  22. Content type: Research article

    We aimed to produce a detailed neuropathological analysis of pyramidal motor system pathology and provide its clinical pathological correlation in cases with definite progressive supranuclear palsy (PSP).

    Authors: Zuzana Stejskalova, Zdenek Rohan, Robert Rusina, Adam Tesar, Jaromir Kukal, Gabor G. Kovacs, Ales Bartos and Radoslav Matej

    Citation: BMC Neurology 2019 19:42

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  23. Content type: Research article

    The efficacy of early supported discharge (ESD) has not been tested in current stroke care setting, which provide relatively short hospital stays, access to hyper-acute therapies and early carotid stenosis int...

    Authors: Anna Bråndal, Marie Eriksson, Eva-Lotta Glader and Per Wester

    Citation: BMC Neurology 2019 19:40

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  24. Content type: Study protocol

    After discharge from hospital following a stroke, prescriptions of community-based rehabilitation are often downgraded to “maintenance” rehabilitation or discontinued. This classic therapeutic behavior stems f...

    Authors: Jean-Michel Gracies, Maud Pradines, Mouna Ghédira, Catherine-Marie Loche, Valentina Mardale, Catherine Hennegrave, Caroline Gault-Colas, Etienne Audureau, Emilie Hutin, Marjolaine Baude and Nicolas Bayle

    Citation: BMC Neurology 2019 19:39

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  25. Content type: Study protocol

    Studies have shown positive effects of therapeutic exercise on motor- and cognitive function as well as on psychosocial outcomes in persons with multiple sclerosis (MS). A reduction of inflammatory stress thro...

    Authors: Niklas Joisten, Annette Rademacher, Wilhelm Bloch, Alexander Schenk, Max Oberste, Ulrik Dalgas, Dawn Langdon, Daniel Caminada, Mette-Triin Purde, Roman Gonzenbach, Jan Kool, Philipp Zimmer and Jens Bansi

    Citation: BMC Neurology 2019 19:37

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  26. Content type: Research article

    Neuromyelitis optica (NMO) is a severe inflammatory autoimmune disorder of the central nervous system and often results in paralysis or blindness. Rituximab (RTX) is a mouse–human chimeric monoclonal antibody ...

    Authors: Fulin Gao, Bingyan Chai, Cheng Gu, Ruipeng Wu, Tong Dong, Yuping Yao and Yi Zhang

    Citation: BMC Neurology 2019 19:36

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  27. Content type: Study protocol

    Nodding syndrome is a poorly understood neurological disorder of unknown aetiology, affecting several thousand children in Africa. There has been a consistent epidemiological association with infection by the ...

    Authors: Richard Idro, Ronald Anguzu, Rodney Ogwang, Pamela Akun, Catherine Abbo, Amos Deogratius Mwaka, Bernard Opar, Phyellister Nakamya, Mark Taylor, Alison Elliott, Angela Vincent, Charles Newton and Kevin Marsh

    Citation: BMC Neurology 2019 19:35

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  28. Content type: Case report

    Moyamoya vasculopathy (MMV) associated with Graves’ disease (GD) is a rare condition resulting in ischemic stroke accompanied by thyrotoxicity. Radiological findings of vasculitis have been reported in the wal...

    Authors: Hiroto Ito, Syunsuke Yokoi, Kinya Yokoyama, Takumi Asai, Kenji Uda, Yoshio Araki, Syuntaro Takasu, Rei Kobayashi, Hisashi Okada and Satoshi Okuda

    Citation: BMC Neurology 2019 19:34

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  29. Content type: Research article

    Although patients with dementia frequently experience neuropsychological symptoms (NPS) such as agitation, which profoundly impacts patients, caregivers, and the healthcare system, few studies have evaluated t...

    Authors: Myrlene Sanon Aigbogun, Robert Stellhorn, Ann Hartry, Ross A. Baker and Howard Fillit

    Citation: BMC Neurology 2019 19:33

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  30. Content type: Case report

    Collagen VI-related myopathies are a spectrum of muscular diseases with features of muscle weakness and atrophy, multiple contractures of joints, distal hyperextensibility, severe respiratory dysfunction and c...

    Authors: Mengxin Bao, Fei Mao, Zhangning Zhao, Gaoting Ma, Guangjun Xu, Wenjuan Xu, Huan Chen and Meijia Zhu

    Citation: BMC Neurology 2019 19:32

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  31. Content type: Research article

    Ischemic stroke is a leading cause of mortality and morbidity worldwide. Stenosis or blockage of an artery from atherosclerosis can cause insufficient cerebral blood supply, which leads to ischemic stroke. It ...

    Authors: Yan Jiang, Xiaomin Liu, Yifeng Du and Shengnian Zhou

    Citation: BMC Neurology 2019 19:31

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  32. Content type: Research article

    Posterior reversible encephalopathy syndrome (PRES) is a complication that occurs during various diseases’ treatment. Imaging examination is the gold standard for diagnosis. PRES frequently occurrence in patie...

    Authors: Li-Ping Zou, Li-Ying Liu, Hui Li, Yang-Yang Wang, Ying Liu, Jing Chen, Lin-Yan Hu, Meng-Jia Liu, Meng-Na Zhang, Qian Lu and Shu-Fang Ma

    Citation: BMC Neurology 2019 19:30

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  33. Content type: Research article

    Individuals with epilepsy who cannot be adequately controlled with anti-epileptic drugs, refractory epilepsy, may be suitable for surgical treatment following detailed assessment. This is a complex process and...

    Authors: Virginia Mumford, Frances Rapport, Patti Shih, Rebecca Mitchell, Andrew Bleasel, Armin Nikpour, Geoffrey Herkes, Amy MacRae, Melissa Bartley, Sanjyot Vagholkar and Jeffrey Braithwaite

    Citation: BMC Neurology 2019 19:29

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  34. Content type: Case report

    Periodic alternating ping-pong gaze (PPG) is a rare disease with few reports. To our knowledge, there was no report on anti GQ1b antibody syndrome accompanied by PPG. This paper reported a case of anti GQ1b an...

    Authors: Jingzhe Han, Yanan Xie, Haiyan Yan, Yuecheng Cao, HongmeiWang and Duanhua Cao

    Citation: BMC Neurology 2019 19:28

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  35. Content type: Research article

    Autism prevalence continues to grow, yet a universally agreed upon etiology is lacking despite manifold evidence of abnormalities especially in terms of genetics and epigenetics. The authors postulate that the...

    Authors: Frank H. Duffy and Heidelise Als

    Citation: BMC Neurology 2019 19:27

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  36. Content type: Case report

    Mixed cerebrovascular disease is a diagnostic entity that presents with hemorrhagic and ischemic stroke clinically and/or subclinically. Here, we report a patient with mixed vascular risk factors, who presente...

    Authors: Dian He, YunLi Yu, Shan Wu, ShuFen Tian, Hui Yu, Shu Xu and Lan Chu

    Citation: BMC Neurology 2019 19:26

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  37. Content type: Research article

    Atrial fibrillation (AF) is present in 15–20% of patients with acute ischemic stroke. Oral anticoagulation reduces the risk of AF-related recurrent stroke but clinical guideline recommendations are rather vagu...

    Authors: Alexander Wutzler, Christos Krogias, Anna Grau, Roland Veltkamp, Peter U. Heuschmann and Karl Georg Haeusler

    Citation: BMC Neurology 2019 19:25

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  38. Content type: Study protocol

    Malnutrition is one of the crucial factors associated with poor prognosis in critical ill patients, yet a significant evidence gap surrounds the management of initial enteral feeding in severe stroke. The Opti...

    Authors: Fang Yuan, Fang Yang, Wei Zhang, Yi Jia, Yaling Ma, Yongcai Qu, Xinglai Wang, Kang Huo, Chengkai Wang, Xiangjun Yuan, Chaohui Song, Bei Zhang and Wen Jiang

    Citation: BMC Neurology 2019 19:24

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  39. Content type: Research article

    Serum hematological indices such as the neutrophil-lymphocyte ratio (NLR) or monocyte-lymphocyte ratio (MLR) have been used as biomarkers of pathogenic inflammation and prognostication in multiple areas of med...

    Authors: Christopher C. Hemond, Bonnie I. Glanz, Rohit Bakshi, Tanuja Chitnis and Brian C. Healy

    Citation: BMC Neurology 2019 19:23

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  40. Content type: Research article

    Endothelial progenitor cells (EPCs) play an important role in ischemic stroke. However, there are few studies on the relationship between EPC and nondisabling ischemic cerebrovascular events. Our aim was to in...

    Authors: Wang Zhao, Libo Zhao, Juan Liao, Yong Luo and Lanying He

    Citation: BMC Neurology 2019 19:22

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  41. Content type: Research article

    Fatigability has emerged as an important dimension of physical impairment in patients with Spinal Muscular Atrophy (SMA). At present reliable and valid outcome measures for both mildly and severely affected pa...

    Authors: Bart Bartels, Laura E. Habets, Marloes Stam, Renske I. Wadman, Camiel A. Wijngaarde, Marja A. G. C. Schoenmakers, Tim Takken, Erik H.J. Hulzebos, W. Ludo van der Pol and Janke F. de Groot

    Citation: BMC Neurology 2019 19:21

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  42. Content type: Study protocol

    Currently there are no disease-modifying treatments for Parkinson’s disease dementia (PDD), a condition linked to aggregation of the protein α-synuclein in subcortical and cortical brain areas. One of the lead...

    Authors: C. R. A. Silveira, J. MacKinley, K. Coleman, Z. Li, E. Finger, R. Bartha, S. A. Morrow, J. Wells, M. Borrie, R. G. Tirona, C. A. Rupar, G. Zou, R. A. Hegele, D. Mahuran, P. MacDonald, M. E. Jenkins…

    Citation: BMC Neurology 2019 19:20

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  43. Content type: Case report

    Anti leucine-rich glioma inactivated 1 (LGI1) encephalitis is a rare autoimmune encephalitis (AE), characterized by acute or subacute cognitive impairment, faciobrachial dystonic seizures, psychiatric disturba...

    Authors: Xuanting Li, Junliang Yuan, Lei Liu and Wenli Hu

    Citation: BMC Neurology 2019 19:19

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  44. Content type: Research article

    Traumatic brain injuries in Uganda are on the increase, however little is known about the neuropsychological outcomes in survivors. This study characterized patients with traumatic brain injury (TBI) and the a...

    Authors: Paul Bangirana, Bruno Giordani, Olive Kobusingye, Letisia Murungyi, Charles Mock, Chandy C. John and Richard Idro

    Citation: BMC Neurology 2019 19:18

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