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  1. Content type: Research article

    Neuropathic pain is defined as pain caused by a lesion or disease of the somatosensory nervous system and is a major therapeutic challenge. Several screening tools have been developed to help physicians detect...

    Authors: Hans Timmerman, André P. Wolff, Ewald M. Bronkhorst, Oliver H. G. Wilder-Smith, Marcel J. Schenkels, Nick T. van Dasselaar, Frank J. P. M. Huygen, Monique A. H. Steegers and Kris C. P. Vissers

    Citation: BMC Neurology 2018 18:91

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  2. Content type: Research article

    Frontotemporal dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS) are incurable, progressive and fatal neurodegenerative diseases with patients variably affected clinically by motor, behavior, and cognitiv...

    Authors: Vivek Majumder, Jenna M. Gregory, Marcelo A. Barria, Alison Green and Suvankar Pal

    Citation: BMC Neurology 2018 18:90

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  3. Content type: Research article

    Brain autoimmunity has been reported in patients with preceding infection of the central nervous system by herpesviridae. It has been hypothesized that neuronal damage releasing antigens might trigger secondary i...

    Authors: Harald Hegen, Raimund Helbok, Mario Kofler, Bettina Pfausler, Alois Schiefecker, Erich Schmutzhard and Ronny Beer

    Citation: BMC Neurology 2018 18:89

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  4. Content type: Research article

    Sleep disturbances are common in patients with advanced Parkinson disease (PD). The aim of this study was to evaluate a possible association of cortical thickness, cortical and subcortical volume with sleep di...

    Authors: Andrius Radziunas, Vytenis Pranas Deltuva, Arimantas Tamasauskas, Rymante Gleizniene, Aiste Pranckeviciene, Kestutis Petrikonis and Adomas Bunevicius

    Citation: BMC Neurology 2018 18:88

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  5. Content type: Research article

    Young ischemic stroke patients are common while classification and analysis based upon imaging characteristics are rarely reported. We intend to compare the clinical and MRI characteristics of cerebral stroke ...

    Authors: Zhang-Ning Zhao, Xiao-Lin Li, Jin-Zhi Liu, Zhi-Ming Jiang and Ai-Hua Wang

    Citation: BMC Neurology 2018 18:87

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  6. Content type: Research article

    Multiple sclerosis (MS) is the most common non-traumatic condition that leads to disability among young individuals. It is associated with demyelination, inflammation, and neurodegeneration within the central ...

    Authors: Osama Al Wutayd, Ashri Gad Mohamed, Jameelah Saeedi, Hessa Al Otaibi and Mohammed Al Jumah

    Citation: BMC Neurology 2018 18:86

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  8. Content type: Correction

    Following publication of the original article [1], Andrés Damián Ortega Heredia requested that his name be corrected from

    Authors: Germaine Eleanor Torres Herrán, Andrés Damián Ortega Heredia, Braulio Martinez Burbano, Marcos Serrano-Dueñas, María Angélica Ortiz Yepez, Raúl Alberto Barrera Madera, Luis Alfredo Masabanda Campaña, Guillermo David Baño Jiménez, Denny Maritza Santos Saltos and Edgar Patricio Correa Díaz

    Citation: BMC Neurology 2018 18:84

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    The original article was published in BMC Neurology 2018 18:55

  9. Content type: Research article

    The plaques at the dorsal or lateral wall of basilar artery (BA) are associated with pontine infarcts. We sought to explore the correlations between vertebrobasilar artery geometry and BA plaque locations.

    Authors: Jin Yu, Shu Zhang, Ming-Li Li, Yi Ma, Yu-Ru Dong, Min Lou, Feng Feng, Shan Gao, Shi-Wen Wu and Wei-Hai Xu

    Citation: BMC Neurology 2018 18:83

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  10. Content type: Research article

    The treatment of cognitive deficits is challenging in pediatric onset multiple sclerosis (POMS) and in patients with attention deficit hyperactivity disorder (ADHD). We performed a pilot double-blind RCT to ev...

    Authors: Marta Simone, Rosa Gemma Viterbo, Lucia Margari and Pietro Iaffaldano

    Citation: BMC Neurology 2018 18:82

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  11. Content type: Research article

    Worldwide, over 10 million individuals suffer from drug-resistant epilepsy. New therapeutic strategies are needed to address this debilitating disease. Inhibition of sodium-glucose linked transporters (SGLTs),...

    Authors: Mumin Alper Erdogan, Dimas Yusuf, Joanna Christy, Volkan Solmaz, Arife Erdogan, Emin Taskiran and Oytun Erbas

    Citation: BMC Neurology 2018 18:81

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  13. Content type: Case report

    Filamin C-related myofibrillar myopathies (MFM) are progressive skeletal myopathies with an autosomal dominant inheritance pattern. The conditions are caused by mutations of the filamin C gene (FLNC) located in t...

    Authors: Jing Miao, Fei-fei Su, Xue-mei Liu, Xiao-jing Wei, Yun Yuan and Xue-fan Yu

    Citation: BMC Neurology 2018 18:79

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  14. Content type: Research article

    There is uncertainty regarding the effect of anemia and red blood cell transfusion on functional outcome following acute ischemic stroke. We studied the relationship of hemoglobin parameters and red cell trans...

    Authors: Kartavya Sharma, Daniel J. Johnson, Brenda Johnson, Steven M. Frank and Robert D. Stevens

    Citation: BMC Neurology 2018 18:78

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  15. Content type: Case report

    Sarcoidosis is a multi-organ disease of unknown etiology characterised by the presence of epithelioid granulomas, without caseous necrosis. Systemic sarcoidosis is rare among children, while neurosarcoidosis i...

    Authors: Katsunori Shijo, Nobuhiro Moro, Mari Sasano, Mitsuru Watanabe, Hiroshi Yagasaki, Shori Takahashi, Taku Homma and Atsuo Yoshino

    Citation: BMC Neurology 2018 18:77

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  16. Content type: Case report

    Dyke-Davidoff-Masson syndrome is a rare condition of unknown frequency resulting from brain injury due to a multitude of causes; especially in early life. Characteristics include cerebral hemiatrophy/hypoplasi...

    Authors: Anna Misyail Abdul Rashid and Mohamad Syafeeq Faeez Md Noh

    Citation: BMC Neurology 2018 18:76

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  17. Content type: Case report

    Horizontal gaze palsy with progressive scoliosis (HGPPS) is a rare autosomal recessive congenital anomaly characterized by horizontal gaze limitation and progressive scoliosis. We investigated the underlying p...

    Authors: Chi-Wei Lin, Chung-Ping Lo and Min-Chien Tu

    Citation: BMC Neurology 2018 18:75

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  18. Content type: Case report

    Cervical artery dissection is one of the most important causes of ischemic stroke in young age patients. However, multiple cervical artery dissection simultaneously involving the anterior and posterior circula...

    Authors: Sung eun Chung, Tae Hwan Yoon, Kyung Mi Lee, Hyug-Gi Kim and Bum Joon Kim

    Citation: BMC Neurology 2018 18:74

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  19. Content type: Research article

    The respiratory dysfunction of patients with Parkinson’s disease (PD) has drawn increasing attention. This study evaluated the relationship between gray matter volume (GMV), as determined by voxel-based morpho...

    Authors: Sieh-Yang Lee, Meng-Hsiang Chen, Pi-Ling Chiang, Hsiu-Ling Chen, Kun-Hsien Chou, Yueh-Cheng Chen, Chiun-Chieh Yu, Nai-Wen Tsai, Shau-Hsuan Li, Cheng-Hsien Lu and Wei-Che Lin

    Citation: BMC Neurology 2018 18:73

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  20. Content type: Case report

    Guillain-Barré syndrome (GBS), Miller Fisher syndrome (MFS) and Bickerstaff brainstem encephalitis (BBE) are a group of autoimmune neurological disorders (GBS spectrum disorder) that rarely recur. Recently, an...

    Authors: Hiroto Ito, Yuki Hatanaka, Yuki Fukami, Yumiko Harada, Rei Kobayashi, Hisashi Okada, Ayumi Uchibori, Atsuro Chiba and Satoshi Okuda

    Citation: BMC Neurology 2018 18:72

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  21. Content type: Case report

    Hopkins syndrome (HS) is a rare disorder presenting with acute flaccid paralysis of the limbs following an asthma attack. Neurologists encounter a diagnostic challenge if patients without a history of bronchia...

    Authors: Fumie Hayashi, Shintaro Hayashi, Dai Matsuse, Ryo Yamasaki, Keiji Yonekura and Jun-ichi Kira

    Citation: BMC Neurology 2018 18:71

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  23. Content type: Study protocol

    Differentiation of Parkinson’s disease (PD) from the various types of atypical parkinsonism (AP) such as multiple system atrophy (MSA), progressive supranuclear palsy (PSP), dementia with Lewy bodies (DLB), co...

    Authors: Anouke van Rumund, Marjolein B. Aerts, Rianne A. J. Esselink, Frederick J. A. Meijer, Marcel M. Verbeek and Bastiaan R. Bloem

    Citation: BMC Neurology 2018 18:69

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  24. Content type: Research article

    On-treatment magnetic resonance imaging lesions may predict long-term clinical outcomes in patients receiving interferon β-1a. This study aimed to assess the effect of active T2 and T1 gadolinium-enhancing (Gd...

    Authors: Anthony Traboulsee, David K. B. Li, Mark Cascione, Juanzhi Fang, Fernando Dangond and Aaron Miller

    Citation: BMC Neurology 2018 18:68

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  25. Content type: Research article

    The principal biomarker of neurodegeneration in multiple sclerosis (MS) is believed to be brain volume, which is associated with cognitive functions and retinal nerve fibre layer (RNFL). A cross-sectional and ...

    Authors: Jessica Frau, Giuseppe Fenu, Alessio Signori, Giancarlo Coghe, Lorena Lorefice, Maria Antonietta Barracciu, Vincenzo Sechi, Federico Cabras, Mauro Badas, Maria Giovanna Marrosu and Eleonora Cocco

    Citation: BMC Neurology 2018 18:67

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  26. Content type: Research article

    HIV is a neurotropic virus, and it can bring about neurodegeneration and may even result in cognitive impairments. The precise mechanism of HIV-associated white matter (WM) injury is unknown. The effects of mu...

    Authors: Rui-li Li, Jun Sun, Zhen-chao Tang, Jing-ji Zhang and Hong-jun Li

    Citation: BMC Neurology 2018 18:66

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  27. Content type: Research article

    Posterior cortical atrophy (PCA) is a group of clinical syndromes characterized by visuospatial and visuoperceptual impairment, with memory relatively preserved. Although PCA is pathologically almost identical...

    Authors: Jieying Li, Liyong Wu, Yi Tang, Aihong Zhou, Fen Wang, Yi Xing and Jianping Jia

    Citation: BMC Neurology 2018 18:65

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  28. Content type: Case report

    POEMS syndrome is a plasma cell disorder, which clinically manifests from paraneoplastic syndrome: polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes. The most comm...

    Authors: Panitha Jindahra, Charungthai Dejthevaporn, Pimjai Niparuck, Jariya Waisayarat, Piyaphon Cheecharoen, Thanatporn Threetong, Purit Petpiroon, Tharikarn Sujirakul, Anuchit Poonyathalang and Kavin Vanikieti

    Citation: BMC Neurology 2018 18:64

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  29. Content type: Study protocol

    Motor outcomes of children with unilateral cerebral palsy are clearly documented and well understood, yet few studies describe the cognitive functioning in this population, and the associations between the two...

    Authors: Brian Hoare, Michael Ditchfield, Megan Thorley, Margaret Wallen, Jenny Bracken, Adrienne Harvey, Catherine Elliott, Iona Novak and Ali Crichton

    Citation: BMC Neurology 2018 18:63

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  30. Content type: Case report

    Some metabolic disorders, including abnormal calcium metabolism, can develop and worsen parkinsonism. However, whether hyperparathyroidism can cause parkinsonism remains controversial.

    Authors: Yuichiro Ohya, Masato Osaki, Shota Sakai, Shunsuke Kimura, Chiharu Yasuda, Tetsuro Ago, Takanari Kitazono and Shuji Arakawa

    Citation: BMC Neurology 2018 18:62

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  31. Content type: Research article

    Epilepsy is a major complication of stroke. We aimed to establish whether there is an association between intravenous thrombolysis, intra-arterial thrombolysis and post stroke seizure (PSS) development. Improv...

    Authors: Jillian Naylor, Arthur Thevathasan, Leonid Churilov, Ruibing Guo, Yunyun Xiong, Miriam Koome, Ziyi Chen, Ziyuan Chen, Xinfeng Liu, Patrick Kwan and Bruce C. V. Campbell

    Citation: BMC Neurology 2018 18:61

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  32. Content type: Case report

    Pediatric autoimmune neuropsychiatric disorder after streptococcal infection (PANDAS) is a specific autoimmune response to group-A streptococcal infections in children and adolescents with a sudden onset of ob...

    Authors: A. H. Nave, P. Harmel, R. Buchert and L. Harms

    Citation: BMC Neurology 2018 18:60

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  33. Content type: Case report

    Granulomatosis with polyangiitis (GPA, formerly Wegener’s granulomatosis) is a multisystem vasculitis of small- to medium-sized blood vessels. Cranial involvement can result in cranial nerve palsies and, rarel...

    Authors: James E. Peters, Vivek Gupta, Ibtisam T. Saeed, Curtis Offiah and Ali S. M. Jawad

    Citation: BMC Neurology 2018 18:59

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  34. Content type: Research article

    Persistent and uncontrollable intracranial hypertension (ICH) and difficulty in reducing Cryptococcus count are severe problems in cryptococcal meningitis (CM) patients. The therapeutic effects of ventriculope...

    Authors: Jia Liu, Zhuo-lin Chen, Min Li, Chuan Chen, Huan Yi, Li Xu, Feng Tan and Fu-hua Peng

    Citation: BMC Neurology 2018 18:58

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  35. Content type: Research article

    Endovascular techniques have proven beneficial in the treatment of aneurysmal subarachnoid hemorrhage (aSAH), but with high risk of arterial clotting, emboli and dissection. Platelet activation and alterations...

    Authors: Pauline Perez, Anne-Claire Lukaszewicz, Stephanie Lenck, Rémy Nizard, Ludovic Drouet and Didier Payen

    Citation: BMC Neurology 2018 18:57

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  36. Content type: Research article

    This study aimed to i) examine the frequency of C9orf72 expansions in a cohort of patients with the behavioural variant frontotemporal dementia (bvFTD) phenocopy syndrome, ii) observe outcomes in a group of pheno...

    Authors: E. Devenney, T. Swinn, E. Mioshi, M. Hornberger, K. E. Dawson, S. Mead, J. B. Rowe and J. R. Hodges

    Citation: BMC Neurology 2018 18:56

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  37. Content type: Case report

    Creutzfeldt-Jakob disease is a rare and fatal neurodegenerative disorder that affects mammals and humans. The prevalence of this disease in the United States is 0.5 to 1 per million inhabitants. So far in Ecua...

    Authors: Germaine Eleanor Torres Herrán, Andrés Damián Ortega Herrera, Braulio Martinez Burbano, Marcos Serrano-Dueñas, María Angélica Ortiz Yepez, Raúl Alberto Barrera Madera, Luis Alfredo Masabanda Campaña, Guillermo David Baño Jiménez, Denny Maritza Santos Saltos and Edgar Patricio Correa Díaz

    Citation: BMC Neurology 2018 18:55

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    The Correction to this article has been published in BMC Neurology 2018 18:84

  38. Content type: Case report

    Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disease. Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is...

    Authors: Keita Miyake, Takashi Hara, Etsuko Oshima, Kiyohiro Kawada, Hideki Ishizu, Yuko Yamauchi, Katsuya Satoh, Tetsuyuki Kitamoto, Shintaro Takenoshita, Seishi Terada and Norihito Yamada

    Citation: BMC Neurology 2018 18:54

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  41. Content type: Research article

    It is usually difficult to identify stroke pathogenesis for single lenticulostriate infarction with nonstenotic middle cerebral artery (MCA). Our aim is to differentiate the two pathogeneses, non-branch athero...

    Authors: Li-Li Sun, Zhong-Hao Li, Wen-Xiong Tang, Lei Liu, Fei-Yan Chang, Xue-Bin Zhang, Wei-Jie Ye, Shuo Lu, Zun-Jing Liu and Xian-Jin Zhu

    Citation: BMC Neurology 2018 18:51

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  42. Content type: Research article

    Caregiver burden may be either a predictor or an outcome of caregiver quality of life (QoL). Patient or caregiver factors that directly affect caregiver QoL, predictors that are simultaneously shared with care...

    Authors: Yu-Hsia Tsai, Meei-Fang Lou, Tsui-Hsia Feng, Tsung-Lan Chu, Ying-Jen Chen and Hsueh-Erh Liu

    Citation: BMC Neurology 2018 18:50

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  44. Content type: Research article

    Congenital sphingosine-1-phosphate (S1P) lyase deficiency due to biallelic mutations in SGPL1 gene has recently been described in association with primary adrenal insufficiency and steroid-resistant nephrotic syn...

    Authors: Gulin Sunter, Ece Oge Enver, Azad Akbarzade, Serap Turan, Pinar Vatansever, Dilek Ince Gunal, Goncagul Haklar, Abdullah Bereket, Kadriye Agan and Tulay Guran

    Citation: BMC Neurology 2018 18:48

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  45. Content type: Research article

    Neuromyelitis optica (NMO) spectrum disorder (NMOSD) is a devastating autoimmune inflammatory disorder of the central nervous system, which can result in blindness or paralysis. Currently, there is a dire need...

    Authors: Yujuan Jiao, Lei Cui, Weihe Zhang, Chunyu Zhang, Yeqiong Zhang, Xin Zhang and Jinsong Jiao

    Citation: BMC Neurology 2018 18:47

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  46. Content type: Research article

    The general principles in the administration of anesthetic drugs entail not only the suppression of seizure activity but also the achievement of electroencephalography burst suppression (BS). However, previous...

    Authors: Kanitpong Phabphal, Suparat Chisurajinda, Thapanee Somboon, Kanjana Unwongse and Alan Geater

    Citation: BMC Neurology 2018 18:46

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  47. Content type: Case report

    Vertebrobasilar dolichoectasia (VBD) is a clinical entity associated with ischemic stroke, compression of cranial nerves or brainstem, and hydrocephalus. There have been relatively few studies following the pr...

    Authors: Dao Pei Zhang, Yan Fang Peng, Qian Kun Ma, Min Zhao, Huai Liang Zhang and Suo Yin

    Citation: BMC Neurology 2018 18:45

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  48. Content type: Case report

    Hepatic encephalopathy may manifest by a wide spectrum of neuropsychiatric symptoms, including cognitive impairment, seizures or extrapyramidal symptoms. The liver transplant can lead to improvement of the sig...

    Authors: Karin Gmitterová, Michal Minár, Miroslav Žigrai, Zuzana Košutzká, Alice Kušnírová and Peter Valkovič

    Citation: BMC Neurology 2018 18:44

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  49. Content type: Research article

    The objective of this study was to compare the changes in the electroencephalogram (EEG) in response to noxious stimuli with tail flick and hot plate responses of rats administered opiorphin.

    Authors: Preet Singh, Kavitha Kongara, David Harding, Neil Ward, Venkata Sayoji Rao Dukkipati, Craig Johnson and Paul Chambers

    Citation: BMC Neurology 2018 18:43

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  50. Content type: Case report

    Idiopathic basal ganglia calcification (IBGC) is a rare neurodegenerative disorder characterized by symmetric intracranial calcium deposition. We report a patient with IBGC associated with cerebral infarction ...

    Authors: Takuma Nishimoto, Fumiaki Oka, Hideyuki Ishihara, Mizuya Shinoyama and Michiyasu Suzuki

    Citation: BMC Neurology 2018 18:42

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